Multi-objective optimization of soil water-nitrogen management practice and seeding rate for sustainable soybean production on the Loess Plateau of China by Zhenqi Liao, Xiaohui Ding, Hongxin Zhang, Hui Zhang, Zhijun Li, Fucang Zhang, Junliang Fan

“…Compared with the local management strategy (NMN60D16), RWN30D32 significantly (p < 0.05) increased the canopy photosynthetic capacity, biological yield, grain yield, seed protein yield, seed oil yield, net income, ratio of output over input costs, crop water productivity, partial factor productivity of nitrogen and radiation use efficiency by 22.8 %, 66.7 %, 35.9 %, 20.1 %, 23.9 %, 69.8 %, 28.4 %, 29.0 %, 171.8 % and 18.5 %, while it decreased the hundred-grain weight, number of pods, seed protein content, seed oil content, energy use efficiency and carbon productivity by 5.4 %, 34.2 %, 11.6 %, 8.8 %, 20.5 % and 69.0 %, respectively. …”
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Decentralized biobanking platform for organoid research networks by Marielle Gross, Marielle Gross, Ananya Dewan, Mario Macis, Mario Macis, Eve Budd, M. Eifler, Olayinka Odeniran, Jeff Kahn, Jeff Kahn, Jeff Kahn, Robert Clell Miller, Robert Clell Miller, William Sanchez

“…Implementing de-bi with ERC-1155 showed potential to minimize gas costs of on-chain activity vs ERC-721, though complementary layer-2 solutions will be essential for economic viability.ConclusionDecentralized biobanking has the potential to enhance efficiency, increase translational impact and drive research discovery through implementation of NFT digital twins for organoid research networks. …”
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Overcoming practical challenges to pilot Sierra Leone’s first school-based distribution of piperonyl butoxide-synergist ITNs: findings from a 2023 assessment in Kono district by Keith Esch, Fredrick Yamba, Kevin Opondo, Musa Sillah-Kanu, David Schnabel, Prince Owusu, Raymond Sudoi, Malia Skjefte, Wani Lahai, Mohamed G. Sheku, Mariama Kabba Jibatteh, Augustine Ngegbe, Jenny Carlson, Temitayo Labor, Djenam Jacob, Charlene Youseff, Elisabeth Tyler, Prince Nallo, Dennis Marke, Stephen Poyer

“…Gaps should be addressed for SBD scale-up. Research on costing, sustained levels of ITN use and access, and the effect of SBD ITNs on malaria parasitaemia may be considered by the NMCP.…”
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A patient self-report disability identifier within health service electronic medical records: evaluation of patient, carer and clinician acceptability by Joanne Rowe, Alexandra Devine, Nicole Merrick, Marie Huska, Kristen Morris, Kath Feely, Ahuva Segal, Louise Mogg, Jenni Medland, Rebecca Jamwal, Alison Smith, Maricar Gleich, Jeremiah Munakabayo, Christine Imms

“…Data analysis explored perspectives and experiences across eight constructs: general acceptability, affective attitude, burden, ethicality, intervention coherence, opportunity costs, self-efficacy, and perceived effectiveness. …”
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Diagnostic utility of single-locus DNA methylation mark in Sotos syndrome developed by nanopore sequencing-based episignature by Takeshi Mizuguchi, Nobuhiko Okamoto, Taiki Hara, Naoto Nishimura, Masamune Sakamoto, Li Fu, Yuri Uchiyama, Naomi Tsuchida, Kohei Hamanaka, Eriko Koshimizu, Atsushi Fujita, Kazuharu Misawa, Kazuhiko Nakabayashi, Satoko Miyatake, Naomichi Matsumoto

“…These signatures have generally been tested using methylation arrays, requiring additional experimental and evaluation costs. As an alternative, long-read sequencing can simultaneously and accurately evaluate genetic and epigenetic changes. …”
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From “open ocean” to “exposed aquaculture”: why and how we are changing the standard terminology describing “offshore aquaculture” by Tyler Sclodnick, Michael Chambers, Barry Antonio Costa-Pierce, Barry Antonio Costa-Pierce, Tobias Dewhurst, Nils Goseberg, Nils Goseberg, Kevin Gerald Heasman, Wolf Isbert, Gesche Krause, Daniel Wieczorek, Till Markus, Bela H. Buck, Bela H. Buck

“…The indices do not provide a definitive answer as to the potential financial success of a site as this requires other inputs relating to infrastructure costs, annual production, distance from port, sales strategy, etc. …”
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Targeted next-generation sequencing: a promising approach for Mycobacterium tuberculosis detection and drug resistance when applied in paucibacillary clinical samples by Wenting Jin, Meixia Wang, Yang Wang, Beidi Zhu, Qingqing Wang, Chunmei Zhou, Pei Li, Chaohui Hu, Jun Liu, Jue Pan, Jiachang Chen, Bijie Hu

“…The tNGS assay used in this study costs USD 96 and has a 12 hour turnaround time. Nonetheless, tNGS has a great deal of promise for enhancing TB detection while also addressing DR strains.…”
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Modeling maize growth and nitrogen dynamics using CERES-Maize (DSSAT) under diverse nitrogen management options in a conservation agriculture-based maize-wheat system by Kamlesh Kumar, C. M. Parihar, H. S. Nayak, D. R. Sena, Samarth Godara, Rajkumar Dhakar, Kiranmoy Patra, Ayan Sarkar, Sneha Bharadwaj, Prakash Chand Ghasal, A. L.Meena, K. Srikanth Reddy, T. K. Das, S. L. Jat, D. K. Sharma, Y. S. Saharawat, Upendra Singh, M. L. Jat, M. K. Gathala

“…Abstract Agricultural field experiments are costly and time-consuming, and often struggling to capture spatial and temporal variability. …”
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Genomic Prediction of Kernel Water Content in a Hybrid Population for Mechanized Harvesting in Maize in Northern China by Ping Luo, Ruisi Yang, Lin Zhang, Jie Yang, Houwen Wang, Hongjun Yong, Runze Zhang, Wenzhe Li, Fei Wang, Mingshun Li, Jianfeng Weng, Degui Zhang, Zhiqiang Zhou, Jienan Han, Wenwei Gao, Xinlong Xu, Ke Yang, Xuecai Zhang, Junjie Fu, Xinhai Li, Zhuanfang Hao, Zhiyong Ni

“…Genomic prediction enables rapid selection of maize varieties with low kernel water content (KWC), facilitating the development of mechanized maize harvesting and reducing costs. This study evaluated and characterized the KWC and grain yield (GY) of hybrid maize in northern China and used genomic prediction to identify superior hybrid combinations with low kernel water content at maturity (MKWC) and high GY adapted to northern China. …”
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Malaria parasite burden and heterogeneity of risk factors among Central African Republic refugees: a cross-sectional study in the Gado-Badzere refugee camp in Eastern Cameroon by Zidedine Nematchoua Weyou, Felicite Djemna Djieyep, Rene Ning Teh, Michel Lontsi-Demano, Cheikh Cambel Dieng, Roland Bamou, Eugenia Lo, Helen Kuokuo Kimbi, Helen Kuokuo Kimbi, Irene Ule Ngole Sumbele

“…Demographic characteristics, malaria risk factors, treatment-seeking behaviors and costs to cure malaria were assessed using semi-structured questionnaires.ResultsOf the 1,304 participants, 525 (40.3%) were malaria parasite positive with moderate geometric mean parasite density (GMPD) of 1100 parasites/μl of blood. …”
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Surgeon Sex and Postoperative Resource Utilization: A Population-Based Cohort Study by Kiyan Heybati, BHSc, Raj Satkunasivam, MD, MS, Khatereh Aminoltejari, MD, MSc, FRCSC, Hannah S. Thomas, MBChB, MS, Arghavan Salles, MD, PhD, Natalie Coburn, MD, MPH, Frances C. Wright, MD, Med, FRCSC, Lesley Gotlib Conn, PhD, Amy N. Luckenbaugh, MD, Sanjana Ranganathan, MD, Carlos Riveros, MD, Jason Sutherland, PhD, Colin McCartney, MBChB, PhD, FRCA, FFARCSI, FRCPC, Kathleen Armstrong, MD, MSc, FRCSC, Barbara Bass, MD, Allan S. Detsky, MD, PhD, CM, Angela Jerath, MD, MSc, Christopher J. D. Wallis, MD, PhD

“…Prior studies have shown that patients of female physicians experience better outcomes and have lower healthcare costs compared with patients of male physicians. …”
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Rubber Crumb Infill in Synthetic Turf and Health Outcomes: A Review of the Literature on Polycyclic Aromatic Hydrocarbons and Metalloids by Shamshad Karatela, Igor Popovic, Zahra Sobhani, Shiv Basant Kumar, Thava Palanisami, Li-Zi Lin, Gunther Paul

“…Synthetic turf has become a popular alternative to natural grass due to low upkeep costs; however, its health impacts have not been clearly elucidated. …”
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Prevalence of chronic kidney diseases among people living with HIV in Ethiopia: a systematic review and meta-analysis by Bruktawit Eshetu, Alemu Gedefie, Zewudu Mulatie, Ermiyas Alemayehu, Melaku Ashagrie Belete, Saba Gebremichael Tekele, Daniel Gebretsadik Weldehanna, Hussen Ebrahim, Mihret Tilahun, Habtu Debash, Agumas Shibabew, Ousman Mohammed

“…Further, as CKD is acknowledged as a major global public health issue affecting productivity, health, and healthcare costs, the goal of this systematic review and meta-analysis was to ascertain the pooled prevalence of CKD among people living with HIV in Ethiopia. …”
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Maximising Embedded Pharmacists in AGed CAre Medication Advisory Committees (MEGA-MAC): protocol for implementing Australia’s new guiding principles for medication management in re... by Amanda J. Cross, Brooke Blakeley, Kate Laver, Terry P. Haines, Sarah N. Hilmer, Atish Manek, Alexandra Bennett, Angelita Martini, Lyntara Quirke, Mary Ann Kulh, Sara L. Whittaker, Dayna R. Cenin, Anthony Hobbs, Joanne Money, Karina Rieniets, Kris Salisbury, Alene Sze Jing Yong, J. Simon Bell

“…A net benefit analysis will be conducted to examine the relative costs and benefits of implementing the intervention. …”
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DeintensiF: Standard versus individualized deintensified follow-up after curative treatment in head and neck cancer: protocol of a randomized pilot study by M. Mueller, M. Visini, S. A. Mueller, T. Stadler, G. P. Rajan, G. B. Morand, S.-L. Hool, D. H. Schanne, P. Balermpas, A. Limacher, S. Chan, S. Trelle, O. Elicin, R. Giger

“…However, routine follow-up involves social and financial burdens, including frequent imaging associated with radiation exposure and costs. Currently, there is no consensus on the follow-up strategy after HNC treatment, and no conclusive evidence shows a survival advantage for routine follow-up over symptom-driven self-referrals. …”
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Low-activity [18F]-somatostatin receptor (SSTR) imaging using [18F]SiTATE on a long axial field-of-view PET/CT scanner by Nils F. Trautwein, Eduardo Calderón, Pia M. Linder, Gerald Reischl, Philippe Driessen, Wenhong Lan, Andreas S. Brendlin, Thorben Groß, Helmut Dittmann, Martina Hinterleitner, Christian la Fougère, Fabian P. Schmidt, Lena S. Kiefer

“…Abstract Purpose 18F-labelled somatostatin receptor tracers have recently gained popularity due to their better spatial resolution, longer half-life and lower costs compared to 68Ga-labeled tracers. The aim of this study was to evaluate the impact and limitations of reduced administered activities of [18F]SiTATE on image quality, lesion detectability and quantitative PET parameters in a long axial field-of-view (LAFOV) PET/CT scanner. …”
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Clinical effect analysis of unilateral percutaneous vertebral cement distribution in the repair of osteoporotic thoracolumbar vertebral compression fractures by Liu Yuntao, Abuduwupuer Haibier, Aiben Kayierhan, Ma Liang, Yimuran Abudukelimu, Alimujiang Aximu, Tuerhongjiang Abudurexiti, Meng Xiangyu

“…The basic information of patients, surgery-related indicators including operation time, total hospitalization costs, postoperative hospitalization time, cement injection volume, visual analog scale (VAS) for back pain, Oswestry Disability Index (ODI) for back pain, vertebral height restoration rate, local kyphotic angle of the vertebra, and incidence of re-fracture of injured and adjacent vertebrae were compared between the two groups, and the follow-up results of all patients were recorded. …”
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Total neoadjuvant therapy based on short-course radiotherapy versus standard long-course chemoradiotherapy for locally advanced rectal cancer: a systematic review and meta-analysis... by Wenji Pu, Wenji Pu, Wenji Pu, Wenqi Chen, Haiman Jing, Jishi Li, Yong Jiang, Shasha Li, Weijie Wen, Zhiyuan Xu, Jing Jin

“…Moreover, survival outcomes, distant recurrence rate, and surgical indicators were comparable between the two groups.ConclusionFor LARC patients, the SCRT/CCT regimen not only has a higher pCR rate, equivalent OS, and comparable additional indicators versus standard LCCRT but also shortens the treatment time, costs less, and improves patients’ adherence to the innovative anti-tumor therapy; hence, with the concept of acute toxicity control, it could be further widely and safely utilized, especially in resource-limited settings.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/, identifier CRD42024600180.…”
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Socio-economic contextual determinants and behavioral changes during pregnancy: evidence from the "MAMI-MED" cohort by Francesca Bitonti, Angelo Mazza, Martina Barchitta, Andrea Maugeri, Roberta Magnano San Lio, Giuliana Favara, Claudia La Mastra, Maria Clara La Rosa, Fabiola Galvani, Elisa Pappalardo, Carla Ettore, Giuseppe Ettore, Federico Mertoli, Carmela Elita Schillaci, Antonella Agodi

“…Geocoding techniques were employed to link individual-level data to selected contextual variables related to education, income, unemployment, and housing costs in the participants' residential areas. Mann–Whitney test, Kruskal–Wallis tests, logistic regressions and mixtures of regressions models with concomitant variables are implemented 1) to investigate the associations between contextual covariates and individual responses, 2) to assess the presence of latent sub-groups of the population reacting differently to the same contextual factors. …”
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Urban Tree Canopy Mapping and Analysis Using Iterative Annotation Method and Deep Learning: A Case Study in Beijing by Yulong Ding, Ximin Cui, Zhengchao Chen, Zeqing Wang, Debao Yuan, Xiang Meng, Xuan Yang, Yue Xu, Xiangyu Tian

“…Deep learning models typically require large amounts of labeled data for training, but manually annotating pixel-level labels is time-consuming and costly. To address this, we propose an iterative method based on intersection over union (IoU), integrating multiscale segmentation and nearest-neighbor classification algorithms. …”
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