Brain-wide input-output analysis of tuberal nucleus somatostatin neurons reveals hierarchical circuits for orchestrating feeding behavior by Esra Senol, Menghan Wang, Yongjuan Xin, Zhuolei Jiao, Hasan Mohammad, Xin Yi Yeo, Tengxiao Si, David M. Young, Hua Huang, Yingxue Wang, Qin Li, Sang Yong Jung, Xiaohong Xu, Pei Zhang, Yu Fu

“…To gain a deeper understanding of the TNSST neural networks, we quantitatively characterised the brain-wide input-output configuration of mice TNSST neurons using the VITALISTIC method (Viral Tracing Assisted by Light-Sheet microscope and Tissue Clearing) and single-cell projectomes by fluorescence micro-optical sectioning tomography (fMOST). We found that TNSST neurons receive direct inputs from and send outputs to a broad range of brain regions, including many cortical and subcortical areas. …”
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The influence of physical activity, sedentary behavior on health-related quality of life among the general population of children and adolescents: A systematic review. by Xiu Yun Wu, Li Hui Han, Jian Hua Zhang, Sheng Luo, Jin Wei Hu, Kui Sun

“…<h4>Background</h4>The association between physical activity, sedentary behavior and health-related quality of life in children and adolescents has been mostly investigated in those young people with chronic disease conditions. …”
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Network meta-analysis on the efficacy of different interventions for treating thin endometrium by Feng Keng, Wu Ling, Zhang Zhao, Luo Yudi, Li Xiang, Li Derong, Zhong Junjie, Lan Liuping, Zhu Lingling

“…Overall, PRP showed significant advantages in both increasing endometrial thickness and improving clinical pregnancy rates, making it the most promising intervention.ConclusionPRP demonstrates the best clinical application potential in treating thin endometrium, particularly in improving clinical pregnancy rates. …”
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Evaluation of the performance of radioprotection ionization chambers used in radiometric survey of radiology clinical systems by Ezequiel da Silva, Lucas Rodrigues Santos, Ladyjane Pereira Fontes Assemany, Maria da Penha Albuquerque Potiens

“…Radiation detectors are equipment used to measure the levels of radiation emitted by sources, be they natural or artificial. Among the most commonly used detectors are ionization chambers (IC). …”
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Global burden and trend of stroke attributable to metabolic risks among young adults (20–39 years old) from 1990 to 2021 by Qingguo Liu, Jiao Su, Yuanhao Liang, Xiaofeng He

“…Notably, the proportion of stroke-DALYs attributable to metabolic-risks showed a positive association with SDI and increased across all regions during the study period. The most notable increases were observed in Eastern Europe. …”
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Studies on temporal-spatial expression characters of Bt protein in two transgenic hybrid cotton by YU En, CAI Yunfei, ZHAO Rubing, CHEN Jinhong, ZHU Shuijin

“…Cotton bollworm, Helicoberpa armigera, was one of the most harmful pests in cotton-production areas all over the world. …”
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Patterns of claims and determinants of claim rejections in Kuwait's National Health Insurance for Retirees (AFYA): a comprehensive analysis by Abdullah I. Alibrahim, Abdullah I. Alibrahim, Abdullah I. Alibrahim, Abdullah I. Alibrahim, Hisham Kelendar, Abdulaziz Alhenaidi

“…Rejection rates gradually declined over time, from 4.15% in 2017 to 3.42% by 2023. The most frequent reasons for denial involved uncovered services and insufficient clinical justification.DiscussionThese findings underscore the critical role of clear coverage definitions, consistent coding, and effective administrative oversight in minimizing denials. …”
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Circulation of Fungi of the Genus Candida in Children's and Adult Multi Purpose Hospitals by M. I. Petrukhina, A. M. Martynova2, N. G. Politova, N. V. Starostina, A. N. Cairo

“…In both children's and adult hospitals, the most common Candida fungi have been isolated from the Department of Resuscitation and Intensive Care patients mainly from sputum and urine, less often from blood, separated wounds, abdominal cavity and from cerebrospinal fluid (only in children). …”
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Residue Elimination Patterns and Determination of the Withdrawal Times of Seven Antibiotics in Taihang Chickens by Huan Chen, Cheng Zhang, Nana Gao, Guohua Yan, Yandong Li, Xuejing Wang, Liyong Wu, Heping Bai, Hongyu Ge, Huage Liu, Juxiang Liu

“…At 4 h after drug withdrawal, the drug residues in various tissues reached their highest values. In most cases, the drug concentrations in the kidney and liver were higher than those in the muscles and sebum; however, some drugs also exhibited concentration peaks in the sebum. …”
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Aggressiveness Traits as Predictive Factors for the Components of the Wellbeing of Young People by Artur A. Rean, Andrey O. Shevchenko, Alexey A. Stavtsev, Ivan A. Konovalov, Roman G. Kuzmin

“…Aggression and aggressiveness as properties of personality are certainly among the most destructive phenomena. As young people are an important social group in the structure of society, the direction of development greatly depends on them. …”
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MPFL reconstruction vs. Insall procedure for adolescent patellar instability: nine-year follow-up on osteoarthritis, redislocations, and return to sports by Maija Jääskelä, Marja Perhomaa, Lasse Lempainen, Jaakko Sinikumpu

“…Of the 129 patients, 31 met the inclusion criteria, and 24 patients (25 knees; 77%) participated in long-term clinical and radiographic follow-up. Most patients were female (62%) with a mean surgery age of 14.5 ± 1.3 years. …”
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Microbial community shifts drive biodegradable microplastic inhibition of seed germination in plateau wetlands by Hong Xiang, Jia-Xian Luo, Hao-Ran Bao, Xiao-Long Sun, Hao-Qin Xiong

“…The findings revealed that the group treated with biodegradable MPs (polybutylene succinate-PBS) exhibited the most potent inhibition of seed germination. Specifically, treatments with polyethylene-PE yielded a minimum of 54 seedlings, contrasting sharply with the PBS group, which produced only 24 seedlings under comparable conditions. …”
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Thrombocytopenia as a Side Effect of Heparin Therapy and COVID-19 Vaccination: A Review by S. S. Postnikov, N. V. Teplova, O. V. Gulbekova

“…This study aimed to conduct a comparative analysis of HIT and VITT prevalence, pathogenetic mechanisms, clinical manifestation patterns, and treatment considerations in order to select the most effective therapeutic strategies for each condition and optimise them for clinical use.DISCUSSION. …”
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Digitising wound care: a cost-consequence analysis of the Wound Care Command Centre™ in Australia by Michelle Barakat-Johnson, Meg Newton, Crispin Cayley, Michelle Lai, Laura Dixie, Nathaniel Alexander, Marc Pelusi, Jimmy Chan, Anna Cohen

“…Abstract Background Chronic wounds pose considerable financial challenges for healthcare systems globally, with most cases requiring hospital care and extended lengths of stay, particularly due to delayed access to treatment. …”
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Long-term efficacy and safety of artificial urinary sphincter AMS 800^ТМ implantations by E. I. Veliev, A. A. Tomilov, E. N. Golubtsova

“…Stress urinary incontinence in men in most cases occurs after radical prostatectomy or surgery of benign prostate hyperplasia. …”
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Cassiopeia A’s Reverse Shock and Its Effects on the Expanding SN Ejecta by Robert A. Fesen, Dan Milisavljevic, Daniel Patnaude, Roger A. Chevalier, John C. Raymond, McKinley Brumback, Kathryn E. Weil

“…Such ablated material is most prominently seen in higher ionization line emissions, whereas denser parts of ejecta knots show surprisingly little deceleration.…”
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Improving medication adherence to endocrine therapy in breast cancer patients: a mixed-methods systematic review of effective communication strategies for healthcare providers by M.A.A. Smits, L.H. Mammatas, L. Schoonhoven, S.C.J.M. Vervoort

“…Background: Breast cancer is the most common cancer in women worldwide. Adjuvant endocrine therapy (AET) improves survival, but adherence often declines, increasing mortality risk. …”
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Identifying liver cirrhosis in patients with chronic hepatitis B: an interpretable machine learning algorithm based on LSM by Xueting Bai, Chunwen Pu, Wenchong Zhen, Yushuang Huang, Qian Zhang, Zihan Li, Yixin Zhang, Rongxuan Xu, Zhihan Yao, Wei Wu, Mei Sun, Xiaofeng Li

“…The SHAP analysis indicated that LSM contributed the most to the model. The model still showed strong discriminative power when using only LSM or traditional indicators alone.Conclusions Machine learning models, especially the RF model, can effectively identify LC in CHB patients. …”
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Development of empirical anti-inflammatory diet index: a cross-sectional study by Joanna Kaluza, Lisa Hellerström, Daniel Kaluza, Abbas Chabok, Agneta Åkesson, Karl Michaëlsson, Alicja Wolk

“…The eADI was developed in a randomly chosen Discovery group (n = 2,216) using a 10-fold feature selection with filtering (based on Lasso regression) to select food groups most correlated with inflammatory biomarkers. From the selected foods, the eADI was then constructed based on summed scores of the consumption tertiles (corresponding to 0, 0.5, and 1 point). …”
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Surgical vs. Medical Management of Infective Endocarditis Following TAVR: A Systematic Review and Meta-Analysis by Dimitrios E. Magouliotis, Serge Sicouri, Massimo Baudo, Francesco Cabrucci, Yoshiyuki Yamashita, Basel Ramlawi

“…However, single-center outcomes demonstrated markedly improved survival with surgery (96% vs. 51%). The most common surgical indications included severe valvular dysfunction (50.3%), aortic root abscess (26.5%), and large vegetations (21.3%), in line with current guideline recommendations. …”
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