Use of angiotensin receptor – neprilysin inhibitors in heart failure: a paradigm shift by M. O.E. Irhuma, M. Vally

“…Heart failure is a clinical syndrome responsible for at least one-third of hospitalisations amongst cardiac patients, with escalating mortality and healthcare costs on both public and private health care. Both prevalence and incidence of heart failure increase steeply with advancing age, making it a growing public health problem. …”
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Impact behavior of gravity cast AlSi10Mg alloy: Effect of hot isostatic pressing and innovative high pressure T6 heat treatment by Luca Girelli, Maverick Giovagnoli, Marialaura Tocci, Annalisa Fortini, Marcello Gelfi, Mattia Merlin, Annalisa Pola

“…At the same time, the innovative high-pressure T6 is able to ensure similar results than those of hot isostatic pressing followed by T6, leading to a significant decrease in the treatment duration and costs and reducing the carbon footprint of the manufacturing process.…”
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An Optimization Method for the Remanufacturing Dynamic Facility Layout Problem with Uncertainties by Lingling Li, Congbo Li, Huijie Ma, Ying Tang

“…Facility layout design, as the cornerstone of effective facility planning, is concerned about resource localization for a well-coordinated workflow that leads to lower material handling costs and reduced lead times. However, due to stochastic returns of used products/components and their uncontrollable quality conditions, the remanufacturing process exhibits a high level of uncertainty challenging the facility layout design for remanufacturing. …”
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Evolution of the PRNT: Merging tradition and innovation to set the gold standard in the era of automation by Caio Denani, Ingrid Horbach, Bruno Setatino, Adriana Azevedo, Sheila Lima, Waleska Schwarcz, Ivanildo Sousa

“…However, automation adoption is often constrained by high costs and the need for regulatory frameworks to ensure data integrity. …”
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Hardfacing of metals: A review of consumables, properties and strengthening processes by Yimiao Ning, Zhijun Qiu, Bintao Wu, Zengxi Pan, Huijun Li

“…This technology significantly extends the lifespan of components subjected to abrasive, corrosive, or high-impact environments, thereby reducing maintenance costs and improving operational efficiency. This article provides a comprehensive review of various hardfacing technologies, detailing the feedstock materials utilised in diverse applications. …”
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Challenges and Strategies for Increasing the Popularity of Integrated Islamic Elementary Schools in Jambi Province by Fadlilah Fadlilah, Muhaiminah Jalal, Kiki Fatmawati, Wardatul Janah

“…The findings show the main challenges include competition with public schools, curriculum balance, education costs and parents' expectations. Strategies implemented include developing an integrated curriculum, improving the quality of teachers, developing facilities and actively involving parents. …”
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Optimal intervention design for tonsillitis transmission via compartmental modeling with stability analysis and control strategies by Mehmet Gümüş, Shewafera Wondimagegnhu Teklu, Aleyna Sezgin

“…Abstract Tonsillitis represents a significant public health concern, particularly for children and adolescents, leading to substantial socioeconomic costs. To address this, we developed a compartmental mathematical model to investigate the disease’s transmission dynamics and determine optimal intervention strategies. …”
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The Impact of Work Connectivity Behavior on Employee Time Theft: The Role of Revenge Motive and Leader–Member Exchange by Cuiying Wang, Jianfeng Huang, Jianping Zhu

“…However, employee time theft is widespread and costly across various industries, and related research remains relatively limited. …”
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Methods of analysis of linear integer decoding pseudo-random codes by Tamila Valerievna Lavrovska, Sergey Gennadiyevich Rassomakhin, Aleksandr Olegovich Malofey

“…Advantages of use of pseudorandom codes which will allow to lower channel costs of transmission, but will allow to increase speed significantly are given. …”
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Dynamic modeling in the functioning of security systems in the field of information security by A. M. Konakov, A. G. Pevneva

“…The application of the basics of dynamic modeling of data, processes and structures in terms of time, allows you to assess risks and threats, identify certain significant shortcomings and eliminate them, thereby optimizing costs, increasing the efficiency of ensuring security…”
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Bush Snapbean Production in Miami-Dade County, Florida by Shouan Zhang, Dakshina Seal, Monica Ozores-Hampton, Mary Lamberts, Yuncong Li, Waldemar Klassen, Teresa Olczyk

“… Miami-Dade County is the primary production region for fresh-market bush snapbeans with 57% or 18,696 acres of the Florida bean acreage. Production costs vary from $16.53 to $21.87 per 30 lb. bushel or $4,046 to $4,711 per acre. …”
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Item response theory analysis of daytime sleepiness as a symptom of obstructive sleep apnea by Gustaf J. Wellhagen, Mats O. Karlsson, Maria C. Kjellsson, Dirk Garmann, Astrid Bröker, Yang Zhang, Mika Nokela, Gerrit Weimann, Ashraf Yassen

“…However, it is time‐consuming, costly, and disregards aspects such as quality of life. …”
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Orthostatic hypertension in cardiovascular risk stratification in hypertensive patients by E. Yu. Gubareva, O. V. Fatenkov, I. V. Gubareva, D. A. Klimenko, L. Yu. Shvan, L. V. Limareva

“…Hypertension (HTN) is an important modifiable risk factor for cardiovascular disease associated with poor outcomes and high health care costs. The assessment of cardiovascular risk (CVR) according to the current ESC/ESH guidelines for the treatment of hypertensive patients presents a number of difficulties and initiates the search for new diagnostic methods that contribute to understanding the patient's phenotype, personalizing diagnostic and treatment tactics, and improving the outcomes of hypertensive patients. …”
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A Novel SPAST/SPG4 Splice-Site Variant in a Family with Dominant Hereditary Spastic Paraplegia by Nathaniel M. Robbins, Jillian R. Ozmore, Thomas L. Winder, Pedro Gonzalez-Alegre, Tanya M. Bardakjian

“…Diagnostic work-up to determine the etiology can be costly and invasive. Here we report the case of a man with slowly progressive spastic paraparesis. …”
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Improving Regional Allocation in the Clinical Laboratory Technologist Exam in South Korea by Dae Woong KIM, Je Keun JEON

“…Candidates from non-metropolitan areas face significant financial burdens because of high transportation and lodging costs, as they must travel long distances to access test centers. …”
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Sources of financing for social enterprises on the example of social cooperatives by Joanna Żurakowska-Sawa, Klaudia Artyszuk

“…Social cooperatives, as part of state aid, may obtain aid for setting up a cooperative or joining it after its establishment and for creating a job or financing wage costs. Conclusions In recent years, social cooperatives in Poland can develop largely thanks to support from public funds, mainly European.…”
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The concept of sustainable regional development – institutional aspects, policies and prospects by Radislav Jovovic, Mimo Draskovic, Milica Delibasic, Miroslav Jovovic

“…Virtual enterprise is a temporary alliance of enterprises that come together to share their skills, core competencies, costs and resources in order to better respond to rapidly changing market environment and dynamic customer demands. …”
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Striving for zero traditional and non-traditional healthcare-associated infections (HAI): a target, vision, or philosophy by Jaffar A. Al-Tawfiq

“…According to studies, patients with HAIs have longer hospital stays, higher mortality rates (ranging from 7% to 64.6%), and higher healthcare costs as a result of their extended care needs. This review will delve into the prevalence, consequences, and management strategies for both traditional and non-traditional HAIs.…”
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Electrical resistivity and induced polarization in the investigation of acid drainage in decommissioning a mine by Beatriz Guzzo Duz, César Augusto Moreira, Marcos Eduardo Hartwig, Felipe Queiroz Miano, Lucas Moreira Furlan

“…Abstract The opening and development of mines without previous planning can generate costly environmental liabilities that are difficult to recover. …”
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Research Progress on Chitinase and Chitosanase with Transglycosylation Activity by Yingying WEI, Minjuan GUI, Huihui SUN, Ling ZHAO, Rong CAO

“…The TG reaction offers advantages in producing oligosaccharides with high-degree polymerization, including easy accessibility to substrates and low production costs. This paper reviews recent advances in chitinases and chitosanases with TG activity, analyzes the key amino acid residues affecting TG activity in chitinases, and discusses the impact of molecular modifications of these key residues on TG activity. …”
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