Bioactive protein hydrolysate from Sesamum indicum L. residue as a novel fat substitute by protease: production optimization and application in low-fat yogurt production by Samia A. Ahmed, Mohamed A. A. Abdella, Osama A. Ibrahim

“…Therefore, transforming these residues to eco-friendly products such as enzymes and bioactive materials reduces their quantity and impact on the environment, in addition to reducing the production costs. Results Sesame cake is a by-product of the production of Sesame seed oil and is high in protein. …”
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Determination of Fast-Moving Objects’ Speed and Range with Linear Frequency Modulation Continuous Wave Radar Using Autocorrelation Scheme by N. V. Sokolik

“…Its usage allows one to improve the stability of the algorithm without considerable additional computational costs. It is possible because near-linear dynamics of the observation object and of the radar carrier makes it sufficient to use a simplified implementation of Kalman filter in the form α-β-algorithm.…”
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Practices and attitudes of dentists regarding the use and phase-out of dental amalgam fillings: compliance with EU regulations and the Minamata Convention by Vanja Usenik, Davor Kontić, David Kocman, Milena Horvat

“…Amalgam use varied the most in adult clinics, influenced by clinical needs, patient preferences, and systemic barriers related to reimbursing costs for alternative materials not covered by health insurance until recently. …”
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Hash-Guided Adaptive Matching and Progressive Multi-Scale Aggregation for Reference-Based Image Super-Resolution by Lin Wang, Jiaqi Zhang, Huan Kang, Haonan Su, Minghua Zhao

“…This not only retains global modeling capabilities, but also significantly reduces computational costs. In addition, a learnable similarity scoring function has been designed to adaptively optimize the similarity score between LR images and Ref images, improving matching accuracy. …”
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Comparative Analysis of Characteristic Parameters of Supercritical Water-Cooled Reactor and Molten Salt Reactor by Pingxun ZHANG, Bo LIU, Xiaoze ZHAO

“…[Objective] The concept designs of the six types of reactors, proposed by the Generation Ⅳ International Forum (GIF), aim to significantly reduce the generation of nuclear waste, fully utilize uranium resources, and lower the construction and operating costs of nuclear power. As candidate reactor types, supercritical water-cooled reactors and molten salt reactors have garnered positive attention from various countries owing to their high safety, cleanliness, and efficiency advantages. …”
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Understanding the layout of emergency scientific research during COVID-19 prevention and control: a comparative analysis of project solicitation and project approval by Jida Liu, Yuxin Wang, Yuwei Song, Qiaoqiao Li

“…Abstract Background Emergency scientific research (ESR) is characterized by multidisciplinary integration, multidemand matching, and multiscenario application, which impose greater applicability requirements and tolerance for costs than conventional scientific research does. …”
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Nature positive farm dams by K.U.D.N. Hansani, Lukas Schuster, Peter I. Macreadie, Martino E. Malerba

“…Integrating carbon or biodiversity crediting for direct and indirect ecosystem services associated with nature positive farm dams is a promising solution for reducing the costs of sustainable farm dam management.…”
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Primary healthcare providers’ perspectives on six-month dispensing of antiretroviral therapy (ART) in South Africa: cross-sectional survey of views and preferences by Vinolia Ntjikelane, Amy Huber, Allison Morgan, Sophie Pascoe, Musa Manganye, Lufuno Malala, Sydney Rosen

“…More than 80% of respondents across all cadres reported that they would be comfortable dispensing 6 months of ART at a time, believing that it would reduce the facility overcrowding, lighten staff workloads, and be advantageous to clients by decreasing their visit burden and travel costs. Two thirds (63%) of participating nurses, who provide the largest share of direct ART care, were also in favour of resuming 12-month scripting for ART; the remaining 37% expressed concerns about decreases in treatment adherence and clinical monitoring of clients. …”
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The effects of cognitive therapy versus 'treatment as usual' in patients with major depressive disorder. by Janus Christian Jakobsen, Jane Lindschou Hansen, Ole Jakob Storebø, Erik Simonsen, Christian Gluud

“…<h4>Background</h4>Major depressive disorder afflicts an estimated 17% of individuals during their lifetimes at tremendous suffering and costs. Cognitive therapy may be an effective treatment option for major depressive disorder, but the effects have only had limited assessment in systematic reviews.…”
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Planejamento do controle estatístico de processos com baixa fração não conforme restrito a amostras pequenas Design of the statistical control of low fraction nonconforming process... by Eugenio Kahn Epprecht, Adriana Leiras, Antonio Fernando Branco Costa

“…<br>We present the non-conventional design of np charts used for the surveillance of processes characterized by a very low fraction nonconforming, with a costly and/or time-consuming inspection procedure, which makes the inspection of large samples prohibitive. …”
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Review of the Role of Heat Pumps in Decarbonization of the Building Sector by Agnieszka Żelazna, Artur Pawłowski

“…Despite higher investment costs, the lower environmental footprint of GSHPs and WSHPs makes them attractive options for decarbonizing the building sector due to better performance resulting from more stable thermal input and higher SCOP. …”
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Understanding the relationship between education-based hypergamy and women's social interaction in China: mediating roles of career aspirations and social distrust by Penghui Wu, Ming Zhang, Senhao Xiong

“…The dynamics of traditional gender norms and opportunity costs of balancing career and household duties present barriers to SI for these women. …”
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Radar Method for Obtaining Information from a Horizontal Directional Drilling Device by A. V. Vagin, A. S. Vorotyntseva

“…The radar method for obtaining such information allows the drilling process to be optimized by increasing the positioning accuracy, providing for constant automatic position monitoring, as well as reducing the time and financial costs.Aim. To demonstrate the possibility of constructing a radar complex for obtaining information about positioning of the drilling head of a directional drilling installation based on transponder beacons distributed on the surface of the earth.Materials and methods. …”
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Deep Learning-Based Vertical Decomposition of Ionospheric TEC into Layered Electron Density Profiles by Jialiang Zhang, Jianxiang Zhang, Zhou Chen, Jingsong Wang, Cunqun Fan, Yan Guo

“…This method overcomes the reliance of traditional electron density inversion on costly radar or satellite observations, enabling high-spatiotemporal-resolution global ionospheric profile reconstruction using widely available GNSS-TEC data. …”
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Leveraging AlphaFold2 structural space exploration for generating drug target structures in structure-based virtual screening by Keisuke Uchikawa, Kairi Furui, Masahito Ohue

“…Computational virtual screening (VS) plays a vital role in early-stage drug discovery by enabling the efficient selection of candidate compounds and reducing associated costs. However, the absence of experimentally determined three-dimensional protein structures often limits the applicability of structure-based VS. …”
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Functional discrimination of CSF from Alzheimer’s patients in a brain on chip platform by Louise Miny, Jessica Rontard, Ahmad Allouche, Nicolas Violle, Louise Dubuisson, Aurélie Batut, Alexandre Ponomarenko, Rania Talbi, Hélène Gautier, Benoît G. C. Maisonneuve, Serge Roux, Florian Larramendy, Thibault Honegger, Isabelle Quadrio

“…Abstract Neurodegenerative diseases, including Alzheimer’s disease (AD), present significant diagnostic challenges due to overlapping symptoms and the invasive, time-consuming, and costly nature of current diagnostic methods. While AD remains the only neurodegenerative disorder for which biomarkers in cerebrospinal fluid (CSF), such as amyloid beta peptide (Aβ), are available for clinical diagnosis, similar tools are lacking for other neurodegenerative conditions. …”
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Groundwater in Germany: challenges, solutions, and the BMBF funding measure LURCH: sustainable groundwater management by Sarah Fieger, Thomas Track

“…Additionally, sustainable management strategies consider economic feasibility, investment, and operating costs, supported by digital tools for improved decision-making. …”
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Bedside implications of the use of surrogate endpoints in solid and haematological cancers: implications for our reliance on PFS, DFS, ORR, MRD and more by Vinay Prasad, Alyson Haslam, Timothée Olivier, Dagney Ochoa, Eduardo Fernandez

“…In liquid malignancies, surrogates can mislead us to use novel drugs and replace proven standards of care with costly medications. Surrogates can lead one to intensify treatment without clear improvement and possibly worsening quality of life. …”
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Management of business processes of a commercial enterprise in the conditions of digitalization by K.O. Buzhymska, I.M. Tsaruk

“…On the basis of the presented scientific generalization, the value of digitalization in the business process management system of trade enterprises was characterized and it was determined that the introduction of digital technologies allows automating routine processes, reducing costs and speeding up the execution of tasks. Through data analysis, companies can better understand customer needs, optimize product assortments, and improve marketing strategies. …”
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Coagulation forceps-sparing techniques for pre-emptive sealing of blood vessels during third-space endoscopy by Zaheer Nabi, MD, DNB, FASGE, FISG, FSGEI, Pradev Inavolu, MD, DM, Rajesh Goud, PhD, Santhosh Darisetty, MD, D. Nageshwar Reddy, MD, DM

“…Although coagulation forceps can be used to effectively manage large blood vessels, their use necessitates frequent instrument exchanges, disrupting procedural flow and increasing costs. This review describes several distinct coagulation techniques to achieve coagulation without the need for hemostatic forceps. …”
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