Performance of GPT-4 for automated prostate biopsy decision-making based on mpMRI: a multi-center evidence study by Ming-Jun Shi, Zhi-Xiang Wang, Shuang-Kun Wang, Xuan-Hao Li, Yan-Lin Zhang, Ying Yan, Ran An, Li-Ning Dong, Lei Qiu, Tian Tian, Jia-Xin Liu, Hong-Chen Song, Ya-Fan Wang, Che Deng, Zi-Bing Cao, Hong-Yin Wang, Zheng Wang, Wei Wei, Jian Song, Jian Lu, Xuan Wei, Zhen-Chang Wang

“…With the assistance of GPT-4, 20.8% (190/912) of the SOI population could avoid unnecessary biopsies, and it performed even better [28.8% (118/410)] in the most heterogeneous subgroup of PI-RADS score 3. More than 90.0% of GPT-4 -generated reports were comprehensive and easy to understand, but less satisfied with the accuracy (82.8%). …”
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Antimicrobial Resistance in ESKAPE Pathogens: A Retrospective Epidemiological Study at the University Hospital of Palermo, Italy by Luca Pipitò, Raffaella Rubino, Giulio D’Agati, Eleonora Bono, Chiara Vincenza Mazzola, Sofia Urso, Giuseppe Zinna, Salvatore Antonino Distefano, Alberto Firenze, Celestino Bonura, Giovanni M. Giammanco, Antonio Cascio

“…Results: A total of 11,607 specimens from 4916 patients were analyzed. Most patients were admitted to Internal Medicine (19.4%), the ICU (13.2%), and General Surgery (9.9%). …”
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Effectiveness and Safety of Immunotherapy for Hepatocellular Carcinoma in Clinical Practice: A Brazilian Multicenter Study by Leonardo Gomes da Fonseca, Cecília Souza Freire, Rodrigo Antonio Vieira Guedes, Marcos Castro Lyra, Maria Ignez Freitas Melro Braguiroli, Mariana Bruno Siqueira, Maria De Lourdes Lopes de Oliveira, Alexandre de Mendonça Palladino, Henry Luiz Najman, Rodrigo Tancredi, Duilio Reis Da Rocha Filho, Markus Cavalcante Gifoni, Guilherme Luiz Stelko Pereira, Marcela Crosara Alves Teixeira, Lucila Soares Da Silva Rocha, Raimundo Paraná, Paulo Marcelo Hoff

“…Immunotherapy was predominantly first-line (91.4%), with atezolizumab plus bevacizumab as the most common regimen (77.9%). The median treatment duration was 4.9 months, and the median overall survival (OS) was 14.7 months (95% CI, 11.6 to 24.5), with 12- and 24-month survival rates of 57.0% and 41.4%, respectively. …”
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Phaleria macrocarpa (Scheff.) Boerl. (Mahkota Dewa) seed essential oils: Extraction yield, volatile components, antibacterial, and antioxidant activities based on different solvent... by Dexter Ashley Jinoni, Mohammad Amil Zulhilmi Benjamin, Ahmad Asnawi Mus, Lucky Poh Wah Goh, Nor Azizun Rusdi, Mohd Azrie Awang

“…The essential oils from P. macrocarpa seeds demonstrates strong natural antibacterial and antioxidant potential, with hexane as the most efficient solvent. Exploring compounds like 1-(ethenylthio)-octane and 2,2-dimethyl-5-(3-methyl-2-oxiranyl)cyclohexanone may reveal medicinal applications and lead to innovative remedies.…”
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Cardiac Medication Prescription Pattern and Association With Transplant-free Survival in the Adult Fontan Population by Andrew M. Freddo, MD, PhD, Molly Eron, BS, Antara Mondal, MS, Alexis Z. Tomlinson, PhD, Srinivas Denduluri, PhD, Sara Partington, MD, Emily Ruckdeschel, MD, Allison L. Tsao, MD, Constantine D. Mavroudis, MD, MSc, MTR, Muhammad Nuri, MD, Stephanie Fuller, MD, MS, Juan M. Ortega-Legaspi, MD, PhD, Yuli Y. Kim, MD, Sumeet Vaikunth, MD, MEd

“…Results: There were 429 patients (55.2% male, 72.5% White, and 49.7% single left ventricle morphology) with median age 24 years (IQR: 22-29) at time of first clinic visit. The most prescribed medication classes were antiplatelet agents (74.6%) followed by angiotensin converting enzyme inhibitors or angiotensin receptor blockers (59.0%), anticoagulants (44.1%), loop diuretics (39.6%), metoprolol (32.2%), mineralocorticoid receptor antagonists (31.5%), antiarrhythmics (27.5%), and pulmonary vasodilators (16.1%). …”
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Physical health in young males and risk of chronic musculoskeletal, cardiovascular, and respiratory diseases by middle age: A population-based cohort study. by Aleksandra Turkiewicz, Karin Magnusson, Simon Timpka, Ali Kiadaliri, Andrea Dell'Isola, Martin Englund

“…No large consistent associations were found for other exposures. The most notable associations with specific musculoskeletal conditions were for cardiorespiratory fitness and osteoarthritis (RR 1.23 [95% CI 1.15, 1.32] per 1 SD) and for muscle strength and back pain (RR 1.18 [95% CI 1.12, 1.24] per 1 SD) or shoulder diseases (RR 1.27 [95% CI 1.19, 1.36] per 1 SD). …”
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Effects of salinity stress on morphological structure, physiology, and mRNA expression in different wheat (Triticum aestivum L.) cultivars by Xiaohui Sun, Xiaohui Sun, Yuliu Tan, Yuliu Tan, Yumei Zhang, Yumei Zhang, Weiwei Guo, Weiwei Guo, Ximei Li, Ximei Li, Nataliia Golub, Lili Zhang, Huifang Wang, Huifang Wang

“…Wheat (Triticum aestivum L.) is the most important cereal crop in arid and semiarid land areas, which are often adversely affected by soil salinity. …”
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African New Towns by Rachel Keeton

“…This research contributes to the existing body of literature on contemporary African New Towns (Watson 2014; Murray 2017; Van Noorloos and Kloosterboer 2018; Keeton and Provoost 2019). Notably, most authors working on this topic primarily employ internet sources or a single case study to build their arguments, which can be problematic in the African context where remotely-sourced data is often unreliable and New Towns as a group exhibit vast divergences that may limit the transferability of results from individual case studies. …”
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Temporal transcriptomic changes in the THY-Tau22 mouse model of tauopathy display cell type- and sex-specific differences by Muhammad Ali, Pierre Garcia, Laetitia P. Lunkes, Alessia Sciortino, Melanie H. Thomas, Tony Heurtaux, Kamil Grzyb, Rashi Halder, Alexander Skupin, Luc Buée, David Blum, Manuel Buttini, Enrico Glaab

“…Using differential statistical analysis for individual genes, pathways, and gene regulatory networks, we identified sex-specific, sex-dimorphic, and sex-neutral changes, and looked at how they evolved over age. To validate the most robust findings across distinct mouse models and species, the results were compared with cortical scRNA-seq data from the transgenic hAPP-based Tg2576 mouse model and human AD. …”
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One-year recurrence rate of new-onset atrial fibrillation after acute myocardial infarction by Alicia Prieto-Lobato, Víctor Hidalgo Olivares, Manuel Gerónimo Pardo, Marta Cubells Pastor, Francisco Manuel Salmerón Martínez, Miguel José Corbí-Pascual

“…Introduction and objectives: Atrial fibrillation (AF) is the most common cardiac arrhythmia worldwide, with a prevalence of up to 21% in the early phase of acute myocardial infarction (AMI). …”
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Application of Real-Time PCR Syndromic Panel on Lower Respiratory Tract Samples: Potential Use for Antimicrobial De-Escalation by Christian Leli, Paolo Bottino, Lidia Ferrara, Luigi Di Matteo, Franca Gotta, Daria Vay, Elisa Cornaglia, Mattia Zenato, Chiara Di Bella, Elisabetta Scomparin, Cesare Bolla, Valeria Bonato, Laura Savi, Annalisa Roveta, Antonio Maconi, Andrea Rocchetti

“…Molecular methods allow for a rapid identification of the main causative agents of pneumonia along with the most frequent resistance genes. Prolonged broad-spectrum antibiotic therapy without microbiological evidence of infection drives antimicrobial resistance. …”
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Perspectives of migrant men who have sex with men and professionals on personal, social and structural barriers and facilitators to sexual healthcare access and outreach strategies... by Chrissy PB Moonen, Christian JPA Hoebe, Casper DJ den Heijer, Jill Buursma, Marita ILS Werner, Ymke J Evers, Nicole HTM Dukers-Muijrers

“…., bars and schools). Notably, most participants accessed services through personal referrals, underlining the importance of including social networks in outreach strategies. …”
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Cognitive Disorders Awareness and Associated Risk Factors in Xizang Autonomous Region by HAO Yu, WANG Junshan, ZHUO Ma, SUOLANG Quzhen, JI Shiyong, HU Yaxiong, DING Zhijie, CIDAN Zhuoga, YUAN Jing, ZHAO Yuhua

“…The average age of respondents was 42.0±11.9 years; 108 (34.5%) were male, and 205 (65.5%) were female. Most respondents were from Lhasa (78.6%, 246/313); 179 (57.2%) were healthcare workers, and 134 (42.8%) were non-healthcare workers. …”
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Transcriptome analysis of insecticide resistance mechanisms in field populations of the bean flower thrips, Megalurothrips usitatus (Bagnall) by Hongyi Cao, Jiangjiang Yuan, Yanran Wan, Yingxi Tang, Xiaobin Zheng, Jing Wang, Kanghua Qian, Jiuming Feng, Sirui Chen, Youjun Zhang, Qingjun Wu

“…The NJ and YZ populations showed resistance to two and one insecticide, respectively, while the HP population was most susceptible. Elevated cytochrome P450s (CYP450), UDP-glycosyltransferases, and acetylcholinesterases activities were observed in the YZ population. …”
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Characterization of group B Streptococcus colonization in full-term and Late-Preterm neonates in Taiwan by Jen-Fu Hsu, Chyi-Liang Chen, Chien-Chung Lee, Reyin Lien, Shih-Ming Chu, Ren-Huei Fu, Ming-Chou Chiang, Chang-Yo Yang, Mei-Yin Lai, I-Hsyuan Wu, Yu-Shan Yen, Cheng-Hsun Chiu

“…In this group of 11 neonates, 4 had GBS serotypes II and III for 4–6 months, 1 had serotype V for 2 months, 6 had serotypes Ia, II, V, and VI for less than 1 month, and 1 had 2 different serotypes (serotypes V and II) at different times. The most prevalent serotype was II (33.3%), followed by Ia (25.0%), III (16.7%), V (16.7%), and VI (8.3%). …”
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SEED (Stoke Disease Early Detection Application) - Rancang Bangun Aplikasi Mobile Berbasis Android untuk Mendiagnosis Gejala Dini Penyakit Stroke Menggunakan K-Nearest Neighbor (K-... by Dedin Anike Putra, Muhammad Dimas Setiawan Sanapiah, Azifatul Istna Hanifah, Tri Afirianto

“…Stroke become the second most common cause of deadly disease in the world In modern era, young people can get this disease. …”
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Targeted Urinary Profiling as a Biomarker of Dietary Flavonoid Intake from Fruits and Vegetables and its Relationship to the Timing of Dietary Assessment by Emily B Hill, Anna Pashkova, Elizabeth M Grainger, Kristen M Roberts, Chureeporn Chitchumroonchokchai, Ashlea C Braun, Robin A Ralston, Ken M Riedl, Colleen K Spees, Steven K Clinton

“…Results: Compared to estimated intakes from a 1 d or 3 d diet record, total urinary flavonoids were most strongly associated with total FV (excluding potatoes) (rs = 0.53, P = 0.028) and total FV flavonoid (rs = 0.60, P = 0.011) intakes estimated by a 2 d diet record (including the day before and the day of the 24-h urine collection). …”
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Genomic insights into the population structure, antimicrobial resistance, and virulence of Brachyspira hyodysenteriae from diverse geographical regions by Maria Hakimi, Fangshu Ye, Anugrah Saxena, Xiao Hu, Huigang Shen, Paarthiphan Elankumaran, Chloe C. Stinman, Nubia Macedo, Orhan Sahin, Eric R. Burrough, Ganwu Li

“…Virulence factor analysis identified genes linked to hemolysin production, iron uptake, and survival in host environments in most isolates, with a subset of genes demonstrating lineage-specific associations that are further linked to pathogenic potential. …”
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Options to apply national developments in the assessment of sentinel lymph node involvement in breast cancer by M. V. Shomova, E. P. Kulikov, A. N. Demko, I. I. Vinogradov, A. D. Gerasimova, A. N. Budanov

“…The fluorescent method is among the most promising. This technique has been used for many years. …”
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Genome diversity of SARS-CoV-2 lineages associated with vaccination breakthrough infections in Addis Ababa, Ethiopia by Abebe M. Aga, Demise Mulugeta, Atsbeha Gebreegziabxier, Girum Taye Zeleke, Aderajew Mekonnen Girmay, Gutema Bulti Tura, Abaysew Ayele, Ahmed Mohammed, Tigist Belete, Tefera Taddele, Rajiha Abubeker, Fanos Tadesse Woldemariyam, Tesfaye Gelanew, Yeweynshet Tesera, Bedasa Gidisa, Jaleta Bulti Tura, Gemechu Tadesse Leta, Abraham Ali, Senait Alemayehu Beshah, Bedasa Wagari Likasa, Jemal Mohammed, Dereje Nigussie

“…The analysis showed that all cases were of the Omicron variant, with the XBB.1.5 lineage being the most prevalent (38.4%), followed by FL.2 (9.3%) and XBB.1.9.1.2 (7.8%). …”
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