Transcriptional, growth factors, components of the AKT/mTOR signaling pathway, receptors and ligands of programmed cell death expression in melanoma by K. V. Nikulnikov, V. A. Bogdanova, L. V. Spirina, S. Yu. Chizhevskaya, I. V. Kondakova, E. L. Choynzonov, V. I. Chernov

“…Introduction. Melanoma is the most dangerous neoplasm of the skin, characterized by a malignant and aggressive course. …”
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Antagonistic effect of Pseudomonas aeruginosa on Candida auris by Ana Beatriz N. Macedo, Daniele de Figuerêdo Silva, Anthony G. J. Medeiros, Gustavo José Freitas, Murilo Moreira dos Santos, Kelly Ishida, Nalu Teixeira de Aguiar Peres, Nalu Teixeira de Aguiar Peres, Daniel Assis Santos, Daniel Assis Santos, Luana Rossato, Gustavo H. Goldman, Gustavo H. Goldman, Rafael Wesley Bastos, Rafael Wesley Bastos

“…Fluorescence microscopy suggested that this antagonistic effect was predominantly fungistatic, as most C. auris cells remained viable in the presence of the bacterium. …”
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Mangrove composition and anthropogenic marine debris survey in Camotes Group of Islands, Philippines by Maximino III Abejo, Arnel Nudalo, Martha Joyce Garciano, Ian Paul Bayon, Chembelyn Gella Bayon, Marvin Guinocor, Jesrael Linao, Althea Mae Guevara, Christine Caya, Sylvester Tan Cortes

“…The families Rhizophoraceae and Lythraceae were the most represented. Notably, two species, Sonneratia ovata (near threatened) and Avicennia rumphiana (vulnerable), were recorded, indicating the urgency of focused conservation efforts. …”
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Integrative proteogenomic characterization of Wilms tumor by Cheng Cheng, Li Zhang, Xiaofeng Chang, Kai Chen, Tian He, Jia Shi, Fan Lv, Lijia Pan, Yangkun Wu, Qianqian Cheng, Dong Ren, Yongli Guo, Weiping Zhang, Huanmin Wang, Tieliu Shi, Jing Li, Xin Ni, Yeming Wu, Yaqiong Jin, Zhixiang Wu

“…Abstract Wilms tumor (WT), the most common pediatric renal malignancy, exhibits a relatively low mutational burden compared to adult cancers, which hinders the development of targeted therapies. …”
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Identifying Key Pathogens and Effective Control Agents for <i>Astragalus membranaceus</i> var. <i>mongholicus</i> Root Rot by Bo Zhang, Bingyan Xia, Chunyan Wang, Ouli Xiao, Tielin Wang, Haoran Zhao, Xiaofeng Dai, Jieyin Chen, Yonggang Wang, Zhiqiang Kong

“…Root rot is one of the most serious diseases affecting <i>Astragalus membranaceus</i>, significantly reducing its yield and quality. …”
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Minimally invasive ultrasound-guided biopsy of the common extensor tendon enthesis: a cadaveric study to standardise the technique by Ingrid Moller, Georg Schett, Andreas Ramming, Giuliana Guggino, Stefano Alivernini, Pietro Rubortone, Carlo Tur, Enrico De Lorenzis, Beatrice Belmonte, Maria Antonietta D’Agostino, Maria Gabriella Raimondo, Chiara Rizzo, Marco Maria Lizzio, Luis Coronel, Maribel Miguel Perez, Valeria Cancila

“…Histology and immunohistochemistry indicated that most of the samples exhibited characteristics consistent with entheseal tissue (21 out of 24). …”
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CXCL16 Producing Tumor Clones Are Shaping Immunosuppressive Microenvironment in Squamous Cell Carcinoma via CXCR6 Regulatory T Cell by Hyun Seung Choi, Sunyoung Jung, Ki‐Myo Kim, Mihyun Lee, Jun Ho Park, Sanha Hwang, Seung Min Cha, Jade N. Young, Dina Poplausky, Hyunsung Nam, Nicholas Gulati, Chung‐Gyu Park, Hyun Je Kim, Ji‐Ung Park

“…ABSTRACT Background Cutaneous squamous cell carcinoma (cSCC) and basal cell carcinoma (BCC) are the most prevalent types of nonmelanoma skin cancer (NMSC) and exhibit significant inter‐ and intra‐tumor heterogeneity. cSCC has a higher metastatic potential than BCC, accompanied by a considerable mortality rate. …”
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Clinical application of polar body-based preimplantation genetic testing for maternal mutations in women with a limited number of oocytes by Jia Chen, Xingwu Wu, Qiang Xu, Tao Ding, Ge Chen, Houyang Chen, Yongyi Zou, Jialyu Huang, Ziyu Zhang, Lifeng Tian, Yan Zhao, Ranhui Duan, Zengming Li, Qiongfang Wu, Yanqiu Liu

“…Abstract Background Trophectoderm (TE) cell biopsy at the blastocyst stage is currently the most common method used in preimplantation genetic testing for monogenic disorders (PGT-M). …”
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Antibodies against post-translationally modified vimentin peptides in patients with rheumatoid arthritis by P. A. Kuznetsova, A. L. Maslyanskiy, S. V. Lapin, A. V. Mazing, H. Bang, V. I. Mazurov

“…Rheumatoid arthritis (RA) is the most common autoimmune rheumatic disease (ARD) associated with the production of broad-spectrum antibodies, the detection of which is of important diagnostic and prognostic values. …”
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Simulating the ENSO impact on the distribution and fate of floating litter particles in the Northern South China Sea by Ke Pang, Ke Pang, Ke Pang, Yang Feng, Yang Feng, Yang Feng, Youchang Zheng, Youchang Zheng, Youchang Zheng, Chao Fang, Xiangrong Xu, Xiangrong Xu

“…The model reveals that most floating litter remains within Lingding Bay before being transported westward by the counterclockwise circulation over the NSCS and arriving at the Qiongzhou Strait. …”
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Epidemiological Features of Obesity and Type 2 Diabetes Mellitus in the Russian Federation by Yu. S. Sytaya, A. Yi. Mindlina

“…The incidence of obesity among the children from 0 to 14 years was 370,99 per 100 ths, while the most unfavorable epidemic situation was noted in the North-Western FD (476,86 per 100 ths – exceeding the level in Russia by 1,29 times). …”
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Targeting miR-21 decreases expression of multi-drug resistant genes and promotes chemosensitivity of renal carcinoma by Kelly Gaudelot, Jean-Baptiste Gibier, Nicolas Pottier, Brigitte Hémon, Isabelle Van Seuningen, François Glowacki, Xavier Leroy, Christelle Cauffiez, Viviane Gnemmi, Sébastien Aubert, Michaël Perrais

“…Renal cell carcinoma, the most common neoplasm of adult kidney, accounts for about 3% of adult malignancies and is usually highly resistant to conventional therapy. …”
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Impacto da radioterapia adjuvante no resultado cosmético da reconstrução mamária imediata com retalho TRAM Impact of adjuvant radiotherapy on the cosmetic outcome of immediate brea... by Salustiano Gomes de Pinho Pessoa, Juliana Régia Furtado Matos, Iana Silva Dias, Diego Tomaz Teles Peixoto, Jéssica Silveira Araújo

“…Two (8%) patients exhibited flap contracture and volume loss, whereas skin changes were observed in 52% of patients. Most of the patients (84%), however, had no significant initial flap volume loss, contour distortion, or flap contraction . …”
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Improving the accuracy of emergency department clinicians in detecting SARS-COV-2 on chest X-rays using a bespoke virtual training platform by Jasdeep Bahra, Anita Acharya, Sarim Ather, Rachel Benamore, Julie-Ann Moreland, Divyansh Gulati, Lee How, Thandiwe Rosemarysdottir, Miranthi Huwae, Sarah Wilson, Abhishek Banerji, Katerina Manso, Liza Keating, Amy Barrett, Fergus Gleeson, Alex Novak

“…Abstract Background During and after the COVID pandemic, online learning became a key component in most undergraduate and post-graduate training. The non-specific symptoms of SARS-CoV-2 and limitations of available diagnostic tests can make it difficult to detect and diagnose in acute care settings. …”
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Optical Properties and Molecular Composition of Fine Organic Aerosols in Nanjing, China: A Comparison of 2019 and 2023 by Binhuang Zhou, Yu Huang, Liangyu Feng, Zihao Zhang, Haiwei Li, Yun Wu, Jianhuai Ye, Xinlei Ge

“…Overall, CHON compounds were the most abundant species, followed by CHO and CHN compounds, and aliphatic compounds dominated all molecular types except for CHN (in positive mode) and CHON, CHOS (in negative mode). …”
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COVID- 19 vaccine uptake and its determinants in Cameroon: a systematic review and meta-analysis (2021–2024) by Fabrice Zobel Lekeumo Cheuyem, Adidja Amani, Chabeja Achangwa, Brian Ngongheh Ajong, Claude Axel Minkandi, Myriam Mathilde Mbia Kouda Zeh, Larissa Linda Eyenga Ntsek, Jacques Philippes Essomba, Rudy Chiozem Jiogue, Olivier Ndagijimana, Ndzi Etienne Nchanji, Celestin Danwang

“…The results of this meta-analysis underline the crucial need to step up efforts to improve vaccination coverage, particularly among the most vulnerable populations. Identifying and addressing the factors underlying this low coverage is imperative if public health objectives are to be met. …”
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Examining Patient Characteristics Associated With Digital Outpatient Care for Type 1 Diabetes (DigiDiaS): Cross-Sectional Study by Ingeborg Spildo, Heidi Holmen, Annesofie Lunde Jensen, Milada Hagen, Tone Singstad, Jacob Andreas Winther, Eirik Årsand, Astrid Torbjørnsen

“…ConclusionsThis study reveals that most patients with type 1 diabetes choose digital outpatient care when it is offered. …”
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Comprehensive rehabilitation of patients with early rheumatoid arthritis: results of 6-month program by Evgenia Vladislavovna Orlova, D E Karateev, A V Kochetkov

“…Following 6 months, the changes in the control group were less significant, which determined significant differences between the groups in most indicators. Conclusion. Six-month CRP enhances compliance with drug and non-drug treatments, assists in controlling disease activity, and improves functional abilities, motor activity, and quality of life in patients with early RA. …”
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The Role of Childhood Abuse and Social Health on Bullying among Prisoners by Mahnaz Farahmand, Hanieh Tayebi

“…The findings revealed that 46.5% of prisoners reported moderate to high levels of bullying, while 53.3% reported low levels. The most common forms of bullying included the use of sexual epithets and gestures, as well as inciting hatred towards victims. …”
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Comparison of Mallampati test in supine and upright positions with and without phonation in predicting difficult laryngoscopy and intubation in age groups 3-10 years. by P. Awasthi, S. Gautam, A. Malik, V. Singh, M. Kohali, S. Jafa, J. Agarwal

“…Results In this study, the ROC curve analysis found Mallampati test in upright without phonation (AUC=0.959, Z=5.68, p<0.001) is the most significant in predicting difficult laryngoscopy compared to other positions. …”
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