Ranibizumab versus bevacizumab for ophthalmic diseases related to neovascularisation: a meta-analysis of randomised controlled trials. by Bin Wu, Haixiang Wu, Xiaoyan Liu, Houwen Lin, Jin Li

“…The use of bevacizumab was associated with an increased risk of developing serious systemic events. Weighing the costs and health outcomes is necessary when selecting between bevacizumab and ranibizumab for ophthalmic diseases. …”
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Optimizing Transport Logistics under Uncertainty with Simheuristics: Concepts, Review and Trends by Juliana Castaneda, Elnaz Ghorbani, Majsa Ammouriova, Javier Panadero, Angel A. Juan

“…Hence, it must be combined with optimization methods when our goal is to: (i) minimize operating costs while guaranteeing a given quality of service; or (ii) maximize system performance using limited resources. …”
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Os protocolos das modernizações urbanas na história recente da cidade do Recife. // The protocols of urban modernization in the recent history of the city of Recife. by Luís Manuel Nascimento

“…Modernization which was designed by the activities of constituted public authority, associated with capital, coming from new opportunities allied with the wealthier classes interested in gainning money quickly, burdened the lower classes with the costs of this modernism, subsequently, expressed in literary narratives related to the period. …”
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Aspects of design and calculation of a railway track intended for dedicated passenger lines by D. V. Ovchinnikov, K. A. Kul’gin

“…The article considers issues of application of dedicated passenger lines for intertown and interregional transportation on the railways of the Russian Federation, which in the future will accelerate passenger traffic due to changes in transportation technology, increase the carrying and throughput capacity of railways, reduce construction costs and current maintenance, and optimize the need for infrastructure development. …”
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Quality of care of patients with type 2 diabetes mellitus at a public sector district hospital by Kelly J. Fredericks, Mergan Naidoo

“…Background: Globally, diabetes mellitus (DM) remains one of the leading causes of mortality, with approximately 2 million deaths in 2019, the condition also contributes significantly to adverse health conditions and costs. The study aimed to describe the quality of care (QOC) rendered to patients with type 2 DM (T2DM) seeking care at Wentworth Hospital (WWH), a district hospital in KwaZulu-Natal province, South Africa. …”
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Accelerated Bayesian optimization for CNN+LSTM learning rate tuning via precomputed Gaussian process subspaces in soil analysis by Xiaolong Chen, Hongfeng Zhang, Cora Un In Wong, Zhengchun Song

“…This work bridges the gap between computational efficiency and probabilistic robustness, with broader implications for automated machine learning in geoscientific applications.MethodThe key innovation lies in a subspace-accelerated GP surrogate model that precomputes low-rank approximations of covariance matrices offline, thereby decoupling the costly hyperparameter tuning from the online acquisition function evaluations. …”
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Trends in the application of chondroitinase ABC in injured spinal cord repair by Zhongqing Ji, Jiangfeng Zhu, Jinming Liu, Bin Wei, Yixin Shen, Yanan Hu

“…Moreover, the extensive and long-term medical care required for spinal cord injury significantly increases healthcare costs and resources, adding a substantial burden to the healthcare system and patients’ families. …”
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STRESS-DEFORMED STATE OF A STRUT-FRAMED CRANE GIRDER by Kh. M. Muselemov, O. M. Ustarkhanov, A. K. Yusupov

“…The dependence of the moments and transverse forces on the dimensionless parameter k was found, the corresponding graphs were plotted and the metal costs for the girders were calculated. The minimum values of the moments and transverse forces are established to take place when the dimensionless parameter k values are close to zero. …”
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Analysis and Design of a Multiple-Driver Power Supply Based on a High-Frequency AC Bus by Qingqing He, Zhaoyang Tang, Wenzhe Zhao, Keliang Zhou

“…Meanwhile, achieving precise current sharing among channels without incurring high costs and system complexity is a significant challenge. …”
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Malreduction of Syndesmosis and Outcomes Following Trans-Syndesmotic Screw vs Suture Button Fixation Under Direct Visualization and Reduction Technique: A Prospective Randomized Co... by Chamnanni Rungprai MD, Yantarat Sripanich MD, Suthavee Pangkanon MD, Methasit Suksintharanon MD

“…While suture button fixation has demonstrated efficacy in reducing malreduction rates compared to trans-syndesmotic screw fixation, it incurs higher implant costs. However, the introduction of a direct visualization and reduction technique offers the possibility to mitigate the difference. …”
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The Potential of Artificial Intelligence in Pharmaceutical Innovation: From Drug Discovery to Clinical Trials by Vera Malheiro, Beatriz Santos, Ana Figueiras, Filipa Mascarenhas-Melo

“…The algorithms developed can predict the efficacy, toxicity, and possible adverse effects of new drugs, optimize the steps involved in clinical trials, reduce associated time and costs, and facilitate the implementation of innovative drugs in the market, making it easier to develop precise therapies tailored to the individual genetic profile of patients. …”
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A bioenergetic approach favors the preservation and protection of prey, not cooking, as the drivers of early fire by Miki Ben-Dor, Ran Barkai

“…., ~1,200 ca/h for meat), insufficient to offset fire maintenance costs, unlike preservation and protection.DiscussionThe substantial energetic disparity supports hunting as a dominant subsistence strategy, with fire enhancing efficiency by preserving meat and deterring predators. …”
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Prediction of Type 2 Diabetes Mellitus using a Logistic Regression Model by Olivia Altamirano Guerrero, Ronelsys Martínez Martínez, Jhonny Alejandro Rodríguez Gutiérrez

“…Detecting the disease at an early stage helps reduce medical costs and the risk of patients having more complicated health problems. …”
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A Study of Multi-distributed Resource Equalization Allocation for Virtual Power Plants Based on Genetic-heuristic Algorithm by Haifeng Li, Tao Jin, Xian Xu, Lin Shi

“…By establishing models of wind, solar, storage, and controllable load characteristics, an optimization model is constructed with objectives of resource allocation balance and minimization of call costs, subject to constraints such as power balance. …”
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Multimodal Particulate Matter Prediction: Enabling Scalable and High-Precision Air Quality Monitoring Using Mobile Devices and Deep Learning Models by Hirokazu Madokoro, Stephanie Nix

“…We consider that this research connects high-performance computing with energy-efficient hardware solutions, creating a practical framework for distributed environmental monitoring that reduces reliance on costly centralized monitoring systems. Our findings indicate that transformer-based multimodal models present a promising approach for mobile sensing applications, with opportunities for further improvement through seasonal data expansion and architectural refinements.…”
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Benchmarking of Anomaly Detection Methods for Industry 4.0: Evaluation, Ranking, and Practical Recommendations by Aurélie Cools, Mohammed Amin Belarbi, Sidi Ahmed Mahmoudi

“…Quality control and predictive maintenance are two essential pillars of Industry 4.0, aiming to optimize production, reduce operational costs, and enhance system reliability. Real-time visual inspection ensures early detection of manufacturing defects, assembly errors, or texture inconsistencies, preventing defective products from reaching customers. …”
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Machine Learning Forecasting of Commercial Buildings’ Energy Consumption Using Euclidian Distance Matrices by Connor Scott, Alhussein Albarbar

“…However, such methods typically rely on extensive historical data collected via costly sensor installations—resources that many buildings lack. …”
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ECONOMIC INNOVATIONS OF THE PAST ERA by A. Chernikov

“…The functional and price analysis, as a method of reducing the costs, was practically implemented in 1970s.Then in the late 1970s and during the early 1980s the experiments on the implementation the system of planning and accounting the national economic effect in production capacity dynamics under the influence of scientific and technical progress, including the concept of indicators’ balanced system were held.The collective forms of labour organization and incentive in large subdivisions were firstly applied as early as 1930s in the industrialization period and were developed during the early 1990s. …”
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<p><strong>Deep-learning techniques for symptoms' detection of <em>Aculops lycopersici</em></strong> <strong>(Acari: Eriophyidae) and <em>Tuta absoluta</em></strong> (<strong>Lepid... by Alireza Shabani Nezhad, Maryam Aleosfoor

“…Traditional methods of identifying and counting pests in plants require continuous monitoring, which is very costly and time-consuming in large farms, and involves uncontrollable human errors. …”
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About Possibility of Remote Diagnostics of the Respiratory System by Auscultation by E. G. Zaitseva, M. V. Chernetsky, N. A. Shevel

“…The organizational tasks that need to be solved for the implementation of diagnostics are formulated.Use of the method of remote diagnostics of the respiratory system, providing the ability to determine points of auscultation without the direct presence of a diagnostic specialist and the module will allow increasing efficiency of treatment of pulmonary diseases reduce infection risks and economic costs.…”
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