Cost-effectiveness of polatuzumab vedotin plus chemoimmunotherapy for untreated diffuse large B-cell lymphoma in China by Mengya Li, Qian Li, Yinhui Zhang, Changjing Xu, Zhu Chen, Yilan Huang, Longyang Jiang

“…One-way sensitivity analysis suggested that the model was most sensitive to the utility of PFS and the cost of polatuzumab vedotin. …”
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First contact: an interdisciplinary guide into decoding H5N1 influenza virus interactions with glycosaminoglycans in 3D respiratory cell models by Mariam Hassan, Bianca Kaifer, Tyra Christian, Xenia Tamara Quaas, Johannes Mueller, Heike Boehm

“…Among these, Influenza A viruses (IAVs) cause the most severe symptoms and course of disease. IAV has been a major health concern, especially since the emergence of the potentially pandemic avian H5N1 strain. …”
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Nitrate-nitrogen dynamics in response to forestry harvesting and climate variability: 4 years of UV nitrate sensor data in a shallow gravel aquifer by B. Wilkins, T. Johns, S. Mager

“…We found that there were two mechanisms of nitrate-nitrogen pulses in groundwater from the upgradient forestry land use, the most prevalent being nutrient loss during winter months, when plant uptake is lower. …”
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Topographic, anatomical and clinical rationale of the optimal minimally invasive technique of parathyroidectomy by P. N. Romashchenko, N. F. Fomin, D. O. Vshivtsev, N. A. Maistrenko, Yu. V. Maleev, D. S. Krivolapov, A. S. Pryadko, D. A. Starchik

“…The information presented in the literature on the use of minimally invasive interventions in the treatment of hyperparathyroidism is not fully justified by topographical and anatomical studies and does not take into account individual features of the location and syntopia of the parathyroid glands, which requires additional scientific research.Objective.Based on the topographical and anatomical features of the structure of the anterior neck region, we determined the most rational methods of minimally invasive interventions on the parathyroid glands and evaluated their clinical effectiveness in patients with hyperparathyroidism.Methods and materials. …”
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USP10 promotes the progression and attenuates gemcitabine chemotherapy sensitivity via stabilizing PLK1 in PDAC by Xuezhi Du, Runze Yu, Caigu Yan, Penggang Dong, Cheng Wei, Bo Wang, Chenhui Zhang, Yingjie He, Yaqing Wei, Lei Han, Jinjin Sun

“…Abstract Pancreatic ductal adenocarcinoma (PDAC) is one of the most malignant tumors with limited treatment options, and chemotherapy resistance contributes to poor prognosis. …”
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The Political Economy of Crisis and the Crisis of Political Economy: The Challenge of Sustainability by Graham Murdock

“…Yet communication systems, particularly digital systems, are central to the unfolding climate crisis, not simply as central spaces of public information (and misinformation) and debate, but as arrays of infrastructures and machines that consume resources and power and foster patterns of use and disposal that exacerbate problems of waste and pollution and reinforce patterns of inequality, with those least able to cope likely to be the most affected. The second part of the paper expands on this argument The third and final part follows the implications of this analysis through arguing that critical communications policy not only needs to address the problem of curbing corporate and state abuses of control and renew the project of building a non-marketised public communications system, it also needs to ensure that its interventions mitigate rather than exacerbate the problem of climate instability and address social inequalities. …”
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Automated detection of diabetic retinopathy lesions in ultra-widefield fundus images using an attention-augmented YOLOv8 framework by Lei-Si Hu, Jie Wang, Heng-Ming Zhang, Hai-Yu Huang

“…Among them, YOLOv8+ convSimAM achieved the most balanced and accurate results across multiple lesion types, demonstrating an enhanced capability to detect small, low-contrast, and structurally complex features. …”
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Rare, "Red Book" species of plants and animals in Baikal Siberia under CITES protection (in the context of sustainable development) by E. N. Yelaev, A. A. Alekseeva, A. A. Mokrov, N. G. Yelaeva

“…There are no protected species in the region from Annex III.An audit of the most vulnerable rare and Red Book species of plants and animals was carried out, as well as of the validity of including certain species in the Red Books (federal and regional) and the CITES List for the Biological Diversity Conservation and Sustainable Development of Baikal Siberia.…”
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Advanced Residual Optimal Mapping Approach for Precise Detection of Stator Faults in Induction Motors by Abderrahim Allal, Zakaria Lammouchi, Abderrahmane Khechekhouche, Naoui Mohamed, Khalid Alqunun, Amer Alghadhban, Ismail Marouani, Tawfik Guesmi

“…Experimental results indicate that TH appears to be the most sensitive harmonic for detecting stator faults, with a residual fault detection value of 4.5 A at full load and 5.05 A at half load. …”
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Analysis of TPACK (Technological Pedagogical Content Knowledge) ability Physical Education teacher’s by Faridha Nurhayati, Abdul Rachman Syam Tuasikal, Nurhasan Nurhasan, Heryanto Nur Muhammad, Dwi Cahyo Kartiko, Shoffurijal Agyanur, Adi Pranoto

“…Results: 1) Physical education teacher's TPACK ability for TK variables belongs to the moderate category (48.8%), PK belongs to the moderate category (59.7%), CK belongs to the moderate category (58.9%), TCK belongs to the good category (72.3%), TPK belongs to the moderate category (58.9%), PCK belongs to the good category (71.8%), and TPACK belongs to the moderate category (71.8%). 2) TPACK ability based on age, only the PK variable has significant differences and the PK ability is best at the age of 21- 40 years, while other variables have no significant difference. 3) TPACK ability based on educational units, from all educational units of each TPACK variable there is no significant difference. 4) TPACK ability based on service life, only the PK variable has a significant difference, with the best PK ability being in the working period of < 5 years, while the other variables do not have a significant difference, and 5) Analysis of factors that affect TPACK ability, age is the factor that most affects kindergarten ability, while for other variables each factor does not have a significant effect. …”
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PHUBBING BEHAVIOR AND SATISFACTION OF ROMANTIC RELATIONSHIPS IN EARLY ADULT DATING: A CORRELATIONAL STUDY by Kirey Febriani Ajooba, Krismi Diah Ambarwati

“…Conclusion: Phubbing behaviour is not related to romantic relationship satisfaction. Most respondents have phubbing behaviour and romantic relationship satisfaction at a moderate level. …”
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Serovars and antimicrobial resistance profiles of Actinobacillus pleuropneumoniae isolates from clinical-case pigs in Taiwan by Wei-Fan Kwan, Yanwen Li, Janine T. Bossé, Ming-Tang Chiou, Hsien-Jen Chiu, Paul R. Langford, Preben Mortensen, Chao-Nan Lin

“…Therefore serovar 15 was the most predominant between 2015 and 2022. Resistance of the isolates was minimal to ceftiofur (3.2%), cephalexin (5.2%), cephalothin (6.3%) and enrofloxacin (9.3%), moderate to gentamicin (28.4%), and high for florfenicol, amoxicillin and ampicillin (45.1–68.4%). …”
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High Burden and Trend in Nonadherence to Blood Pressure‐Lowering Medications: Meta‐Analysis of Data From Over 34 000 Adults With Hypertension in Sub‐Saharan Africa by Leopold N. Aminde, Valirie N. Agbor, Noah T. Fongwen, Calypse A. Ngwasiri, Clovis Nkoke, Miriam A. Nji, Anastase Dzudie, Aletta E. Schutte

“…Socioeconomic and patient‐related factors were the most frequent factors influencing adherence. Active patient participation in management, accurate perceptions, and knowledge of hypertension and its treatment predicted good medication adherence, whereas high pill burden, medication cost, side effects, and comorbidities predicted poor adherence. …”
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High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. by Lisa F Barcellos, Suzanne L May, Patricia P Ramsay, Hong L Quach, Julie A Lane, Joanne Nititham, Janelle A Noble, Kimberly E Taylor, Diana L Quach, Sharon A Chung, Jennifer A Kelly, Kathy L Moser, Timothy W Behrens, Michael F Seldin, Glenys Thomson, John B Harley, Patrick M Gaffney, Lindsey A Criswell

“…Single-marker analyses revealed strong signals for SNPs within several MHC regions, as well as with HLA-DRB1 (global p = 9.99 x 10(-16)). The most strongly associated DRB1 alleles were: *0301 (odds ratio, OR = 2.21, p = 2.53 x 10(-12)), *1401 (OR = 0.50, p = 0.0002), and *1501 (OR = 1.39, p = 0.0032). …”
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Reference equations for the six-minute walk distance in the healthy Chinese population aged 18-59 years. by He Zou, Xiuruo Zhu, Jia Zhang, Yi Wang, Xiaozhen Wu, Fang Liu, Xiaofeng Xie, Xiaoshu Chen

“…<h4>Conclusion</h4>In summary, age and height were the most significant predictors of the 6MWD, and regression equations could explain approximately 34% and 28% of the distance variance in the female and male groups, respectively.…”
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An update on crop-raiding by elephants at Bia Conservation Area, Ghana from 2004 to 2006 by Samuel Oppong, Emmanuel Danquah, Moses Sam

“…The southern portions of BCA were found to experience the most raids. The number of raids increased with the proximity of farms to the park boundary, types and the diversity of crops grown and size of farms. …”
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Prognostic significance of the logistic regression model for assessing the risk of recurrence in patients with prostate cancer after radical prostatectomy by S. A. Reva, A. V. Arnautov, O. A. Klitsenko, S. B. Petrov

“…The study’s objective is to investigate the influence of risk factors for recurrence of prostate cancer (PCa) after radical surgical treatment on the unfavourable course of recurrence of the disease with the formation of a set of the most significant factors of a model that reflects the likelihood of relapse.Materials and methods. …”
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Naringin Protects against Tau Hyperphosphorylation in Aβ25–35-Injured PC12 Cells through Modulation of ER, PI3K/AKT, and GSK-3β Signaling Pathways by Qi Qiu, Xia Lei, Yueying Wang, Hui Xiong, Yanming Xu, Huifeng Sun, Hongdan Xu, Ning Zhang

“…Alzheimer’s disease (AD) is the most common form of dementia and a significant social and economic burden. …”
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Effects of structured contraceptive counseling in young women: Secondary analyses of a cluster randomized controlled trial (the LOWE trial) by Karin Emtell Iwarsson, Volodymyr Podolskyi, Isabella Bizjak, Helena Kopp Kallner, Kristina Gemzell‐Danielsson, Niklas Envall

“…Long‐acting reversible contraception (LARC) are the most effective methods for preventing unwanted pregnancy, especially among young women. …”
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Sustained Long-Term Results with Minimal Reintervention Rates in Patients with Frozen Elephant Trunk and Acute Aortic Syndromes by Filippos-Paschalis Rorris, Christos F. Pitros, Constantine N. Antonopoulos, Konstantinos Papakonstantinou, Lydia Kokotsaki, Pantelis Tsipas, Ilias Gissis, John Kokotsakis

“…<b data-eusoft-scrollable-element="1">Results:</b> The mean patient age was 57.1 (±12.5) years, and the majority (20 patients, 87%) were male. The most common indication was Stanford type A acute aortic dissection (aTAAD) in 17 (74%) patients, followed by non-A non-B dissection in 2 (8.7%) patients, penetrating aortic ulcer (PAU) of the aortic arch in 2 (8.7%) patients, type A intramural hematoma (IMH) in 1 (4.3%) patient and blunt thoracic aortic injury of the aortic arch in 1 (4.3%) patient. …”
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