Evaluating a Community Health Worker Training Program for Medication Adherence Support by Richard Segal, RPh, PhD, Michelle L. Zeigler, PharmD, PhD, BCACP, Jordan L. Wallace, PharmD, BCOP, Teresa E. Roane, PharmD, MBA, BCACP, Lorraine Mobley, RPh, CPh, BCGP, Folakemi T. Odedina, PhD

“…Introduction: Medication nonadherence significantly contributes to poor health outcomes and increased healthcare costs, particularly in chronic diseases like hypertension. …”
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A Study on the Pore and Strength Characteristics of an Eco-Friendly Sprayed Ultra High Performance Concrete with Manufactured Sand by Zhonghao Wang, Xianjun Tan, Jingqiang Yuan, Chongge Wang, Yubiao Liu

“…Furthermore, the sprayed UHPC incorporating manufactured sand derived from tunnel slag not only maintains a 28-day compressive strength of 110.9 MPa but also reduces material costs and enhances sustainability. Field tests validate its low rebound rate (<5%) and rapid strength development (achieving a compressive strength of 30 MPa within 1 day), confirming its adaptability to complex geological conditions such as high-stress zones, thereby providing a novel method for support in complex geological conditions.…”
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Innovative coastal defence using rock bag revetments: preliminary physical modelling by Henry Moss, Mohammad Heidarzadeh, Ramtin Sabeti

“…However, these revetments are costly and have a high carbon footprint due to their large size and the long transport distances required. …”
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Development and evaluation of LLM-based suicide intervention chatbot by Xueting Cui, Xueting Cui, Yun Gu, Yun Gu, Hui Fang, Tingshao Zhu, Tingshao Zhu

“…Traditional suicide intervention methods are hampered by shortages of qualified practitioners, variability in clinical competence, and high service costs. This study leverages Large Language Models (LLMs) to develop an effective suicide intervention chatbot, which provides early, large-scale, rapid self-help interventions.MethodsFirst, according to existing psychological crisis intervention methods, we fine-tuned ChatGPT-4 via prompt engineering to develop a chatbot that promptly responds to the needs of individuals experiencing suicidal ideation. …”
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The Predictive Value of Serum Total IgE for Antihistamine Treatment Outcomes in Chinese Patients with Chronic Spontaneous Urticaria by Yingyi Li, Rui Peng, Jingwen Xue, Yi Zhao

“…Predictors of treatment response to second-generation H1-antihistamines could help optimize disease management and minimize unnecessary healthcare costs. In this retrospective cohort study of 99 Chinese chronic spontaneous urticaria patients, higher log-transformed serum total IgE levels were significantly associated with poor response to standard-dose antihistamines (aOR = 2.09, 95% CI: 1.29–3.38, p = 0.003). …”
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A Model for Detecting <i>Xanthomonas campestris</i> Using Machine Learning Techniques Enhanced by Optimization Algorithms by Daniel-David Leal-Lara, Julio Barón-Velandia, Lina-María Molina-Parra, Ana-Carolina Cabrera-Blandón

“…Its rapid spread across large crop areas results in economic losses, compromises agricultural productivity, increases management costs, and threatens food security, especially in small-scale agricultural systems. …”
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Engineering Yarrowia lipolytica for high-level β-elemene production via combinatorial metabolic strategies by Mingyu Dai, Qingyi Cao, Shuanglong Jia, Jiang Chen, Hui-Ying Xu, Bang-Ce Ye, Wei-Bing Liu, Ying Zhou

“…Currently, its commercial production relies heavily on plant extraction, a process associated with high costs and environmental burdens, limiting industrial scalability. …”
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GraphEPN: A Deep Learning Framework for B-Cell Epitope Prediction Leveraging Graph Neural Networks by Feng Wang, Xiangwei Dai, Liyan Shen, Shan Chang

“…Traditional experimental techniques are hindered by high costs, time consumption, and limited scalability, making them unsuitable for large-scale applications. …”
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Enhancing Youbike Redistribution System: A Study on Station Recommendation Using a Genetic Algorithm by Yang-Chou Juan, Yi-Chung Chen, Wei-Ting Chen, Chieh Yang, Chia-Tzu Liu, Yi-Ci Hou, Yi-Hsuan Tsai

“…Simulations demonstrated that the proposed system meets user needs, enhances operational efficiency, and significantly reduces manual redistribution costs. Our methods have practical applicability for YouBike managers, indicating that user compliance with recommendations can offset the need for manual redistribution and support the current policy of recommending stations within 600 m of the user’s destination.…”
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Development and Performance Evaluation of a Gel-Based Plugging System for Complex Fractured Formations Using Acrylic Resin Particles by Lei Yao, Xiaohu Quan, Jihe Ma, Ge Wang, Qi Feng, Hui Jin, Jun Yang

“…The issue of fluid loss in fractured formations presents a significant challenge in petroleum engineering, often leading to increased operational costs and construction risks. To address the limitations of traditional lost circulation materials (LCMs) in oil reservoirs with different fracture sizes, this study developed an acrylic resin gel particle with excellent thermal stability (thermal decomposition temperature up to 314 °C) and compatibility. …”
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Building the neighborhood for the trees: Illuminating win–wins for housing densification and nature by Max R. Lambert, Simone Des Roches, Daniel A. Auerbach, Braeden Van Deynze, Syler Behrens, Robin Hale, Kenneth B. Pierce

“…Abstract Housing deficits are pervasive because of multiple factors including insufficient new construction, rising costs, restrictive zoning, and income inequality. …”
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TWO-YEAR MORTALITY PROFILE IN ELDERLY WITH FRAILTY : Observational Descriptive Study in Elderly Health Community in Surabaya, Indonesia by Ummi Ziyadatul Faizah, Novira Widajanti, Jusri Ichwani

“…Frailty raises the risk of death and health care costs, as well as functional disability, hospitalization, and fall risk. …”
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Spending, utilization, and price trends for anti-obesity medications in U.S. Medicaid programs: an empirical analysis from 1999 to 2023 by Abdulrahman A. Alsuhibani, Marwan A. Alrasheed, Ibrahim S. Alhomoud, Saud Alsahali, Ziyad S. Almalki, Jeff Jianfei Guo

“…The largest share of the market growth in 2023 was driven by these medications.ConclusionThe significant increase in AOM utilization and spending highlights the growing burden of obesity on Medicaid, emphasizing the need for policy measures to manage rising costs and ensure equitable access to treatment.…”
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Monitoring Ulva prolifera to prevent cooling water intake blockages at nuclear power plants using remote sensing by Haiting Wang, Xueqiang Zhu, Yanyan Cui, Hongtao Ai, Shuai Cai, Mengting Li, Jianying Wang

“…Remote sensing can support the provision of early warnings, enabling proactive management to control the spread of biohazards, reduce harvesting frequency, lower labor costs, and mitigate risks to cooling water intake systems.…”
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Artificial Intelligence for Drug Discovery Accelerating the Development of New Pharmaceuticals by Basri T. Syeda Jeelani, Kulkarni Adokshaja Krishnarao, K Renuka, B Yamini Supriya, R V Kavya, A Buckshumiyan

“…Thus, this approach will shorten drug development timelines, reduce healthcare costs, and improve quality of life for patients through more effective personalized treatment options. …”
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A lightweight remote sensing image detection model with feature aggregation diffusion network by Xiaohui Cheng, Xukun Wang, Yun Deng, Qiu Lu, Yanping Kang, Jian Tang, Yuanyuan Shi, Junyu Zhao

“…The central convolutional detection head combines detail-enhanced convolution and group normalization, reducing computational costs by 23.4 % while maintaining precision. A dilation-wise residual module further optimizes multi-scale feature extraction. …”
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The petrochemical historical bloc: Exposing the extent and depth of opposition to a high-ambition plastics treaty by Peter Dauvergne, Rob Ralston, Jennifer Clapp, Jack Taggart

“…This bloc is driving up plastics production, externalizing the costs of pollution, distorting scientific knowledge and lobbying to derail negotiations. …”
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Spike-RISC: Algorithm/ISA Co-Optimization for Efficient SNNs on RISC-V by Ipek Akdeniz, Sandy A. Wasif, Paul R. Genssler, Hussam Amrouch

“…However, their leaky-integrate and fire (LIF) neurons rely on complex floating-point equations, which are very costly in embedded systems. Further, many computations are unnecessary because SNNs are inherently sparse. …”
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Robot-Assisted Transcranial Magnetic Stimulation (Robo-TMS): A Review by Wenzhi Bai, Andrew Weightman, Rory J O'Connor, Zhengtao Ding, Mingming Zhang, Sheng Quan Xie, Zhenhong Li

“…Our findings suggest that broader clinical adoption of Robo-TMS is currently limited by unverified clinical applicability, high operational complexity, and substantial implementation costs. Emerging technologies&#x2014;including marker-less tracking, non-rigid registration, learning-based electric field (E-field) modelling, individualised magnetic resonance imaging (MRI) generation, robot-assisted multi-locus TMS (Robo-mTMS), and automated calibration and registration&#x2014;present promising pathways to address these challenges.…”
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Viral infections and immune modulation in bladder cancer: implications for immunotherapy by Lívia Bitencourt Pascoal, Mehrsa Jalalizadeh, Gabriela Barbosa, Andrea Nazare Monteiro Rangel da Silva, Maria Alice Freitas Queiroz, Ekaterina Laukhtina, Shahrokh F. Shariat, Alessandra Gambero, Leonardo O. Reis

“…A deeper understanding of viral-induced immune dysregulation may improve prognostic assessment, optimize treatment protocols, and reduce healthcare costs associated with bladder cancer. Future research should focus on targeted interventions to mitigate the immunosuppressive effects of chronic infections, ultimately improving patient outcomes in NMIBC management.…”
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