Optimised and rapid pre-clinical screening in the SOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis (ALS). by Richard J Mead, Ellen J Bennett, Aneurin J Kennerley, Paul Sharp, Claire Sunyach, Paul Kasher, Jason Berwick, Brigitte Pettmann, Guiseppe Battaglia, Mimoun Azzouz, Andrew Grierson, Pamela J Shaw

“…Such an approach will increase throughput for reduced costs, whilst reducing the severity of the experimental procedures involved.…”
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Expectations Exceeded by William Cathcart-Rake, Tyler Hughes

“…Ninety-two (81.4%) of the matriculants were from rural communities, and 47.4% of matriculants received Kansas Medical Student (KMS) loans to help defray medical school costs. Fifty-five of 81 graduates (67.9%) entered primary care residencies (48.1% in family medicine, 7.4% in pediatrics, and 12.3% in internal medicine). …”
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Enhancing international trade competencies through local field trips: a study of Colombian undergraduate students by Florentino Rico, Heidy Rico, Mario de La Puente, Jose Torres, Hernan Guzman

“…While limited by sample size and short-term focus, the study demonstrates that carefully designed local field trips can serve as effective alternatives to costly international experiences in developing crucial global career skills, particularly in resource-constrained educational settings. …”
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Electrocardiographic Discrimination of Long QT Syndrome Genotypes: A Comparative Analysis and Machine Learning Approach by Martina Srutova, Vaclav Kremen, Lenka Lhotska

“…Differentiating LQTS genotypes is crucial for targeted management and treatment, yet conventional genetic testing remains costly and time-consuming. This study aims to improve the distinction between LQTS genotypes, particularly LQT3, through a novel electrocardiogram (ECG)-based approach. …”
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The impact of the formal rationalization of healthcare on physician clinical teaching in a United States academic medical center by David A. Rogers, Katherine A. Meese, Cindy L. Cain

“…Abstract Background Formal rationalization is the process whereby an organization achieves the greatest efficiency through the control of work and is occurring in the United States as an effort to control healthcare costs. This study aimed to explore the McDonaldization thesis’s impact, a contemporary form of formal rationalization, on the academic physicians teaching in a clinical setting where patient care is also being delivered. …”
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Energy Use in Rural Kenyan Households: A Case Study on the Welfare Impact of Rural Electrification by Jacob Chege

“…Further, inter-fuel substitution is hampered by unfavourable electricity tariffs and costly electric appliances for cooking. Although connected households enjoy social benefits attributed to electricity use, its consumption in the study area is low, and the range of electricity-dependent activities is narrow. …”
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Coexistence of Asymptomatic Allergic Bronchopulmonary Aspergillosis and Active Pulmonary Tuberculosis: Case Report by Jia Q, Wang L, Tong X, Sun J, Fan H

“…To obtain a clear diagnosis, she visited multiple hospitals and incurred substantial time and financial costs. Active tuberculosis was initially confirmed using specialized detection methods, including metagenomic next-generation sequencing and Xpert MTB/RIF analysis of bronchoalveolar lavage fluid. …”
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Chronic Kidney Disease in the Eastern Region of the State of Mexico: Implication of the Social Determinants of Health by Luis Enrique Hernández Gamundi, Donovan Casas Patiño, Alejandra Rodríguez Torres, Angélica Heredia Sánchez

“…<br /><strong>Results:</strong> the voice of the disease is relegated to be devastating in its attention and way of living; income due to constant travel, medical care costs and unemployment conjugates a deadly trap that conditions the economic fragmentation of the patient; public policies are unattainable -referring to the transplant program-; culture shows a religious symbolism of protection to the health coupled with social stigmatization for suffering chronic kidney disease CKD; the health system transits in lack of service guarantees -dialysis, hemodialysis, lack of supplies-; gender shows equality in care but overload of women in patient care. …”
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Efficient Segmentation Using Attention-Fusion Modules With Dense Predictions by Serdar Erisen

“…Fusing the multi-scale global and local semantic information remains a challenging task for foundation models with computational costs and the need for effective long-range recognition. …”
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Idle occupancy and dead piles: new challenges in public charging station promotion by Mushu Zhao, Dawei Wang, Weifeng Li

“…A mismatch exists between high construction costs, low utilisation rates, an expanding market size and increasing charging demand. …”
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Integrating generative AI and machine learning classifiers for solving heterogenous MCGDM: a case of employee churn prediction by Hagar G. Abu-Faty, Ahmed Kafafy, Mohiy M. Hadhoud, Osama Abdel-Raouf

“…High turnover rates increase recruitment and training costs, and disrupt workflows, making it a top concern for institutions aiming to maintain stability, growth and continuity. …”
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Precision agriculture for improving crop yield predictions: a literature review by Sarmistha Saha, Olga D. Kucher, Aleksandra O. Utkina, Nazih Y. Rebouh

“…A key aim of precision agricultural technologies is to optimize crop yield and quality, while also working to lower operating costs and minimize environmental impact. This approach not only enhances productivity but also promotes sustainable farming practices. …”
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Determinants of climate change adaptation strategies among rural household farmers in the Wolaita zone, Southern Ethiopia by Demissie Dalacho Debisa, Teshome Yirgu Bayu, Thomas Toma Tora

“…The problem confrontation index identified major barriers such as high costs of agricultural inputs, insufficient institutional support, and limited market access. …”
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Key Technologies in Intelligent O&M System Construction for Urban Rail Transit Communication by WANG Xianlei

“…[Objective] Aiming to design and construct a high-performance, high-reliability intelligent O&M (operation and maintenance) system for urban rail transit communication and to formulate scientific maintenance strategies, it is necessary to transform traditional periodic scheduled maintenance to condition-based maintenance according to test analysis, and to prior assessment-based predictive maintenance, thereby reducing the probability of equipment failure and operational costs. Furthermore, it is to shift from traditional manual O&M management to an automated, information-based intelligent monitoring and maintenance approach. …”
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A demand-centered scheduling framework for shared supercomputing resources: modeling, metrics, and case insights by Hyungwook Shim

“…However, limited infrastructure capacity and rising construction costs have made traditional supply-side expansion strategies increasingly unsustainable. …”
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SFSIN: A Lightweight Model for Remote Sensing Image Super-Resolution with Strip-like Feature Superpixel Interaction Network by Yanxia Lyu, Yuhang Liu, Qianqian Zhao, Ziwen Hao, Xin Song

“…Remote sensing image (RSI) super-resolution plays a critical role in improving image details and reducing costs associated with physical imaging devices. However, existing super-resolution methods are not applicable to resource-constrained edge devices because they are hampered by a large number of parameters and significant computational complexity. …”
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Cross-border e-shopping on e-commerce B2C multi-sided digital platforms: Antecedents and moderating role of country of location by Marzanna K. Witek-Hajduk, Anna Grudecka

“…Chinese MSPs regarding the influence of payment security on ease of use and influence on trust in a foreign MSP of the following antecedents: consumer service on a given MSP, its reputation, and perception of prices/costs. Implications & Recommendations: This article offers valuable insights into e-consumer behaviour useful to MSPs’ managers. …”
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Evolution from the physical process-based approaches to machine learning approaches to predicting urban floods: a literature review by Md Shike Bin Mazid Anik, Chunjiang An, S. Samuel Li

“…Open-source tools, public education, and better planning are also needed to make cities safer and more resilient to costly floods.…”
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Impact of digital technology on farmland transfer and food security: an empirical study in rural China by Xinyu Guo, Xianghua Liu, Jinwei Lv, Ruojia Zhu

“…The potential mechanisms are the resource reallocation effect triggered by increased non-farm employment and income, the efficiency-enhancing effect of agricultural production driven by digital technology, and the transaction facilitation effect brought about by lower information costs. Heterogeneity analysis shows that in terms of policy support, the increase of grain purchase price and direct subsidy positively regulate the willingness to transfer; In terms of farmers’ capital endowment, the groups with high human capital and physical capital are more inclined to transfer out of farmland, while the households with high land capital show the characteristics of farmland dependence, and the households with high information capital have a stronger willingness to transfer farmland; In terms of economic and cultural attributes, farmers located in agricultural areas, underdeveloped areas and traditional villages also have stronger willingness to transfer farmland. …”
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Experimental evolution of a pathogen confronted with innate immune memory increases variation in virulence. by Ana Korša, Moritz Baur, Nora K E Schulz, Jaime M Anaya-Rojas, Alexander Mellmann, Joachim Kurtz

“…Theory predicts that the way virulence evolves depends on the balance between the benefits and costs it provides to pathogen fitness. Additionally, host responses to infections, such as resistance or tolerance, play a critical role in shaping virulence evolution. …”
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