Soil variation response is mediated by growth trajectories rather than functional traits in a widespread pioneer Neotropical tree by Levionnois, Sébastien, Tysklind, Niklas, Nicolini, Eric, Ferry, Bruno, Troispoux, Valérie, Le Moguedec, Gilles, Morel, Hélène, Stahl, Clément, Coste, Sabrina, Caron, Henri, Heuret, Patrick

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Identification of Plasmodium falciparum and host factors associated with cerebral malaria: description of the protocol for a prospective, case-control study in Benin (NeuroCM) by Valentin Joste, Laurine Maurice, Gwladys I Bertin, Agnès Aubouy, Farid Boumédiène, Sandrine Houzé, Daniel Ajzenberg, Nicolas Argy, Achille Massougbodji, Ida Dossou-Dagba, Maroufou Jules Alao, Michel Cot, Philippe Deloron, Jean-François Faucher, Dissou Affolabi, Hélène Authier, Linda Ayedadjou, Bibiane Biokou, Agnès Coste, Jean-Eudes Degbelo, Latifou Dramane, Sayeh Jafari-Guemouri, Claire Kamaliddin, Elisée Kinkpe, Anaïs Labrunie, Yélé Ladipo, Thomas Lathiere, Audrey Mowendabeka, Jade Papin, Bernard Pipy, Pierre-marie Preux, Marie Raymondeau, Jade Royo, Darius Sossou, Brigitte Techer, Bertin Vianou

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Efficacy of corticosteroids addition to multimodal cocktail periarticular injection in total knee arthroplasty with hemophilic arthropathy by Hai Su, Shenxu Yu, Lei Chen, Haojing Zhou, Yichen Gong, Hua Huang, Shuaijie Lv, Peijian Tong, Xun Liu, Jun Ying

“…A three-month follow-up study was conducted to compare the postoperative outcomes in the above groups, including Visual Analogue Scale (VAS) scores, knee range of motion (ROM), Knee Society Score (KSS), inflammatory markers (C-reactive protein, CRP, and Interleukin- 6, IL- 6), and hospitalization parameters (body temperature, length of hospital stay, hospitalization costs, and perioperative usage of coagulation factor VIII). …”
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Genetic Polymorphisms on TNFA, TNFRSF1A, and TNFRSF1B Genes Predict the Effectiveness of Anti-TNF-α Treatment in Inflammatory Bowel Disease Patients by Michelangelo Rottura, Igor Pirrotta, Domenico Antonio Giorgi, Natasha Irrera, Vincenzo Arcoraci, Federica Mannino, Rosario Campisi, Chiara Bivacqua, Laura Patanè, Giuseppe Costantino, Socrate Pallio, Walter Fries, Anna Viola, Giovanni Pallio

“…<b>Conclusions:</b> These results suggest that the evaluation of SNPs in <i>TNF-α</i>, <i>TNFR1A</i>, and <i>TNFR1B</i> genes could improve the management of IBD, leading to more effective, individualized treatment plans and a reduction in healthcare costs associated with ineffective therapies and disease complications.…”
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Genetic Parameter Estimation of Body Weight and <i>Vp</i>_AHPND Resistance in Two Strains of <i>Penaeus vannamei</i> by Guixian Huang, Jie Kong, Jiteng Tian, Sheng Luan, Mianyu Liu, Kun Luo, Jian Tan, Jiawang Cao, Ping Dai, Guangfeng Qiang, Qun Xing, Juan Sui, Xianhong Meng

“…These findings also suggest that infection frequency and observation time influence resistance performance and breeding selection, emphasizing the need for a tailored resistance evaluation program to improve breeding efficiency and reduce costs.…”
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Repurposing FDA-Approved Agents to Develop a Prototype <i>Helicobacter pylori</i> Shikimate Kinase (HPSK) Inhibitor: A Computational Approach Using Virtual Screening, MM-GBSA Calcu... by Abdulaziz H. Al Khzem, Tagyedeen H. Shoaib, Rua M. Mukhtar, Mansour S. Alturki, Mohamed S. Gomaa, Dania Hussein, Nada Tawfeeq, Mohsina Bano, Mohammad Sarafroz, Raghad Alzahrani, Hanin Alghamdi, Thankhoe A. Rants’o

“…While current therapies face challenges from rising antibiotic resistance, particularly to clarithromycin, alongside treatment complexity and costs, the World Health Organization has prioritized the development of new antibiotics to combat this high-risk pathogen. …”
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Highly multiplexed molecular inversion probe panel in Plasmodium falciparum targeting common SNPs approximates whole-genome sequencing assessments for selection and relatedness by Karamoko Niaré, Karamoko Niaré, Rebecca Crudale, Abebe A. Fola, Abebe A. Fola, Neeva Wernsman Young, Victor Asua, Victor Asua, Melissa D. Conrad, Pierre Gashema, Anita Ghansah, Stan Hangi, Deus S. Ishengoma, Deus S. Ishengoma, Jean-Baptiste Mazarati, Ayalew Jejaw Zeleke, Philip J. Rosenthal, Abdoulaye A. Djimdé, Abdoulaye A. Djimdé, Jonathan J. Juliano, Jonathan J. Juliano, Jonathan J. Juliano, Jeffrey A. Bailey, Jeffrey A. Bailey

“…While whole-genome sequencing (WGS) is optimal in terms of assessing the entire genome, it is costly for numerous samples. Targeted approaches selectively enriching for the sequence of interest are more affordable and have higher throughput but sometimes lack adequate information content for key analyses.MethodsWe have developed a highly multiplexed molecular inversion probe (MIP) panel (IBC2FULL) targeting 4,264 single-nucleotide polymorphisms (SNPs) with ≥5% minor allele frequency (MAF) in Sub-Saharan African regions from publicly available Plasmodium falciparum WGS (n = 3,693). …”
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Effects of partial silage replacement with corn stover pellets on the rumen microbiota and serum metabolome of breeding cows by Chenyue Jiao, Changze Cui, Youpeng Qi, Meixian Zhang, Pengcheng Zhao, Shaopeng Chen, Xiangyan Wang, Jiang Hu, Jiang Hu, Bingang Shi, Bingang Shi, Ting Liu, Ting Liu, Zhidong Zhao, Zhidong Zhao, Fangfang Zhao, Fangfang Zhao

“…IntroductionStraw pellet ration replacing part of silage is of great significance for farmers to save farming costs and solve the lack of feed resources. A comprehensive analysis of rumen microbial and serum metabolite compositions is conducted to promote the development of the modern breeding cows-feeding industry.MethodsIn this study, 18 healthy 2-year-old Simmental breeding cows weighing 550 ± 20 kg were selected and randomly divided into two groups. …”
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Identifying the predictors of ultra early neurological improvement and its role in functional outcome after endovascular thrombectomy in acute ischemic stroke by Yuzheng Lai, Mohammad Mofatteh, José Fidel Baizabal-Carvallo, José Fidel Baizabal-Carvallo, Jianfeng He, Wenhao Wu, Daohong Wang, Wenshan Yan, Jicai Ma, Sijie Zhou, Yu Sun, Yu Sun, Yi He, Shumei Li, Hao Sun

“…In addition, lower hospitalization costs were associated with patients who had UENI, compared to No-UENI (p = 0.003). …”
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The role of smell in medical and psychological disorders: An interdisciplinary approach by Giuseppe Riva

“…Further studies are however needed for an early treatment in order to increase the patients’ quality of life [9] and to reduce the direct and indirect costs for the healthcare systems. Furthermore, the psychophysical evaluation of olfactory impairments associated with some treatments, such as radiotherapy and chemotherapy, and with several types of rhinitis could help address patients’ complaints, and increase the patient’s quality of life [10, 11]. …”

Agricultural Policies and Practices: Pathways for Transformation by Hari Sharma Neupane, Bikram Acharya, Pradeep Wagle, Buddhi Raj Gyawali

“…Similarly, the Technology and Infrastructure Development theme focused on varied avenues of innovative technology (such as UAV, GIS, and Remote Sensing), farm mechanization, and smart and efficient irrigation practices to optimize costs of production, labor, fertilizer shortages, and monitoring of plant and soil health Finally, the Governance theme underpinned coherence and discordance between the policy frameworks and governing structures/mechanisms of three levels of government and opportunities for realignment for agricultural transformation as well as a local governance framework for agricultural service delivery at a municipality level. …”
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CP Violation: Differing Binding Energy Levels of Quarks and Antiquarks, and Their Transitions in Λ-Baryons and B-Mesons by Dimitris M. Christodoulou, Demosthenes Kazanas

“…The wider quark range stems from the flip <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi mathvariant="normal">s</mi><mo>→</mo><mi mathvariant="normal">b</mi></mrow></semantics></math></inline-formula>, which costs 283 MeV more (or <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mn>3</mn><mo>×</mo></mrow></semantics></math></inline-formula> more) than the corresponding antiquark flip <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mover><mi mathvariant="normal">s</mi><mo>¯</mo></mover><mo>→</mo><mover><mi mathvariant="normal">b</mi><mo>¯</mo></mover></mrow></semantics></math></inline-formula>. …”
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ID251 Jornada Assistencial de Valor do RARAS (JAV RARAS): Estudo de vida real no Sistema Único de Saúde (SUS) by Luana Lopes, Guillermo Montero, Alef Almeida, Myrianne Barbosa, Ney Boa Sorte, Ida Schwartz, Camila Azevedo, Gabriel Ogata, Temis Felix, Marcelo Nita

“…Os dados de custos, ao longo de um ciclo de cuidado, foram obtidos através do “Time-Driven Activity-Based Costing” (TDABC). Realizamos uma análise comparativa dos custos associados aos Protocolos Clínicos e Diretrizes Terapêuticas (PCDTs) e os mensurados com o TDABC. …”
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Allelic, Genotypic, and Haplotypic Analysis of Cytokine IL17A, IL17F, and Toll-like Receptor TLR4 Gene Polymorphisms in Metabolic-Dysfunction-Associated Steatotic Liver Disease: In... by Sorina-Cezara Coste, Olga Hilda Orășan, Angela Cozma, Vasile Negrean, Teodora Gabriela Alexescu, Mirela Georgiana Perne, George Ciulei, Adriana Corina Hangan, Roxana Liana Lucaciu, Mihaela Iancu, Lucia-Maria Procopciuc

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Social Progress and Economic Growth based on Simultaneous Equations of Panel Data by Seyed Ehsan Hosseinidoust, Akbar Khodabakhshi, Saeedeh Ahmadi

“…The contribution of social progress into the performance of the economy and development process can be considered through reducing inequality and poverty, increasing market efficiency, economic growth, reducing costs, increasing the efficiency of human resources and capital, creating economic institutions and organizations and improving their performance, and increasing investment and employment, as well as increasing innovation and technology. …”
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Intrinsic capacity in patients with dementia with Lewy bodies compared with those with Alzheimer’s disease: A cross-sectional study by Marie Collin, Justine Bonnet-Chateau, Victor Gilles, Sophie Dautricourt, Thomas Gilbert, Zaza Makaroff, Marie-Hélène Coste, Virginie Dauphinot, Antoine Garnier-Crussard

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Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer. by Christopher A Maxwell, Javier Benítez, Laia Gómez-Baldó, Ana Osorio, Núria Bonifaci, Ricardo Fernández-Ramires, Sylvain V Costes, Elisabet Guinó, Helen Chen, Gareth J R Evans, Pooja Mohan, Isabel Català, Anna Petit, Helena Aguilar, Alberto Villanueva, Alvaro Aytes, Jordi Serra-Musach, Gad Rennert, Flavio Lejbkowicz, Paolo Peterlongo, Siranoush Manoukian, Bernard Peissel, Carla B Ripamonti, Bernardo Bonanni, Alessandra Viel, Anna Allavena, Loris Bernard, Paolo Radice, Eitan Friedman, Bella Kaufman, Yael Laitman, Maya Dubrovsky, Roni Milgrom, Anna Jakubowska, Cezary Cybulski, Bohdan Gorski, Katarzyna Jaworska, Katarzyna Durda, Grzegorz Sukiennicki, Jan Lubiński, Yin Yao Shugart, Susan M Domchek, Richard Letrero, Barbara L Weber, Frans B L Hogervorst, Matti A Rookus, J Margriet Collee, Peter Devilee, Marjolijn J Ligtenberg, Rob B van der Luijt, Cora M Aalfs, Quinten Waisfisz, Juul Wijnen, Cornelis E P van Roozendaal, HEBON, EMBRACE, Douglas F Easton, Susan Peock, Margaret Cook, Clare Oliver, Debra Frost, Patricia Harrington, D Gareth Evans, Fiona Lalloo, Rosalind Eeles, Louise Izatt, Carol Chu, Diana Eccles, Fiona Douglas, Carole Brewer, Heli Nevanlinna, Tuomas Heikkinen, Fergus J Couch, Noralane M Lindor, Xianshu Wang, Andrew K Godwin, Maria A Caligo, Grazia Lombardi, Niklas Loman, Per Karlsson, Hans Ehrencrona, Anna von Wachenfeldt, SWE-BRCA, Rosa Bjork Barkardottir, Ute Hamann, Muhammad U Rashid, Adriana Lasa, Trinidad Caldés, Raquel Andrés, Michael Schmitt, Volker Assmann, Kristen Stevens, Kenneth Offit, João Curado, Hagen Tilgner, Roderic Guigó, Gemma Aiza, Joan Brunet, Joan Castellsagué, Griselda Martrat, Ander Urruticoechea, Ignacio Blanco, Laima Tihomirova, David E Goldgar, Saundra Buys, Esther M John, Alexander Miron, Melissa Southey, Mary B Daly, BCFR, Rita K Schmutzler, Barbara Wappenschmidt, Alfons Meindl, Norbert Arnold, Helmut Deissler, Raymonda Varon-Mateeva, Christian Sutter, Dieter Niederacher, Evgeny Imyamitov, Olga M Sinilnikova, Dominique Stoppa-Lyonne, Sylvie Mazoyer, Carole Verny-Pierre, Laurent Castera, Antoine de Pauw, Yves-Jean Bignon, Nancy Uhrhammer, Jean-Philippe Peyrat, Philippe Vennin, Sandra Fert Ferrer, Marie-Agnès Collonge-Rame, Isabelle Mortemousque, GEMO Study Collaborators, Amanda B Spurdle, Jonathan Beesley, Xiaoqing Chen, Sue Healey, kConFab, Mary Helen Barcellos-Hoff, Marc Vidal, Stephen B Gruber, Conxi Lázaro, Gabriel Capellá, Lesley McGuffog, Katherine L Nathanson, Antonis C Antoniou, Georgia Chenevix-Trench, Markus C Fleisch, Víctor Moreno, Miguel Angel Pujana

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Characterization of jamun (Syzygium cumini Skeels) accessions for economic traits based on multivariate analysis by Prakash Chandra Tripathi, Anuradha Sane, Karunakaran Ganesan, Sankar Vadivel, Prakash Kumar, Kanupriya Chaturvedi, Ruchitha Thimmarayappa

“…The identification of high-pulp, seedless genotypes is particularly significant for commercial applications, as these traits can increase yield per fruit and reduce processing costs for value-added products. The variability observed among the genotypes can support targeted breeding efforts for enhanced fruit quality, resilience, and adaptability, ultimately benefiting both growers and consumers. …”
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PE-068 JAV (jornada assistencial de valor) RARAS: análise da aderência aos Protocolos Clínicos e Diretrizes Terapêuticas (PCDT) no Angioedema associado a deficiência de C1 e Mucopo... by Camila Azevedo, Marcelo Nita, Luana Lopes, Myrianne Barbosa, Thiago Godoy, Altacilio Nunes, Temis Felix

“…Material e Métodos: A avaliação será realizada utilizando dados da jornada do paciente obtidos através do estudo do Time-Driven Activity-Based Costing (TDABC). O estudo de adesão ao PCDT baseia-se nos processos assistenciais mapeados com TDABC. …”
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Semi-quantitative analysis of 18F fluorodeoxyglucose uptake in the assessment of disease activity and therapeutic response in rheumatoid arthritis: An institutional experience by Reddy Ravikanth, Jyotin Singh

“…It is considered that 18F-FDG PET scan is generally very expensive; however, the information from 18F-FDG PET about patients during biological treatments helps discontinuation of these treatments with incomplete response despite its high costs and with possible side effects such as malignant lymphoma. …”
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