Molecular subtypes, prognostic factors, and treatment optimization in pediatric medulloblastoma: a real-world study from China by Jingjing Liu, Yanling Sun, Huming Li, Shuxu Du, Jin Zhang, Zhen Zhang, Liming Sun, Wanshui Wu

“…BackgroundMedulloblastoma (MB) is the most common malignant pediatric brain tumor, yet systematic studies on molecular characteristics and treatment efficacy in Chinese pediatric MB remain scarce. …”
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Electrochemically Modified Mn₂P₄O₁₂ as an Emerging Catalyst for Oxygen Evolution Reaction by Kassa Belay Ibrahim, Tommaso Michelutti, Alessandro Gradone, Mahnoor Hassan, Sandro Zorzi, Paolo Moras, Vittorio Morandi, Elisa Moretti, Tofik Ahmed Shifa, Alberto Vomiero

“…However, alkaline water oxidation is the most relevant process at the industrial level, and it faces obstacles due to unfavorable thermodynamics and high overpotential. …”
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Correlations between expression levels of genes encoding multifunctional YB-1 protein, inflammatory cytokines and multidrug resistance P-gp protein in surgical material from patien... by M. V. Erokhina, E. N. Pavlova, E. A. Scherbakova, E. Yu. Rybalkina, L. N. Lepekha, R. V. Tarasov, E. K. Tarasova

“…The aim of our study was to identify the most significant correlations between expression rates of YB-1 gene with expression of some key cytokine genes involved in the regulation of tuberculous inflammation (IL-6, IL-10, IFNγ, TGF-β, TNFα, IL-1β), hypoxia factor-1 (HIF1a) gene, and P-gp protein gene ABCB1 in the patients with pulmonary tuberculosis. …”
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Analysing the context and characteristics of legal abortion and comprehensive post-abortion care among adolescents aged 10–14 in a network of sentinel centres in Latin America: a r... by Caitlin R. Williams, M. Valeria Bahamondes, Rodolfo Gómez Ponce de León, Helymar da Costa Machado, Luis Bahamondes, Sonja Caffe, Suzanne Jacob Serruya

“…Young adolescents were at higher risk of pre-procedure and intra-operative complications than older adolescents and young adults, though the trend is less clear for the most severe complications. In general, the quality of care provided by centres in the network was aligned with WHO recommendations for safe abortion and comprehensive post-abortion care. …”
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Euphemisms in Modern Political Discourse: Joseph Biden’s Speeches in the War in Uk by Nataliia M. Tymoshchuk

“…Biden’s speech is characterized by a short syntagm, as he slows down the pace, trying to convey every word to the audience. The stress is mostly emphatic, with emphasis created by increasing pitch, volume, and duration. …”
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CardioMEMS guided heart failure management in cardio-oncology patients: a tertiary care cancer center experience by Abdelrahman Ali, Maximillian Bourdillon, Hyeon-Ju Ryoo Ali, Juhee Song, Efstratios Koutroumpakis, Poonam Jewani, Shaden Khalaf, Ihab Hamzeh, Salil Kumar, Nicolas L. Palaskas, Jean-Bernard Durand, Cezar Iliescu

“…Results The study included 28 patients, with hypertension (78%) and hyperlipidemia (78%) as prevalent comorbidities. Most patients had heart failure with preserved ejection fraction (64%). …”
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Alkannin Induces G2/M-Phase Arrest, Apoptosis, and Inhibition of Invasion by Targeting GSK3β in Esophageal Squamous Cell Carcinoma by Ma H, Xu P, Jia Y, Zhou Y, Li X, Wang Y, Ma K

“…Huihui Ma,1– 3,* Peng Xu,1– 3,* Yunchao Jia,1,2 Yehan Zhou,1– 3 Xinzhi Li,1,2,4 Yanming Wang,1– 3 Ketao Ma1– 3 1Key Laboratory of Xinjiang Endemic and Ethnic Diseases, Ministry of Education, Shihezi University School of Medicine, Shihezi, 832003, People’s Republic of China; 2NHC Key Laboratory of Prevention and Treatment of Central Asia High Incidence Diseases, First Affiliated Hospital, Shihezi University School of Medicine, Shihezi, 832003, People’s Republic of China; 3Department of Physiology, Shihezi University School of Medicine, Shihezi, 832003, People’s Republic of China; 4Department of Pathophysiology, Shihezi University School of Medicine, Shihezi, 832003, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ketao Ma; Yanming Wang, Department of Physiology, Shihezi University School of Medicine, Shihezi, 832003, People’s Republic of China, Tel +86 150 0164 5180 ; +86 175 9093 3308, Email maketao@hotmail.com; wangyanminglyo@163.comPurpose: Esophageal squamous cell carcinoma (ESCC) is the most common malignant tumor of the upper gastrointestinal tract, characterized by high mortality and poor prognosis. …”
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A novel SCN5A variant causing Brugada syndrome: a case of Slovenian family by Karin Writzl, Tadej Žlahtič, Maruša Debeljak, Mirko Topalović, Martin Rauber, Bor Antolič, Anja Zupan Mežnar, Luka Klemen, Andrej Pernat, David Žižek, Matjaž Šinkovec

“…Documented ventricular arrhythmic events, sudden unexpected death in family members, accurate evaluation of Brugada signs and arrhythmic syncope, and genotyping of SCN5A for cardiac fast sodium channel Nav1.5, are the most important steps in diagnostic and prognostic evaluation. …”
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Deficit irrigation and biostimulation preconditioning to improve drought resistance in melon by Susana Zapata-García, Abdelmalek Temnani, Pablo Berríos, Pedro J. Espinosa, Claudia Monllor, Alejandro Pérez-Pastor

“…Four treatments were evaluated: (i) a farmer treatment, irrigated at 100 % ETc, (ii) a precision irrigation (PI) treatment, irrigated with a threshold of 20 % soil water depletion in the active root uptake zone, between flowering and ripening, otherwise irrigated as FARM; (iii) an irrigation suppression (IS) treatment, irrigated as PI for the most of the cycle, except between 42 and 55 days after transplant (swelling of the first fruits), when irrigation was totally suppressed; (iv) a biostimulated irrigation suppression treatment (ISb), irrigated as IS with two applications of biostimulant during vegetative development. …”
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Prenatal diagnostic accuracy and epidemiology of congenital lung malformations: A retrospective review of cases in a tertiary referral center in northern Finland in 2010–2020 by Topias Puumalainen, Tuomas Kauppinen, Hilkka Nikkinen

“…Conclusions We found that all CLMs were detected prenatally, but almost half of the prenatal diagnoses were inaccurate compared to postnatal diagnoses. Most lesions were diagnosed prenatally as CPAM, but postnatally many of them turned out to be BPS, hybrid CPAM/BPS, or CLO. …”
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REST: a preoperative tailored sleep intervention for patients undergoing total knee replacement – feasibility study for a randomised controlled trial by Simon White, Rachael Gooberman-Hill, Emma Johnson, Joel Glynn, Vikki Wylde, Chris Penfold, Katie Whale, Nicholas Howells, Ashley Blom, Amanda Burston, Wendy Bertram, Dane Rayment

“…Interviews indicated that most participants found the study processes and intervention acceptable.Conclusions This feasibility study has demonstrated that with some amendments to processes and design, an RCT to evaluate the clinical and cost-effectiveness of the REST intervention is feasible.Trial registration number ISRCTN14233189.…”
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Using the Community Perception Tracker (CPT) to inform COVID-19 response in Lebanon and Zimbabwe: a qualitative methods evaluation by Fiona Majorin, Anika Jain, Christine Haddad, Eddington Zinyandu, Ghassan Gharzeddine, Mutsawashe Chitando, Aline Maalouf, Ntandoyenkosi Sithole, Rita Doumit, Raissa Azzalini, Thomas Heath, Janet Seeley, Sian White

“…Outbreak-affected populations exposed to the programmes reported high levels of knowledge about COVID-19 and reported they practiced preventative behaviours, although this waned with time. Most population members also felt the COVID-19 programmes were relevant to their needs and said that non-government organisations were a trusted source of information. …”
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Community Structure and Succession Regulation of Fungal Consortia in the Lignocellulose-Degrading Process on Natural Biomass by Baoyu Tian, Chunxiang Wang, Ruirui Lv, Junxiong Zhou, Xin Li, Yi Zheng, Xiangyu Jin, Mengli Wang, Yongxia Ye, Xinyi Huang, Ping Liu

“…With the degradation of lignocellulose, fungal groups Mucoromycotina and Ascomycota decreased gradually, and wood-rotting fungi Basidiomycota increased and replaced the opportunist fungi to become predominant group. Most of the fungal clones identified in sample were related to the reported lignocellulose-decomposing strains. …”
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Resistance of spring bread wheat cultivars and lines to Septoria leaf blotch, tan spot, and spot blotch pathogens by Yu. V. Zeleneva, V. P. Sudnikovа, N. M. Kovalenkо, I. V. Gusev

“…Leaf and stem diseases of cereal crops are among the most harmful in the agrocenoses of Tambov Province, significantly reducing grain yield and rapidly progressing in many regions of Russia. …”
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Central Cluster Galaxies: A Hot Spot for Detectable Gravitational Waves from Black Hole Mergers by Yihao Zhou, Tiziana Di Matteo, Nianyi Chen, Luke Zoltan Kelley, Laura Blecha, Yueying Ni, Simeon Bird, Yanhui Yang, Rupert Croft

“…We evolve MBH binaries, simulate their GW emissions, and calculate their detection probability (DP) for PTAs. The most detectable CW sources are produced by MBH mergers with masses M _BH  > 10 ^10 M _⊙ in the lowest-frequency bins with f  < 10 nHz. …”
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Categorical classification of skin cancer using a weighted ensemble of transfer learning with test time augmentation by Aliyu Tetengi Ibrahim, Mohammed Abdullahi, Armand Florentin Donfack Kana, Mohammed Tukur Mohammed, Ibrahim Hayatu Hassan

“…Skin cancer is the abnormal development of cells on the surface of the skin and is one of the most fatal diseases in humans. It usually appears in locations that are exposed to the sun, but can also appear in areas that are not regularly exposed to the sun. …”
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Machine Learning Model for Predicting Pathological Invasiveness of Pulmonary Ground‐Glass Nodules Based on AI‐Extracted Radiomic Features by Guozhen Yang, Yuanheng Huang, Huiguo Chen, Weibin Wu, Yonghui Wu, Kai Zhang, Xiaojun Li, Jiannan Xu, Jian Zhang

“…SHAP analysis identified median CT value and skewness as the most influential predictors. Conclusion This study presents a simplified ML model using AI‐extracted radiomic features, which has strong predictive performance and biological interpretability for preoperative risk stratification of GGNs. …”
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Oral Manifestations in Menopause—A Scoping Review by Anca Labunet, Adriana Objelean, Andreea Kui, Laura Rusu, Alexandra Vigu, Sorina Sava

“…<i>Results</i>: A total of 30 studies were covered; 8 focused on salivary alterations, 5 on periodontal issues, 7 on bone, 3 on the microbiome, and 7 on multiple oral problems, showing that xerostomia and altered taste are the most common oral manifestations, followed by indirect causal effects on periodontitis. …”
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Acute Inflammatory Demyelinating Polyneuropathy: a comprehensive literature review by Karolina Serwońska, Artur Pastuszka, Jan Węgrzyn, Łukasz Fijałkowski, Aleksandra Nosal, Adam Czarnecki, Aleksandra Galanty-Ochyra, Piotr Zając Zając, Olga Jabłońska

“…While immunotherapy significantly improves recovery, challenges persist, particularly in the most severe cases. Further research into pathophysiological mechanisms and experimental therapies is essential to refine treatment approaches and improve patient outcomes. …”
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A full-length 16S survey using Nanopore sequencing to uncover the bacterial microbiome in Ixodes ricinus ticks from a single UK woodland, collected across three springs (2019-2021) by Mia L. White, Jack M. Crook, Kayleigh M. Hansford, Daniel P. Carter, Michael J. Elmore, Colin Johnston, Sara Gandy, Kuiama Lewandowski, Alexander Vaux, Karen L. Osman, Richard Vipond, Jolyon M. Medlock, Edward J Feil, Steven T. Pullan

“…Our results showed significant microbiome differences across life stages, but not by woodland type or year. Rickettsia was the most abundant taxon, with prevalence varying by life stage and year. …”
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