Parenteral and Oral Anticoagulant Treatment for Hospitalized and Post-Discharge COVID-19 Patients: A Systematic Review and Meta-Analysis by Rahajeng N Tunjungputri, Erpryta N Tetrasiwi, Nadia A Mulansari, Kuntjoro Harimurti, Erni J Nelwan

“…This systematic review and meta-analysis aims to provide the most recent update on available evidence on the clinical benefits and risk of oral and parenteral anticoagulants, as well agents with anticoagulant properties, in hospitalized and post-discharge COVID-19 patients. …”
Get full text

Investigating the effects of a novel gamified cognitive training on adolescent mental health by Karina Grunewald, Savannah Minihan, Jack L. Andrews, Annabel Songco, Sarah-Jayne Blakemore, Anson Kai Chun Chau, Jaimee Fischer, Elaine Fox, Alba Bruggeman Nelissen, William Raffe, Matthew Richards, Aliza Werner-Seidler, Susanne Schweizer

“…Conclusions As engagement is often the most difficult thing to achieve in cognitive training with adolescents, observing greater repeated engagement with the gamified cognitive training is promising, given training on these apps is entirely self-motivated. …”
Get full text

A cohort of mRNAs undergo high-stoichiometry NSUN6-mediated site-specific m5C modification by Yuan-Yuan Zhang, Cai-Tao Li, You-Jia Zhou, Hao Li, Jing Li, Qing-Ping Xiong, Wei Zhou, Wenze Huang, Qiangfeng Cliff Zhang, Yangfei Xiang, En-Duo Wang, Beisi Xu, Ru-Juan Liu

“…Beyond N6-methyladenosine (m6A), most other internal mRNA modifications lack dedicated catalytic machinery and are typically introduced by tRNA-modifying enzymes. …”
Get full text

Effect of Nationwide Postoperative Rehabilitation at Home Program after Lower Extremity Surgeries in Older and Younger People by Kyunghoon Min, Sangchul Lee, Jae Min Kim, Jung Hyun Park, Jun Hwan Choi, Bo Ryun Kim, Kyu Wan Kwak, Seong Jun Kim, Jae-Young Lim

“…Results Participants were categorized into OG (n=801) and YG (n=71). The most common surgeries were knee joint replacement (63.7%) in OG and hip joint replacement in YG (77.5%). …”
Get full text

Evaluation of our care model in patients with fragility hip fracture: Multidisciplinary team and Fracture Liaison Service. A three-year retrospective study by José S. Barreda-Puchades, Joan Andreu-Safont, Sara Linares-Aguayo, Rafael Ortiz-Ramón, Marta Ribelles-Férez, Alberto García-Roig, Pablo Cañete-Sanpastor

“…Results: The mean age was 85,21 ± 6,87 years, with 183 women (76, 25 %) and 57 men (23,75 %). The most frequent fracture was pertrochanteric, with 111 (46.25 %) cases. …”
Get full text

Plasma cell-free extrachromosomal circular DNA is a molecular hallmark of preeclampsia by Peng Han, Chunxiao Zhang, Fangfang Ge, Chengxun Liu, Jing Fu, Wei Lv, Xin Jin, Jianguo Zhang, Lijian Zhao, Yonglun Luo, Xi Su, Xinqiang Lan

“…Statistically, COMT-containing eccDNA was the most abundant and recurrent in PE. Among the 14 paired plasma samples from pre-diagnosis and diagnosed PE cases, we observed a significant increase in eccDNA abundance in PE (p = 4.14 × 10−10), with 7 of the 9 gene-carrying eccDNAs uniquely identified in PE plasma. …”
Get full text

Identification of water deficit stress tolerant genotypes of common bean using adaptive root and shoot traits under different screening systems by Ishrat Riyaz, Aaqif Zaffar, Samreen Fatima, Sadiah Shafi, Rayan Bhat, Sanifa Showkat, Tamana Khan, Fehim J. Wani, Sajad Majeed Zargar, P. V. Vara Prasad, Parvaze A. Sofi

“…Genotypes WB-216 and N-2 were superior for most of the traits with adaptive plasticity response to water deficit stress and can be used for development of climate resilient bean varieties.…”
Get full text

Association Between Chronic Pain, Coping Strategies, and Sleep Quality in Rural Chinese Older Adults: A Cross-Sectional Study by Tao X, Cheng C, Bai J

“…Descriptive statistics, Pearson correlation, Stepwise multiple linear regression, and mediation analysis were used to analyze the data.Results: A total of 158 participants (48.7% female) were included in the study. Most participants (73.4%, n = 116) reported poor sleep quality. …”
Get full text

Adaptation of J-SPEED for the emergency department of a regional hospital in the Republic of Uzbekistan: retrospective analysis by Olimjan Nazirkulov, Odgerel Chimed-Ochir, Yui Yumiya, Inn Kynn Khaing, Khasanjon Odilov, Hanako Ogawa, Ami Fukunaga, Khalilov Kobiljon, Mahamadjan Mirzahmedov, Sukurullaxon Fayzullaxonov, Khikmat Anvarov, Mutalov Boburjon, Ruzimurodov Nodirjon, Tatsuhiko Kubo

“…Among non-trauma patients, hypertension (26%), neurological diseases (18.78%), and gastrointestinal diseases (10.48%) were the most common health events. Trauma incidents peaked from July to October. …”
Get full text

TMEM160 inhibits KEAP1 to suppress ferroptosis and induce chemoresistance in gastric cancer by Chunye Huang, Qinru Zeng, Jingyi Chen, Qin Wen, Weilun Jin, Xiaofeng Dai, Ruiwen Ruan, Hongguang Zhong, Yang Xia, Zhipeng Wu, Ruixuan Huang, Jianxi Zhang, Yangyang Yao, Li Li, Wan Lei, Jianping Xiong, Jun Deng

“…Abstract Chemoresistance is the most significant challenge affecting the clinical efficacy of the treatment of patients with gastric cancer (GC). …”
Get full text

Barriers and facilitators to accessing healthcare for early diagnosis of prostate cancer for black men—a qualitative exploration in North-East England and Scotland by Floor Christie-de Jong, Olugbenga Samuel Oyeniyi, Lawrence Achilles Nnyanzi, Jonathan Ling, Marie K. Murphy, Judith Eberhardt, Rawand Jarrar, John Kabuye, Martin Kalemba, Kathryn A. Robb

“…Abstract Introduction Prostate cancer is the most commonly diagnosed cancer in men in the United Kingdom. …”
Get full text

DIDACTIC POTENTIAL OF MOBILE APPLICATIONS FOR LEARNING ENGLISH AS A FOREIGN LANGUAGE by Blynova Neliia, Kyrylova Oksana, Dolzhenko Maryna

“…Application developers pay the most attention to grammatical material and thematic vocabulary. …”
Get full text

Examining the overlap in lymphatic filariasis prevalence and malaria insecticide-treated net access-use in endemic Africa. by Joanna L Whisnant, Mustafa Kamal Sikder, Gizachew Taddesse Akalu, Tsegaye Alemu, Mubarek Yesse Ashemo, Amelia Bertozzi-Villa, Annie J Browne, Ewerton Cousin, Paulina Agnieszka Dzianach, Yalemzewod Assefa Gelaw, Peter W Gething, Taren M Gorman, Simon I Hay, Olayinka Stephen Ilesanmi, Cathleen Keller, Juniper Boroka Kiss, Jailos Lubinda, Michael A McPhail, Olivia D Nesbit, Gideon Olamilekan Oluwatunase, Verner N Orish, Amel Ouyahia, Susan Fred Rumisha, Adam Saddler, Afeez Abolarinwa Salami, Francesca Sanna, Desalegn Shiferaw, Jacques Lukenze Tamuzi, Daniel J Weiss, Naod Gebrekrstos Zeru, Francis Zeukeng, Stephanie R M Zimsen, Jonathan F Mosser

“…In this analysis, ITN coverage was low in areas where LF is common, with 51.7% (90/174) of high-LF-prevalence-IUs having both access and use estimates under 40%. Most (67.8%; 61/90) of these low-ITN-coverage, high-LF-prevalence locations were also categorized as high- or highest-prevalence for malaria by PfPR, suggesting suboptimal ITN coverage even in some malaria-co-endemic locations. …”
Get full text

Food and drink advertising along school children’s transport routes in Victoria, Australia and policy implications by Sherly X Li, Claire Hardi, Rebecca Godwin, Rachael Jinnette, Belinda Morley, Helen Dixon, Jane Martin

“…Of these, almost six in ten (58 %) were deemed unhealthy irrespective of SEA or regionality. Marketing appeals most featured were taste (31 %), convenience (28 %) and emotion (9 %). …”
Get full text

Clinical characteristics and survival outcomes in patients with primary ovarian carcinoid: A historical cohort study by Shujun Kong, Jianan Sun, Xiaolong Sui, Shuaizhi Zhang, YuanBao Qi, Yuanxu Ma, Sijian Li

“…Pathological analysis showed that strumal carcinoid was the most predominant subtype, occurring in 66.1% of the patients. …”
Get full text

Evaluation of Intrarow Spacing on Growth and Yield Performance of Four Onion (Allium cepa L.) Varieties in Beyeda District, North Gondar, Ethiopia by Wubetie Adnew Wassie, Gashaw Fenta Assegahegn, Berhanu Abraha Tsegaye, Amare Bitew Mekonnen

“…Intrarow spacing showed a significant effect on onion growth and bulb yield parameters, as the earliest (135 days) and the most delayed (146 days) maturity were recorded at 6 cm and at 12 cm spaces, respectively. …”
Get full text

Electrocardiographic abnormalities in Chagas disease in the general population: A systematic review and meta-analysis. by Lyda Z Rojas, Marija Glisic, Laura Pletsch-Borba, Luis E Echeverría, Wichor M Bramer, Arjola Bano, Najada Stringa, Asija Zaciragic, Bledar Kraja, Eralda Asllanaj, Rajiv Chowdhury, Carlos A Morillo, Oscar L Rueda-Ochoa, Oscar H Franco, Taulant Muka

“…This research of observational studies indicates a significant excess in prevalence of ECG abnormalities (40.1%) related to T. cruzi infection in the general population from Chagas endemic regions, being the most common ventricular (RBBB and LAFB), and A-V B (first-degree) node conduction abnormalities as well as arrhythmias (AF or flutter and VE). …”
Get full text

Snapshot of Obstetric National Audit and Research Project (SONAR1): aprotocol for an international observational cohort study by S Ramani Moonesinghe, Bo Hou, Brendan Carvalho, Samantha Hill, Pervez Sultan, Susanna Stanford, Nuala Lucas, James O’Carroll, Reshma Patel, Justin Kua, Nadir El Sharawi, Victoria Eley, Pat O’Brien, Robert Craig

“…Introduction Caesarean birth (CB) under neuraxial anaesthesia (NA) is the most performed inpatient operation in the UK. The incidence of intraoperative pain during caesarean delivery performed under neuraxial anaesthesia is unclear, with limited data that used patient-reported measures to investigate intraoperative pain. …”
Get full text

Klebsiella pneumoniae with capsule type K64 is overrepresented among invasive disease in Vietnam [version 2; peer review: 1 approved, 2 approved with reservations, 1 not approved] by Bich Vu Thi Ngoc, Kathryn E Holt, Dung Vu Tien Viet, Trinh Dao Tuyet, Sylvain Brisse, Heiman F L Wertheim, Diep Nguyen Thi Ngoc, Huong Tran Thi Kieu, Trung Nguyen Vu, H Rogier van Doorn

“…Antibiotic susceptibility testing was performed using disk diffusion. Results The most common detected capsule types were K1 (39/203, 19.2%, mainly ST23) and K2 (31/203, 15.3%, multiple STs: ST65, ST86, ST380). …”
Get full text

THE USE OF INFORMATION TECHNOLOGIES IN THE SPECIALIZED TRAINING OF STUDENTS OF ENGINEERING AND PEDAGOGICAL SPECIALTIES by Tsys Oleh, Arkhypov Ihor

“…Ways to eliminate the shortcomings of traditional approaches to the study of specialized courses are proposed, one of which is the development and implementation of e-courses on the Moodle platform, since this platform allows combining different formats of information, makes it possible to timely update the educational material in accordance with the pace of development of the transport industry, as well as it is easy to use and supported by most modern Smart devices. The structural and functional components of the e-learning course are defined including an information and organizational component; a training component; an information and reference component; and a practical component. …”
Get full text