Strengthening phage resistance of Streptococcus thermophilus by leveraging complementary defense systems by Audrey Leprince, Justine Lefrançois, Anne M. Millen, Damian Magill, Philippe Horvath, Dennis A. Romero, Geneviève M. Rousseau, Sylvain Moineau

“…We also assess the fitness cost associated with the chromosomal integration of these systems in their native context and find no impact under laboratory or industrial conditions. …”
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Enhancing Sialidase Production from the <i>Oerskovia paurometabola</i> O129 Strain by the Optimization of Fermentation Parameters and the Addition of Stimulative Compounds by Yana Gocheva, Ekaterina Krumova, Irina Lazarkevich, Rumyana Eneva, Stephan Engibarov

“…Maximum enzyme production (98.3 U/mL), representing about a three-fold increase compared to non-optimized conditions, was obtained by culturing the strain under optimal conditions and by the synergistic action of glucomacropeptide and Tween 80. A new, simple, and cost-effective laboratory model for optimizing sialidase production by the saprophytic strain <i>O. paurometabola</i> O129 in submerged fermentation was proposed. …”
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Predicting the Evolution of Extreme Water Levels With Long Short‐Term Memory Station‐Based Approximated Models and Transfer Learning Techniques by Samuel Daramola, David F. Muñoz, Paul Muñoz, Siddharth Saksena, Jennifer Irish

“…To date, physically based models have enabled accurate prediction of EWLs despite their inherent high computational cost. However, the applicability of these models is limited to data‐rich sites with diverse characteristics. …”
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Deep Learning-Based Keras Network Formulation for Predicting the Shear Capacity of Squat RC Walls and Sensitivity Analysis by Badie H. Sulaiman, Amer M. Ibrahim, Hadeel J. Imran

“…It is distinguished by its optimal cost and excellent performance. Nonetheless, precise assessment of the shear strength of squat shear walls is crucial for design specifications, and its computation can be exceedingly variable and intricate due to several efficient, expensive, and time-consuming constraining elements. …”
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The role of in-house safety professionals in influencing organizational safety performance across global industries by Chi-Yang Li, Zhuoran Zhang, Haoyu Yang, Michael Larranaga, Miaozong Wu, James McIntosh, Qingsheng Wang

“…Safety professionals play a crucial role in assessing and managing organizational risks, with their contributions widely recognized for life and cost savings. Organizations employing in-house safety professionals have reported a 60% lower accident frequency rate, a key lagging indicator, compared to those relying solely on external safety consultants. …”
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Enhancing the removal of total dissolved solids from petroleum wastewater through electrocoagulation by Muhammad Jasim, Forat AlJaberi, Saja Alardhi, Ali Salman, Mustafa Hathal, Igor Cretescu, Armando Vargas

“…The energy consumption was 3.65 kWh/m3, and the total operating cost was only 0.74 $ per m3. This study confirms the efficacy of the novel continuous reactor in managing petroleum wastewater under practical conditions with low consumption values of electrodes and electrical energy.…”
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Shunt active power filter using model predictive control with stability guarantee by Jhon Pérez-Ramírez, Diego Montoya-Acevedo, Walter Gil-González, Oscar Danilo Montoya, Carlos Restrepo

“…This paper presents a model predictive control (MPC) strategy to solve an optimization problem based on system state and control variables, subject to constraints imposed by the control objective. The cost function exhibits convex characteristics, ensuring a unique control law. …”
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McLean OCD Institute for Children and Adolescents: Overview, Rationale, and Description of Symptomatology and Functional Impairment by Alyssa L. Faro, Rebecca A. Wolenski, Chun W. Lee, Perihan Esra Guvenek-Cokol, Daniel P. Dickstein, Maria G Fraire

“…Despite accumulating evidence supporting the treatment efficacy and cost-effectiveness of insurance-based intensive OCD treatment in residential settings, few data exist that characterize the population of adolescent patients utilizing this level of care. …”
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Low-Latency Neural Network for Efficient Hyperspectral Image Classification by Chunchao Li, Jun Li, Mingrui Peng, Behnood Rasti, Puhong Duan, Xuebin Tang, Xiaoguang Ma

“…However, theoretical floating-point operations alone are not enough to evaluate real-time quality, especially in scenarios where inference latency is highly influenced by memory access cost and hardware characteristics. To address these challenges, we create a low-latency-oriented network architecture for HSIC, which is adaptable to any dataset without requiring architectural adjustments. …”
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Performance evaluation, prediction analysis and optimization of experimental ORC using artificial neural networks (ANN) by Diki Ismail Permana, Federico Fagioli, Maurizio De Lucia, Dani Rusirawan, Istvan Farkas

“…Additionally, a multi-objective optimization approach is used to simultaneously maximize net output work and thermal efficiency, setting a benchmark for efficient, low-cost, and sustainable ORC system designs. The benefits of this research include advancing predictive modeling for ORC systems, improving resource efficiency, and providing insights into optimized ORC operations for real-world applications.…”
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Limited and inconclusive effects of computer-based neurocognitive training on PTSD, comorbid depression and executive functioning: a systematic review and meta-analysis by Patric Muschner, Lena Goldschmidt, Luisa Sophie Gröning, Gerd-Dieter Willmund, Martina Piefke

“…C-bnt is a potentially promising, cost-effective treatment that warrants exploration as an adjunctive therapy for PTSD.…”
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Accurate and affordable multi-cancer early detection and localization via plasma cfDNA multi-omic profiling by Pin Cui, Weihuang He, Mingji Feng, Hanming Lai

“…Therefore, methylation profile, a widely used epigenetic biomarker, can be obtained from a simple WGS assay for MCED in a cost-efficient manner. Interpretation: To further explore the potential of our method for MCED, we are recruiting more than 2000 plasma samples from a retrospective cohort covering 12 common cancers in China, including cancers in lung, liver, colon, gastric, pancreas, esophagus, breast, cervix, kidney, nasopharyngeal, bile duct, and gallbladder. …”
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Lean Six Sigma as a Management Tool Helps Standardize Antimicrobial Use in Hospital Settings by Wang Q, Han X, Zhang X, Guo L

“…Additionally, the utilization rate of antibacterial drugs has dropped from 43.61% to 40.16% (P &lt; 0.0001), and the average cost of antibacterial drugs per inpatient significantly dropped from 1909.59 RMB (known as Renminbi, which is the legal currency of China) to 1675.20 RMB (P &lt; 0.0001), resulting in substantial annual savings.Conclusion: The application of the LSS-DMAIC model effectively improved the rational use of antibacterial drugs in the hospital, demonstrating its potential as a valuable management tool in healthcare settings. …”
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A Sustainable Energy Management Evaluation and Decision-Making Framework of Hybrid Solar Geyser-Stove System in Domestic buildings by Muhammad Nauman Fazal, Abdullah Altamimi, Syed Ali Abbas Kazmi, Zafar A. Khan, Faisal Asfand

“…This study assesses hybrid solar geyser and stove systems across techno-economic and environmental dimensions by utilizing the Multi-Criteria Decision-Making (MCDM) framework, focusing on energy efficiency, cost-effectiveness, environmental sustainability, and user comfort. …”
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Stabilising the Integrity of Snake Venom mRNA Stored under Tropical Field Conditions Expands Research Horizons. by Gareth Whiteley, Rhiannon A E Logan, Kam-Yin D Leung, Fiona J Newberry, Paul D Rowley, John P Dunbar, Simon C Wagstaff, Nicholas R Casewell, Robert A Harrison

“…We demonstrated that venom can be stored in TRIzol for 48 hours at 4-19°C, and 8 hours at 37°C, at minimal cost to RNA quality, and found that venom RNA encoded multiple toxin isoforms that seemed homologous (98-99% identity) to those found in the venom gland.…”
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Shared energy storage planning based on the adjustable potential of data center based on visual IOT platform by Lei Su, Wanli Feng, Haoyu Ma, Mingjiang Wei, RuoShi Gu, Ziya Chen, Junda Qin

“…Abstract To address the challenges of low utilization and poor economic efficiency associated with decentralized energy storage configurations in data centers, this study proposes a shared energy storage planning method for data center groups based on the adjustable potential of data center based on visual IOT platform, which leverages differences and complementarities in energy storage requirements under different scenarios to minimize investment costs while maximizing operational benefit. First, we establish a shared energy storage operation framework governed by a capacity allocation, cost-sharing mechanisms, and a Nash bargaining-based profit distribution model under different scenarios to ensure equitable benefits for alliance members. …”
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Perceptions of the Intensity of Heart Failure Medications among Hospitalized Older Adults: A Pilot Qualitative Study by Nuzha A. Amjad, Saeed Shoar, Catherine Bryant, Meghan Hunt, Min Ji Kwak

“…The most common themes were experiencing adverse drug effects (80%) and psychological distress (80%), followed by problems in logistics (70%), the burden from the number of medications (70%), impact from patient-doctor relations (70%), and burden from the cost (40%). Conclusions The results from this pilot study provide preliminary insight into the perceived challenges of HF medication utilization and the distinctive ways the treatment burden is experienced by patients. …”
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Green Hydrogen Role in Sustainable Energy Transformations: A Review by Sameer Algburi, Hassan Munther, Omer Al-Dulaimi, Hassan Falah Fakhruldeen, I.B. Sapaev, Karrar Fadhil Khalaf Al Seedi, Doaa H. Khalaf, Feryal Ibrahim Jabbar, Qusay Hassan, Ali Khudhair, Grace Nakimera

“…However, global investments and policy initiatives are driving cost reductions, with projections indicating a decline in production costs to below $2/kg by 2030. …”
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Probiotics against pathogenic bacteria and cancer by V. A. Belyavskaya, N. V. Cherdyntseva, N. V. Litviakov, A. A. Ponomaryova, E. V. Udut

“…Current anticancer drugs often have significant drawbacks, including negative impact on patients’ quality of life, development of drug resistance, and high cost. Conclusion. The effectiveness of probiotic therapies appears to be influenced by several factors, such as the specific bacterial or fungal strain used, the dosage administered, and the duration of treatment. …”
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A sustainable approach to helminth eggs concentrations removal in sewage sludge from biological wastewater treatment: A Brazilian case study by Guilherme Sgobbi Zagui, Lisandro Simão, Danielma Silva Maia, Brisa Maria Fregonesi, Karina Aparecida Abreu Tonani, Marília Vasconcellos Agnesini, Cristina Filomena Pereira Rosa Paschoalato, Susana Inés Segura-Muñoz

“…In this study, we evaluated helminth eggs in raw and treated sewage sludge after thermal drying in an agricultural greenhouse, from two wastewater treatment plants (namely WWTP-A and WWTP-B), in intention of verifying a low-cost treatment technology to obtain treated sewage sludge for agricultural purposes. …”
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