RMDNet: RNA-aware dung beetle optimization-based multi-branch integration network for RNA–protein binding sites prediction by Jiangbo Zhang, Yunhui Peng, Feifei Cui, Zilong Zhang, Shankai Yan, Qingchen Zhang

“…Although experimental methods like CLIP-seq accurately identify RNA–protein binding sites, they are time-consuming and costly. To address this, we propose RMDNet—a deep learning framework that integrates CNN, CNN-Transformer, and ResNet branches to capture features at multiple sequence scales. …”
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Machine learning-based model for behavioural analysis in rodents applied to the forced swim test by Andrea Della Valle, Sara De Carlo, Gregorio Sonsini, Sebastiano Pilati, Andrea Perali, Massimo Ubaldi, Roberto Ciccocioppo

“…Despite eliminating some biases, existing automated systems are costly and typically only able to distinguish between immobility and active behaviours. …”
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Pharmacokinetic Equations Applied to Obtain New Topological Models in the Search of Antibacterial Compounds by Jose I. Bueso-Bordils, Gerardo M. Antón-Fos, Rafael Martín-Algarra, Pedro A. Alemán-López

“…This elevated resistance is associated with expanded morbidity and mortality, as well as an increase in healthcare costs. The development of new molecules with antibacterial activity is therefore urgently needed. …”
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Bacteriological Spectrum and Drug Resistance Among Patients Associated With Bloodstream Infection in Intensive Care Units in the Affiliated Hospital of Jiaxing University From 2021... by Yucheng Xie, Xiaochun Tan, Wei Wang, Bailong Hou, Minjie Mao, Xiaoqin Niu, Qinlong Yu, Weifeng Shen

“…Bloodstream infections (BSI) in ICU settings are associated with high morbidity, mortality, and healthcare costs. The ICU environment, with its high use of invasive devices and immunocompromised patients, fosters an increased risk for multidrug resistance (MDR) pathogens, complicating treatment strategies. …”
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Features of Learning Strategies, Barriers and Motivation of Chinese Students in Russian-Speaking Environment and in China by Natalya S. Brem, Elena M. Dubrovskaya

“…There have been numerous studies to investigate the role of language immersion in foreign language learning considering corresponding financial and time costs. The objective of the current study was to investigate the influence of the language environment on: motivation, learning barriers, and learning strategies. …”
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Early clinical outcomes using a 6.3 Fr single use ureteroscope compared to a 7.5 Fr device by Petrisor-Aurelian Geavlete, Catalin-Andrei Bulai, Razvan-Dragos Multescu, Cosmin-Victor Ene, Adrian Militaru, Ana-Maria Andreea Punga, Bogdan-Florin Geavlete

“…The emergence of single-use ureteroscopes addresses challenges associated with reusable devices, such as cross-contamination, maintenance costs, and degradation over time. This prospective, single-center study compared the performance of the 6.3 Fr single-use flexible ureteroscope to the 7.5 Fr model in the treatment of kidney stones ≤ 2 cm. …”
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An automated in-field transport and imaging chamber system for high-throughput phenotyping of potted soybean by Xiuni Li, Menggen Chen, Shuyuan He, Mei Xu, Yao Zhao, Weiguo Liu

“…This expands trait detection capacity while reducing costs for reuse and secondary development. Conclusion This study demonstrated the feasibility of combining natural field conditions with standardized indoor imaging for phenotypic research on soybeans under vertical planting systems. …”
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Nutrigenomic and Nutritional Analyses Reveal the Effects of Pelleted Feeds on Asian Seabass (Lates calcarifer). by Si Yan Ngoh, Daniel Tan, Xueyan Shen, Purushothaman Kathiresan, Junhui Jiang, Woei Chang Liew, Natascha May Thevasagayam, Hsiao Yuen Kwan, Jolly M Saju, Sridatta R S Prakki, Chin Heng Goh, Hong Ching Wong, Tai Teck Chan, Miklós Mézes, László Orbán

“…As nutrition-related expenses constitute the majority of the costs for aquaculture farms, it is essential for them to use feeds that provide an ideal combination of nutrients for the species of choice. …”
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The Application and Ethical Implication of Generative AI in Mental Health: Systematic Review by Xi Wang, Yujia Zhou, Guangyu Zhou

“… BackgroundMental health disorders affect an estimated 1 in 8 individuals globally, yet traditional interventions often face barriers, such as limited accessibility, high costs, and persistent stigma. Recent advancements in generative artificial intelligence (GenAI) have introduced AI systems capable of understanding and producing humanlike language in real time. …”
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Mechanism Operation for Changing the Rear Axle Clearance of a Universal Row-crop Tractor by A. A. Akhmetov, Sh. A. Akhmedov, B. Zh. Astanov, D. U. Kambarova, R. M. Botirov

“…(Materials and methods) The authors showed that the rear axle clearance could be changed using a special mechanism - with minimal labor costs, without the use of lifting equipment and assembly and dismantling works. …”
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Effects of early factor XIII replacement in postpartum hae morrhage: study protocol for a multicentre, open-label, randomised, controlled, investigator-initiated trial by Torsten Hothorn, Christian Haslinger, Verena Bossung, Stylianos Kalimeris, Elisabetta Ranieri, Nicole Ochsenbein-Koelble, Wolfgang Korte

“…A preliminary overview on costs and potential savings through early treatment of PPH with FXIII is included in the analysis as well as a patient and public involvement report, asking for patients’ personal experience during PPH in the main study centre.Ethics and dissemination Ethics approval was granted by the central ethics committee (Kantonale Ethikkommission Zürich/Switzerland) on 16 June 2024, reference number: BASEC 2024-00374. …”
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Luminescent materials based on organic salts pyrolyzed at the silica surface by P. O. Kuzema, Yu. M. Bolbukh, V. A. Tertykh

“…Most of the synthetic methods are still relatively complex and costly. Here, the simple and inexpensive route to produce luminescent silica-based nanomaterials was used. …”
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Enzymatic hydrolysis of high gravity extruded corn starch media by A. Yu. Sharikov, M. V. Amelyakina, V. V. Ivanov, D. V. Polivanovskaya

“…It promotes the reduction in operating costs, in heat and energy consumption and increases the efficiency of using capacitive equipment. …”
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Relapse and associated factors among psychiatric patients in Africa: a systematic review and meta-analysis by Belete Birhan, Gidey Rtbey, Kelemu Abebe Gelaw

“…This phenomenon can adversely affect the prognosis of the disorder, the functionality of individuals, and may even increase the overall costs of treatment. To achieve the desired outcomes in psychiatric treatment, it is crucial to prevent relapse whenever possible. …”
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Optimizing appliance scheduling for utility and budget in smart energy systems under inclining block rate tariffs by Ahmed Shaban, Mohamed Salhen, Mohamed A. Shalaby, Tamer F. Abdelmaguid

“…Smart energy management is critical for reducing household electricity costs and addressing rising demand. While appliance scheduling is often explored under dynamic pricing schemes, this study demonstrates its effectiveness under Inclining Block Rate (IBR) tariffs—commonly used in developing countries and currently applied in Egypt. …”
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Plasma/Serum Electrolyte and Metabolite Testing on Blood Gas Analyzer ABL837, a New Application by Vera Y. Chen, Rachel Fullarton, Yu Chen

“…<b>Background</b>: Core laboratory chemistry analyzers typically use plasma and serum samples, while blood gas instruments use whole blood for electrolyte and metabolite tests. Due to high costs to back up the core lab chemistry analyzers, especially in the remote small community hospitals, we have verified the interchangeability of serum/plasma electrolytes and metabolites on blood gas instruments (GEM4000 and Radiometer ABL90) vs. chemistry analyzers. …”
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Analysis of real-time energy transfer possibilities at intersections with consideration of energy storage by Marcin Koniak, Piotr Jaskowski, Radovan Madleňák, Jurijus Zaranka

“…The final choice of energy storage technology will depend on local conditions, such as space availability, investment costs, and market availability. …”
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Developing a Prediction Model for Real-Time Incident Detection Leveraging User-Oriented Participatory Sensing Data by Md Tufajjal Hossain, Joyoung Lee, Dejan Besenski, Branislav Dimitrijevic, Lazar Spasovic

“…Traditional methods relying on stationary technologies are often costly and provide limited coverage, prompting the exploration of crowdsourced data such as Waze. …”
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Modelling the fatigue damage in power components using machine learning technology by Stoyan Stoyanov, Razia Sulthana, Tim Tilford, Xiaotian Zhang, Yihua Hu, Xingyu Yang, Yaochun Shen, Yangang Wang

“…However, from an end-user point of view, the deployment of such high-fidelity modelling is not straightforward as it requires comprehensive device and material characterisation data that is not readily available through technical datasheets and must be gathered using costly and time-consuming bespoke characterisation tests and access to metrology instruments. …”
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Innovative Technologies and Technical Means for Industrial Nursery Farming by A. A. Zavrazhnov, A. Yu. Izmaylov, A. I. Zavrazhnov, Ya. P. Lobachevskiy, V. Yu. Lantsev

“…The use of high-level technical means of SUVES, VP-1.5 and AP-1.5 with replaceable technological modules increases the level of mechanization by an average of 30 percent, signifi cantly reduces labor costs – up to 20 percent, and improves working conditions for operating staff .…”
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