Optimizing longifolene production in Yarrowia lipolytica via metabolic and protein engineering by Yi-Tong Yao, Xiao Zhang, Chen-Yu Wang, Yu-He Zhang, Da-Wei Li, Wei-Dong Yang, Hong-Ye Li, Li-Gong Zou

“…Traditional extraction methods from plants suffer from low titer and lengthy production cycles, while chemical synthesis is hampered by the compound's complex structure, leading to high costs and insufficient market supply. This study aimed to develop a microbial cell factory for enhanced longifolene production. …”
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Transfer learning and the early estimation of single-photon source quality using machine learning methods by David Jacob Kedziora, Anna Musiał, Wojciech Rudno-Rudziński, Bogdan Gabrys

“…Such a process is typically slow and costly, which has motivated growing research into whether SPS quality can be more rapidly inferred from incomplete emission statistics. …”
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Applications of bioactive herbal extracts in dressing materials for skin wound repair: Ingredients, mechanisms and innovations by Boxiang Yang, Jingyuan Xu, Siyi Liu, Chaoying Wu, Yi Li, Mingqi Lv, Tingting Chen, Chuanrong Zhao, Daojun Pu, Chaojun Tang, Anna Malashicheva, Guangchao Zang, Guixue Wang

“…Traditional treatments, while often effective, can be costly and pose risks. Herbal remedies offer a promising alternative given their rich history of use and multitarget therapeutic actions. …”
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Molecular identification of Giardia spp. in Latin America: An updated systematic review on reports from 2017 to 2021 by Yohanna Sarria-Guzmán, Yosef Chávez-Romero, Jaime Eduardo Bernal, Francisco Erik González-Jiménez, Nancy Serrano-Silva, Carmine Fusaro

“…Studies are also needed to estimate the costs of Giardiosis on economic productivity and public health. …”
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Sleep Apnea Events Recognition Based on Polysomnographic Recordings: A Large-Scale Multi-Channel Machine Learning approach by Nicolo La Porta, Stefano Scafa, Michela Papandrea, Filippo Molinari, Alessandro Puiatti

“…Such acquisition protocol requires dedicated facilities resulting in high costs and long waiting lists. The usage of artificial intelligence models assists the clinician's evaluation overcoming the aforementioned limitations and increasing healthcare quality. …”
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Mining privacy-preserving association rules using transaction hewer allocator and facile hash algorithm in multi-cloud environments by D. Dhinakaran, S. Gopalakrishnan, D. Selvaraj, M.S. Girija, G. Prabaharan

“…It also exhibits approximately 15 % reduction in communication costs and displays scalability with the growing number of transactions, compared to the state-of-the-art evaluation metrics that indicate improved communication overhead. • Introduces a multi-cloud privacy framework with Facile Hash Algorithm and Transaction Hewer and Allocator. • Enhances scalability using ATid algorithm with Tid Reduction.…”
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RT-DETR-Pro: An Enhanced RT-DETR Model for Visual Detection of Photovoltaic Module Defects by Yunliang Chen, Mingtao Shan, Wei Zhou, Bing Ma, Xun Mei

“…Secondly, an improved neck feature fusion strategy is adopted, which not only improves feature representation capability but also reduces computational costs and model complexity. Finally, a PV module image dataset is constructed using production line data from a PV module production factory. …”
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Optimal Allocation of Shared Energy Storage in Low-Carbon Parks Taking into Account the Uncertainty of Photovoltaic Output and Electric Vehicle Charging by Shang Jiang, Jiacheng Li, Wenlong Shen, Lu Liang, Jinfeng Wu

“…The results demonstrate that the proposed method can effectively mitigate the negative impact of source-load fluctuations, significantly reduce operating costs, and enhance carbon emission reductions. This study provides strong methodological support for optimal energy storage planning and low-carbon operation in park-level PV-SESS-CS.…”
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Variability of polymer for determination of soil-water characteristic curves by Gerarldo Davin Aventian, Alfrendo Satyanaga, Anar Arinova, Gulnur Kalimuldina, Sung-Woo Moon, Jong Kim

“…Nevertheless, acquiring accurate soil suction values remains challenging due to limitations in existing methodologies, such as susceptibility to cavitation, high costs, and time-intensive procedures. Hence, this study employs a high-suction polymer sensor (HSPS) to evaluate the polymer's performance in determining soil suction. …”
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Current trends in the treatments of choledochal cysts in pediatric patients in Korea in the era of minimally invasive surgery: narrative review by Ayoung Kang, Soo-Hong Kim, Hae-Young Kim

“…The surgical outcomes of robotic surgery are similar, but with challenges such as longer operation times, difficulties in small patients, and higher costs. Although laparoscopic surgery is currently the standard treatment in Korea, robotic surgery may become another standard procedure if the technological limitations can be overcome.…”
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Therapeutic potential of recombinant IL-22BP in psoriasis: suppression of IL-22/STAT3 signaling in mice by Xiuze Chen, Tao Zeng, Fang Fang, Qinyu Tian, Yingying Li, Wenlin Zhou, Binqian Gong, Na Tian, Jizhou Zhang, Yechen Xiao

“…Traditional IL-22BP production methods predominantly rely on eukaryotic animal cell expression systems, which generally require complex processes, resulting in low yield and high production costs. This study reports the expression of long-acting IL-22BP with a high yield and purity over 90% in Escherichia coli by fusion with the albumin-binding structural domain ABD. …”
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Advances and prospects for treatment strategies of drug-resistant tuberculosis: a review by Michalik, Maciej, Lorenc, Tomasz, Marcinkowski, Krzysztof, Muras, Mateusz, Mikszta, Natalia, Mikszta, Jakub, Kantor, Karolina, Marcinkowska, Julia

“…The treatment of DR-TB has been complicated by long regimens, severe side effects and high overall costs, which contribute to non-adherence and treatment failures. …”
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Time-course of antipredator behavioral changes induced by the helminth Pomphorhynchus laevis in its intermediate host Gammarus pulex: the switch in manipulation according to parasi... by Rigaud, Thierry, Balourdet, Aude, Bauer, Alexandre

“…Here we show that the protective part of this manipulation begins quite late during the parasite ontogeny, suggesting that the advantages overpass the costs induced by this protective manipulation only at this stage. …”
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The Application of Microsatellite Markers as Molecular Tools for Studying Genomic Variability in Vertebrate Populations by Roman O. Kulibaba, Kornsorn Srikulnath, Worapong Singchat, Yuriy V. Liashenko, Darren K. Griffin, Michael N. Romanov

“…Robust lab-based molecular technologies are supplemented by high-quality statistics and bioinformatics and have been widely employed, especially in those instances when more costly, high throughput techniques are not available. …”
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Effect of densification pretreatment on combustion and particulate matter emission characteristics of agricultural biomass by Wei Yang, Shilong Feng, Yongming Xu, Youjian Zhu, Shanzhi Xin, Wenbo Hu, Heyong Li, Pan Li, Huihui Liu, Haiping Yang

“…Agricultural biomass production in China is substantial, and the densification pretreatment of agricultural biomass has the potential to reduce usage costs and increase fuel energy density. However, there is still uncertainty regarding the impact of densification pretreatment on combustion characteristics and particulate matter emissions. …”
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DiffuseGaitNet: Improving Parkinson’s Disease Gait Severity Assessment With a Diffusion Model Framework by Arshak Rezvani, Nasrin Ravansalar, Mohammad Ali Akhaee, Andrew J. Greenshaw, Russell Greiner, Maryam S. Mirian, Muhammad Yousefnezhad, Martin J. McKeown

“…Assessing the severity of gait impairment in Parkinson’s disease (PD) using the Movement Disorder Society’s Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) is typically performed by clinical experts, but this process is time-consuming, subjective, and costly. To address these challenges, we propose a Guided Diffusion Model with an encoder-only transformer that automatically predicts gait severity by learning the underlying distribution of PD gait and leveraging domain knowledge critical for clinical evaluations. …”
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MPVT: An Efficient Multi-Modal Prompt Vision Tracker for Visual Target Tracking by Jianyu Xie, Yan Fu, Junlin Zhou, Tianxiang He, Xiaopeng Wang, Yuke Fang, Duanbing Chen

“…However, this approach suffers from low transfer learning efficiency, catastrophic forgetting, and high cross-task deployment costs. To address these issues, we propose an efficient model named multi-modal prompt vision tracker (MPVT) based on an efficient prompt-tuning paradigm. …”
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Integrating IT and OT for Cybersecurity: A Stochastic Optimization Approach via Attack Graphs by Gonzalo Martinez Medina, Krystel K. Castillo-Villar, Tanveer Hossain Bhuiyan

“…The defense strategies identified by our approach demonstrate that robust security protection can be achieved with optimal resource allocation, providing robust protection while minimizing implementation costs across the most critical vulnerabilities in the manufacturing network.…”
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A Novel Phase Error Estimation Method for TomoSAR Imaging Based on Adaptive Momentum Optimizer and Joint Criterion by Muhan Wang, Silin Gao, Xiaolan Qiu, Zhe Zhang

“…Compared to conventional phase error calibration methods in a two-step iterative framework, our proposed method considers image features and parameter coupling relationships, thus achieving higher precision estimation while saving computational costs. Finally, we demonstrate the effectiveness and applicability of the proposed method based on simulation experiments and real data experiments of the SARMV3D dataset.…”
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A 3.3 kV SiC Semi-Superjunction MOSFET with Trench Sidewall Implantations by Marco Boccarossa, Kyrylo Melnyk, Arne Benjamin Renz, Peter Michael Gammon, Viren Kotagama, Vishal Ajit Shah, Luca Maresca, Andrea Irace, Marina Antoniou

“…These results underscore the potential of tilted trench SSJ designs to significantly enhance the performance of SiC SSJ MOSFETs for high-voltage power electronics while simplifying fabrication and lowering costs.…”
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