Systemic Immune-Inflammation Index (SII) vs. Neutrophil-to-Lymphocyte Ratio (NLR): evaluating the predictive power of SII and NLR in severity of acute ischaemic stroke based on NIH... by Arbaz Hassan, Anfal Hamza, Kiran Khan, Aiza Shafique, Faiza Naz, Rameen Riaz, Fazeel Shabbir, Muhammad Zafar Majeed Babar, Muhammad Saleem, Hafiz Haseeb Ahsan, Ghulam Mustafa, Hafiz Muhammad Usama Amjad

“…Hypertension (76%) was the most prevalent comorbid condition followed by diabetes mellitus (41%) and family history (32%). …”
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One Health interventions and challenges under rural African smallholder farmer settings: A scoping review by Evanson R. Omuse, Honest Machekano, Bonoukpoè M. Sokame, Daniel M. Mutyambai, Thomas Dubois, Sevgan Subramanian, Frank Chidawanyika

“…Based on the many evidence gaps, the OH initiatives must address health challenges mostly encountered by smallholder farmers with an increased focus on food security and safety, especially under the ongoing climate change. …”
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Assessing Dynamic Cognitive Function in the Daily Lives of Youths With and Without Type 1 Diabetes: Usability Study by Mary Katherine Ray, Jorie Fleming, Andrew Aschenbrenner, Jason Hassenstab, Brooke Redwine, Carissa Burns, Ana Maria Arbelaez, Mary Ellen Vajravelu, Tamara Hershey

“… Abstract BackgroundStudies have shown a relationship between worse glycemic control and lower cognitive scores in youths with type 1 diabetes (T1D). However, most studies assess long-term glucose control (eg, years-decades) and cognition at a single time point. …”
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Evaluating the Performance of State-of-the-Art Artificial Intelligence Chatbots Based on the WHO Global Guidelines for the Prevention of Surgical Site Infection: Cross-Sectional St... by Tianyi Wang, Ruiyuan Chen, Baodong Wang, Congying Zou, Ning Fan, Shuo Yuan, Aobo Wang, Yu Xi, Lei Zang

“… Abstract BackgroundSurgical site infection (SSI) is the most prevalent type of health care–associated infection that leads to increased morbidity and mortality and a significant economic burden. …”
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Quantitative lung ultrasound to guide surfactant retreatment in preterm neonates born at ≤30 weeks’ gestation: a multicentre retrospective non-inferiority diagnostic accuracy study... by Daniele De Luca, Almudena Alonso-Ojembarrena, Davide Sarcina, Irene Gutierrez-Rosa, Barbara Loi, Fiorella Migliaro, Letizia Capasso, Francesco Raimondi

“…Summary: Background: The most critically ill neonates may require repeated surfactant doses, but there are no consensus criteria for retreatment. …”
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Primary care practices’ choice of implementation strategy for continuous glucose monitoring for patients with diabetes: a multiple methods study within a larger hybrid type-3 effec... by Kimberly T. Wiggins, Tristen L. Hall, Bonnie Jortberg, W. Perry Dickinson, L. Miriam Dickinson, Jessica A. Parascando, Douglas H. Fernald, Chelsea Sobczak, Sean M. Oser, Tamara K. Oser

“…Abstract Background Most diabetes care occurs in primary care. Continuous glucose monitoring (CGM) is associated with clinical, behavioral, and psychosocial benefits. …”
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Results of modern radiation-hygienic surveys of settlements of Bryansk Oblast of the Russian Federation bordering the Republic of Belarus. Part 2: Population’s food preferences (di... by I. K. Romanovich, A. B. Bazyukin, A. A. Bratilova, G. Ya. Bruk, K. V. Varfolomeeva, E. A. Drozdova, T. V. Zhesko, M. V. Kaduka, T. A. Kormanovskaya, O. S. Kravtsova, A. V. Kudryashov, A. A. Ladik, V. A. Lalayan

“…Similarly with previous years, among agricultural food products the most consumed products are milk and potatoes and among natural food products are mushrooms. …”
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Is a single calibration for the TloadDback cognitive fatigue induction task reliable? by Jeromy Michael Hrabovecky, Jeromy Michael Hrabovecky, Xavier De Tiège, Xavier De Tiège, Chloé Samyn, Guillermo Borragán, Philippe Peigneux, Mélanie Strauss, Hichem Slama, Hichem Slama

“…., performance improvement) with the most salient between sessions 1 and 2 (t = 3.98, p = 0.0003***). …”
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A genome-wide association study in 10,000 individuals links plasma N-glycome to liver disease and anti-inflammatory proteins by Sodbo Sharapov, Anna Timoshchuk, Olga Zaytseva, Denis E. Maslov, Anna Soplenkova, Elizaveta E. Elgaeva, Evgeny S. Tiys, Massimo Mangino, Clemens Wittenbecher, Lennart Karssen, Maria Timofeeva, Arina Nostaeva, Frano Vuckovic, Irena Trbojević-Akmačić, Tamara Štambuk, Sofya Feoktistova, Nadezhda A. Potapova, Viktoria Voroshilova, Frances Williams, Dragan Primorac, Jan Van Zundert, Michel Georges, Karsten Suhre, Massimo Allegri, Nishi Chaturvedi, Malcolm Dunlop, Matthias B. Schulze, Tim Spector, Yakov A. Tsepilov, Gordan Lauc, Yurii S. Aulchenko

“…Abstract More than a half of plasma proteins are N-glycosylated. Most of them are synthesized, glycosylated, and secreted to the bloodstream by liver and lymphoid tissues. …”
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Utility of serum cytokine testing to differentiate complicated common variable immunodeficiency in resource limited settings by Aditi Jogdand, BS, Karen M. Gilbert, PhD, Joseph S. Hong, BS, Andrew J. Pak, BS, Katherine Liu, BA, Uhuru Kamau, MS, Neha V. Khairnar, MS, MBA, Henry C. Ssemaganda, MD, MS, Daniel DiGiacomo, MD, MPH, Sara Barmettler, MD, MPH, Mei-Sing Ong, PhD, Jocelyn R. Farmer, MD, PhD

“…Background: Common variable immunodeficiency (CVID) is the most common, symptomatic inborn error of immunity (IEI) worldwide. …”
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Multi-omics exploration of chaperone-mediated immune-proteostasis crosstalk in vascular dementia and identification of diagnostic biomarkers by Wentong Li, Yiyi Zhang, Chuanhong Li, Mingyang Jiang, Dong Wang, Luomeng Chao, Luomeng Chao, Luomeng Chao, Yuxia Yang

“…IntroductionVascular dementia (VaD), the second most prevalent form of dementia globally, remains insufficiently understood in terms of its molecular mechanisms and diagnostic biomarkers. …”
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Anti-Virulence Efficacy of Chinese Dragon’s Blood Against Pseudomonas aeruginosa Isolated from Wound Infections by Shen Y, Gu Z, Li Y, Zhou H, Zhu S, Sheng L, Qiang X, Zheng X

“…Empiric therapy of infected wounds with Chinese dragon’s blood (CDB) is one of the most precious traditional Chinese medicines used in clinical settings. …”
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The distribution of aerobic bacteria in Chinese cropland is linked to the soil texture by Xiao Jiamin, Wu Haonan, Xu Chao, Hu Yajun, Xu Zhiwen, Zhang Dongxu, Li Abo, Li Abo, Wei Xiaomeng, Ge Tida, Wei Gehong

“…The results suggest a significant correlation between soil texture and most of these biomarkers. Additionally, the biomarkers in black soil were mainly r-strategists, which include Proteobacteria, Actinobacteria, and Bacteroidetes, were positively correlated with soil organic carbon content. …”
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Genomic data suggest parallel dental vestigialization within the xenarthran radiation by Emerling, Christopher A, Gibb, Gillian C, Tilak, Marie-Ka, Hughes, Jonathan J, Kuch, Melanie, Duggan, Ana T, Poinar, Hendrik N, Nachman, Michael W, Delsuc, Frédéric

“…We tested these competing hypotheses by examining 11 core dental genes in most living species of Xenarthra, characterizing shared inactivating mutations and patterns of relaxed selection during their radiation. …”
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Global burden of vaccine-associated Guillain-Barré syndrome over 170 countries from 1967 to 2023 by Yi Deun Jeong, Seoyoung Park, Sooji Lee, Woojin Jang, Jaeyu Park, Kyeongmin Lee, Jinseok Lee, Jiseung Kang, Raphael Udeh, Masoud Rahmati, Seung Geun Yeo, Lee Smith, Hayeon Lee, Dong Keon Yon

“…Cumulative reports of vaccine-associated GBS have been increasing steadily over time, with a notable surge observed since the commencement of COVID-19 vaccines administration in 2020. Most vaccines showed significant associations with GBS such as Ad5-vectored COVID-19 vaccines (ROR, 14.88; IC, 3.66), COVID-19 mRNA vaccines (ROR, 9.66; IC, 2.84), and inactivated whole-virus COVID-19 vaccines (ROR, 3,29; IC 1.69). …”
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Prevalence of hepatitis B virus infection and associated factors among students living on campus in South-eastern Gabon by Augustin Mouinga-Ondeme, Moussa Yaro, Guy-Roger Ndong Atome, Madeleine Meba, Neil Michel Longo-Pendy, Roseanne Mounanga Mourimarodi, Christ Eddy Ognari Ayoumi, Abdoulaye Diane, Jeordy Dimitri Engone-Ondo, Eldridge Fedricksen Oloumbou, Ivan S. Mfouo Tynga

“…Results With an infection sero-prevalence rate of 5.6% from a total of 462 participants, mostly undergraduates, 26- and 184-samples tested positive for HBsAg- and Anti-HBc-markers, respectively. …”
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Efficacy and safety of nanoparticle albumin-bound paclitaxel plus cisplatin or nedaplatin plus tegafur/gimeracil/oteracil as induction chemotherapy regimen for hypopharyngeal cance... by Cailing Jiang, Yulan Liu, Yunyan Mo, Lieyin Xu, Lin Zhu, Zhenya Li, Shengyuan Xu, Xi Qin, Guangteng Wu, Mafei Kang, Xiaosong He, Feng Xue

“…At the 17.43-month median follow-up, median progression-free survival was 17.6 months (95% confidence interval, 13.9-21.2). The most common grade 3 treatment-related adverse events were alopecia (36.8%), leukopenia (26.3%), and anemia (15.8%). …”
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Primary aortic coarctation repair in adolescents and adultsCentral MessagePerspective by Matthew A. Thompson, MD, William C. Frankel, MD, Jonathan Putnam, BS, Holliann Willekes, MD, Benjamin Kramer, DO, PhD, Ashley M. Lowry, MS, Tara Karamlou, MD, MSc, Patcharapong Suntharos, MD, Joanna Ghobrial, MD, Lars G. Svensson, MD, PhD, Eugene H. Blackstone, MD, Eric E. Roselli, MD

“…Twelve-year freedom from reintervention was 69% in the stented group and 97% in the grafted group (P log-rank = .003). Most reinterventions were for in-stent restenosis of bare metal stents. …”
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Guanfacine extended release for children and adolescents with attention-deficit/hyperactivity disorder: efficacy following prior methylphenidate treatment by Huss M, Sikirica V, Hervás A, Newcorn J, Harpin V, Robertson B, Murkett K

“…Of 163 RCT and 296 RWS participants who had previously received stimulant treatment, 142 and 224, respectively, had received methylphenidate (MPH); due to the low number of participants and the heterogeneity of non-MPH treatments, we only report data for prior MPH treatment. The most frequent reasons for stopping MPH were lack of effectiveness or side effects. …”
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Outcomes following single level posterior lumbar fusion in patients with systemic and discoid lupus: A retrospective national database study by Meera M. Dhodapkar, MD, MHS, Scott J. Halperin, MD, MHS, Wesley Day, BA, Comron Saifi, MD, Daniel R. Rubio, MD, Fotios Koumpouras, MD, Jonathan N. Grauer, MD, Arya Varthi, MD

“…On multivariable analysis of the matched populations, patients with SLE were at most increased odds of 90-day (in decreasing ORs): pneumonia (OR 4.45), urinary tract infection (OR 4.24), minor adverse events (OR 3.17), all adverse events (OR 2.78), deep vein thrombosis (OR 2.71), acute kidney injury (OR 2.62), transfusion (OR 2.08), pulmonary embolism (OR 1.98), sepsis (OR 1.66), surgical site infection (OR 1.29) (p<.0033 for all). …”
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