Combining treatments for migraine prophylaxis: the state-of-the-art by Lanfranco Pellesi, David Garcia-Azorin, Eloisa Rubio-Beltrán, Wook-Seok Ha, Roberta Messina, Raffaele Ornello, Igor Petrusic, Bianca Raffaelli, Alejandro Labastida-Ramirez, Ruth Ruscheweyh, Claudio Tana, Doga Vuralli, Marta Waliszewska-Prosół, Wei Wang, William Wells-Gatnik

“…Despite the potential of these combinations, there is a lack of evidence to support their widespread inclusion in clinical guidelines. The high cost of certain combinations, such as onabotulinumtoxin A with a CGRP mAb or dual anti-CGRP mAbs, presents feasibility challenges. …”
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Why engagement matters in policy implementation: an examination of the engagement of policy actors in the implementation of a mental health and addictions strategy by Heather L. Bullock, John N. Lavis, Gillian Mulvale, Michael G. Wilson, Celine Mulhern

“…Conclusion Our findings point to five practical insights for policymakers and implementers: being attentive to the power distribution among actors, the importance of building and maintaining trust amongst actors, the opportunity-cost of taking a NPG approach, the timing/sequencing of the process, and the need for careful consider of the type of actors involved and the expertise they bring.…”
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The Effect of Zinc Supplementation On Resolution Of Symptoms In Pediatric Pneumonia by Madiha Fayyaz, Zartasha Sial, Anam Raheel, Muqaddas Jamshed, Mahreen Ashraf, Sehar Zahid

“…Hence, adding zinc can reduce the hospital stay which will surely reduce the related cost while enhancing parents’ and physicians’ satisfaction. …”
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Unlocking the potential of established products: toward new incentives rewarding innovation in Europe by Gabrielle Nayroles, Sandrine Frybourg, Sylvie Gabriel, Åsa Kornfeld, Fernando Antoñanzas-Villar, Jaime Espín, Claudio Jommi, Nello Martini, Gérard de Pouvourville, Keith Tolley, Jürgen Wasem, Mondher Toumi

“…This represents a potentially missed opportunity as developing new indications for EPs offers an alternative to off-label use or lengthy and expensive R&D for new therapies, opens new opportunities for potentially cost-effective treatment alternatives, as well as greater equity in patients’ access to treatment options. …”
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Using microdata as a basis for long term projections of hospital care spending: the added value of more detailed information by Peter Paul F. Klein, Sigur Gouwens, Katalin Katona, Niek Stadhouders, Talitha L. Feenstra

“…Incorporating these trends into cost projections for various disease groups results in more conservative estimates of future hospital spending compared to merely using demographic projections of per capita costs and adjusting them for observed historical growth. …”
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Effects of Cholesterol Supplementation in High Soybean Meal Diet on Growth, Lipid Metabolism, and Intestinal Health of Juvenile Rice Field Eel Monopterus albus by Kai Xie, Xiang Liu, Yong Shi, Minglang Cai, Jihong Dai, Junzhi Zhang, Yi Hu

“…The rising cost of fish meal (FM) in aquaculture feed has prompted the search for alternative protein sources like soybean meal (SBM). …”
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Genes and genetics belong to maize haploid induction by Kanogporn Khammona, Kanogporn Khammona, Abil Dermail, Yu-Ru Chen, Thomas Lübberstedt, Samart Wanchana, Theerayut Toojinda, Siwaret Arikit, Siwaret Arikit, Vinitchan Ruanjaichon

“…The rapid development of homozygous inbred lines via double haploid (DH) technology has revolutionized maize breeding, reducing the time and cost required for cultivar improvement. This review synthesizes advances in haploid induction systems, focusing on the genetic mechanisms underlying both paternal and maternal inducers. …”
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Analysis of the height difference of the zero isotherm according to two temperature profilers by E. A. Bolelov, O. V. Vasiliev, K. I. Galaeva, S. A. Ziabkin

“…This, in conjunction with the sufficiently low cost of the network of aerological stations on the territory of the Russian Federation does not allow the operational use of radiosonding data to determine the height of the zero isotherm at a particular airport. …”
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Synthesis of Zeolitic Imidazolate Framework-8 from Waste Electrodes via Ball Milling for Efficient Uranium Removal by Minhua Su, Jinyao Zhu, Ruoning Wu, Jiaqi Pan, Jingran Yang, Jiaxue Zhao, Diyun Chen, Changzhong Liao, Kaimin Shih, Shengshou Ma

“…Developing a cost-effective approach for the remediation of wastewater containing uranyl [U(VI)] ions is essentially important to ecosystems and human health. …”
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Development of a protective lyophilisation medium and conditions to stabilise the erythrocyte diagnostic preparation of tularaemia immunoglobulin by S. A. Kurcheva, A. G. Koshkidko, I. V. Zharnikova, D. V. Rusanova, A. A. Semircheva, O. L. Startseva, E. V. Zhdanova, M. M. Kurnoskina, I. S. Tyumentseva

“…The authors carried out practical evaluation of lyophilisation procedures, and the 12–14-hour procedure proved to be the most cost-effective. Conclusions: The results of long-term, or real time, and accelerated stability testing of the lyophilised diagnostic preparation demonstrated the possibility of two-year storage at a labelled temperature of 2–8 °C, as well as at elevated and low temperatures of 30±2 °С and –18 °С, respectively. …”
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Optimizing Cancer Detection: Swarm Algorithms Combined with Deep Learning in Colon and Lung Cancer using Biomedical Images by HariKrishna Pathipati, Lova Naga Babu Ramisetti, Desidi Narsimha Reddy, Swetha Pesaru, Mashetty Balakrishna, Thota Anitha

“…Machine learning (ML) and deep learning (DL) approaches are employed to haste up cancer recognition, letting researchers to analysis a great amount of patients in a short period of time and at a low cost. This research presents an Optimizing Cancer Detection using whale optimizer with Deep Learning in Colon and Lung Cancer (OCDWO-DLCLC) model on Biomedical Images. …”
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Effect on the Electrochemical Properties of PEO Films Produced on Commercially Pure Titanium Using Multicomponent Oxide Coatings by Lauri Ruberti, Heloisa Andréa Acciari, Diego Rafael Nespeque Correa, Yasmin Bastos Pissolitto, Elidiane Cipriano Rangel, Francisco Trivinho-Strixino, Nilson Cristino da Cruz

“…Titanium has specific uses due to its cost, which is counterbalanced by its extraordinary chemical and physical properties. …”
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Dual Therapy Treatment Strategies for the Management of Patients Infected with HIV: A Systematic Review of Current Evidence in ARV-Naive or ARV-Experienced, Virologically Suppresse... by Jean-Guy Baril, Jonathan B Angel, M John Gill, Joseph Gathe, Pedro Cahn, Jean van Wyk, Sharon Walmsley

“…<h4>Conclusions</h4>The potential benefits of dual therapy regimens include reduced toxicity, improved tolerability and adherence, and reduced cost. Although the data reviewed here provide valuable insights into the effectiveness and tolerability of dual therapy regimens, it remains unclear whether these potential benefits can be maintained long-term. …”
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Effect of gum chewing and cold therapy on postoperative cesarean women’s self-assessed pain levels and narcotics use: a comparative study by Reda Mhmoud Mohamed Hables, Nor El-Hoda Mohamed El-Sayed ElShabory, Esraa Mostafa Abd El-Aty Ibrahim

“…Conclusion Cold pack gel and gum chewing offer simple and cost-effective alternatives for postoperative pain management; however, cold pack gel has been shown to be substantially more effective in improving pain scores at four, eight, twelve, and twenty-four hours after surgery. …”
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3D bioprinted colorectal co-culture model to explore nanoparticles targeting and stimuli responsive treatments against cancer by Giorgia Savino, Giada Rosso, Maria D’Aloia, Ignazio Roppolo, Valentina Cauda

“…Current animal models often fail to accurately predict human outcomes, highlighting the need for better testing platforms.Three-dimensional (3D) colorectal cancer models provide an ethical, cost-effective alternative to animal studies, mimicking human tumor microenvironments with high fidelity. …”
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Comparison of two quantitative real time PCR assays for Rickettsia detection in patients from Tunisia. by Abir Znazen, Hanen Sellami, Emna Elleuch, Zouhour Hattab, Laroussi Ben Sassi, Fatma Khrouf, Hassen Dammak, Amel Letaief, Mounir Ben Jemaa, Adnene Hammami

“…However, its implementation in routine needs cost/effectiveness evaluation.…”
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Cow dung waste as an eco-friendly adsorbent for Alizarin Red S dye removal by Ali El-Rayyes, Abidemi Mercy Babatimehin, Moamen S. Refat, Amnah Mohammed Alsuhaibani, Akeem Adesina Bamigbade, Nathanael Yinka Ilesanmi, Edwin Andrew Ofudje

“…These results suggest that cow dung waste, especially when treated, is a promising, cost-effective, and eco-friendly adsorbent for the removal of organic contaminants like ARS from wastewater.…”
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Growth Rate Prediction, Performance, and Biochemical Enhancement of Black Soldier Fly (<i>Hermetia illucens</i>) Fed with Marine By-Products and Co-Products: A Potential Value-Adde... by Daniela P. Rodrigues, Ricardo Calado, Marisa Pinho, M. do Rosário Domingues, José Antonio Vázquez, Olga M. C. C. Ameixa

“…Aquafeed production is a fast-growing industry, seeking novel, cost-efficient raw materials to diversify traditional ingredients like fish meal and oil. …”
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"Em todos os lares, o conforto moral da ciência e da arte": a Revista Nacional de Educação e a divulgação científica no Brasil (1932-34) "In all homes, the moral comfort of science... by Regina Horta Duarte

“…Every issue was published at a low cost, with a significant number of copies. The journal was touted as the initiative of a renewed Republic, part of a broader strategy of inaugurating new relations between government and a population to be educated. …”
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Recent Advances in Resistive Gas Sensors: Fundamentals, Material and Device Design, and Intelligent Applications by Peiqingfeng Wang, Shusheng Xu, Xuerong Shi, Jiaqing Zhu, Haichao Xiong, Huimin Wen

“…Resistive gas sensors have attracted significant attention due to their simple architecture, low cost, and ease of integration, with widespread applications in environmental monitoring, industrial safety, and healthcare diagnostics. …”
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