From feed to food – Understanding the impact of aflatoxins consumption by Pakistani livestock by Abeera Umar, Syeda Qanita, Naeem Zada, Sabyan Faris Honey

“…Contaminated feed and animal products also have economic implications, like reduced marketability of animal products, trade restrictions on animal products and increased health care cost. By adopting a trans-disciplinary approach, interventions can target the root causes of aflatoxin contamination in livestock feed, promote sustainable agricultural practices and ensure safer food systems for animal and human beings, preserving the environmental integrity.…”
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Coniontins, lipopetaibiotics active against Candida auris identified from a microbial natural product fractionation library by Xuefei Chen, Kalinka Koteva, Sommer Chou, Allison Guitor, Daniel Pallant, Yunjin Lee, David Sychantha, Shawn French, Dirk Hackenberger, Nicole Robbins, Michael A. Cook, Eric D. Brown, Lesley T. MacNeil, Leah E. Cowen, Gerard D. Wright

“…Abstract The rise of drug-resistant fungal pathogens, including Candida auris, highlights the urgent need for innovative antifungal therapies. We have developed a cost-effective platform combining microbial extract prefractionation with rapid mass spectrometry-bioinformatics-based dereplication to efficiently prioritize previously uncharacterized antifungal scaffolds. …”
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The “Colors” of Moringa: Biotechnological Approaches by Edgar Yebran Villegas-Vazquez, Juan Ramón Padilla-Mendoza, Mayra Susana Carrillo-Pérez, Rocío Gómez-Cansino, Liliana Altamirano-Garcia, Rocío Cruz Muñoz, Alvaro Diaz-Badillo, Israel López-Reyes, Laura Itzel Quintas-Granados

“…AI and deep learning enhance Moringa breeding, allowing for faster, cost-effective development of improved varieties. …”
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Strengthening workforce resilience to sustain community health services during crises: evidence from Chinese general practitioners by Botang Guo, Botang Guo, Yongbin Li, Ying Fu, Minyao Li, Yue Wang, Shuyu Liu, Yanjuan Zhou, Yu Liu, Ping Tang

“…Strengthening organizational resilience and fostering work engagement may offer cost-effective, non-technological strategies to maintain essential health service delivery capacity during future pandemics, aligning with broader goals of economic stability and pandemic preparedness.…”
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Challenges and Mitigation Strategies in the Development and Feasibility Assessment of a Digital Mental Health Intervention for Depression (VMood): Mixed Methods Feasibility Study by Leena W Chau, Jill K Murphy, Vu Cong Nguyen, Hai Nhu Tran, Harry Minas, Raymond W Lam, Kanna Hayashi, Thi Thanh Xuan Nguyen, Emanuel Krebs, John O'Neil

“…The research team is currently testing the effectiveness and cost-effectiveness of VMood in a randomized controlled trial across 8 provinces in Vietnam informed by the results of this feasibility assessment. …”
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A real-world study on the efficacy and safety of low-dose PD-1 monoclonal antibody alone or in combination as the first-line treatment for advanced non-small cell lung cancer by Tao Han, Xin Li, Lu Xu, Jingqi Sun, Junli Hao, Sha Shi, Heming Li, Mingfang Zhao

“…These findings suggest a cost-effective and safe alternative, warranting validation in future randomized controlled trials.…”
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Impact of the announcement and implementation of the UK Soft Drinks Industry Levy on sugar content, price, product size and number of available soft drinks in the UK, 2015-19: A co... by Peter Scarborough, Vyas Adhikari, Richard A Harrington, Ahmed Elhussein, Adam Briggs, Mike Rayner, Jean Adams, Steven Cummins, Tarra Penney, Martin White

“…<h4>Conclusions</h4>The results suggest that the SDIL incentivised many manufacturers to reduce sugar in soft drinks. Some of the cost of the levy to manufacturers and importers was passed on to consumers as higher prices but not always on targeted drinks. …”
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Real-world effectiveness of novel hormonal agents and docetaxel in patients with prostate cancer: A head-to-head comparison by Yuanshi Jiao, Isaac Ho, Tunghiu Li, Rong Na, Chunka Wong, Jiaqi Wang, Steven Wai Kwan Siu, Yan Wei, Yingyao Chen, Esther W. Chan, Xue Li

“…These findings indicate comparable effectiveness between NHAs and chemotherapy, with a more favorable HRU profile for NHA-treated patients, suggesting potential cost-effectiveness of NHAs.…”
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Therapeutic Effects of Forest Bathing on Human Health: A Systematic Review by Adrianna Samoraj, Jakub Zajączkowski, Paulina Krzeszowska, Kacper Stępniak, Karolina Marrodán-Wojtczak, Jan Wilk, Jakub Jarmołowicz, Aleksandra Kujawa, Karolina Krochmal, Radosław Kuźma

“…Conclusions: Forest bathing represents an accessible and cost-effective intervention that holds significant potential for enhancing human quality of life. …”
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Can high-lipid concentrates offset the high enteric methane production caused by high-forage diets fed to lactating dairy cows? by N. Ayanfe, I. Tapio, S. Ahvenjärvi, M. Rinne, A. Sairanen, A.R. Bayat

“…These findings suggest that supplementing HF diets with HEE concentrates could be a practical and cost-effective strategy for sustainable dairy production.…”
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Healthcare access and utilisation trends among the elderly in India: Evidence from the LASI Wave-1 survey by Dhruvendra Lal, Amrit Virk, Ashish Goel, Sonu Goel, Kavisha Kapoor Lal, Suneela Garg, Bhavneet Bharti

“…Expanding affordable health insurance can reduce out-of-pocket costs and improve health outcomes in India's ageing population, addressing key Sustainable Development Goals (SDGs), particularly SDG 1,3,10 and 11.…”
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Hand hygiene practices during the COVID-19 pandemic and associated factors among barbers and beauty salon workers in Ethiopia. by Tarikuwa Natnael, Metadel Adane, Solomon Goraw

“…Moreover, government and non-government organizations should work together to provide alcohol-based hand sanitizer at a low cost to those barbershops and beauty salons if there is no access to water and soap.…”
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Evaluation of an integrated care program for thoracic surgery in Ontario, Canada: a historical cohort study by Nicholas Bakewell, Catherine Liang, Tsoleen Ayanian, Sanjana Sundaram, Kazuhiro Yasufuku, Meghan O’Neill, Kathy Kornas, Lori Diemert, Megan Samantha Lowe, Melissa Chang, Laura C. Rosella

“…Conclusions IC programs may reduce post-discharge ED visits, LOS and healthcare costs for thoracic surgery patients, particularly for those in a low care path. …”
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Construction and screening of L-valine high-yielding Escherichia coli using an artificial screening marker by Bowen Du, Bowen Du, Sheng Gao, Sheng Gao, Daixue Kou, Daixue Kou, Yinuo Li, Yinuo Li, Dan Li, Dan Li, Yongsheng Cao, Yongsheng Cao, Cuiping Yang, Chuanzhuang Guo, Jianbin Wang, Junqing Wang, Junqing Wang, Nan Li, Nan Li

“…The selection and breeding of high-yielding, low-cost, and genetically stable production strains have become a key objective in the L-valine production industry.MethodsUsing Escherichia coli DB-1-1, we developed a screening marker LESG associated with intracellular L-valine levels by choosing GTC, a less common codon for L-valine, in place of all L-valine codons. …”
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Calculation of mass discharge of the Greenland ice sheet in the Earth System Model by O. O. Rybak, E. M. Volodin, A. P. Nevecherya, P. A. Morozova, M. M. Кaminskaya

“…To provide long runs of a fully coupled ESM at a lower computational cost, we utilized an asynchronous coupling when a 100-yr run of the GrISM corresponds to 1-yr run of the INMCM. …”
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Refining population density estimation from track counts: improving daily travel distance estimates through trailing of large herbivores in the Kalahari, Botswana by Marie-Charlotte Gielen, Alessandro Araldi, Marie Jardeaux, Seitshiro Pule, Senxwai Mosololo, Xee Fire Seganaphohu, Duela Seganaphofu, Tebelelo Gabaikanye, Pogiso Ithuteng, Derek Keeping, Nicolas Schtickzelle

“…This study aims to improve the accuracy of FMP-derived density estimates by refining both empirical and allometric $$\widehat{\text{M}}$$ M ^ estimations. Methods We tested a cost-effective forward trailing technique to collect high-quality empirical $$\widehat{\text{M}}$$ M ^ for large herbivore species with local certified trackers, in Khutse Game Reserve and Central Kalahari Game Reserve, Botswana. …”
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Experimental and numerical study on radiative cooling of a linear alternator in a free-piston Stirling electric generator by Qingyue Jin, Guoyao Yu, Haojie Sun, Jing Luo, Hangyu Ma, Yong Li, Shunmin Zhu, Ercang Luo

“…This paper proposes an innovative approach for the first time that utilizes a high emissivity coating formulated from a blend of microsilica and graphene nanosheets to enhance the radiation heat dissipation inside the LAs, offering advantages of structural simplicity and cost-effectiveness. To elucidate the radiative heat transfer characteristics interacted with the oscillating flow within the LA, firstly, a CFD model was developed to analyse the oscillating flow coupled radiative heat transfer within a 1.5-kW LA. …”
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A high-efficiency and stable transfection approach by using calcium phosphate in HEK293T cells by Kuang Ye, Fang Yourong, Liu Li, Wang Rong, Yan Ziqin, Li Hailong, Meng Fanguo, Sheng Qing, Ou Wenbin

“…Calcium phosphate transfection is one of the major methods for DNA transfer to eukaryocyte cells and with lower toxicity and cost than lipofection. However, the application of calcium phosphate transfection method was limited due to its low transfection efficiency and instability.To establish a highly efficient and stable transfection approach to overexpress exogenous protein abundantly in HEK293T cells in vitro, green fluorescent protein (GFP) plasmid DNA was transfected by using calcium phosphate with optimal DNA amount and vortex time of calcium phosphate-DNA complex in absence or presence of common transfection enhancers including glycerol, sodium butyrate, and chloroquine.The protocol of calcium phosphate transfection was as follows. …”
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A Substrate–Product Switch Mathematical Model for the Growth Kinetics of Ethanol Metabolism from Longan Solid Waste Using <i>Candida tropicalis</i> by Juan Feng, Chatchadaporn Mahakuntha, Su Lwin Htike, Charin Techapun, Yuthana Phimolsiripol, Pornchai Rachtanapun, Julaluk Khemacheewakul, Siraphat Taesuwan, Kritsadaporn Porninta, Sumeth Sommanee, Rojarej Nunta, Noppol Leksawasdi

“…The proposed model and kinetics provide valuable insights for designing and optimizing ethanol fermentation, contributing to more sustainable and cost-effective ethanol production.…”
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Process evaluation of a randomised trial of a triple low-dose combination pill strategy to improve hypertension control: a qualitative study by Vanessa Selak, Anushka Patel, Anthony Rodgers, Stephen Jan, Dorairaj Prabhakaran, Abdul Salam, Lakshmi K Josyula, Nitish Naik, Pavithra Godamunne, Arunasalam Pathmeswaran, Tracey Laba, Rupasvi Dhurjati, Asita de Silva, Pallab Kumar Maulik, Rama Guggilla, Ruth Webster (Griffiths)

“…The Triple Pill vs Usual Care Management for Patients with Mild-to-Moderate Hypertension (TRIUMPH) trial evaluated the effectiveness, cost-effectiveness and acceptability of early use of low-dose triple fixed-dose combination of BP-lowering drugs (‘triple pill’) compared with usual care in the management of hypertension. …”
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