Analysis of treatment patterns and persistence on branded and generic medications in major depressive disorder using retrospective claims data by Solem CT, Shelbaya A, Wan Y, Deshpande CG, Alvir J, Pappadopulos E

“…., Global Health Outcomes, New York, NY, 3Epidemiology Department of Mailman’s School of Public Health, Columbia University Mailman School of Public Health, New York, NY, USA Background: In major depressive disorder (MDD), treatment persistence is critical to optimize symptom remission, functional recovery, and health care costs. Desvenlafaxine tends to have fewer drug interactions and better tolerability than other MDD drugs; however, its use has not been assessed in the real world.Objective: The aim of the present study is to compare medication persistence and concomitant MDD drug use with branded desvenlafaxine (Pristiq®) compared with antidepressant drug groups classified as 1) branded selective serotonin reuptake inhibitors (SSRIs; ie, escitalopram [Lexapro™]) and selective serotonin–norepinephrine reuptake inhibitors (SNRIs; ie, venlafaxine [Effexor®], duloxetine [Cymbalta®]) and 2) generic SSRIs/SNRIs (ie, escitalopram, citalopram, venlafaxine, fluvoxamine, fluoxetine, sertraline, paroxetine, and duloxetine).Patients and methods: MDD patients (ICD-9-CM codes 296.2, 296.3), with ≥2 prescription fills for study drugs and 12-month preindex continuous enrollment from the MarketScan Commercial Claims and Encounters Database (2009–2013), were included. …”
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Modeling of project activities for UAV modernization to conduct swarm drone attack missions by Oleg Fedorovych, Leonid Malieiev, Oleksii Hubka, Andrei Popov

“…While innovative components enhance UAV capabilities, they also increase project duration, costs, and associated risks – factors that are particularly critical during a state of war. …”
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Kinerja Metode Rank Sum, Rank Reciprocal dan Rank Order Centroid Menggunakan Referensi Poin Moora (Studi Kasus: Bantuan Kuota Data Internet untuk Mahasiswa) by Ummul Hairah, Edy Budiman

“…The decision-making criteria for internet data quota assistance are based on the needs of online learning and the ability of the student's economic costs. The weight ranking method uses the Rank Sum (RS) weighting technique, the Reciprocal Rank (RR) and the Rank Order Centroid (RoC), with the decision analysis method uses the reference point Moora. …”
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Energy optimization and plant comfort management in smart greenhouses using the artificial bee colony algorithm by Muhammad Jawad, Fazli Wahid, Sikandar Ali, Yingliang Ma, Ahmed Alkhyyat, Jawad Khan, Youngmoon Lee

“…It is important to note that the research being done has the potential to minimize operating costs and maximize the amount of energy needed for plant growth, thereby creating a model for sustainable greenhouse agriculture.…”
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A qualitative pilot study exploring the acceptability of a peer provider delivered substance use brief intervention from the perspective of youth in Kenya by Florence Jaguga, Matthew C. Aalsma, Leslie A. Enane, Matthew Turissini, Edith Kamaru Kwobah, Edith Apondi, Julius Barasa, Gilliane Kosgei, Yvonne Olando, Mary A. Ott

“…They reported that the goal of the intervention was to help youth stop substance use, and to bring about behavior change. Opportunity costs: Some youth reported that they had to forgo other activities to attend the session, such as work, school, sports, gaming, visiting family, or house chores. …”
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A deep learning framework to map riverbed sand mining budgets in large tropical deltas by Sonu Kumar, Edward Park, Dung Duc Tran, Jingyu Wang, Huu Loc Ho, Lian Feng, Sameh A. Kantoush, Doan Van Binh, Dongfeng Li, Adam D. Switzer

“…Conventionally, bathymetry surveys and compilation of declared amounts have been used to quantify SM budgets, but they are often costly and laborious, or result in inaccurate quantification. …”
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Evaluación computarizada del terreno para una finca en Tenjo-Colombia Computerized land evaluation to a farm in Tenjo-Colombia by Madero Morales Edgar Enrique

“…The factors which affect the harvest yield have more influence over the profits than those factors which affect the costs of production. 3. Dairy cattle was the most profitable use but requiere large infrastructure and access to capital; barley is ideal because it is relatively mostly rustic, does not need a high capital investment and usualy have a low loss. …”
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The Earth4All scenarios: human wellbeing on a finite planet towards 2100 by Per Espen Stoknes, David Collste, Sarah E. Cornell, Ben Callegari, Nathalie Spittler, Owen Gaffney, Jorgen Randers

“…We have developed scenarios that explore interconnections between possible climate futures, rising living costs, and increasing inequalities that fuel populism and undermine democracy to the year 2100. …”
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Comparison of Knowledge and Practice of Mothers of Children with Febrile Convulsion with or without Recurrence by Maryam Rostami Ghadi, Seyedeh Zahra Shafipoor, Reyhaneh Fadakar, Elham Bidabadi, Ehsan KazemnejadLeili, Somaye Shirkosh

“…Due to the high prevalence of febrile seizures, the need to conduct a study to determine the knowledge and practice of mothers of children with and without recurrence seemed necessary and by identifying these factors, prevention of future attacks, its complications and high costs of treatment, an effective step can be taken to improve children's health. …”
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The usage of imidazolinone-tolerant maize in maize-soybean strip intercropping greatly facilitates weed control by Yue Zhao, Atta Mohi Ud Din, Muhammad Ali Raza, Wenyu Yang, Jialin Yu, Xing Wang Deng, Lingyang Feng

“…Moreover, NSW increased weeding speed by fivefold, reduced herbicide and spraying costs by $37.05 USD ha-1, and enhanced net benefits by 58%, reaching $3414.12 USD ha-1. …”
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What is the care economy? A scoping review on current evidence, challenges, facilitators and future opportunities by I. Blackberry, I. Blackberry, J. Boak, J. Boak, K. Barclay, H. Khalil, H. Khalil

“…Barriers to providing care were lack of education, support and monitoring of caregiver well-being, loss of income or ability to earn money, reduced social life and increased out-of-pocket costs. Gaps in research included migrant populations’ contribution to the care economy, gender and diversity inequality in the care economy. …”
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Use of Artificial Intelligence, Internet of Things, and Edge Intelligence in Long-Term Care for Older People: Comprehensive Analysis Through Bibliometric, Google Trends, and Conten... by Shuo-Chen Chien, Chia-Ming Yen, Yu-Hung Chang, Ying-Erh Chen, Chia-Chun Liu, Yu-Ping Hsiao, Ping-Yen Yang, Hong-Ming Lin, Tsung-En Yang, Xing-Hua Lu, I-Chien Wu, Chih-Cheng Hsu, Hung-Yi Chiou, Ren-Hua Chung

“… BackgroundThe global aging population poses critical challenges for long-term care (LTC), including workforce shortages, escalating health care costs, and increasing demand for high-quality care. …”
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Bifurcation analysis of multistability and hysteresis in a model of HIV infection by I. V. Mironov, M. Yu. Khristichenk, Yu. M. Nechepurenko, D. S. Grebennikov, G. A. Bocharov

“…The current approach to HIV-1 treatment is based on the use of highly active antiretroviral therapy, which has side effects and is costly. For clinical practice, it is highly important to create functional cures that can enhance immune control of viral growth and infection of target cells with a subsequent reduction in viral load and restoration of the immune status. …”
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Quantification of Phenolic Compounds in Olive Oils by Near-Infrared Spectroscopy and Multiple Regression: Effects of Cultivar, Hydroxytyrosol Supplementation, and Deep-Frying by Taha Mehany, José M. González-Sáiz, Consuelo Pizarro

“…Implementing an NIR instrument with optimized variable selection would simplify spectral analysis and reduce costs. The developed models all demonstrated strong predictive performance, with low leave-one-out mean prediction errors (LOOMPEs) with values of 15.69, 8.47, 3.64, 9.18, 16.71, 3.26, 8.57, 13.56, 56.36, and 82.38 mg/kg for HTyr, Tyr, caffeic acid, oleocanthal, oleacein, homovanillic acid, pinoresinol, OAOAH, LAOAH, and TPC, respectively. …”
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Smart diabetes management: remote monitoring and predictive health insights by K.S. Smelyakov, I.A. Lurin, K.V. Misiura, A.S. Chupryna, T.V. Tyzhnenko, O.D. Dolhanenko, V.M. Repikhov

“…The article also addresses the challenges in Ukraine’s healthcare system, especially for diabetes patients in economically disadvantaged or rural areas, where access to CGMs and insulin pumps is limited due to high costs. Despite these challenges, progress is being made through public health initiatives, mobile health apps, and government support programs aimed at increasing awareness and access to care. …”
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Evaluation of Blast Resistance in Zinc-Biofortified Rice by Anita Nunu, Maina Mwangi, Nchore Bonuke, Wagatua Njoroge, Mwongera Thuranira, Emily Gichuhi, Ruth Musila, Rosemary Murori, Samuel K. Mutiga

“…Breeding for resistance can help farmers avoid costly fungicides. This study assessed the relationship between rice blast disease and zinc or anthocyanin content in biofortified rice. …”
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Association of Mobile Stroke Unit Care and Spending, Utilization, and Death in New York City by Dhruv Khullar, Babak B. Navi, Saad Mir, Matthew E. Fink, Luisa Tinapay, Glenn Asaeda, Rainu Kaushal, Eshani Pareek, Amelia M. Bond

“…Primary outcomes included length of stay and discharge destination at the index hospitalization, as well as risk of repeat hospitalization, number of emergency department visits, total costs of care, and death at 1 year. Of 167 patients (mean age, 79.9 years; 56.3% women) transported by an MSU for suspected acute stroke, 61.1% had an ischemic stroke/transient ischemic attack, 7.8% had an intracerebral hemorrhage, and 31.1% had a stroke mimic or other diagnosis. …”
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Question–Answer Methodology for Vulnerable Source Code Review via Prototype-Based Model-Agnostic Meta-Learning by Pablo Corona-Fraga, Aldo Hernandez-Suarez, Gabriel Sanchez-Perez, Linda Karina Toscano-Medina, Hector Perez-Meana, Jose Portillo-Portillo, Jesus Olivares-Mercado, Luis Javier García Villalba

“…Traditional static and dynamic analysis techniques, although widely used, often exhibit high false-positive rates, elevated costs, and limited interpretability. Machine Learning (ML)-based approaches aim to overcome these limitations but encounter challenges related to scalability and adaptability due to their reliance on large labeled datasets and their limited alignment with the requirements of secure development teams. …”
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Diagnostic accuracy of the Panbio COVID-19 antigen rapid test device for SARS-CoV-2 detection in Kenya, 2021: A field evaluation. by Jack Karuga Irungu, Peninah Munyua, Caroline Ochieng, Bonventure Juma, Patrick Amoth, Francis Kuria, John Kiiru, Lyndah Makayotto, Ahmed Abade, Marc Bulterys, Elizabeth Hunsperger, Gideon O Emukule, Clayton Onyango, Taraz Samandari, Beth A Tippett Barr, Victor Akelo, Herman Weyenga, Patrick K Munywoki, Godfrey Bigogo, Nancy A Otieno, Jackton Azenga Kisivuli, Edwin Ochieng, Rufus Nyaga, Noah Hull, Amy Herman-Roloff, Rashid Aman

“…The reference standard, rRT-PCR, requires specialized laboratories, costly reagents, and a long turnaround time. Antigen RDTs provide a feasible alternative to rRT-PCR since they are quick, relatively inexpensive, and do not require a laboratory. …”
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Optimizing Cardiovascular Risk Management in Primary Care Using a Personalized eCoach Solution Enhanced by an Artificial Intelligence–Driven Clinical Prediction Model: Protocol fro... by Rutger van Mierlo, Bart Scheenstra, Joost Verbeek, Anke Bruninx, Petros Kalendralis, Inigo Bermejo, Andre Dekker, Arnoud van 't Hof, Marieke Spreeuwenberg, Laura Hochstenbach

“… BackgroundAtherosclerotic cardiovascular disease poses a heavy burden on the population’s health and health care costs. Identifying apparently healthy individuals at risk of developing cardiovascular diseases using clinical prediction models raises awareness, facilitates shared decision-making, and supports tailored management of disease prevention. …”
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