AI‐assisted warfarin dose optimisation with CURATE.AI for clinical impact: Retrospective data analysis by Tiffany Rui Xuan Gan, Lester W. J. Tan, Mathias Egermark, Anh T. L. Truong, Kirthika Kumar, Shi‐Bei Tan, Sarah Tang, Agata Blasiak, Boon Cher Goh, Kee Yuan Ngiam, Dean Ho

“…CURATE.AI may facilitate the effective use of affordable warfarin with a well‐established safety profile, without the need for costly, new oral anticoagulants. This can have significant impact both on the individual and public health.…”
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Transitioning apple farming towards sustainability: evidence from Himachal Pradesh, India by Divyanshu, Rohit Kumar Vashishat, Subhash Chander Verma, Rajeshwar Singh Chandel, Subhash Sharma, Sudhir Verma, Narender Bharat, Kuldeep Singh Thakur, Inder Dev, Sanjeev Chauhan, Prashant Sharma, Kamal Kishore, Ashu Chandel, Pramod Sharma

“…The Apple + Vegetables combination under NF resulted in a 31.29% increase in net returns and a 27.55% reduction in production costs, primarily due to the elimination of chemical inputs. …”
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Insurance Payor Status and Outcomes in Pediatric Sports-Related Injuries: A Rapid Review by Katherine M. Kutzer, Lulla V. Kiwinda, Daniel Yang, John Kyle Mitchell, Emily J. Luo, Emily J. Harman, Stephanie Hendren, Kendall E. Bradley, Brian C. Lau

“…<b>Introduction</b>: The rise in youth sports participation has led to an increase in pediatric sports-related injuries in the United States, contributing to growing healthcare costs and exacerbating socioeconomic disparities. …”
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Microbial contamination of unsterile vs sterilized 3M™ Micropore™ tape on full-thickness skin graft donor wound: Clinical trial and evaluation by Graciella Novian Triana Wahjoe Pramono, Betha E. Riestiano, Hardisiswo Soedjana, Leonardus Widyatmoko, Sandy Sopandi

“…Sterile tapes in developing countries are harder to find and more costly. Whether unsterile tape is safe to use on fresh wounds is an ongoing debate. …”
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Fatty acid biomarkers reveal the interaction between two highly migratory species in the Southern Humboldt System: the swordfish and its prey, the jumbo squid by Marco Quispe-Machaca, Fabián Guzmán-Rivas, Patricio Barría Martínez, Christian Ibáñez, Ángel Urzúa

“…In both species, a high bioenergetic fuel content characterized by a predominance of saturated, monounsaturated, and polyunsaturated fatty acids may be necessary to sustain the high energy costs involved in their migratory and reproductive processes in the Humboldt Current system.…”
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The resurgence of Lassa fever in Nigeria: economic impact, challenges, and strategic public health interventions by Stanley Chinedu Eneh, Stanley Chinedu Eneh, Stanley Chinedu Eneh, Chidera Gabriel Obi, Chidera Gabriel Obi, Udokang Ephraim Ikpongifono, Udokang Ephraim Ikpongifono, Zakariya’u Dauda, Zakariya’u Dauda, Samson Adiaetok Udoewah, Samson Adiaetok Udoewah, Collins Chibueze Anokwuru, Collins Chibueze Anokwuru, Francisca Ogochukwu Onukansi, Francisca Ogochukwu Onukansi, Ogechi Vinaprisca Ikhuoria, Ogechi Vinaprisca Ikhuoria, Temitope Olumuyiwa Ojo, Chukwuocha Uchechukwu Madukaku, Ibuchukwu Nkeonyenasoya Orabueze, Ibuchukwu Nkeonyenasoya Orabueze, Amara Frances Chizoba

“…The economic impact extends beyond healthcare costs to agricultural disruptions, trade restrictions, and workforce productivity losses. …”
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Unveiling the anticancer potential of SGLT-2 inhibitors: mechanisms and prospects in clinical oncology—a narrative review by Jiaxin Li, Jie Qiao, Shitong Zhang, Jianhua Zhong, Caiying Ke, Yiqi Lin, Yuetong Li, Ying Jin, Yaqi Yao, Aixia Zhai, Changlong Bi

“…Current cancer treatments are often costly and have long trial periods. Sodium-glucose cotransporter-2 inhibitors (SGLT-2is), including dapagliflozin and canagliflozin, were originally developed for blood glucose control, but have shown promise in anticancer applications. …”
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Use of the FINDRISC scale in the department of Cundinamarca, Colombia: A descriptive and cross-sectional study by Ramon A Castaño, Maria Angélica Granados, Angel F Maestre, Juan Felipe Trujillo-Angel, Constanza Neri Morales, Carlos Leal Bernal, Carlos Julio Corzo Diaz, Juan Pablo Bernal Soler, Natalia Trujillo, Juan Sebastian Cardona, Rossmary Gonzalez, Maria Alejandra Larrarte, Derly Carolina Hernandez, Patrizia Trasmondi, Noël Barengo, Humberto Reynales

“… Background: Type II diabetes (T2D) is a chronic disease with high rates of morbidity and mortality, which implies a great impact on the economy and health systems due to its high prevalence rates, complications, and costs. Prediabetes arises as an abnormal state that precedes type II diabetes and is associated with multiple risk factors. …”
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Harnessing machine learning to predict and prevent proximal junctional kyphosis and failure in adult spinal deformity surgery: A systematic review by Paolo Brigato, Gianluca Vadalà, Sergio De Salvatore, Leonardo Oggiano, Giuseppe Francesco Papalia, Fabrizio Russo, Rocco Papalia, Pier Francesco Costici, Vincenzo Denaro

“…Introduction: Adult spinal deformity (ASD) surgery involves high costs and risks, with Proximal Junctional Kyphosis (PJK) and Proximal Junctional Failure (PJF) being major concerns. …”
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Development and engineering application validation of alkali-activated full-component shield tunnel spoil regenerated solid-waste grouting material by Zhiran Yang, Yu Zhou, Li Wang, Shizhuo Zou, Jinfei Chai, Yufei Fang, Shichao Jiang, Hui Ma

“…To address the issues of high disposal costs and low resource recovery efficiency of shield tunnel spoil (STS), this study proposes an Alkali-Activated Full-Component Shield Tunnel Spoil Regenerated Solid-Waste Grouting Material (AFS-RSWGM). …”
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Performance and emission analysis of cotton seed biodiesel enhanced with nano-MgO as a sustainable fuel in a compression ignition engine by N. Murugu Nachippan, V. Balaji, Ganesan Subbiah, Ritesh Pratap Singh, Kamakshi Priya K, Aseel Smerat

“…A life cycle analysis (LCA), in conjunction with economic and environmental evaluations based on circular economy principles, confirmed the long-term sustainability and practicality of nano-magnesium oxide enhanced cottonseed biodiesel. Although production costs are higher due to the nano-additives, the gains in engine efficiency and reduced emissions justify the expense. …”
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Chloride-dependent plasma membrane hyperpolarization confers superior salinity tissue tolerance in wild rice Oryza coarctata by Ping Yun, Celymar Angela Solis, Babar Shahzad, Lana Shabala, Meixue Zhou, Gayatri Venkataraman, Zhong-Hua Chen, Sergey Shabala

“…It is concluded that O. coarctata possesses a strong ability to discriminate between Cl− and Na+ uptake (a trait lacking in cultivated rice) and use it to maintain negative membrane potential (MP) values without activating H+-ATPase, thus enabling more efficient K+ retention in mesophyll with low energy costs. The above traits should be considered as potential targets in the rice breeding program for salt tolerance enhancement.…”
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Pre- and Postoperative Risk Factors for Hirschsprung-Associated Enterocolitis in Vietnamese Children by Hoang Tran Viet, Tuan Huynh Minh, Nhan Vu Truong, Anh Huynh Thi Phuong, Bich-Uyen Nguyen, Hao Chung The, Cong Phi Dang, Linh Truong Nguyen Uy

“…<b>Background/Objective</b>: Hirschsprung-associated enterocolitis (HAEC) can occur before and after surgery, increasing the complication rates, hospital stay, and treatment costs. This study aims to determine the incidence of preoperative and postoperative Hirschsprung-associated enterocolitis HAEC and the related risk factors. …”
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Practical Quantum Circuit Implementation for Simulating Coupled Classical Oscillators by Natt Luangsirapornchai, Peeranat Sanglaor, Apimuk Sornsaeng, Stephane Bressan, Thiparat Chotibut, Kamonluk Suksen, Prabhas Chongstitvatana

“…Numerical simulations agree with classical solvers across all tested configurations, indicating that this circuit-based Hamiltonian simulation approach can substantially reduce computational costs and potentially enable larger-scale many-body studies on future quantum hardware.…”
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Dual targeting of BCMA and SLAMF7 with the CARtein system: chimeric antigen receptors with intein-mediated splicing elicit specific T cell activation against multiple myeloma by Noelia Moares, Noelia Moares, Pablo Gonzalez-Garcia, Pablo Gonzalez-Garcia, Wenjie Yi-He, Wenjie Yi-He, Juan P. Muñoz-Miranda, Juan P. Muñoz-Miranda, Antonio Gabucio, Antonio Gabucio, Rosa Luna-Espejo, Javier Ocaña-Cuesta, Ricardo Fernandez-Cisnal, Cecilia M. Fernandez-Ponce, Cecilia M. Fernandez-Ponce, Francisco Garcia-Cozar, Francisco Garcia-Cozar

“…However, several barriers continue to limit the overall effectiveness of this approach, such as high production costs, prolonged manufacturing timelines, safety issues, and the potential for tumor antigen escape due to selective therapeutic pressure. …”
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Usage of the mobile phone on agricultural farm enterprise development by women in rural Bangladesh by Md. Sadekur Rahman, Md. Enamul Haque, Md. Safiul Islam Afrad, Shaikh Shamim Hasan, Md. Abiar Rahman, Md. Rubayet Al Ferdous Noman

“…Factors such as reduced transportation costs, time-saving, easy contact with stakeholders, and frequent contact with fellow entrepreneurs were identified as significant influences on rural women’s mobile phone usage. …”
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Assessment of Winery By-Products as Ingredients as a Base of “3S” (Safe, Salubrious, and Sustainable) Fermented Beverages Rich in Bioactive Anthocyanins by Berta María Cánovas, Irene Pérez-Novas, Cristina García-Viguera, Raúl Domínguez-Perles, Sonia Medina

“…The lack of proper valorisation alternatives entails high disposal costs and resource inefficiency that jeopardise the sustainability and competitiveness of the industry. …”
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Patient preferences and shared decision making for the traditional Chinese medicine treatment of lung cancer: A discrete choice experiment study by Yue Teng, Yan Wei, Yingyao Chen, Juntao Yan, Shimeng Liu, Fuming Li, Shiyi Bao, Yanfeng Ren, Liu Liu, Yi Yang

“…Patients showed strong preferences for increasing disease control rate, relieving nausea and vomiting, reducing the risk of side effects, and were concerned about monthly out-of-pocket costs. Subgroup analysis indicated that patients with a lower SDM-Q-9 score and those who were satisfied with medical services emphasized more importance of higher disease control rate. …”
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Diagnostic performance and clinical utility of metagenomic next-generation sequencing in suspected central nervous system infections: a prospective comparative study by Xiao-guang Cao, Xiong-feng Zhu, Zha Yu, Chun-yan Wang, Min Shao, Hua-dong Meng, Chong-jian Huang

“…Compared to the non-infection group, patients with CNS infections had significantly higher ICU admission(ICUA) rates, prolonged hospital stays, increased healthcare costs, and elevated rates of antibiotic adjustment and mNGS positivity (P&lt;0.05). …”
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Exploring the evolution of hollow fiber membrane applications in wastewater treatment by Fulufhelo H. Mudau, Zebron Phiri, Machawe M. Motsa, Lueta-Ann de Kock

“…Despite these advances, challenges such as membrane fouling, high operational costs, and limited scalability persist. Furthermore, integrating HFMs with pretreatment technologies and developing novel materials are pivotal for minimizing fouling and enhancing operational performance across various wastewater types. …”
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