Pharmacoeconomic analysis of the use of a fixed combination of tiotropium bromide and olodaterol as maintenance therapy in patients with chronic obstructive pulmonary disease in th... by S. К. Zyryanov, I. N. Dyakov

“…The use of a fixed combination of tiotropium bromide + olodaterol in such patients instead of monotherapy will reduce the direct costs of hospitalization by 21.1%, and the total costs (direct and indirect) – by 4.6%. …”
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Theoretical analysis of the forming process of closed die forging with flash and optimization design method of flash gutter by Xiang Zhang, Volodymyr Borysevych

“…The scientific novelty of the results obtained is as follows: A mathematical model of closed die forging with flash was established to analyze the metal plastic deformation and stress distribution, providing theoretical support for die design optimization, forging quality improvement, cost reduction, and productivity improvement. Using the Deform-2D finite element simulation, the optimal design criterion for the flash was refined, resulting in a substantial reduction in the flash amount and material savings.…”
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Applying Energy Dissipation Rate GNSS Accelerometry to a Non‐Circular Orbiting Satellite by D. J. Fitzpatrick, R. L. Bishop, M. D. Pilinski, S. E. Palo

“…Abstract The increase in the number of objects in Low‐Earth Orbit has heightened the demand for high‐accuracy orbital prediction models driven by dependable measurements of thermospheric mass density (TMD). Given the added cost and complexity burden of equipping satellites with high precision accelerometers, recent attention has focused on alternative techniques for observing TMD such as “GNSS accelerometry,” which involves harnessing spacecraft as instruments themselves to quantify thermospheric density vis‐à‐vis orbital decay. …”
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Implementation of a Neural Network for Adaptive PID Tuning in a High-Temperature Thermal System by Juan Carlos Almachi, Ramiro Vicente, Edwin Bone, Jessica Montenegro, Edgar Cando, Salvatore Reina

“…Relying on commodity hardware and open-source tools, this approach offers a cost-effective solution for legacy furnace upgrades and provides a replicable model for adaptive control in high-temperature, safety-critical environments like metal processing, battery cycling, and nuclear systems.…”
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Efficacy of silicone foam dressings in preventing pressure injuries in the sacral and heel areas of patients: a meta-analysis by Tingkui Fu, Xiuqin Wu, Biao Yu

“…However, further research is required to explore their cost-effectiveness and long-term outcomes to strengthen evidence for broader implementation.…”
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Dietary index for gut microbiota and its inverse association with female infertility: evidence from NHANES 2013–2018 by Chiqiang Cheng, Xi He, Chunhua Zhou, Liu Ouyang, Yang Zhao, Jiahui Li, Fangfang Liu, Xia Gao

“…Subgroup analyses indicated stronger associations in women with lower education levels and those with coronary heart disease (P for interaction <0.05).ConclusionOur findings demonstrate that a higher DI-GM score is associated with a reduced risk of female infertility, suggesting that dietary interventions targeting gut microbiota may offer a cost-effective strategy for improving reproductive health. …”
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Feasibility Study of Using 5G Signals for Illumination Purposes in Passive Radar by V. M. Kutuzov, V. I. Veremyev, Nguyen Van Tuan, E. N. Vorobev

“…The absence of its own transmitter determines the main advantages of passive radars compared to conventional active radars: lower cost, silent operation, no electromagnetic impact on other radio equipment and the environment. …”
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Cholecalciferol (vitamin D3): efficacy, safety, and implications in public health by Esteban Ortiz-Prado, Jorge Vasconez-Gonzalez, Juan S. Izquierdo-Condoy, Isaac A. Suárez-Sangucho, José Guillermo Prieto-Marín, Karen Bereniss Villarreal-Burbano, Mateo Alejandro Barriga-Collantes, John Alexander Altamirano-Castillo, Domenic Anahi Borja-Mendoza, Jean Carlo Pazmiño-Almeida, María Paz Cadena-Padilla

“…Food fortification and targeted screening remain underutilized yet cost-effective public health interventions. Overall, vitamin D₃ represents a promising but complex therapeutic agent, necessitating further rigorously designed clinical trials to establish evidence-based guidelines for its use in diverse pathological conditions.…”
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Estimation of water use efficiency (WUE) for efficient irrigation level of oil palm during the main nursery phase by Iput Pradiko, Rana Farrasati, Nuzul Hijri Darlan, Sumaryanto Sumaryanto, Dhaffa Agung Thirafi

“…Therefore, irrigation in oil palm nurseries should be based on ETa to improve efficiency and lower costs. These findings offer practical guidance for farmers or plantation management to support more sustainable and cost-effective irrigation practices.…”
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High intensity focused ultrasound periosteal ablation in an animal model: potential for palliation of bone metastases by Ron Aginsky, Suzanne Leblang, Eric Miller, Brian Skoglind, Abraham Nyska, Niv Rebhun, Michael Gofeld, Jean-Francois Aubry, Arik Hananel

“…Ablation of sensory nerves endings along the periosteum with magnetic resonance imaging guided high intensity focused ultrasound (MRgFUS) proved safe and clinically effective for pain relief in patients with bone metastases, received FDA and CE approval, but has not gained widespread adoption due to significant cost and procedural and logistical complexity. This preclinical study evaluated the safety and feasibility of a fluoroscopy-guided high intensity focused ultrasound platform to ablate a targeted region along the surface of bones.Methods Two healthy adult pigs received 6 kJ to 10 kJ sonications to the femur, ileum, and ribs. …”
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Amyloidosis Screening by Biopsy During Carpal Tunnel Release: A Systematic Review and Meta-analysis by Peter C. Ferrin, MD, Gwendolyn Daly, MD, Angelo B. Lipira, MD, MA, Ravi F. Sood, MD, MS

“…Future studies should further refine diagnostic criteria to optimize cost-effectiveness of widespread screening.…”
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Understanding smallholder dairy productivity and poverty reduction in Eritrea by Stephen Onakuse, Lilian Treasure, Okbasilassie Msghina, Kahsay Negash

“…Dairy experience, labor cost, and membership in a cooperative had a posi­tive effect on the labor productivity of male farm­ers. …”
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Green Protein Extraction from Hazelnut Press Cake: Yield, Efficiency, and Secondary Structure Analysis by Bruna Anzà, Silvia Fraterrigo Garofalo, Alessandro Lapolla, Debora Fino

“…Alkali solubilization/isoelectric precipitation (ALKIS) is a widely used method for protein extraction due to its simplicity and cost-effectiveness. Despite that, ALKIS extraction has limitations due to the alteration in protein functionality, a reduction in protein stability, and significant wastewater production. …”
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A Heuristic Optical Flow Scheduling Algorithm for Low-Delay Vehicular Visible Light Communication by Zhengying Cai, Shumeng Lei, Jingyi Li, Chen Yu, Junyu Liu, Guoqiang Gong

“…Finally, a series of benchmark experiments are conducted to show that the proposed algorithm can efficiently schedule optical flows with minimal delay. The cost of this algorithm is very low, and it is suitable for deployment on edge computing platforms such as vehicles.…”
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BDS-PPP-B2b-Based Smartphone Precise Positioning Model Enhanced by Mixed-Frequency Data and Hybrid Weight Function by Zhouzheng Gao, Zhixiong Wu, Shiyu Liu, Cheng Yang

“…Compared to high-cost hardware-based Global Navigation Satellite System (GNSS) positioning techniques, smartphone-based precise positioning technology plays an important role in applications such as the Internet of Things (IoT). …”
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The Relevance of Osteoscintigraphy Technique in Early Detection of Bone Metastatic Lesions: a Systematic Review by E. A. Litvinenko, I. V. Burova

“…It was shown that OSG will cost 6 times cheaper than positron emission tomography (PET), and 3 times cheaper than magnetic resonance imaging (MRI). …”
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How the Functional Constitution of Plant Communities in Field Margins Affects Wild Bee Community Composition and Functional Structure by Jane Morrison, Jordi Izquierdo, Eva Hernández Plaza, José L. González-Andújar

“…Maintaining flowering plants in agricultural field margins is often recommended as a cost-effective and efficient method of offering habitat for wild pollinator conservation. …”
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Portable cotton swab biosensor for rapid naked-eye detection of Helicobacter pylori by Ghadeer.A.R.Y. Suaifan, Asmaa Alnajajrah, Ward Abu Jbara, Amr A. El-Mousa, Fahid Abu Jbara, Doha A.I. Al-Omari, Mayadah B. Shehadeh

“…This study presents the development of a rapid, simple and cost-effective cotton swab-based colorimetric biosensor for the visual detection of H. pylori in saliva. …”
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“Smart support for fruit farm business decision-making: A framework for digital controlling adoption” by Luis Müller, Robert Luer, Wolfgang Lentz

“…This study contributes a conceptual framework to broaden the understanding of the often negatively perceived cost-benefit ratio of controlling in small and medium-sized enterprises and identifies strategies to strengthen its practical relevance.…”
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LSD-Det: A Lightweight Detector for Small Ship Targets in SAR Images by Zhen Wang, Bin Qin, Shang Gao

“…Experiments conducted on two publicly available SAR ship detection datasets, SSDD and HRSID, demonstrate that LSD-Det significantly reduces computational cost while maintaining high detection performance. …”
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