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64761
Developing a Randomised Efficacy PREcision medicine Platform trial design for Cavernomas: the CARE PREP study
Published 2025-03-01“…Objectives (1) Consolidate and initiate international collaborations between cerebral cavernous malformations researchers, cerebral cavernous malformations patient and public involvement groups, cerebral cavernous malformations research networks, and commercial partners; (2) Finalise a protocol for an efficient, international platform trial of multiple drugs using precision medicine (sporadic vs. familial cerebral cavernous malformations) that is both feasible and acceptable to patients and regulators; (3) Estimate the research, support and treatment costs of the platform trial and apply to the National Institute for Health and Care Research Efficacy and Mechanism Evaluation Programme. …”
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64762
Re-use of Building Products in the Netherlands
Published 2019-01-01“…Economic In the economic context, direct costs involved in the process of reusing including transportation, storage, and workforce to deconstruct (associated with technology), as well as costs associated with processes to recondition used products for retail are critical parts of the economic equation. …”
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64763
Predicting the Likelihood of Operational Risk Occurrence in the Banking Industry Using Machine Learning Algorithms
Published 2025-12-01“…These results have the potential to transform operational risk management in banks, leading to significant reductions in associated costs and losses.A key insight from this study is that leveraging large and diverse datasets can substantially enhance prediction accuracy. …”
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64764
Introduction
Published 2019-07-01“…Policy makers who promoted this formalisation assumed that interactive regional-design processes can, when employed at an early stage of implementation processes, explicate interdependencies among planning issues at different scales, facilitate discussions on these and in this way help to avoid conflict, delay and costs at later stages. In 2012, regional-design practice became associated with the set up top sector policy, a national policy aimed at an enhancement of internationally operating economic sectors (Ministeries van I&M et al., 2012). …”
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64765
La recerca de la igualtat a través de les polítiques educatives: abast i límits
Published 2007-01-01“…While such reforms are more costly and politically more difficult than many which have been implemented in the last twenty years, they still represent the best opportunity for education to encourage social and economic equality.…”
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64766
Mixed Land use Pattern in Deteriorated and Inefficient Neighborhoods of Region Eighteen of Tehran and its Role in Sustainable Neighborhood Regeneration
Published 2021-02-01“…The 18th Region of Tehran, as a part of such tissues of the country, is not exception to these problems and attention to efficient planning for their reconstruction can, while creating value, stimulate the process of tissue regeneration and solve problems within They will also meet part of the future development needs of Tehran and, as a result, prevent the growth of the outskirts of the city, whose infrastructure requires high costs. 2-Materials and Methods In the first step, information on the current status of the area and, deteriorated and inefficient urban areas is extracted from the basic maps of the detailed plan and land use of the area and field harvesting, by GIS software. …”
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64767
Human–wildlife interactions
Published 2025-02-01“…Other authors also mentioned the importance of planning interventions that optimize the participation of experts, policy makers, and affected communities and include the explicit, systematic, and participatory evaluation of the costs and benefits of alternative interventions (Treves et al., 2009). …”
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64768
The Effects of COVID-19 on Financial Distress and Tax Avoidance
Published 2025-03-01“…When considering tax avoidance, managers should weigh the benefits, such as reduced tax liabilities and increased cash flow, against potential costs, including audit expenses, penalties, and reputational damage that may arise.…”
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64769
Development of a Correlation Model of Adherence to Sports With the Mental Health of Students Participating in Sports Leisure Time
Published 2025-03-01“…Therefore, investing in it will reduce costs in the health sector and anti-corruption centers and reduce the level of individual and social anomalies (Bakr, Al-Ansari, and Karuni, 2017). 2. …”
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64770
Structural Explanation of Urban Tourism Development Challenges in Chaharmahal and Bakhtiari Cities
Published 2025-03-01“…Key challenges include inadequate and unsustainable infrastructure planning, limited advertising resources, high costs of accommodation and welfare, a shortage of experienced tour guides, overlapping organizational roles, and unclear responsibilities. …”
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64771
How do individuals with mental health disorder and spinal cord injury gain access to participate in voluntary sport groups in Switzerland?
Published 2025-01-01“…Moreover, the location of the VSGs and for some, the costs were relevant to athletes’ gaining access to VSGs. …”
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64772
Proposing a template for selecting the coordinates of laboratory standards for executive management of the country.
Published 2025-02-01“…This book emphasizes small-scale experiments conducted to collect feedback and reduce the costs of failure, and compares the similarities and differences of these laboratories globally with the aim of designing methods to inform policymakers. …”
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64773
The learning process of physical education lessons in education through virtual education
Published 2024-09-01“…More free internet volume to be given to students and teachers for holding educational classes in order to financially save part of the costs of virtual classes.…”
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64774
The Strategy of Young Citizens in the Field of Unanswered Demands: A Qualitative Study in Yazd City
Published 2024-03-01“…Conversely, ignoring citizens' demands can lead to disruptions in the citizenship process, destructive actions by citizens, and unnecessary social costs, ultimately perpetuating underdevelopment. …”
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64775
Explaining and Analyzing the Effect of Brand Value Components on Medical Tourism Development: A Case Study of Ahvaz Metropolis
Published 2025-06-01“…Many countries are increasingly focused on medical tourism due to its low operational costs and high revenue potential, prompting numerous developing nations to implement ambitious plans for industry expansion. …”
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64776
Experimental study on tensile performance of horizontal joint bolted connections in fully assembled modular construction reinforced concrete
Published 2025-01-01“…ObjectiveConcrete modular buildings have the advantages of superior structural integrity, high living comfort, and low construction and maintenance costs. In concrete module structures, the connections between modules critically determine the overall structural performance. …”
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64777
Evaluating the level of digitalization of the innovation process with artificial intelligence approach in the digital transformation of knowledge-based companies
Published 2025-02-01“…Moving in this direction reduces financial, time and human costs. The relevance of innovation to ensure the competitiveness of companies has been confirmed among researchers and professionals (Schiuma, 2012). …”
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64778
Effects of different types of fruit bags on the quality of Xiahui 10 peaches
Published 2025-03-01“…Although additional labor and costs are incurred, fruit bagging remains as an important technical measure to ensure quality and commercial production against high temperatures and humidity in summer, frequent pest and disease outbreaks, poor coloration and low commercial quality in the middle and lower reaches of the Yangtze River region. …”
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64779
Identifying Factors Affecting Self-Development of Iranian TV School Teachers: Report of A Qualitative Study
Published 2025-03-01“…Introduction One of the most common and costly organizational activities is human resource development, which includes the development of new skills, the improvement of existing skills, and behaviors and methods that affect employees (Vanhala & Ahteela, 2011). …”
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64780
Spatial Analysis of the Concentration of Knowledge-Based Firms in Iran
Published 2024-12-01“…Moreover, in regions where companies, industries, and populations are concentrated, negative externalities can arise, including congestion costs, pollution, high land rents, and disruptions to essential services, such as healthcare, education, and urban infrastructure. …”
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