Exploring Missense Variants in the Human PNPLA3 Protein: An In Silico Analysis by Asia Awad AbdelGader, Afra M. Al Bakry, Hind A. Elnasri, Dawelbiet Abdelaal Yahia, Mona Abdelrahman Mohamed Khaier

“…Six nsSNPs were selected for submission to the Project Hope software based on their prediction by SNPs&GO as the most damaging, with a score range of 0.998 to 1.000. …”
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Exploiting Microperimetry as a Functional End Point in Healthy Aging and Different Stages of Age-Related Macular Degeneration by Johannes Schrittwieser, MD, Klaudia Birner, MD, Leonard M. Coulibaly, MD, Ursula Schmidt-Erfurth, MD, Gregor S. Reiter, MD, PhD

“…The range between the highest and lowest PWS was the most effective parameter for discrimination, with a classification accuracy of 52.5% and 50.6% in the MP-3 and MAIA, respectively. …”
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SCIENTIFIC-PROJECT CONSULTING AS AN INNOVATIVE FORMAT OF POSTGRADUATE EDUCATION by G. A. Ignatieva, O. V. Tulupova

“…The forms of post-degree training which are most demanded within scientific and design consulting are described. …”
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Towards Secretome Standardization: Identifying Key Ingredients of MSC-Derived Therapeutic Cocktail by Chiara Giannasi, Stefania Niada, Elena Della Morte, Sara Casati, Marica Orioli, Alice Gualerzi, Anna Teresa Brini

“…At last, lipidomic analysis allowed the quantification of 7 lipids and indicated prostaglandin-E2 and N-stearoylethanolamide as the most homogenous factors. In this study, we assessed that ASC-CM samples obtained with a standardized protocol present stable features spanning from Raman fingerprint to specific marker concentrations. …”
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Selection and validation of reference genes for qRT-PCR in cultivated octoploid strawberry by Jianxin Mao, Jiqi Li, Yan Wang, Zhihong Zhang

“…RefFinder analysis determined that FaGAPC2 and FaADPrf1 were the most suitable reference genes, considering the results obtained from the abovementioned four methods. …”
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Staging growing rod insertion results in increased postoperative complications than the equivalent unstaged procedure by Lily S Switzer, Emma B Nadler, Jennifer A Dermott, Karim Aboelmagd, Alison Anthony, Dorothy J Kim, Mark Camp, David E Lebel

“…Complications were recorded until posterior spinal fusion (PSF) or most recent follow-up if no PSF was performed, and compared between groups. …”
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Combination of the Parasitoid <i>Spalangia endius</i> Walker and Chemical Pesticides for the Control of <i>Zeugodacus cucurbitae</i> (Coquillett) by Lei Li, Dongyin Han, Jing Zhao, Haiyan Qiu, Fangping Zhang, Zhengpei Ye, Yueguan Fu

“…The timing of abamectin soil application relative to host pupation and <i>S. endius</i> release affects host mortality. The most effective timing is spraying abamectin before host pupation (to expose <i>Z. cucurbitae</i> larvae) and then releasing <i>S. endius</i>. …”
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Impacts of urbanization on land use change and its incidences on the climate: Case of Bingerville City (Ivory Coast, West Africa) by Kinanlie Sandrine Traore, Salomon Obahoundje, Asseypo Célestin Hauhouot, Arona Diedhiou

“…As for extreme temperature indices, most show a statistically insignificant trend, except for cold days (TX10p) and hot days (TX90p), which have a statistically significant trend of 0.004 and 0.018, respectively. …”
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Identification of LIMK1 as a biomarker in clear cell renal cell carcinoma: from data mining to validation by Yifei Li, Congcong Fan, Feng Jiang, Jingnan Zhang, Yanzhen Li, Yanjie Jiang, Rui Zhang, Zhixian Yu, Siqi Wang

“…Abstract Purpose Clear cell renal cell carcinoma (ccRCC) is one of the most common types of renal cancer. LIM kinase 1 (LIMK1) reportedly plays an important role in tumorigenesis. …”
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CARDIOVASCULAR HEMODYNAMICS AND SPECIFICS OF 24-HOUR BP PROFILE IN PATIENTS WITH HYPERTROPHIC CARDIOMYOPATHY AND INADEQUATE BP REACTION ON PHYSICAL EXERTION by F. M. Khashieva, A. E. Demkina, N. S. Krylova, E. A. Kovalevskaya, N. G. Poteshkina

“…Presence of IRBP in physical exertion was associated: with more significantdiastolic dysfunction of the left ventricle (LV): the correlation is found with the peak delayed diastolic filling on mitral valve (peak A mv)(r=-0,76, p=0,002), relation of the velocities of early and delayed diastolic filling on the mitral valve (E/A mv) (r=0,53, p=0,03); decreased volume of LV: correlation with end-diastolic volume (EDV); end systolic volume (ESV) (r=-0,55, p=0,03); increased stiffness of arterial wall: correlation with the velocity of pulse wave (PWVao) (r=0,7, p=0,005), ambulatory index of vessel rigidity (MSI) (r=0,49, p=0,05), augmentation index (Axi) (r=-0,51, p=0,04).In discriminate analysis the EDV, E/A and AASI were the most significant predictors of IRBP. The functions were invented that make, by the highest value, an separation of a patients into one of 2 groups: I group (n=10, of those 7 women, mean age 51,4±13,9y.) with IRBP, II group (n=7, of those 6 women, mean age 56,0±9,3y.) with normal reaction of BP to physical exertion.…”
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Modern possibilities of surgical treatment of benign breast tumors with ptosis: comparative analysis and long-term outcomes by R.  M.  Shabaev, I.  V.  Kolyadina, D.  A.  Blagovestnov, P.  M.  Starokon

“…Evaluation of the mental component of quality of life one year after surgery showed a significant advantage of performing surgical treatment in group 1 compared to that in group 2, p &lt;0.001, which is most likely due to the removal of multiple breast tumors with simultaneous elimination of mammary ptosis, which had a positive effect on the psychoemotional state and quality of life of women.Conclusion. …”
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The Role of Caspase-8, MLKL and RIPK1 in Iraqi Patients’ Women with Breast Cancer by Mays Najem Al-Adilee, Hazima Mossa Al-Abassi

“… Background: Breast cancer is the most common type of cancer that affects women’s breast tissue, leading to uncontrollably aberrant cell proliferation. …”
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Molecular characterization and diversity of carbapenemases in Gram-negative bacteria in Libyan hospitals by Khouloud Slimene, Salem K Almahjoub, Aldukali A Alkeskas, Ahmed I Elbousify, Elham O Omar, Allaaeddin A El Salabi, Elhussan A Mohamed, Mohammed I Hameid, Souad Alsanosi, Dhouha Miniaoui, Jean-Marc Rolain, Chedly Chouchani

“…Molecular investigations indicated that NDM-1 was the most prevalent in Enterobacteriaceae isolated from patients and hospital environment (n = 26, n = 41), followed by blaOXA-48 (n = 16, n = 15) and blaVIM (n = 3) from patients and blaKPC (n = 1) from hospital environment. …”
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Interrupted time series analysis of pediatric hospital acquired malnutrition risk score implementation in hospitalized Thai children by Thitichaya Leesurapong, Suchaorn Saengnipanthkul, Prapassara Sirikarn, Phanthila Sitthikarnkha, Leelawadee Techasatian, Rattapon Uppala

“…However, there were no significant long-term trend changes for most outcomes assessed. The PHaM risk score effectively improved immediate key clinical outcomes, reducing HaM, infections, and hospital costs. …”
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Association between beauty standards shaped by social media and body dysmorphia among Egyptian medical students by Mohammed N. Abdelaziz, Ahmed R. A. Moustafa, Hajer Azzam, Anwar M. Bshar, Ismail S. Ismail, Omnia Yousry Elhadidy

“…According to social media practices, WhatsApp, Facebook, Instagram, YouTube, and TikTok were mostly used for 4–7 h daily. Most rarely or sometimes, take selfies, edit them with filters, and share them with others. …”
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Physical activity promotion in the early childcare setting: a content analysis of the federal-state-wide educational framework plans in Germany by Stefanie Do, Maike Till, Sven Messing, Peter Gelius, Mirko Brandes, Jonas D. Finger, Sylke Oberwöhrmann, Sarah Forberger, Antje Hebestreit

“…The objectives focused on competence goals and related policy measures for physical activity promotion. Most of the educational framework plans targeted children up to 6 years and considered different subgroups. …”
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Enhanced immunotherapeutic profile of oncolytic virus-based cancer vaccination using cyclophosphamide preconditioning by Guido Kroemer, AJ Robert McGray, Brian D Lichty, Byram W Bridle, Samuel T Workenhe, Jonathan G Pol, Yonghong Wan, Matthew J Atherton, Kyle B Stephenson, Natasha Kazdhan

“…Despite doubling the median survival in comparison to untreated controls, most vaccinated mice ultimately succumbed to cancer progression. …”
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Dynamics of absorption properties of CDOM and its composition in Likas estuary, North Borneo, Malaysia by Saiyidah Munirah Mohd-Shazali, Jafar-Sidik Madihah, Nurzaliah Ali, Chen Cheng-Ann, Robert J.W. Brewin, Md. Suffian Idris, P. Purba Noir

“…Based on the spectral slope ratio (SR), most of the stations located in the Darau, Inanam, and Bangka-Bangka rivers had SR values less than 1. …”
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Isolation and screening of IAA-producing bacteria from glutinous sorghum leaves and its plant growth-promoting function by WANG Xinye, ZHANG Min, TIAN Xiaolong, YUAN Ping, LI Hongxia, LUO Zhenbiao, YUE Qianqian, ZHAO Liang*

“…Among them, HY1-1 demonstrated the most prominent promotion effect, with a germination rate increase of 165.52%.(4)HY1-1 strain was selected for a pot experiment. …”
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Successful treatment with steroid pulse therapy for a COVID-19 case with progressive respiratory failure during treatment for pleural metastasis of breast cancer by Hikari Jimbo, Yoshiya Horimoto, Makoto Hiki, Yoko Tabe, Junichiro Watanabe, Mitsue Saito, Toshio Naito

“…Although the regulation of immune response is thought to play an important role in the treatment of coronavirus disease 2019 (COVID-19), physicians often have difficulties in selecting the most appropriate treatment. Furthermore, the impact that interrupting breast cancer treatment due to a COVID-19 infection has on patient outcomes is still unknown. …”
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