Synergistic antiproliferative and pro-apoptotic effects of Prunus armeniaca and bee venom on breast cancer cells by Sultan F. Kadasah, Abdulmajeed F. Alrefaei, Fahd Mohammed Abd Al Galil, Abdulaziz M.S. Alqahtani

“…IntroductionBreast cancer is the most prevalent malignancy among women worldwide, with triple-negative breast cancer (TNBC) posing significant therapeutic challenges due to its aggressive nature and lack of targeted treatments. …”
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Ameliorating Effect of Red Fruit (Pandanus conoides Lamk) Oil in Streptozotosin-Induced Diabetic Peripheral Neuropathy Rat Model: role of oxidative and neuroinflammatory pathways by Indah Tri Lestari, Kusnandar Anggadiredja, Afrillia Nuryanti Garmana, Ratna Annisa Utami

“…Objectives: Diabetic peripheral neuropathy (DPN) is the most common cause of neuropathy worldwide, with oxidative and inflammatory being the pathways involved in the disease pathology. …”
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Connection between trajectory of primary cancer monitoring indicators and mortality after cancer in South Korea by Jung Hyun Kim, Haedong Kim, Man S. Kim, Mison Chun, Jaeyong Shin

“…Results The study population comprised 294,070 cancer patients, with thyroid, stomach, colorectal, breast, and lung cancers being the most common. The prevention index (PI) levels, calculated from six primary prevention indicators, were categorized into High, Medium, and Low grades. …”
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Inter-seizure variability in thalamic recruitment and its implications for precision thalamic neuromodulation by Pariya Salami, Angelique C. Paulk, Daniel J. Soper, Pierre Bourdillon, Peter N. Hadar, Omar A. Alamoudi, Nathaniel D. Sisterson, R. Mark Richardson, Sandipan Pati, Sydney S. Cash

“…Results We show that seizures with <2 Hz synchronized-spiking patterns do not spread early to the thalamus, while seizures starting with faster activity (<20 Hz) spread early to all thalamic areas. Most importantly, seizures that begin broadly across the brain quickly recruit the centromedian and pulvinar areas, suggesting these may be better stimulation targets in such cases. …”
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Evaluating outcomes used in cardiothoracic surgery interventional research: a systematic review of reviews to develop a core outcome set. by Carina Benstoem, Ajay Moza, Rüdiger Autschbach, Christian Stoppe, Andreas Goetzenich

“…Measures of mortality, cerebrovascular complications and hospitalisation were reported most frequently. Two reviews chose a composite endpoint as primary outcome. …”
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Experimental usage of a multicomponent film in treatment of wounds by A. Yu. Grigoryan, A. I. Bezhin, T. A. Pankrusheva, B. S. Sukovatykh, M. S. Chekmareva, L. V. Zhilyaeva

“…Initially, high efficiency of the film was detected in vitro for the most common strains of test organisms, which werewound infection pathogens. …”
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Advancing thermal energy storage: Unravelling the optimal orientation of annular phase change material containers within the tank by Houssam Eddine Abdellatif, Ahmed Belaadi, Adeel Arshad, Boon Xian Chai, Ibrahim M.H. Alshaikh, Djamel Ghernaout

“…Model F, incorporating a rightward inclination of annular containers, emerges as the most efficient, boasting a remarkable 33.33 % reduction in melting time, concluding the melting process in a mere 1520 s. …”
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Quantitative Analysis of Isoflavones from <i>Fabaceae</i> Species and Their Chemopreventive Potential on Breast Cancer Cells by Wojciech Paździora, Karolina Grabowska, Paweł Zagrodzki, Paweł Paśko, Ewelina Prochownik, Irma Podolak, Agnieszka Galanty

“…<i>Genista tinctoria</i> showed the highest cytotoxicity against MCF7, while <i>Cytisus scoparius</i> and <i>Ononis arvensis</i> were most effective against MDA-MB-231 at a dose of 500 µg/mL. …”
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Continental hydroclimate during the late Paleocene-early Eocene in the central Rockies: insights from sedimentological and geochemical records preserved in the greater Green River... by Min Gao, Min Gao, Min Gao, Majie Fan, Guangsheng Zhuang, Domenico Chiarella

“…The late Paleocene to early Eocene (LPEE, ∼59–50 Ma) greenhouse condition is the most recent geologic analogue for future climate change induced by increased atmospheric CO2 partial pressure (pCO2). …”
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Determinants of certified seeds accessibility among farming households in Imo State, Nigeria by Njoku Loveday Chukwudi, Ominikari Godwin O., Umeh Ngozi Ekunyi, Nwabuisi Chibudo Joshua, Ebenehi Ojomugbokenyode, Musab Ibrahim, Ismail Ibrahim Hamma

“…Major challenges of accessing certified rice seeds indicated by the respondents include high cost of seeds (87.8%), lack of reliable certified seed (76.3%) and distance to source of purchase of certified seeds (44.4%). Most (62.6%) of the respondents have access to only one variety of certified rice seeds. …”
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Psychological distress and self-psychological adjustment methods of lung transplant recipients: an overview of systematic reviews by Shaobo Guo, Yingtian Jia, Ruiting Wang, Jing Sun, Hongxia Liu

“…The reporting assessment results showed that most of the included reviews still needed to be improved in terms of reporting quality. …”
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Assessment of water fluxes under the dual threat of changes in land cover and climate variability in the Brazilian Cerrado biome by Dimaghi Schwamback, Abderraman R. Amorim Brandão, Ronny Berndtsson, Edson Wendland, Magnus Persson

“…New hydrological insights for the region: We tested different parameter combinations during calibration and found that for sugarcane and pasture, saturated soil water content, parameter N in the soil retention function, and saturated hydraulic conductivity were the most sensitive ones to improve calibration. The validated models demonstrated good performance, with a mass balance error of less than 0.9 %. …”
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<p><strong>Alfalfa Responses to Drought, Salinity, and Herbivory by <em>Tetranychus urticae</em> (Acari: Tetranychidae) and Performance of the pest on Water-Stressed Plants</strong... by Samira Khodayari, Fatemeh Abedini

“…Drought and salinity stresses are the most serious induced problems of agriculture due to climatic changes. …”
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StreamSculptor: Hamiltonian Perturbation Theory for Stellar Streams in Flexible Potentials with Differentiable Simulations by Jacob Nibauer, Ana Bonaca, David N. Spergel, Adrian M. Price-Whelan, Jenny E. Greene, Nathaniel Starkman, Kathryn V. Johnston

“…Stellar streams are one of the most promising tracers of low-mass dark-matter subhalos. …”
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Exploring feasible factors to improve the practice of chronic kidney disease prevention among healthcare professionals in syria: a Q-methodology study by Fatema Ahmed, Qingyuan Ye, Li Li, Waleed Ksebe, Ruiyang Xu, Haya Radwan, Chen Wu, Kefang Wang

“…The eigenvalues of the first five factors are all greater than 1, and the cumulative explained variation is 80%. The most significant, amenable barriers were categorized into individual factors (‘lack of knowledge and awareness about risk factors and early detection among nursing staff, clinical guidelines and consulting among physicians’, ‘perceived challenging nature of CKD prevention for timely diagnosis and management preconditions among HCPs,’ and ‘perceived lack of adequate training among nurses’); interpersonal factors (‘poor communication between physicians and nephrologists’); and community/societal factors (‘lower apriority of CKD as a clinical issue,’ ‘lack of patient education resources about CKD prevention’, and ‘a fragmented healthcare system’). …”
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Case Report: Clinical features and management of anti-mGluR1 encephalitis: case illustration and review of the literature by Min Deng, Jing Xiong, Zhaohong Kong, Xufeng Wang, Tao Li

“…The prevalence was similar between men and women, with 50% of patients aged 40–59 years. The most common clinical manifestations were ataxia and dysarthria. …”
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Intraoperative low-dose esketamine on postoperative quality of recovery in patients undergoing open gynecologic surgery: a double-blinded, parallel-group, placebo- controlled trial by Zhi-Yu Geng, Yan Zhang, Xin Yan, Jun Hu, Ran Cui, Lin-Lin Song, Hui-Cheng Song

“…Future investigations are needed to determine the optimal dosing regimen and identify subgroups of gynecologic patients who would benefit most from esketamine.Trial registration Chinese Clinical Trial Registry; ChiCTR 2200061021.…”
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Robust hierarchical co-clustering for exploring toxicogenomic biomarkers and their chemical regulators by Mohammad Nazmol Hasan, Md Bahadur Badsha, Md. Nurul Haque Mollah

“…Abstract Toxicity measurement of doses of chemicals (DCs) is one of the most important tasks in toxicology studies and the drug discovery and development process. …”
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British Cardiovascular Intervention Society Consensus Position Statement on Out-of-hospital Cardiac Arrest 2: Post-discharge Rehabilitation by Marco Mion, Rupert Simpson, Tom Johnson, Valentino Oriolo, Ellie Gudde, Paul Rees, Tom Quinn, Johannes Von Vopelius-Feldt, Sean Gallagher, Abdul Mozid, Nick Curzen, John Davies, Paul Swindell, Nilesh Pareek, Thomas R Keeble

“…Accordingly, the British Cardiovascular Interventional Society established a multi-disciplinary working group to develop a position statement that summarises the most up-to-date evidence and provides guidance on essential and desirable services for a dedicated follow-up pathway for survivors of OHCA.…”
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Gemcitabine plus erlotinib for advanced pancreatic cancer: a systematic review with meta-analysis. by Zu-Yao Yang, Jin-Qiu Yuan, Meng-Yang Di, Da-Yong Zheng, Jin-Zhang Chen, Hong Ding, Xin-Yin Wu, Ya-Fang Huang, Chen Mao, Jin-Ling Tang

“…According to the studies with relevant data, the incidences of total and severe adverse events were 96.3% and 62.9%, respectively. The most frequently reported adverse events were leucopenia, rash, diarrhea, vomitting, neutropenia, thrombocytopenia, anaemia, stomatitis, drug-induced liver injury, fatigue and fever. …”
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