Extreme Elevations in Blood Pressure and All-Cause Mortality in a Referred CKD Population: Results from the CRISIS Study by James Ritchie, Francesco Rainone, Darren Green, Helen Alderson, Diana Chiu, Rachel Middleton, Donal O’Donoghue, Philip A. Kalra

“…This association was not seen in patients with baseline extreme hypertension and improved 12-month blood pressures (HR 0.86, P=0.5). Most CKD patients with extreme hypertension respond to pharmacological blood pressure control, reducing their risk for death. …”
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Reviewing Mangrove Degradation, Conservation, and Restoration: A Sustainability Nexus Assessment on Myanmar Using the DPSIR Framework by Lwin Thuzar Nyein, Daniel Karthe, Lukas Giessen, Mukand Singh Babel, Carsten Schusser

“…Further ground data measurements are still necessary to identify the primary factors causing mangrove degradation in Myanmar. The most commonly identified research methods were remote sensing methodologies while socio-political approaches were rarely considered in the context of mangrove preservation in Myanmar but are strongly needed in the future. …”
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Evolution of the Seismic Forecast System Implemented for the Vrancea Area (Romania) by Victorin-Emilian Toader, Constantin Ionescu, Iren-Adelina Moldovan, Alexandru Marmureanu, Iosif Lıngvay, Andrei Mihai

“…The primary monitored area is Vrancea, known for producing the most destructive earthquakes in Romania, with impacts extending to neighboring countries such as Bulgaria, Ukraine, and Moldova. …”
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Investigating Facilitators and Barriers in the Tendency of Older Adults to Third-Generation Universities by Sara Maghare Dehkordi, Samaneh Pourhadi, Masoud Lotfizadeh, Shima Sum

“…Objectives With the progress in the last century and the increased population of older adults, their social importance in society has become more prominent, and with the beginning of old age and retirement, most retired older adults face changes in different aspects of their lives. …”
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Randomized controlled trials – a matter of design by Spieth PM, Kubasch AS, Penzlin AI, Illigens BM, Barlinn K, Siepmann T

“…We performed a review of educational material, review articles, methodological studies, and published clinical trials using the databases MEDLINE, PubMed, and ClinicalTrials.gov. The most relevant recommendations regarding design, conduction, and reporting of RCTs may include the following: 1) clinically relevant end points should be defined a priori, and an unbiased analysis and report of the study results should be warranted, 2) both significant and nonsignificant results should be objectively reported and published, 3) structured study design and performance as indicated in the Consolidated Standards of Reporting Trials statement should be employed as well as registration in a public trial database, 4) potential conflicts of interest and funding sources should be disclaimed in study report or publication, and 5) in the comparison of experimental treatment with standard care, preplanned interim analyses during an ongoing RCT can aid in maintaining clinical equipoise by assessing benefit, harm, or futility, thus allowing decision on continuation or termination of the trial. …”
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Chronic S. mansoni infection critically regulates PbA infection-associated severity and pathological events in a mouse model by Andrew Kasiti Muganda, Edward Owiti Okonjo, James Nyabuga Nyariki, Dorcas Syokui Yole

“…Schistosomes which are blood flukes are the primary cause of schistosomiasis, which is the second most common parasitic illness in terms of morbidity and death after malaria. …”
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Insulin-like Growth Factor Administration Stimulates Wound Healing on Colonic Anastomosis in Hypoxic Rat Model by Khayal Al-Khayal, Alanoud Saad AlWesaimer, Maha Abdulla, Rehan Ahmad

“…Objective: Intestinal anastomosis is among the most commonly performed major abdominal procedures; however, leaks are an ongoing problem. …”
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A multimodal approach for enhanced disease management in cauliflower crops: integration of spectral sensors, machine learning models and targeted spraying technology by Rohit ANAND, Roaf Ahmad PARRAY, Indra MANI, Tapan Kumar KHURA, Harilal KUSHWAHA, Brij Bihari SHARMA, Susheel SARKAR, Samarth GODARA, Shideh MOJERLOU, Hasan MIRZAKHANINAFCHI

“…The spectral data sets were analyzed using decision tree and support vector machine (SVM) algorithms to identify the most accurate model for distinguishing diseased and healthy plants. …”
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CXCL10-dependent epithelial-vascular cross-talk for endothelial activation following SARS-CoV-2 infection by Chaillot Laura, Blondot Marie-Lise, Recordon-Pinson Patricia, Pellegrin Isabelle, Boizard-Moracchini Andrea, Sliusar Myroslava, Leboucq Teo, Pujol Nadege, Andreola Marie-Line, Bonnet Fabrice, Recher Gaelle, Andrique Laetitia, Nassoy Pierre, Mathivet Thomas, Bikfalvi Andreas

“…After infection of the epithelial cells, a significant inflammatory response was detected in the endothelial cells. CXCL10 was the most highly expressed proinflammatory cytokine involved in this intercellular communication, and its function was subsequently explored. …”
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Prevalence of Stroke and Associated Factors in a Middle-aged and Older Chinese Population: A Cross-sectional Study by Juan Guo, Qingmin Guo, Yuzhen Chen, Jinmei Zou, Hanjia Gao

“…The prevalence of stroke in middle-aged and older individuals in China was 2.170%. The most significant factors associated with stroke included smoking (odds ratio (OR): 1.471, 95% confidence interval (CI): 1.132–1.913), alcohol consumption (OR: 0.548, 95%CI: 0.405–0.743), nap time ≥30 min and <60 min (OR: 0.502, 95%CI: 0.296–0.851), nap time ≥60 min and <90 min (OR: 0.703, 95%CI: 0.505–0.978), hypertension (OR: 3.310, 95%CI: 2.515–4.357), dyslipidemia (OR: 1.874, 95%CI: 1.446–2.428), and diabetes (OR: 1.424, 95%CI: 1.052–1.927). …”
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Influence of virtual reality restorative environments on psychological well-being in university students: an evidence-based experimental study by Chengcheng Yin, Tongyu Li, Binxia Xue, Zirui Zhao

“…Virtual extraterrestrial space environments yielded the strongest improvements in attention and stress reduction, whereas mixed forest settings were most effective in decreasing negative affects. Structural equation modeling revealed that participants’ VRRE perceptions significantly influenced psychological recovery through seven of fifteen pathways. …”
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The Epidemiology of Hypertension in Uganda: Findings from the National Non-Communicable Diseases Risk Factor Survey. by David Guwatudde, Gerald Mutungi, Ronald Wesonga, Richard Kajjura, Hafisa Kasule, James Muwonge, Vincent Ssenono, Silver K Bahendeka

“…<h4>Background</h4>Hypertension is an important contributor to global burden of disease and mortality, and is a growing public health problem in sub-Saharan Africa. However, most sub-Saharan African countries lack detailed countrywide data on hypertension and other non-communicable diseases (NCD) risk factors that would provide benchmark information for design of appropriate interventions. …”
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Impact of cognitive decline on the physical functioning of older adults in Southern Brazil: a cross-sectional study by Andréa Kruger Gonçalves, Valéria Feijó Martins, Ana Carolina Kanitz, Flávia Gomes Martinez, Leonardo Alexandre Peyré-Tartaruga, Raphael Machado Castilhos, Aline Nogueira Haas, Aline Nogueira Haas

“…Statistical analyses included one-way ANOVA with post hoc Bonferroni tests.ResultsMost physical function variables worsened as cognitive impairment increased. …”
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Chinese dental students’ knowledge, attitudes, and practice regarding traumatic dental injuries in immature permanent teeth by Jingjing Yu, Chang Liu, Jian Yu

“…Participants had limited knowledge on correct emergency treatment for TDIs, including tooth replantation timing (51.6%), fixation method (43.8%), and time (25.5%), with 3rd -year undergraduates reporting the lowest percentage (10.2%) (p < 0.05). Most participants agreed that vital pulp preservation (95.0%) and additional examination (91.0%) are essential for TDI management. …”
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Dynamic identification of candidate genes associated with higher tocopherol biosynthesis in Brassica napus seeds by Yunyun Zhang, Yunyun Zhang, Ping Qin, Yajun Liu, Yingnan Liu, Wenjing Li, Chunjuan Luo, Peng Chen, Chunyu Zhang

“…(rapeseed) is recognized as the world’s second most important oilseed crop, serving as a primary source of vegetable oil and vitamin E. …”
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Evaluation of grain yield properties of wheat depending on long-term fertilization on vertisol soil by Terzić Dragan, Rajičić Vera, Babić Violeta, Luković Kristina, Tupajić Ivan, Šević Biljana, Stojiljković Jelena

“…Fertilization had the most significant impact on grain yield. Positive and highly significant correlations between yield and thousand grain weight were found in all investigated treatments, except for the control and the variant fertilized with 60 kg ha-1 of phosphorus, where significant correlations were found.…”
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Value-meaningful conceptualisation of educational material in the process of foreign language teaching at the university: A hermeneutic approach by O. A. Zheglova, A. F. Zakirova, L. V. Shilova

“…In the course of the final test of communicative and professional skills, most students demonstrated a confident command of the basics of professional communication in English. …”
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Engineering students' perceptions and actual use of AI-based math tools for solving mathematical problems by Kimberly F. Garcia, Ardvin Kester S. Ong, Ma. Janice J. Gumasing, Cesar Romeo V. Delos Reyes

“…The results revealed that hedonic motivation, perceived competence, performance expectancy, and habit are the most significant indicators of both students' behavioral intentions and actual use of AI-based math tools. …”
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Cestodes in Eurasian wolves (Canis lupus lupus) and domestic dogs (Canis lupus familiaris) in Switzerland by Anna Schneider, Gastón Moré, Mirjam Pewsner, Caroline F. Frey, Walter Basso

“…The flotation method thus failed to detect cestode infections in 44.7% (34/76) of infected wolves. The most frequently detected species was Taenia hydatigena (46/121; 38.0%), followed by Taenia serialis (23/121; 19.0%), Mesocestoides spp. (3/121; 2.5%), Taenia ovis (1/121; 0.8%), and Echinococcus multilocularis (1/121; 0.8%). …”
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Research on deep learning model for stock prediction by integrating frequency domain and time series features by Wenjie Sun, Jianhua Mei, Shengrui Liu, Chunhong Yuan, Jiaxuan Zhao

“…Abstract In the field of financial technology, stock prediction has become a popular research direction due to its high volatility and uncertainty. Most existing models can only process single temporal features, failing to capture multi-scale temporal patterns and latent cyclical components embedded in price fluctuations, while also neglecting the interactions between different stocks–resulting in predictions that lack accuracy and stability. …”
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