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82561
Antiseizure medication choice in diffuse glioma: A single‐center population‐based experience
Published 2025-06-01“…Forty‐nine (40.5%) had grade 2 glioma, 18 (14.9%) had grade 3 glioma, and 54 (44.6%) had grade 4 glioma. The most common first ASM was oxcarbazepine (39.2%), followed by levetiracetam (22.5%), carbamazepine (19.3%), phenytoin (10.8%) and valproic acid (8.3%). …”
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82562
ASAP1 Promotes Epithelial to Mesenchymal Transition by Activating the TGFβ Pathway in Papillary Thyroid Cancer
Published 2025-08-01“…ABSTRACT Background Papillary thyroid cancer (PTC) is the most common type of thyroid malignancy. While the prognosis of PTC is generally favorable, some cases exhibit aggressive behavior, leading to metastasis and recurrence. …”
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82563
Mutations in protocadherin 15 and cadherin 23 affect tip links and mechanotransduction in mammalian sensory hair cells.
Published 2011-04-01“…The av3J and v2J mice carry point mutations that are predicted to introduce premature stop codons in the transcripts for Pcdh15 and Cdh23, respectively, and av6J mice have an in-frame deletion predicted to remove most of the 9th cadherin ectodomain from PCDH15. …”
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82564
Shikonin inhibits NLRP3 inflammasome activation and controls inflammatory disease
Published 2025-05-01“…The NLRP3 inflammasome, one of the most studied inflammasomes, can cause uncontrolled inflammation and drive various diseases when dysregulated. …”
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82565
Driving forces of the spatiotemporal supply pattern of runoff in the source region of Yellow River
Published 2025-08-01“…New hydrological insights for the region: The results indicated that the monthly changes observed in stable isotopes across different waterbodies, along with their relation to the local meteoric water line, revealed that atmospheric precipitation contributed the most significantly to runoff in August. Contributions from precipitation, supra-permafrost water, and glacial snow meltwater to total runoff were 71, 24, and 5 %, respectively, at the river outlet. …”
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82566
Brain structural features with functional priori to classify Parkinson’s disease and multiple system atrophy using diagnostic MRI
Published 2025-07-01“…The positive and negative impacts of various features predicting PD and MSA were clarified, with larger fourth ventricular and smaller brainstem volumes being most significant. The proposed framework provides new insights into the comprehensive utilization of clinical 2D MRI images to explore underlying neuroimaging biomarkers that can distinguish between PD and MSA, highlighting disease-specific alterations in brain morphology observed in these conditions.…”
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82567
Low-dose interleukin 2 therapy halts the progression of post-streptococcal autoimmune complications in a rat model of rheumatic heart disease
Published 2025-04-01“…This is especially true in low-income countries and among Indigenous populations in high-income nations, where the disease burden is most severe. These conditions arise from an autoimmune response to group A Streptococcus infections, leading to long-term health complications, disability, and premature death. …”
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82568
Investigation of the Regularities of the Influence of Meteorological Factors on Avalanches in Eastern Kazakhstan
Published 2025-06-01“…Principal component analysis identified the most significant variables affecting avalanche activity, with temperature, snow cover height, and wind making the greatest contributions. …”
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82569
Oral nutritional supplements for gastric cancer – the review of current evidence
Published 2021-03-01“…After discharge from the hospital ONS can decelerate the progression of malnutrition, improve the tolerance of adjuvant chemotherapy and improve the quality of life. These effects are most clear after GE and in patients with a high risk of malnutrition (NRS‑2002 ≥ 3). …”
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82570
Silicone gel em cicatrizes de cirurgia plástica: estudo clínico prospectivo Silicone gel in plastic surgery scars: a prospective study
Published 2010-09-01“…Although the exact mechanism of action of silicone gel has not yet been elucidated, the most widely accepted theory explains that the occlusive film stimulates the keratinocytes to increase the local secretion of growth factors, subsequently influencing the regulation of fibroblasts. …”
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82571
Quantitative evaluation of thermal runaway in lithium-ion batteries under critical heating conditions to enhance safety
Published 2025-07-01“…Moreover, the study details the heat release dynamics of different chemical processes: the negative solvent contributed the most significant heat generation (1.78 kW), while the solid electrolyte interphase layer produced the lowest (0.133 kW). …”
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82572
The effect of daily physical activity on bidirectional transitions of elevated blood pressure status: the first longitudinal evidence from the CHARLS
Published 2025-06-01“…Conclusion Moderate intensity PA was most consistently associated with favorable transitions in elevated BP states. …”
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82573
Application of flexible parametric cure model in determination of effective factors on the technique of survival peritoneal dialysis patients in adults of Iran.
Published 2025-01-01“…<h4>Objective</h4>Peritoneal Dialysis (PD) is one of the most common methods of dialysis performed in patients with kidney failure. …”
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82574
Medial-Sided Repair in Multi-Ligamentous Knee Injury
Published 2024-06-01“…Background: Injuries to the medial structures of the knee are common in multi-ligamentous knee injuries (MLKIs), which account for 0.02% of orthopedic injuries each year. The most common medial structure involved is the superficial medial collateral ligament (sMCL) with possible additional injury to the posterior oblique ligament (POL) and deep medial collateral ligament (dMCL). …”
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82575
Model of a Parallel-Pipeline Computational Process for Solving a System of Grid Equations
Published 2023-09-01“…As a result of the research, a model of a parallel-pipeline computing process was developed using the example of one of the most time-consuming stages of solving a system of grid equations by a modified alternating-triangular iterative method. …”
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82576
Optimizing DSSCs Performance for Indoor Lighting: Matching Organic Dyes Absorption and Indoor Lamps Emission Profiles to Maximize Efficiency
Published 2025-07-01“…Among the various technologies available for obtaining energy in indoor conditions, Dye‐Sensitized Solar Cells (DSSCs) stand out as the most promising due to their ability to efficiently convert ambient light into usable electricity. …”
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82577
Can machine translation match human expertise? Quantifying the performance of large language models in the translation of patient-reported outcome measures (PROMs)
Published 2025-07-01“…Results In forward translations, the METEOR scores significantly varied depending on target languages for all MT tools (p < 0.001), with GPT-4 having the highest scores in most languages. We detected significantly different scores among translators for all languages (p < .05), except for Italian (p = 0.59). …”
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82578
Characterization of Java Island's volcanoes based on volcano density and quantification of volcanic products using Landsat imagery
Published 2025-08-01“…Java Island has 34 volcanoes that the twenty of them are the most active termed as type-A. The process of volcano generation and the characteristics of Java Island as part of the Sunda Arc produce Quarternary volcanoes from the western to the eastern land. …”
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82579
Photocatalytic CO2 Conversion with H2O to CO and CH4 Over V2C/TiO2 Composite
Published 2025-07-01“… Photocatalytic reduction of CO2 to valuable chemicals and fuels requires highly efficient semiconductor materials, and most available photocatalysts are less efficient. …”
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82580
Spontaneous Breakaway of Tractional Flap Tear during Acute Posterior Vitreous Detachment after Laser Retinopexy
Published 2022-10-01“…Flap tears in the peripheral retina are the most dangerous for the occurrence of regmatogenous retinal detachment (61–83 %), as they are always the result of dynamic vitreoretinal traction. …”
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