Global and regional disease burden of HIV/AIDS from 1990 to 2021 and projections to 2030 by Youwang Lu, Huiqin Li, Rongjing Dong, Mi Zhang, Xingqi Dong, Cuixian Yang, Xicheng Wang, Junchuan Ye

“…Burundi (EAPC 14.04%, 95% CI -13.63 to -14.44%), followed by Burkina Faso, exhibited the most significant decrease in the ASIR. Globally, the highest incidence rate was observed in the 25–29 years old group. …”
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Exploring Melasma Patients’ Needs Through Social Media: A Qualitative Study by Liu X, Liu X, Han Y, Cheng Y, Luo H, Liu Y, Li D, Guo W, Jiang H, Guo L, Jiang X

“…Treatment and prevention were the most discussed topics, with patients seeking information on effective, long-term, and affordable treatment. …”
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Interferon regulatory factor -9 in Labeo rohita, an insight into its interacting domain residues and dynamic responses to PAMPs stimulation and pathogenic challenges by Bristy Ganguly, Smruti Mahapatra, Saswati Pani, Rakesh Das, Ashis Saha, Mrinal Samanta

“…In-vitro and in-vivo stimulation with poly I: C or LPS significantly (p < 0.05) enhanced LrIRF9 gene expression in most of the examined tissues, RBCs, PBLs, and macrophages. …”
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Assessment of Treatment in Inflammatory Bowel Disease Patients Using Steroid Assessment Tool (SAT) in a Tertiary Center from Romania by Loredana GORAN, Lucian NEGREANU

“…Results: Results showed that most of our IBD patients (90%) had been treated with 5-ASA, with 29.2% of CD patients and 54.3% of UC patients currently using 5-ASA. …”
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Estimating diagnostic delay in patients with pituitary adenomas in Sweden: a cross-sectional study by Cecilia Follin, Oskar Ragnarsson, Maria Forsgren, Christina Dahlgren, Caroline Alkebro, Pia Burman, Per Dahlqvist, Charlotte Höbye, Margareta Lindgren, Helena Wik, Maria Wärn, Anna-Karin Åkerman, Britt Eden Engström, Bertil Ekman

“…A longer delay was observed in women compared with men (p&lt;0.001). The most frequent patient-reported symptoms among NFPA were headache and visual disturbances; for prolactinomas, menstrual irregularities and headache; for acromegaly, change in appearance and snoring; and for CD, weight gain and tiredness. …”
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Treatment success at the stage of obturation of root canal system by T. N. Manak, K. G. Kluiko, V. A. Mitronin

“…Relevance. In the most cases periapical pathology is caused by intra-canal infections and its initial treatment is by conventional endodontic treatment. …”
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Synergistic co-metabolism enhancing the crude oil degradation by Acinetobacter oleivorans DR1 and its metabolic potential by Lairenjam Paikhomba Singha, Renuka Kumari, Keisam Malabika Singha, Piyush Pandey, Pratyoosh Shukla

“…This repression reduces the activity of hydrocarbon-degrading bacteria, slowing down the rate of bioremediation. In this study, the most robust yet underexplored tool—liquid chromatography-high resolution accurate mass spectrometry system—was used to study the metabolic response and functional state of A. oleivorans DR1 during the crude oil degradation in the presence or absence of either biosurfactant or glucose supplementation. …”
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Acculturation and Plasma Fatty Acid Concentrations in Hispanic and Chinese-American Adults: The Multi-Ethnic Study of Atherosclerosis. by Cassandra S Diep, Rozenn N Lemaitre, Tzu-An Chen, Tom Baranowski, Pamela L Lutsey, Ani W Manichaikul, Stephen S Rich, David E St-Jules, Brian T Steffen, Michael Y Tsai, David S Siscovick, Alexis C Frazier-Wood

“…., with possible scores ranging from 0 (least acculturated) to 5 (most acculturated) points. α-Linolenic acid, linoleic acid, eicosapentaenoic acid, docosahexaenoic acid, and arachidonic acid were measured in fasting plasma. …”
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Comparison the Influence of Various Intensities of Aerobic Training on the Expression of RBL-1 and RB1 Genes in the Subcutaneous Adipose Tissue of Male Wistar Rats by Maryam Shavandi, Saeid Naghibi, Mohammad Shariatzadeh Joneydi, Maryam Vatandoust, Ali Zare

“…Background and Purpose: One of the most important methods to cope with obesity metabolic disorder is to do exercise activities that are both effective as a prevention and treatment. …”
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m6A methylation-mediated lncRNA RNF144A-AS1 promotes hepatocellular carcinoma progression through the miR-1301-3p/RNF38 pathway by Minyu Kong, Wendong Li, Hao Li, Yifan Jing, Min Xu, Yuting He, Wenzhi Guo

“…Abstract Background Globally, HCC is still one of the most common cancers. N6-methyladenosine (m6A) modifications and long-stranded noncoding RNAs (lncRNAs) play key roles in regulating HCC progression. …”
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Staging in the treatment of chronic calculous cholecystitis, complicated by choledocholithiasis by Alexander V. Smirnov, Vladimir R. Stankevich, Dmitry V. Sazonov, Artur R. Akhmedianov, Aishe A. Keshvedinova, Nikolay A. Solovyev, Yury V. Ivanov, Robert I. Khabazov

“…BACKGROUND: Chronic calculous cholecystitis is the most widespread disease in scheduled surgery departments, which in 10–15% of observations is complicated by choledocholithiasis. …”
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Key influencers in an aneurysmal thrombosis model: A sensitivity analysis and validation study by Qiongyao Liu, Toni Lassila, Fengming Lin, Michael MacRaild, Tufail Patankar, Fathallah Islim, Shuang Song, Huanming Xu, Xiang Chen, Zeike A. Taylor, Ali Sarrami-Foroushani, Alejandro F. Frangi

“…The sensitivity analysis of the thrombus composition indicates that the concentration of resting platelets most influences the final thrombus composition. Then, for the first time, we validate the thrombosis model based on a real patient case using patient-specific resting platelet concentration and two previously calibrated trigger thresholds for thrombosis initiation. …”
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Development, implementation, and evaluation of a rapid response system at a Nigerian teaching hospital, a novel idea in sub-Saharan Africa by Promise Ariyo, Seung W. Lee, Asad Latif, Chinyere Egbuta, Vinciya Pandian, Olufemi Bankole, Ibironke Desalu, John Sampson, Bradford Winters

“…The average time to arrival was 13 min. The most common trigger was altered mental status, followed by hypoxia and hypotension. …”
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Estimating the incidence of actionable drug-gene interactions in Japanese patients with major depressive disorder by Masakazu Hatano, Masashi Ikeda, Takeo Saito, Masami Miyata, Nakao Iwata, Shigeki Yamada

“…The incidence of actionable drug-gene interactions was estimated by multiplying the first-time prescription rate of each relevant antidepressant by the frequency of its corresponding actionable phenotype.ResultsA total of 3,197 patients were included in the analysis. Escitalopram was the most frequently prescribed antidepressant (18.7%, n = 597), followed by mirtazapine (17.5%, n = 561), and sertraline (15.4%, n = 493). …”
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Ethnobotanical study on factors influencing plant composition and traditional knowledge in homegardens of Laifeng Tujia ethnic communities, the hinterland of the Wuling mountain ar... by Shuwang Hou, Mengfan Yu, Zhen Yao

“…Homegarden plants, which are plants with specific functionalities that are either cultivated or consciously preserved within the homegarden, are the most critical elements of the homegarden and are capable of providing a multitude of products and services. …”
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Parents’ perspective on children’s access to healthcare services and associated factors: a cross-sectional study by Nona Salimi, Javad Javan-Noughabi, Vahid Ghavami, Reza Matinfar, Fatemeh Kokabisaghi

“…Data analysis was performed in STATA17 at a significant level of p < 0.05. Results Most study participants were women (n = 189, 60%) 31–40 years old (n = 132, 42%), had a high school degree (n = 198, 60.7%), 2–3 children (n = 158, 49.8%), average income (n = 126, 39.7%) and basic health insurance (n = 222,7%). …”
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THE ORIGIN OF THE HADITH ABOUT JAMPI-JAMPI: A Review of Harald Motzki's Isnad Cum Matan Analysis by Muhammad Syaiful, Mowafg Abrahem Masuwd

“…Motzki's approach helps to identify the historical layers in hadith transmission, confirming that most of the traditions about ruqyah have their transmission roots up to the generation of the tabi'in. …”
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Phytochemical Profile and Antioxidant Activities of Aqueous Extract of Moringa oleifera (Lam) Collected from DR Congo and Kenya by Valence Bwana Mutwedu, Albert Wafula Nyongesa, Jafred Mulama Kitaa, Jemima Achieng Oduma, James Mucunu Mbaria

“…Moringa oleifera Lam. is one of the most used plants in traditional medicine because of its high antioxidant properties. …”
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Herpes zoster incidence and burden in older Chinese: a systematic review and meta-analysis by Bingbing Zheng, Dapeng Yin, Yifan Geng, Qiao Li, Wenting Cao, Mingzhang Yin, Yi Ning, Jindong Ding Petersen

“…Neuralgia system disorders were the most frequently reported complications, followed by ear and eye diseases. …”
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CRIM-negative infantile Pompe disease, long-term observation of the effect of enzyme replacement therapy: a clinical case by D. R. Sabirova, D. I. Sadykova, A. A. Kucheryavaya, A. A. Kashina, L. A. Sabirova

“…In addition, CRIM (cross-reactive immunological material)-negative status determined immune tolerance therapy, including the most studied combination of three drugs: rituximab, methotrexate, and intravenous immunoglobulin, as a response to enzyme replacement therapy. …”
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