Mechanical Design and Motion Analysis of a Hybrid Robot for Equine Rehabilitation by YE Zenglin, DAI Zhonghong, ZHANG Liang'an, WEI Liangguo, CHEN Hua

“…Furthermore, challenges related to individual variations and the requirement for specialised therapist training need to be addressed, alongside cost, resource, and training concerns, to ensure wider adoption of equine therapy. …”
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Three Asparagine insertions in the K13-propeller led to Plasmodium falciparum becoming resistant to multiple antimalarial drugs by Zheng Xiang, Mengxi Duan, Siqi Wang, Hui Zhao, Wei Zhao, Xiaosong Li, Xinxin Li, Weilin Zeng, Yanrui Wu, Fuxue Yang, Xinyu Liu, Cong Tang, Liwang Cui, Zhaoqing Yang

“…Additionally, 3N-3D7 exhibited a fitness defect, with the proportion decreasing gradually during co-culture with 3D7, its fitness cost calculated as 14.88 ± 2.87. All these results support the opinion that the insertion of three asparagines was a molecular marker of resistance to artemisinin derivatives, Pyronaridine Phosphate, and Naphthoquine in P. falciparum.…”
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Humic acid from leonardite for cadmium adsorption and potential applications by MENG Fande, YUAN Guodong, WEI Jing, BI Dongxue, WANG Hailong, LIU Xingyuan

“…Leo-HA has the advantages of low cost, high adsorption capacity, and low Cd content, thus it is a prospective adsorbent for immobilizing Cd²⁺ in contaminated soils or removing Cd²⁺ from water. …”
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Results of a feasibility study of the FReSH START intervention to improve quality of life and other outcomes in people who repeatedly self-harm (Function REplacement in repeated Se... by Bethan Copsey, Alexandra Wright-Hughes, Amanda Farrin, Cara Gates, Kate Farley, Cathy Brennan, Dean McMillan, Christopher D. Graham, Chris Bojke, Richard Mattock, Adam Martin, Petra Bijsterveld, Judith Horrocks, Suzanne Hartley, Marsha McAdam, Dafydd Hammond-Jones, Louise D. Bryant, Allan House, Elspeth Guthrie, the FReSH START lived experience group

“…Multiple repetition bears a significant cost to individuals and healthcare systems. A recent Cochrane review showed little evidence for the benefit of existing psychological therapies for people who repeatedly self-harm. …”
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Development of a PCR-dipstick DNA chromatography-based tool for the detection of CTX-M- and TEM-producing Escherichia coli and Klebsiella pneumoniae isolated from patients in Kafue... by Misheck Shawa, Kyoko Hayashida, Naganori Nao, Atmika Paudel, Harvey Kamboyi, Herman Chambaro, Malala Mulavu, Cynthia Sipho Khumalo, Mike Nundwe, Tuvshinzaya Zorigt, Chinatsu Nakamura, Yongjin Qiu, Naoko Kawai, Maisa Kasanga, Joseph Chizimu, Lavel Moonga, Joseph Ndebe, Manyando Simbotwe, Shohei Ogata, Mulemba Samutela, Chie Nakajima, Roma Chilengi, Mable Mutengo, Masahiro Kajihara, Hirofumi Sawa, Bernard Hang’ombe, Yasuhiko Suzuki, Hideaki Higashi

“…This study aimed to develop a rapid, cost-effective tool for the genotypic surveillance of 3GC resistance. …”
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In situ formation of solid electrolyte interphase facilitates anode-free aqueous zinc battery by Mingming Wang, Jiale Ma, Yahan Meng, Peiyan Tong, Ruihao Luo, Dongyang Shen, Xinhua Zheng, Na Chen, Mingying Zhang, Li Song, Ziqi Zhang, Dongjun Li, Chengming Wang, Hao Cheng, Yingying Lu, Zhenyu Li, Wei Chen

“…These results indicate that the design of desirable SEI compositions could pave the way for developing low-cost, high-performance anode-free AZBs.…”
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Legume-based green concentrate alleviates negative energy balance and enhances performance, metabolic health, and profitability in postpartum Holstein Friesian cows by Renny Fatmyah Utamy, Ambo Ako, Zyahrul Ramadan, Yasuyuki Ishii, Mohammad Mijanur Rahman, Kannika Umpuch, Azisah Nurfadilah, Gemal Umar Akmal Alkatiry, Muhammad Akram, Jiant Muthahra Maharani

“…Results: GC30 significantly improved milk yield (15.88 kg/d), FCE (1.10), and daily profit (United States Dollars 10.99/d), while reducing feed costs and BHB levels in blood (0.91 mmol/L) and milk (0.43 mmol/L) compared to CON (p < 0.05). …”
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Towards the Integration of Additive Manufacturing for Freeform Steel and Glass Façade Construction by Lia Tramontini

“…This type of construction involves the design, fabrication, and assembly of complex components, which requires close interdisciplinary collaboration to realize the architectural vision of the designer and achieve good façade performance while also striving for efficiency in design, material use, fabrication, construction, and cost. Recent developments in additive manufacturing technology are making AM a more efficient, reliable, and accessible fabrication strategy for a range of different industries, scales, and materials. …”
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Comprehensive Evaluation of Several Treatment Combinations Used to Manage Acute Respiratory Infections in Routine Paediatric Practice by E. G. Kondyurina, A. L. Zaplatnikov, T. N. Yelkina, E. I. Burtseva, O. A. Gribanova, N. I. Pirozhkova, G. A. Mingalimova, I. O. Tyuleneva, S. V. Trushakova, E. A. Mukasheva

“…In addition, visit 3 included the assessment of the volume and cost of treatment in conjunction with clinical benefit and treatment safety/tolerability (as judged by the physicians and parents). …”
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Descriptions of self-treatment for the middle-aged and elderly in Shanxi, China. by Rui Wang, Chenjin Ma, Kun Jiang, Ming Li, Shuangge Ma

“…The subjects with a junior high education (p-value < 0.001, aOR = 0.049) and senior high education (p-value = 0.020, aOR = 0.146) had a lower probability of using insurance. For both total costs and out-of-pocket costs, subjects who were 51 to 60 years old had lower costs. …”
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Development of a Consensus-based Agenda to Identify Priorities for Clinical Research in Pediatric Orthopaedic Surgery by A. Noelle Larson, MD, Ria Paradkar, Matthew Schmitz, MD, Raymond Liu, MD, Neeraj M. Patel, MD, MPH, MBS, Henry Ellis, MD, Todd A. Milbrandt, MD, Dan Sucato, MD, Kevin Shea, MD, Jennifer Laine, MD

“…Key Concepts: (1) Despite the significant burden and cost of pediatric musculoskeletal conditions, pediatric orthopaedic research receives low research funding, underscoring the need for a focused research agenda. (2) This study used a modified Delphi process to engage pediatric orthopaedic surgeons across multiple pediatric orthopaedic subspecialties in the development of a consensus-based research agenda in order to identify high-priority clinical questions. (3) The final agenda reflects critical gaps in pediatric orthopaedic care, including conditions that impact long-term function and quality of life in pediatric orthopaedic patients. (4) The final agenda aims to guide future research, foster multicenter collaboration, and advocate optimized allocation of funding to improve evidence-based pediatric orthopaedic care. …”
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A Randomized Controlled Trial Comparing Automated Peritoneal Dialysis and Hemodialysis for Urgent-Start Dialysis in ESRD by Haijiao Jin, Wei Fang, Ling Wang, Xiujuan Zang, Yueyi Deng, Guoqing Wu, Ying Li, Xiaonong Chen, Niansong Wang, Gengru Jiang, Zhiyong Guo, Xiaoxia Wang, Yinghui Qi, Shifan Lv, Zhaohui Ni

“…In terms of health economics, the total direct medical cost of the initial hospitalization for patients with ESRD was significantly lower in the APD group (27,008.39 CNY) than in the HD group (42,597.54 CNY) (P = 0.001), whereas the duration of the first hospital stay showed no significant difference (P = 0.424). …”
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Single-Inhaler Triple Therapy in Primary Care Across Europe: Expert Panel Consensus on the Consequences of Payer-Driven Access Rules and Call to Action by Di Marco F, Shahaj O, Valipour A, Legrand B, Jommi C, Micheletto C, Vogelmeier CF, Freeman D, Kocks JWH, Alves L, Rubio MC, Peché R, Palkonen Snr S, Winders T, Roche N

“…The expert panel generated seven consensus points stating that enabling PCPs to step up or switch eligible patients to SITT has the potential to support care continuity, enhance clinical autonomy for PCPs, reduce reliance on potentially less effective treatment options, improve patient and healthcare system outcomes, avoid unnecessary referrals to specialists, enable prompt initiation of guideline-directed medical therapy for COPD in primary care and reduce access inequalities.Conclusion: Restrictions for SITT initiation in primary care may need to be revisited to mitigate their unintended health and cost consequences and improve equitable access to treatment. …”
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A Novel You Only Listen Once (YOLO) Deep Learning Model for Automatic Prominent Bowel Sounds Detection: Feasibility Study in Healthy Subjects by Rohan Kalahasty, Gayathri Yerrapragada, Jieun Lee, Keerthy Gopalakrishnan, Avneet Kaur, Pratyusha Muddaloor, Divyanshi Sood, Charmy Parikh, Jay Gohri, Gianeshwaree Alias Rachna Panjwani, Naghmeh Asadimanesh, Rabiah Aslam Ansari, Swetha Rapolu, Poonguzhali Elangovan, Shiva Sankari Karuppiah, Vijaya M. Dasari, Scott A. Helgeson, Venkata S. Akshintala, Shivaram P. Arunachalam

“…Use of artificial intelligence (AI) and improvements in computational analysis can enhance the use of PEGs in different GI diseases and lead to a non-invasive, cost-effective diagnostic modality that has not been explored before. …”
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One-Year Monitoring of the Evolution of SARS-CoV-2 Omicron Subvariants Through Wastewater Analysis (Central Italy, August 2023–July 2024) by Alessandra Nappo, Maya Petricciuolo, Giulia Berno, Agnese Carnevali, Cesare Ernesto Maria Gruber, Giulia Bicchieraro, Roberta Spaccapelo, Martina Rueca, Fabrizio Carletti, Pietro Giorgio Spezia, Carolina Veneri, Giuseppina La Rosa, Elisabetta Suffredini, Daniele Focosi, Giovanni Chillemi, Ermanno Federici, Fabrizio Maggi

“…Wastewater surveillance has proven to be a cost-effective, non-invasive method for monitoring the spread and evolution of SARS-CoV-2, yet its value during today’s low-incidence phase is still being defined. …”
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Healthcare systems and health economics in GCC countries: informing decision-makers from the perspective of the Gulf health economics association by Yazed AlRuthia, Sara Aldallal, Hana A. Al-Abdulkarim, Hana A. Al-Abdulkarim, Ahmed Al-jedai, Ahmed Al-jedai, Hajer Almudaiheem, Anas Hamad, Anas Hamad, Khalifa Elmusharaf, Mouza Saadi, Hamda Al Awar, Haleama Al Sabbah, Suliman Alghnam, Mohamed Al Ghamdi, Sarah S. Monshi, Nada AlAgil, Mohamed Ebrahim Al Khalifa, Qasim Abdulkarim, Sawsan Abdulkarim, Huda Jawad, Sultana Al-Sabahi, Asiya Al Kindi, Said Wani, Abdullah Alibrahim, Abdullah Alibrahim

“…The convened experts also underscored the importance of collaboration among GCC member states to enhance the adoption of robust health technology evaluations and improve patient access to cost-effective treatments.…”
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Primary health care data-based early warning system for dengue outbreaks: a nationwide case study in BrazilResearch in context by Rejane Santos-Silva, Pilar Tavares Veras Florentino, Thiago Cerqueira-Silva, Vinicius de Araújo Oliveira, Juracy Bertoldo Junior, George C.G. Barbosa, Gerson O. Penna, Viviane S. Boaventura, Pablo I. Pereira Ramos, Manoel Barral-Netto, Izabel Marcilio

“…Primary health care (PHC) administrative data applied to syndromic surveillance offers a cost-effective way to integrate early warning systems (EWS). …”
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Unlocking renewable energy potential: Overcoming knowledge sharing hurdles in rural EU regions on example of poland, sweden and france. by Justyna Żywiołek, Radosław Wolniak, Wieslaw Wes Grebski, Sunil Tiwari, Marek Matuszewski, Adam Koliński

“…Key findings reveal that while environmental awareness is high, significant barriers persist in the form of limited knowledge, underdeveloped infrastructure, and perceptions of high costs associated with RES. In Poland, 76% of respondents expressed a positive view of RES but cited concerns about cost and security. …”
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Obtaining and Characterization of Experimental Diagnostic Brucellosis Rabbit Sera for the Development of a National Standard for Brucellosis Serum by L N. Tuychiev, B. M. Tadjiev, N. U. Tadjieva, O. Sh. Kasimov, A. M-T. Bektimirov, A. P. Yusupov, J. A. Anvarov, B. V. Shukurov

“…However, due to the lack of a national standard serum in the country and the high cost of analog standard serums on the market, problems may arise in the production of diagnostic tools. …”
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Exploration of Practical Experience in Socialized Operation of the Chaoyang Section of Wenyu River Park by Zehui SUN, Yudi LIU, Jiali WU, Xiao FENG

“…The market-oriented operation mechanism ensures that the operation projects obtain reasonable returns in a market-oriented manner and balances the cost expenditure of the park. The in-depth community participation mechanism has encouraged residents to deeply engage in the development of the park and promoted social integration. …”
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