Diversity of Bioactive Compounds in Microalgae: Key Classes and Functional Applications by Maslin Osathanunkul, Suebsuya Thanaporn, Lefkothea Karapetsi, Georgia Maria Nteve, Emmanouil Pratsinakis, Eleni Stefanidou, Giorgos Lagiotis, Eleni Avramidou, Lydia Zorxzobokou, Georgia Tsintzou, Artemis Athanasiou, Sofia Mpelai, Constantinos Constandinidis, Panagiota Pantiora, Marián Merino, José Luis Mullor, Luka Dobrovic, Leonardo Cerasino, Tomohisa Ogawa, Meropi Tsaousi, Alexandre M. C. Rodrigues, Helena Cardoso, Rita Pires, Daniel Figueiredo, Inês F. Costa, Catarina Anjos, Nikolaos E. Labrou, Panagiotis Madesis

“…The GRAS status of several species facilitates market integration, but challenges in scaling and cost reduction remain. Advances in biotechnology and metabolic engineering will optimize production, driving growth in the global microalgae industry. …”
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Enhancing drought tolerance in Pisum sativum and Vicia faba through interspecific interactions with a mixed inoculum of Rhizobium laguerreae and non-host beneficial rhizobacteria by Asma Hami, Imane El Attar, Imane El Attar, Najoua Mghazli, Najoua Mghazli, Salah Ennajeh, El Houcine Ait-Ouakrim, Meryeme Bennis, Meryeme Bennis, Said Oulghazi, Bouabid Badaoui, Bouabid Badaoui, Jamal Aurag, Laila Sbabou, Kaoutar Taha

“…IntroductionHarnessing plant growth-promoting rhizobia presents a sustainable and cost-effective method to enhance crop performance, particularly under drought stress. …”
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Beyond BMI: a comprehensive approach to pediatric obesity assessment by Norma Cipatli Ayuzo Del Valle, Norma Cipatli Ayuzo Del Valle, Perla Pérez-Treviño, Ana Carla Cepeda Lopez, Ana Carla Cepeda Lopez, Regina M. Murillo-Torres, Elena Cristina Castillo, Diego Gutierrez-Cantu, Oscar Tamez-Rivera, Oscar Tamez-Rivera, Mayela Paez Flores, Isabella Flores-Ayuzo, Luis Alberto Luévano-Martinez, Sergio Javier Fernandez Ortiz, Sergio Javier Fernandez Ortiz, Noemí García, Leonardo Mancillas-Adame

“…Although bioelectrical impedance analysis was selected due to its practicality, cost-effectiveness, and non-invasiveness, it has inherent measurement variability compared to dual-energy x-ray absorptiometry. …”
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Evaluating the Fiscal Impact of Antiretroviral Therapy for the Management of HIV in the United States 1987–2023 by Paquete AT, Mordi U, Jarrett J, Thaliffdeen R, Chaudhari P, Connolly MP, Kotsopoulos N, Sullivan PS

“…The reduction of healthcare costs for HIV care financed by the government was also considered. …”
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Digital education and exercise therapy versus minimal intervention for young people at high risk of early onset knee osteoarthritis after ACL reconstruction: a study protocol for t... by Jackie L. Whittaker, Amanda Cammalleri, Candice Archibald, Alexandra Brooks-Hill, Patrick Chin, Sarah Clark, Jennifer C. Davis, Alison M. Hoens, Michael A. Hunt, Karin Kausky, Angelina Ko, Lise Leveille, Linda C. Li, Parth Lodhia, Justin M. Losciale, Maxi Miciak, Amber D. Mosewich, Adnan Sheikh, Trish Silvester-Lee, Linda K. Truong, Dominic Wade, David R. Wilson, Hui Xie, Xian He Yan, Ewa M. Roos

“…We will also assess secondary implementation (perceived barriers and facilitators of SOAR delivery), secondary efficiency (incremental cost-utility ratio), and exploratory outcomes. Missing data will be imputed and blinded intention-to-treat analyses performed. …”
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Advanced strategy for cancer detection based on volatile organic compounds in breath by Ziqi Jia, Yiwen Jiang, Tongxuan Shang, Heng Cao, Jiayi Li, Lin Cong, Pengming Pu, Hengyi Xu, Yuchen Liu, Yansong Huang, Dongxu Ma, Jiang Wu, Ruijie Zhou, Xiang Wang, Chang bao Han, Jiaqi Liu

“…Abstract The analysis of volatile organic compounds (VOCs) in exhaled breath has emerged as a promising non-invasive approach for cancer diagnosis, offering advantages in speed, safety, cost-effectiveness, and real-time monitoring. Two primary methodologies are employed for VOCs detection: mass spectrometry (MS)-based techniques, which provide high-precision identification and quantification of individual compounds, and sensor-based pattern recognition methods, which detect disease-specific VOC signatures. …”
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Potential of digital applications for self-management and other outcomes in inflammatory rheumatic diseases: a systematic literature review by Alina Volkmar, Cay-Benedict von der Decken, Cay-Benedict von der Decken, Cay-Benedict von der Decken, Cay-Benedict von der Decken, Stefan Kleinert, Stefan Kleinert, Kirsten Karberg, Kirsten Karberg, Georg Gauler, Georg Gauler, Michael Klennert, Jana Klennert, Peer Malte Aries, Peer Malte Aries, Sonja Froschauer, Sarah Wildenhain, Theresia Muth, Susanna Späthling-Mestekemper, Susanna Späthling-Mestekemper, Christoph Kuhn, Christoph Kuhn, Wolfgang Vorbrüggen, Wolfgang Vorbrüggen, Martin Welcker, Martin Welcker, Peter Bartz-Bazzanella, Peter Bartz-Bazzanella, Matthias Englbrecht

“…Variability in study design, sample size, and intervention duration posed challenges for drawing definitive conclusions about the effectiveness of digital interventions.DiscussionDigital health applications show promise as cost-effective and scalable solutions to complement standard IRD care by empowering patients in their disease management. …”
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Clinical characteristic of isolated thrombocytopenia in patients with bone marrow failure-related germline variants: a retrospective study from a single centre by Nanxi Dong, Jingjie Dong, Chuanao Xin, Peicheng Wang, Yaonan Hong, Rudan Zheng, Zexing Sun, Qi Liu, Yingying Shen, Xiawan Yang, Yiping Shen, Jianping Shen, Baodong Ye, Yuhong Zhou, Dijiong Wu

“…While whole-exome sequencing (WES) detects these variants, its cost limits routine use. This study compares prognosis and clinical features of isolated thrombocytopenia in patients with ITGV-BMFsand those with classic ITP.Methods The clinical data of patients diagnosed with ITGV-BMFs were retrospectively analyzed and compared with those of patients with classic ITP from August 2018 to February 2024. …”
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Method for compensating multi-time measurement data of distribution network based on alternating minimization matrix completion combined with VMD-ARIMA-LSTM by Xiaodan Yu, Ruijia Jiang, Xiaolong Jin, Hongjie Jia, Yunfei Mu, Wei Wei, Wanxin Tang

“…However, the increasing complexity of network structure and the high installation cost of measurement equipment introduce operational challenges including state variability and measurement data incompleteness. …”
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Effect of four tillage methods on the physical properties and loss of soil in the potato–grass rotation in hillside areas of a high Andean region in Colombia Efecto de cuatro mét... by Ramírez Luís, Chaparro Anaya Oscar, Bernal Napoleón, Ipaz Sandro, Montealegre Guillermo

“…ATT generated the bigger cost–reducing and environmental retribution, because his production (13 tha<sup>–1</sup>) was major than the average obtained in the treatments (12.4 tha<sup>–1</sup>) and the lost one belonging to ground was minor than the generated for MT and CMT.…”
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Health Beliefs and Obesity Bias as Determinants of Attitudes Toward the Rising Tides of GLP-1 Medications: Mounjaro and Ozempic by Al-Mahzoum K, Abdelaziz DH, Alenezi F, Almutairi J, Alsubaiei MK, Alharbi AB, Al-Rawi S, Al-Rawi S, Bousheheri FF, Alhajri AH, Alajmi SN, Sallam M, Mansour NO, Alnazly EK, Sallam M

“…The negative attitudes observed likely reflect concerns about side effects, cost, and accessibility of these medications. The findings highlighted the need for targeted education in Arab countries to address obesity bias and encourage a balanced evaluation of the benefits and risks of GLP-1 drugs for weight management.Keywords: obesity BIAs, GLP-1 medications, mounjaro, ozempic, health beliefs, weight management, pharmacological interventions…”
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A comparative study of bone density in elderly people measured with AI and QCT by Min Guo, Min Guo, Yu Zhang, Yu Zhang, XinXin Gu, XinXin Gu, Xuhui Liu, Xuhui Liu, Fei Peng, Fei Peng, Zongjun Zhang, Zongjun Zhang, Mei Jing, Mei Jing, Yingxia Fu, Yingxia Fu

“…This technology enables cost-effective, radiation-free osteoporosis screening through routine CT repurposing, particularly beneficial for resource-constrained settings.…”
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Adherence to treatment for tuberculosis infection in children using a comprehensive care strategy: a prospective cohort study with a historical control groupResearch in context by Iader Rodríguez-Márquez, Dione Benjumea-Bedoya, Andrea Victoria Restrepo-Gouzy, Claudia Patricia Beltrán-Arroyave, Diana Marín, Fernando Nicolás Montes-Zuluaga, Juan Carlos Alzate-Ángel, Lina Marcela Cadavid-Álvarez, Lizeth Andrea Paniagua-Saldarriaga, Teresa Realpe, Yesenia Perea-Torres, Lisandra María Arango-García, Natalia Pérez-Doncel, María Patricia Arbeláez-Montoya, Jaime Robledo

“…Interpretation: The CCS increases adherence to treatment for TBI in children safely compared to SOC. Future cost-effectiveness studies will help implement this strategy in programmatic settings. …”
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Estudio de cumplimiento terapéutico y aceptación de cambios en hábitos saludables en pacientes intervenidos de revascularización coronaria by Delfina Fletcher-Sanfeliu, Laura Vidal, Fernando Enríquez, Rubén Tarrío, Daniel Padrol, Irene Hidalgo, Alcides José Velásquez, Marina Rigo, Ramon Lluis Barril, José Ignacio Sáez de Ibarra

“…RESUMEN: Introducción: La enfermedad cardiovascular es la principal causa de morbimortalidad a nivel mundial y su prevención es coste-eficaz. El objetivo del estudio es conocer el estado de los factores de riesgo cardiovascular modificables en los pacientes coronarios sometidos a cirugía coronaria para averiguar los puntos dónde se debe hacer mayor incisión para la mejora de la prevención secundaria y tratamiento de la cardiopatía isquémica. …”
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Al–Si alloyed uncoated hot stamping steels for enhanced oxidation resistance by Zhaoqi Song, Kaixun Wang, Haitao Zhao, Long Ma, Junheng Gao, Honghui Wu, Yuhe Huang, Chaolei Zhang, Jun Lu, Shuize Wang, Xinping Mao

“…This research not only addresses a critical gap in the literature but also offers a cost-effective strategy for enhancing the oxidation resistance of hot stamping steels, contributing to the broader goals of lightweight vehicle design and carbon emission reduction.…”
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Water, Health, and Social Technologies: One Million Cisterns Programme Case Study by José Firmino de Sousa Filho, Walisson Angélico de Araújo, Mariana Sebastião, Adalton Fonseca, Raíza Tourinho, Denise Pimenta, Gervásio Santos, Lucas Emanuel, Roberto F. S. Andrade, Gustavo Casais, Gisele Paixão, Andrea Ferreira, Rachel Coelho, Maria Yuri Ichihara, Júlia Pescarini, Joanna M. N. Guimarães, Paulo Victor da Costa, Ismael Silveira, Rafael Silva, Rita Ribeiro, Maurício L. Barreto, On behalf of the SEDHI team

“…It specifically examines the semi-arid region of Brazil, where the introduction of a social climate adaptation tool, cisterns, has brought about significant positive changes. Cisterns, a low-cost climate adaptation technology, can be replicated globally, reducing the negative health impacts of frequent droughts, especially for vulnerable groups in remote rural areas. …”
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Transarterial Embolization and Percutaneous Ethanol Injection as an Effective Bridge Therapy before Liver Transplantation for Hepatitis C-Related Hepatocellular Carcinoma by Marcio F. Chedid, Leandro A. Scaffaro, Aljamir D. Chedid, Antonio C. Maciel, Carlos Thadeu S. Cerski, Matheus J. Reis, Tomaz J. M. Grezzana-Filho, Alexandre de Araujo, Ian Leipnitz, Cleber D. P. Kruel, Mario R. Alvares-da-Silva, Cleber R. P. Kruel

“…Transarterial chemoembolization alone or in association with radiofrequency ablation is an effective bridging strategy for patients with hepatocellular carcinoma awaiting for a liver transplant. However, cost of this therapy may limit its utilization. This study was designed to evaluate the outcomes of a protocol involving transarterial embolization, percutaneous ethanol injection, or both methods for bridging hepatocellular carcinomas prior to liver transplantation. …”
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Effects of partial soybean meal replacement with sunflower meal and non-starch polysaccharide degrading enzymes supplementation on broiler growth performance, nutrient digestibilit... by Zeeshan Munawar, Saad Amjid, Faisal Ramzan, Azhar Rafique, Safdar Hassan, Urooj Anwar, Momna Mehmood, Umar Farooq, Muhammad Farooq Khalid, Riaz Mustafa, Muhammad Riaz, Muhammad Aziz ur Rahman, Waseem Abbas

“…Background and Aim: Soybean meal (SBM) is the primary protein source in broiler diets; however, its high cost and import dependency necessitate alternative protein sources. …”
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Mechanisms underlying the wound healing and tissue regeneration properties of a novel gauze dressing impregnated with traditional herbal medicine (Ya-Samarn-Phlae) in type 2 diabet... by Sineenart Sanpinit, Acharaporn Issuriya, Oraphan Sakulkeo, Palika Wetchakul, Surasak Limsuwan, Pinanong Na-Phatthalung, Siriwan Kantisin, Jian Tang, Sasitorn Chusri

“…This discovery reveals, for the first time, the underlying mechanisms of action of this traditional formulation, highlighting its potential as a cost-effective alternative for managing chronic wounds in resource-limited settings.…”
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Photocatalytic and Photo-Fenton-like Degradation of Cationic Dyes Using SnFe₂O₄/g-C₃N₄ Under LED Irradiation: Optimization by RSM-BBD an... by Yassine Elkahoui, Fatima-Zahra Abahdou, Majda Ben Ali, Said Alahiane, Mohamed Elhabacha, Youssef Boutarba, Souad El Hajjaji

“…These two components are particularly attractive due to their low cost and ease of fabrication. Various characterization techniques, including XRD, FTIR, SEM, and TEM, were used to confirm the successful integration of SnFe₂O₄ and g-C₃N₄ phases in the synthesized catalysts. …”
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