Environmental Impact of Reducing Chemical Fertilizer Subsidies (Agricultural Crops in Zarandieh, Markazi Province) by S.M.J. Esfahani, E. Barikani

“…To model and analyze the data, positive mathematical programming with the cost function approach was used. Excel and GAMS software has been used to run the models. …”
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DPImpute: A Genotype Imputation Framework for Ultra‐Low Coverage Whole‐Genome Sequencing and its Application in Genomic Selection by Weigang Zheng, Wenlong Ma, Zhilong Chen, Chao Wang, Tao Sun, Wenjun Dong, Wenjing Zhang, Song Zhang, Zhonglin Tang, Kui Li, Yunxiang Zhao, Yuwen Liu

“…In summary, DPImpute can significantly expedite breeding programs through precise and cost‐effective genotyping and serve as a valuable tool for diverse population genotyping, encompassing both human and animal studies.…”
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Deep Learning and fMRI-Based Pipeline for Optimization of Deep Brain Stimulation During Parkinson’s Disease Treatment: Toward Rapid Semi-Automated Stimulation Optimization by Jianwei Qiu, Afis Ajala, John Karigiannis, Jurgen Germann, Brendan Santyr, Aaron Loh, Luca Marinelli, Thomas Foo, Radhika Madhavan, Desmond Yeo, Alexandre Boutet, Andres Lozano

“…However, the post-operative optimization (aimed at maximizing patient clinical benefits and minimizing adverse effects) of all possible DBS parameter settings using the standard-of-care clinical protocol requires numerous clinical visits, which substantially increases the time to optimization per patient (TPP), patient cost burden and limit the number of patients who can undergo DBS treatment. …”
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Quantitative MODS-Wayne assay for rapid detection of pyrazinamide resistance in Mycobacterium tuberculosis from sputum samples by Emily Toscano-Guerra, Roberto Alcántara, Katherine Lozano Untiveros, Robert Gilman, Louis Grandjean, Mirko Zimic, Patricia Sheen

“…This approach offers a direct and cost-effective solution representing a significant advancement in TB diagnostics, particularly benefiting resource-limited laboratories, primarily in developing regions. …”
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Removable brace as a viable alternative to cast immobilization for ankle fractures—a meta-analysis of randomized controlled trials by Xi Li, Xi Li, Xi Li, Kaiwen Yi, Kaiwen Yi, Shiqi Li, Shiqi Li, Na Liu, Lemei Zhu, Lemei Zhu, Lemei Zhu

“…Functional scores, complications, and time to return to work (RTW) were analyzed to assess the efficacy, safety, and cost of the two groups.ResultsWe included 11 RCTs with a total sample size of 1,472 participants. …”
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A randomized phase II/III trial of rosuvastatin with neoadjuvant chemo-radiation in patients with locally advanced rectal cancer by Prachi S. Patil, Avanish Saklani, Naveena A. N. Kumar, Ashwin De’Souza, Rahul Krishnatry, Snehal Khanvilkar, Mufaddal Kazi, Reena Engineer, Vikas Ostwal, Anant Ramaswamy, Munita Bal, Priya Ranganathan, Ekta Gupta, Ekta Gupta, Sanjeev Galande, Sanjeev Galande

“…The pathological response rate, tumor regression grade (TRG), and post-surgical complications will be recorded.ConclusionThe addition of rosuvastatin to NACTRT may improve the oncological outcomes by increasing the likelihood of pCR in patients with locally advanced rectal cancer undergoing NACTRT. This would be a low-cost, low-risk intervention that could potentially lead to the refinement of strategies, such as “watch and wait”, in a select subgroup of patients.Clinical trial registrationClinical Trials Registry of India, identifier CTRI/2018/11/016459.…”
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Health Outcomes and Resource Consumption Analysis of Radioembolization with Y90 Glass Microspheres (TARE-Y90) Versus Transarterial Chemoembolization with Irinotecan (DEBIRI) in Pat... by Juan José Ciampi-Dopazo, Gonzalo Ruiz Villaverde, Juan José Espejo, Raúl García Marcos, Daniel Pérez Enguix, Serena Pisoni, José J. Martínez-Rodrigo, Pablo Navarro Vergara, Pedro Pardo Moreno, Antonio Rodríguez-Fernández

“…<b>Background</b>: The present study aims to investigate the superiority of TARE-Y90 in the treatment of liver metastases from colorectal cancer in comparison to DEBIRI and perform a parallel resource consumption study to demonstrate a possible favorable cost-effectiveness balance. <b>Methods</b>: The number of subjects included in this study was 46 for TARE-Y90 and 56 in the DEBIRI group. …”
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Method and application of coal-based solid waste filling in multi-layer three-dimensional space of coal mining by Ke YANG, Xiang YU, Xiang HE, Xinyuan ZHAO, Juejing FANG, Zhen WEI, Shuxin HE

“…The multi-layer three-dimensional space coal-based solid waste filling method has innovated the new mode of large-scale disposal of coal-based solid waste in underground coal mines, improved the green filling mining technology system, and realized the coordinated control of the whole space of coal mining overburden rock and the leap of solid waste recycling technology, which can promote the fundamental transformation of coal enterprises from “environmental cost type” to “ecological value-added type”.…”
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Development of Deep-Sea Floating Wind Power Technology by Da Li, Tao Sun, Cong Yi, Wei Gao, Shuzhao Li, Baicheng Lyu, Hui Li, Yuming Zhang, Zhuolantai Bai, Junrong Wang, Huajun Li

“…Advancing the deep-sea floating wind power technology is an effective pathway to reducing costs and enhancing efficiency in offshore wind power development, driving structural reforms in the energy system, and achieving the carbon peaking and carbon neutralization vision. …”
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Current status and influencing factors of quality of life in patients with coronary heart disease and angina pectoris (冠心病心绞痛住院患者生活质量现状及影响因素分析)... by SONG Yingchanxi (宋莹婵茜), YU Linlin (余琳琳), ZHENG Tairong (郑太蓉), ZENG Min (曾敏), SU Shuili (苏水利)

“…Results The gender, age, Traditional Chinese Medicine syndrome score, angina symptom scoring scale were negatively associated with SAQ score for physical limitation. The age, total cost of hospitalization, pulse condition, and angina symptom scoring scale were negatively associated with SAQ score for anginal frequency. …”
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Improving mechanical properties of maraging steel by optimizing laser power in hybrid laser-arc directed energy deposition by Jikang Fan, Pengfei Gao, Baihao Cai, Gaige Chang, Mengwei Duan, Wei Zhang, Xiaoyong Zhang, Yong Peng, Kehong Wang

“…Introducing a laser as a preheating source in the Arc-based Directed Energy Deposition (DED-Arc) for the self-developed, low-cost, Co-free maraging steel welding wire, utilizing the synergistic effect between the laser and the arc, to explore its potential in optimizing material properties. …”
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Constructing Long and Stable Ag‐Al2O3 Core–Shell Nanowires for Humidity Sensing and Triboelectric Energy Generation by Jiajun Fan, Tao Wan, Yilin He, Chao Liu, Tingting Mei, Yu‐Chieh Kuo, Ziheng Feng, Peiyuan Guan, Chun‐Ho Lin, Mengyao Li, Lin Fu, Mengdie Tao, Tongxi Lin, Zhaojun Han, Jianbo Tang, Yeqing Xu, Caiyun Wang, Jin Zhang, Rakesh Joshi, Dewei Chu

“…This work provides a convenient, scalable, and cost‐effective solution that offers great potential for designing robust, transparent electrodes for next‐generation flexible electronics.…”
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Performance and hypothetical clinical impact of an mNGS-based machine learning model for antimicrobial susceptibility prediction of five ESKAPEE bacteria by Yaoguang Li, Sizhen Liu, Peng Han, Jun Lei, Huifen Wang, Weiwei Zhu, Zihui Dong, Yize Zhang, Zhi Jiang, Beiwen Zheng, Guanhua Rao, Zujiang Yu, Ang Li

“…Furthermore, mNGS-based AST can be integrated with clinical mNGS to maximize the utility of short-read data without substantial cost increases. This study demonstrates the potential of mNGS-based AST for precise, individualized antibacterial selection and highlights its broader applicability in enhancing clinical antimicrobial use for various infections.…”
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Hematological ratios and cytokine profiles in heterozygous beta-thalassemia by Ana Carolina Marques Ciceri, Laura Eduarda de Oliveira, Ana Luísa Richter, José Antonio Mainardi de Carvalho, Maylla Rodrigues Lucena, Guilherme Wataru Gomes, Maria Stella Figueiredo, Magnun Nueldo Nunes dos Santos, Vera Lúcia Nascimento Blaia-D'Avila, Rodolfo Delfini Cançado, Elvira Maria Guerra-Shinohara, Clóvis Paniz

“…These ratios, therefore are potentially cost-effective and easily applicable markers for monitoring patients with the β-thalassemia trait.…”
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Effect of seed priming and foliar application of organic liquid manure on germination, growth, yield and quality of late-sown wheat by Okram Ricky Devi, Omvati Verma, Bibek Laishram, S. Anbarasan, Abhijit Debnath, Narinder Panotra, Priyanka Elumle, Sunita T. Pandey, R. Ajaykumar, Samreen

“…From the current research, it can be concluded that HK is a successful and cost-efficient method that may be utilized to increase crop production under late-sown conditions.…”
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Maternal plasma cell-free RNA as a predictive test for fetal lung maturation by Sean W. D. Carter, Kay Yi Michelle Seah, Si En Poh, Winston Koh, Haruo Usuda, Erin L. Johnson, Yusaku Kumagai, Tsukasa Takahashi, Lara J. Monteiro, Reyna Peñailillo, Gino Nardocci, Hannah R. S. Watson, Masatoshi Saito, Mahesh A. Choolani, Sebastián E. Illanes, Matthew W. Kemp

“…Conclusions Further development of this technology may provide a rapid, minimally invasive, and cost-effective clinical tool to optimize patient selection for initial and repeat courses of antenatal steroids, along with insights into the molecular mechanisms underlying fetal lung development. …”
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A Promising Approach to Ultra‐Flexible 1 Ah Lithium–Sulfur Batteries Using Oxygen‐Functionalized Single‐Walled Carbon Nanotubes by Junyoung Heo, Jeong‐Won Hong, Ha Won Gu, Junghwan Sung, Dong‐Hee Kim, Jung Hoon Kim, Sung Kang, You‐Jin Lee, Hye Young Choi, Doohun Kim, Kang‐Jun Baeg, Joong Tark Han, Jun‐Woo Park

“…These batteries are also cost‐effective, abundant, and environment‐friendly. …”
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Inorganic constituents in cassava derivatives: Total concentration, dietary intake and bioaccessibility by Leilane R. Santos, Filipe B. Santana, Hilária F.A. Silveira, Wellington C. de Carvalho, Laís A. Souza, Rennan Geovanny O. Araujo, Maria Graças A. Korn, Daniele Cristina M.B. Santos

“…Conclusion: This study makes a significant contribution by proposing a simple and low-cost procedure for evaluating the mineral composition of cassava samples, as well as bioaccessibility estimation of Mn and Mg, providing new nutritional information of interest to public health.…”
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Choosing Healthy Eating for Infant Health (CHErIsH) study: protocol for a feasibility study by Catherine Hayes, Elaine Toomey, Caragh Flannery, Patricia M Kearney, Molly Byrne, Catherine Stanton, Colette Kelly, Karen Matvienko-Sikar, Michelle Queally, Kate O Neill, Ted G Dinan, Edel Doherty, Janas M Harrington, Caroline Heary, Marita Hennessy, Sheena M Mc Hugh, Jenny McSharry, Tony Heffernan

“…Data from electronic delivery prompts will also be collected to examine implementation of the intervention. A cost–outcome description will be conducted to measure costs of the intervention and the implementation strategy.Ethics and dissemination This study received approval from the Clinical Research Ethics Committee of the Cork Teaching Hospitals. …”
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Anti-cancer drug sensitivity testing and preclinical evaluation of the anti-cancer potential of WEE1 inhibitor in triple-negative breast cancer patient-derived organoids and xenogr... by Seungyeon Ryu, Hoe Suk Kim, Sangeun Lee, So-Hyun Yoon, Moonjou Baek, A Young Park, Han-Byoel Lee, Ga Yeon Kim, Kyung Hyeun Park, Ji-Jung Jung, Yireh Han, Dong Woo Lee, Bosung Ku, Wonshik Han

“…PDOs and PDXOs represent cost- and time-effective surrogates for predicting prioritized personalized therapy.…”
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