Sex-Related Differences in Glioblastoma: A Single-Center Retrospective Cohort Study by Chiara Prosperetti, Meltem Yenigün, Alberto Pagnamenta, Payam Tabaee Damavandi, Giulio Disanto, Francesco Marchi, Vittoria Espeli, Barbara Muoio, Paolo Spina, Gianfranco Pesce, Pamela Agazzi

“…<b>Background</b>: Sex differences play a significant role in the epidemiology, biology, and outcomes of many cancers, including glioblastoma (GB), the most common and aggressive primary brain tumor. GB is more frequent in males, while females tend to have longer survival, though the underlying reasons for these differences remain poorly understood. …”
Get full text

Volatile organic compounds from typical industries in North China Plain: emissions, air pollution contribution, health risks, and policy implications by Jiqi Zhu, Shoujun Xia, Hejingying Niu, Jian Xu, Yueqian Wang, Xuena Yu, Ling Huang, Kun Zhang, Yangjun Wang, Limin Zeng, Qing Li, Li Li

“…Results indicate that: (1) Current emission factors of industrial VOCs diverged substantially, with petrochemical (15.93 kg/t) and pharmaceutical (135 kg/t) industries being the most obvious emission sectors. (2) Chemical composition of VOCs varied across different industries, with surface coating emitting 69 % halogenated hydrocarbons, petrochemicals releasing 58 % aromatics, and pharmaceuticals discharging 53 % oxygenated VOCs (OVOCs). (3) Ozone formation potential peaked in surface coating (351.9 mg/m3, aromatics-driven) and olefin-rich organic chemical processes, while secondary organic aerosol potential was dominated by petrochemical aromatics (5,750 μg/m3). (4) Health risks are high in resin and plastic, pharmaceutical, and petroleum industries, with acrolein (HQ = 0.96) and acetaldehyde (cancer risk = 3.9 × 10-7) as priority hazards. (5) Based on detected greenhouse-effect VOCs, Freon-12/11 emissions dominated climate impacts (83 %, 467.1 tCO2-eq) in the petrochemical industry. (6) Entropy-weighted analysis prioritized petroleum for Tier-1 controls. …”
Get full text

Validação de questionário para diagnóstico de cefaléia em ambulatório de hospital universitário Validation of a headache questionnaire in an outpatient clinic of an universitary ho... by Isabela J. M. Benseñor, Paulo A. Lotufo, Alexandre C. Pereira, Anna Cristina A. Tannuri, Flávia K. K. Issa, Daniela Akashi, Daniele Q. Fucciolo, Everton Y. S. Kakuda, Hideki Kanashiro, Maurício L. Lobato, Sílvia M. O. Titan, Tatiana F. G. Galvão, Milton de Arruda Martins

“…We compared the results of the questionnaire with the results of the medical interview (gold standard). Most of the headaches we studied were primary headaches (89.6%). …”
Get full text

Chronic Kidney Disease-Associated Pruritus in Patients Undergoing Haemodialysis—A Cross-Sectional Study by Teng Wang, Jing-Xin Goh, Wubshet Tesfaye, Kamal Sud, Connie Van, Linda Le Do, Surjit Tarafdar, Ronald L. Castelino

“…In total, 27 patients (40%) reported having CKD-aP. Most participants experienced moderate CKD-aP severity (<i>n</i> = 12), followed by severe or very severe (<i>n</i> = 9) and mild (<i>n</i> = 6) symptoms. …”
Get full text

SENTINEL LYMPH NODE BIOPSY IN PREVENTING REGIONAL RELAPSES IN PATIENTS WITH LOCALLY ADVANCED CUTANEOUS MELANOMA by D. V. Kudryavtsev, G. T. Kudryavtseva, Yu. V. Gumenetskaya, G. A. Davydov, N. A. Oleynik, N. Yu. Dvinskikh, А. L. Starodubtsev

“…The investigation of SLN is the most  effective, safe,  and reproducible  technique  for the early detection of subclinical  regional  metastases and for the  prevention  of  regional relapses  in patients  with locally advanced  CM. …”
Get full text

Joint health status in people with moderate hemophilia A: a cross-sectional multicenter study by Ilenia Lorenza Calcaterra, Federico Picasso, Federica Valeri, Erminia Baldacci, Mariasanta Napolitano, Cornelia Guerrino, Ezio Zanon, Cristina Santoro, Sergio Siragusa, Carlo Martinoli, Matteo Nicola Dario Di Minno

“…Analysis at the joint level showed that the most commonly affected joint was the ankle, both for osteochondral damage and the presence of HS. …”
Get full text

Identification and validation of NEIL2 as a prognostic biomarker and potential therapeutic target in cervical cancer by Yan Li, Jiayuan Du, Lingjia Wei, Tianmeng Tan, Liyi Bao, Jinqiu Su, He Wang

“…An alignment diagram based on independent prognostic factors was constructed. In addition, the most relevant modules with NEIL2 expression were screened separately by weighted gene co-expression network analysis in TCGA-CESC and GSE7410, followed by intersection to obtain NEIL2-related hub genes. …”
Get full text

Analysis of microbial composition in different dry skin areas of Beijing women by Jingtao Wang, Benyue Li, Yuanman Zhang, Wei Ma, Ting Jia, Jie Yang, Yexiang Zhang, Fengwei Qi, Yan Jia, Liya Song

“…IntroductionThe composition of the skin microbiota is shaped by the interaction of multiple factors, with area-specific changes and physiological characteristics in the skin having the most profound impact. The back of the hand and lower leg are two dry areas of human skin. …”
Get full text

OCTA changes of retinal microvessels and thickness in moyamoya disease by Xian-Zhe Qian, Cheng Chen, Hong-Liang Li, Lei Zhong, Hong Wei, Qian-Min Ge, Jin-Yu Hu, Qi Hong, Xiao-Yu Wang, Yan-Mei Zeng, Xu Chen, Yi-Xin Wang, Chong-Gang Pei, Yi Shao

“…The above findings indicate significant reduction in the SMC-VD and the MRT in patients with MMD even in the absence of ocular clinical manifestation. Most importantly, SMC-VD and MRT have a strong ability to distinguish between MMD patients and HC, suggesting that OCTA, a relatively inexpensive and non-invasive method, is useful in assessing cerebrovascular changes in MMD patients.…”
Get full text

Epicoccin A Ameliorates PD-like Symptoms in Zebrafish: Enhancement of PINK1/Parkin-Dependent Mitophagy and Inhibition of Excessive Oxidative Stress by Haicheng Ye, Dan Li, Lei Zhang, Yufei Wang, Cong Wang, Meng Jin, Houwen Lin, Peihai Li, Chen Sun, Ning Li

“…Parkinson’s disease (PD) is the second most prevalent neurodegenerative disorder, yet effective agents for its prevention and therapy remain highly limited. …”
Get full text

The Epidemiological Characteristics of Coronavirus Disease (COVID-19) in Halabja Province/Kurdistan –Iraq by Osama Hamid Shareef, Othman Abdulrahman Mohammed, Dashty Aziz Ghafor, Ari Shareef Ali, Hardi Rafat Baqi, Ali Aziz Ali, Aryan Mahmood Faraj, Syamand Ahmed Qadir, Ali Muhi Aldeen Omar Aljabary

“…The result of this study for both sexes, revealed that, the most confirmed cases among (30-39) years group and (40-49) years group were (1521) and (1223) confirmed positive cases. …”
Get full text

Development and application of metallic dampers in bridge engineering: A review by Wenxi Wang, Sheng Chen, Bei Chen, Guokun Liu, Xugang Hua, Zhengqing Chen

“…Metallic dampers employed the energy dissipation from the hysteretic behavior of metal materials are among the most effective methods to mitigate bridge vibrations. …”
Get full text

Problems of analysis of the relationship between the learning context and TIMSS testing results by L. M. Nurieva, S. G. Kiselev

“…The TIMSS datasets were analysed using the IEA International Database (IDB) parser plug-in for SPSS (version 4.0).Results. For most indicators of the social and student context of learning, the authors found the absence or low value of statistical relationships with TIMSS scores. …”
Get full text

Enrollment and Retention Outcomes from the Veterans Health Administration for a Remote Digital Health Study: Multisite Observational Study by Jaclyn A Pagliaro, Lauren K Wash, Ka Ly, Jenny Mathew, Alison Leibowitz, Ryan Cabrera, Jolie B Wormwood, Varsha G Vimalananda

“…Among those enrolled, completers and noncompleters were similar except for a slightly higher proportion of patients with hypertension among completers. The most common reason for noncompletion of the study was that participants were unable to be contacted for study tasks. …”
Get full text

Clinical medication guidance for hypertension personalization through pharmacogenomic research and analysis by Qian Ren, Shoulei Wang, Yansong Ren, Chang Liu

“…Results: We obtained a significant difference in ADRB1(1165 G>C) between males and females, and the allele mutation frequency of ACE I/D was found to be higher in the Beijing population. Conclusion: Most hypertensive patients in the Beijing region carry a high frequency of CYP2D6 * 10, ADRB1(1165 G>C), and ACE I/D genes, implying that they might be more sensitive to β-blockers, potentially benefitting more from ACEI drugs. …”
Get full text

Evaluation of the Bactericidal Activity of Gramicidin S Against <i>Streptococcus pneumoniae</i> and <i>Staphylococcus aureus</i> Clinical Isolates with Single and Multiple Exposure by A. V. GUROV, K. E. BOROVKOVA, K. L. KRYSHEN, L. R. NIKIFOROVA, J. V. SALMOVA

“…Sore throat of infectious and inflammatory origin is one of the most common reasons for the prescription of antimicrobial drugs. …”
Get full text

Mutation profile of the tall cell variant of papillary thyroid carcinoma: analysis of 5 cases using wide-panel next-generation sequencing by I. L. Plaksa, M. R. Savchuk, N. V. Shved, N. A. Savelov, D. N. Khmelkova, А. A. Isaev, R. V. Deev

“…One individual with the largest tumor and the most aggressive disease was found to have amplifications of the BTG2, MAP3K1, SMAD2, and TBX3 genes.Conclusion. …”
Get full text

Automated interaction may reduce emotional reactivity in VR: a randomized study with healthy participants by Julia Elisabeth Diemer, Julia Elisabeth Diemer, Magdalena Sich, Bastian Lange, Mathias Müller, Marius Koller, Philip Schäfer, Gerrit Meixner, Alexander Brunnauer, Alexander Brunnauer, Peter Zwanzger, Peter Zwanzger

“…IntroductionVirtual reality (VR) has been investigated as a psychotherapy tool for 3 decades, with the most recent developments introducing automated self-help programs without direct therapeutic assistance. …”
Get full text

PO13 | Monitoring of anti-factor XA activity levels in patients treated with direct oral anticoagulants and concomitant tyrosine kinase inhibitors agents: a monocentric experience

“…Conclusions: Combination of DOACs and TKIs appears generally safe, with most patients achieving appropriate anti-Xa levels. …”
Get full text

Sarcopenia Is Associated With Increased Risk of Abnormal Sleep Duration in the Older People: A 10‐Year Cohort Study From China by Yimi Wang, Weixin Chen, Chun Wang, Lingzhi Li, Bingqing Bi, Shugang Li, Hao Wu

“…ABSTRACT Background With the acceleration of the aging process, health issues of older people have gradually become one of the most important research topics. The older people experience significant reductions in muscle mass and physical performance. …”
Get full text