SURGICAL TACTICS REGARDING CEREBRAL METASTASES WITH HEMORRHAGES by E. V. Prozorenko, V. B. Karakhan, A. Kh. Bekyashev, V. A. Alyoshin, D. M. Belov, D. R. Naskhletashvili, N. V. Sevyan, A. A. Mitrofanov

“…Hemorrhages into cerebral metastases are one of the most dangerous complications of the metastatic process. …”
Get full text

Breaking Barriers: The Detrimental Effects of Combined Ragweed and House Dust Mite Allergen Extract Exposure on the Bronchial Epithelium by Răzvan-Ionuț Zimbru, Manuela Grijincu, Gabriela Tănasie, Elena-Larisa Zimbru, Florina-Maria Bojin, Roxana-Maria Buzan, Tudor-Paul Tamaș, Monica-Daniela Cotarcă, Octavia Oana Harich, Raul Pătrașcu, Laura Haidar, Elena Ciurariu, Karina Cristina Marin, Virgil Păunescu, Carmen Panaitescu

“…Transepithelial electrical resistance (TEER) was recorded over 72 hours to assess barrier integrity, and immunofluorescence (IF) staining for zonula occludens-1 (ZO-1) was performed to evaluate tight junction alterations. (3) Results: TEER measurements showed a significant reduction in epithelial barrier integrity following allergen exposure, with the most pronounced disruption observed with the combined exposure to RW and HDM groups. …”
Get full text

Mapping soil drainage classes: Comparing expert knowledge and machine learning strategies by Danilo César de Mello, Nélida E.Q. Silvero, Bradley A. Miller, Nicolas Augusto Rosin, Jorge Tadeu Fim Rosas, Bruno dos Anjos Bartsch, Gustavo Vieira Veloso, Jean Jesus Macedo Novais, Renan Falcioni, Marcos Rafael Nanni, Marcelo Rodrigo Alves, Elpídio Inácio Fernandes-Filho, Uemeson José dos Santos, José Alexandre Melo Demattê

“…Given its higher interpretability and ease of application, the EK approach was recommended as the most suitable for operational soil drainage mapping in tropical environments.…”
Get full text

Cohort profile: pulmonary early assessment of the lung in paediatric cancer patients (SWISS-PEARL Study) by Christine Schneider, Gabriele Raffler, Maša Žarković, Christina Schindera, Jochen Rössler, Claudia E. Kuehni, Philipp Latzin, Alexander Moeller, Rahel Heule, Jakob Usemann, on behalf of the SWISS-PEARL study group

“…Mean age at diagnosis was 12 years (range 4–18). The most common cancer diagnoses were leukaemia (41%) and lymphoma (23%). …”
Get full text

The combined effect of a newly designed biostimulant and a plant growth-promoting bacterium increases tomato yield under salt stress by increasing the cytokinin isopentenyladenine... by Patricia Benito, Sara Trigueros, Marina Celdrán, Valeria Sánchez, Alberto Coronado, Javier Bellón, Vicente Arbona, Miguel González-Guzmán, Rosa Porcel, Lynne Yenush, José M. Mulet

“…In addition, the joint treatment increased the content of the cytokinin isopentenyladenine riboside (IPR) in roots and leaves and promoted a significant accumulation of Krebs cycle intermediates under salt stress. The most plausible mechanism is that cytokinins protect chloroplasts and photosynthetic function, increasing the available sugar. …”
Get full text

Analisis Pengalaman Pengguna Learning Management System (LMS) "ELING" Menggunakan Metode Ux Curve (Studi Kasus Mahasiswa Program Studi Sistem Informasi Fakultas Ilmiu Komputer Uni... by Muhammad Haris Setiawan, Hanifah Muslimah Az-Zahra, Retno Indah Rokhmawati

“…Thus, the first to third months of use is the most influential on the changes of the user experience of the LMS. …”
Get full text

Interpretable prediction of hospital mortality in bleeding critically ill patients based on machine learning and SHAP by Bingkui Ren, Yuping Zhang, Siying Chen, Jinglong Dai, Junci Chong, Yifei Zhong, Mengkai Deng, Shaobo Jiang, Zhigang Chang

“…SHAP analysis identified the top 15 predictors of mortality, with bilirubin level ranked as the most influential variable.​​ External validation using the REFRAIN cohort confirmed the robustness of model(AUC = 0.776). …”
Get full text

Healing from the wild: an ethnozoological exploration of animal-based medicine in Jhargram, West Bengal, India by Rakesh Acharya, Sanjib Kumar Das, Ankur Bhowal, Koushik Sen

“…Common preparation methods included cooking, boiling, roasting, and frying, with oral administration being the most frequently used method, followed by topical, inhalation and anal applications. …”
Get full text

Challenges of Statin Therapy in Clinical Practice (According to Outpatient Register «PROFILE» Data) by S. Yu. Martsevich, Yu. V. Lukina, N. P. Kutishenko, A. V. Zagrebelnyy, S. N. Tolpygina, V. P. Voronina, N. A. Dmitrieva, O. V. Lerman, E. S. Nekoshnova, I. V. Budaeva, S. V. Blagodatskikh, B. B. Aslanova

“…The main problems of statin treatment in real clinical practice remain the non-assignment of these drugs to patients who have indications for such therapy and the failure to achieve the target levels of lipidogram indicators, which may probably be due to the clinical inertia of doctors regarding titration of statin doses, and in some cases caused by the choice of drugs that are not the most effective in reducing LDL cholesterol. Patients with very high CV risk are 4 times more likely to receive a recommendation to take statins compared to patients with high CV risk, but the target level of LDL cholesterol is reached in them 2 times less often.…”
Get full text

Desempenho de diferentes guias de ondas para uso com o analisador de umidade TRASE Performance of different waveguides for use with the TRASE water content analyser by Eugênio F. Coelho, Camilo de L.T. Andrade, Dani Or, Lucy C. Lopes, Claudinei F. Souza

“…An exponential model was the most suitable in estimating soil water content as a function of bulk dielectric constant for the standard waveguide. …”
Get full text

Clinical and functional evidence for the pathogenicity of the LRRK2 p.Arg1067Gln variant by Shen-Yang Lim, Tzi Shin Toh, Jia Wei Hor, Jia Lun Lim, Lei Cheng Lit, Azlina Ahmad-Annuar, Yi Wen Tay, Jia Nee Foo, Ebonne Yulin Ng, Kalai Arasu Muthusamy, Norlinah Mohamed Ibrahim, Khairul Azmi Ibrahim, Louis Chew Seng Tan, Jannah Zulkefli, Anis Nadhirah Khairul Anuar, Kirsten Black, Pawel Lis, Fei Xie, Zhidong Cen, Kai Shi Lim, Katja Lohmann, Shalini Padmanabhan, Dario R. Alessi, Wei Luo, Eng King Tan, Esther Sammler, Ai Huey Tan

“…Abstract LRRK2-related Parkinson’s disease (LRRK2-PD) is the most frequent form of monogenic PD worldwide, with important therapeutic opportunities, exemplified by the advancement in LRRK2 kinase inhibition studies/trials. …”
Get full text

Comparative study of specific activity of rectal suppositories with clopidogrel by I. L. Kechyn, V. V. Hladyshev, O. L. Drozdov, O. B. Kharaponova, S. A. Hladysheva

“…One of the most effective platelet antiaggregants is clopidogrel, inhibiting platelet activation by selectively binding adenosine diphosphate (ADP) with specific receptors. …”
Get full text

Moringa oleifera extract and rutin prevent monosodium glutamate-induced nephrotoxicity in rats by Doaa M. Abdel-Aty, Sherif R. Mohamed, Wafa A. Al-Megrin, Nashmiah Sindi Alshammari, Mohammed M. Althaqafi, Ali H. Alghamdi, Rami B. Kassab, Mona A. Ibrahim, Ahmed E. Abdel Moneim, Doaa Soliman, Ayah S. Fathalla

“…Administration of MO extract or rutin before MSG significantly ameliorated these changes, with MO extract showing slightly superior effects in most parameters. MO extract reduced serum creatinine by −28.294 % and urea by −20.625 %, while rutin achieved −32.493 % and −29.691 % reductions respectively. …”
Get full text

Irrigated rice-field mapping in Brazil using phenological stage information and optical and microwave remote sensing by Andre Dalla Bernardina Garcia, MD Samiul Islam, Victor Hugo Rohden Prudente, Ieda Del’Arco Sanches, Irene Cheng

“…Analytic results show that the end of season is the most suitable for obtaining a reliable classification based on optical and SAR sensors. …”
Get full text

Potential effects of endocrine-disrupting chemicals on preserved ratio impaired spirometry revealed by five different approaches by Chenyuan Deng, Yu Jiang, Yuechun Lin, Hengrui Liang, Wei Wang, Ying Huang, Jianxing He

“…The results of SHAP interpretability analysis based CatBoost model further highlighted MIBP as the most informative environmental predictor. Conclusion: These findings suggest that exposure to EDCs may be linked to the prevalence of PRISm. …”
Get full text

Genome-Wide Identification of the <i>DOG1</i> Gene Family in Pepper (<i>Capsicum annuum</i>) and Its Expression Profiles During Seed Germination by Zhichao Zhao, Jingbo Sun, Feng Zhang, Chunjuan Dong

“…All <i>CaDOG1</i> genes were unevenly distributed on six <i>C. annuum</i> chromosomes, and they had relatively conserved exon–intron patterns, most with zero to one intron. According to the chromosomal distribution patterns and synteny analysis of the <i>CaDOG1</i> genes, the <i>CaDOG1</i> family expanded mainly through replication, which occurred predominantly after the divergence of dicotyledons and monocotyledons. …”
Get full text

Born to be Starless: Revisiting the Missing Satellite Problem by Seyoung Jeon, Sukyoung K. Yi, Emanuele Contini, Yohan Dubois, San Han, Katarina Kraljic, Sebastien Peirani, Christophe Pichon, Jinsu Rhee

“…In the case of starless subhalos, supernova feedback is irrelevant because most of them do not have in situ star formation in the first place. …”
Get full text

Ultrasonographic Nomograms of Foetal Fourth Ventricle Biometry and its Correlation with Transcerebellar Diameter and Gestational Age among Normal Foetuses: A Cross-sectional Study by N Padmalatha, Paarthipan, Parthasarathy, Francis Nanda Prakash Monteiro

“…Prenatal diagnosis of midbrain and hindbrain abnormalities is based on aberrant cerebellum and retrocerebellar space size and shape, with the most prevalent sign being an ‘open fourth ventricle’. …”
Get full text

Study of water pollution parameters in the dry and rainy seasons on the pollution index of the Mesuji River, Lampung, Indonesia by Abu Rosid Istomi, Suharso, Buhani, Tugiyono, Heri Satria, Emi Artika, Annisaa Siti Zulaicha

“…The water quality index (WQI) indicated poor quality during the dry season (WQI = 30) and moderate quality in the rainy season (WQI = 50). Conclusions: While most stations met COD and DO standards during the rainy season, only one met these standards in the dry season. pH levels failed to meet standards in both seasons, and phosphate levels varied. …”
Get full text

Iodide n,π-chelate complexes of platinum(II) based on N-allyl substituted thioureas and their effect on the activity of hepatobiliary system enzymes in comparison with chloride ana... by V. Orysyk, L. Garmanchuk, S. Orysyk, Yu. Zborovskii, S. Shishkina, I. Stupak, P. Novikova, D. Ostapchenko, N. Khranovska, V. Pekhnyo, M. Vovk

“…It is established that, for the most part, effect of the studied complexes is reduced to a decrease in the degree of malignancy of cells of hepatocyte lines and the activity of LDH and GHT, as well as a decrease in consumed glucose.…”
Get full text