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25741
COVID-19 and a Tale of Three Drugs: To Repurpose, or Not to Repurpose–That Was the Question
Published 2025-06-01“…Repurposing of an already approved drug may accelerate the introduction of that drug into clinical use by circumventing early, including preclinical studies otherwise essential for a de novo drug and reducing development costs. Early in the pandemic three drugs were identified as repurposing candidates for the treatment of COVID-19: (i) hydroxychloroquine, an anti-malarial also used to treat rheumatoid arthritis and lupus; (ii) ivermectin, an antiparasitic approved for both human and veterinary use; (iii) remdesivir, an anti-viral originally developed to treat hepatitis C. …”
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25742
Improving Sewer Damage Inspection: Development of a Deep Learning Integration Concept for a Multi-Sensor System
Published 2024-12-01“…Advancements in artificial intelligence (AI) and computer vision offer significant potential to automate sewer inspections, improving reliability and reducing costs. However, the existing vision-based inspection robots fail to provide data quality sufficient for training reliable deep learning (DL) models. …”
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25743
A systematic review and meta-analysis on pharmacist-led interventions for the management of peptic ulcer disease.
Published 2025-01-01“…Pharmacist interventions have a significant impact on improving rational drug use, reducing costs and treatment duration, and enhancing appropriate medication use. …”
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25744
The Electric Riverboat Charging Station Location Problem
Published 2020-01-01“…In this case, we decide the location of the PVCSs and the size of the EB battery aiming to minimize the sum of the PVCS and the EB battery costs. In this problem, we include the nonlinear behavior of the charging function and the variation of the solar radiation. …”
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25745
FACTORS INFLUENCING INFORMATION AND COMMUNICATION TECHNOLOGY ADOPTION IN SMALL AND MEDIUM ENTERPRISES IN JIJEL, ALGERIA
Published 2025-03-01“…The adoption of ICT can provide small and medium enterprises (SMEs) with a competitive advantage by enhancing quality, reducing costs, and increasing information flow. This study aims to identify the factors that influence the adoption of various information and communication technologies in Small and Medium Enterprises (SMEs) located in Jijel province in Algeria. …”
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25746
Development of a Fault-Tolerant Permanent Magnet Synchronous Motor Using a Machine-Learning Algorithm for a Predictive Maintenance Elevator
Published 2025-05-01“…This necessitates advanced monitoring techniques to ensure safety, system reliability, and reduced maintenance costs. In this study, a fault-tolerant PMSM is designed and evaluated through 2D Finite Element Analysis (FEA), optimizing key electromagnetic parameters. …”
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25747
Research of selection seeds drying in dense layer
Published 2018-03-01“…When increase in moisture inconstant the stability of grain mass at storage decreases, there is a danger of emergence of heating, the overall performance of dryers and other processing equipment decreases, energy costs for seeds production rise. To eliminate this shortcoming located in a grain layer or grain stream the dried-up product should be mixed carefully for the best uniformity. …”
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25748
Opposition-based chaotic evolution for optimization
Published 2025-07-01“…Abstract Evolutionary computation algorithms are widely used for solving complex optimization problems, but their practical performance is often hindered by high computational costs and premature convergence. To address this challenge, we propose an opposition-based chaotic evolution (OBCE) algorithm that integrates opposition-based learning (OBL) into the chaotic evolution framework. …”
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25749
A new lattice-based partially blind signature with more complete proof
Published 2024-05-01“…In addition, the hash tree technology is used to reduce communication costs and improve interactive performance. In order to avoid the errors in the security proof of the previous scheme, our proof builds upon and extends the modular framework for blind signatures of Hauck et al. and the correctness, partial blindness, and one-more unforgeability of the scheme are proved in detail according to the properties of the linear hash function.…”
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25750
Immobilization of Palladium(II)acetate complex on dendrimer functionalized Cobalt ferrite nanoparticles as a nanocatalyst for Suzuki–Miyaura coupling and oxidation of sulfide
Published 2025-07-01“…This is important for sustainable chemistry, as it reduces waste and potentially lowers the costs.…”
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25751
A human‐robot collaboration method for uncertain surface scanning
Published 2025-06-01“…Moreover, it usually requires surface modelling with additional sensors, which might be time‐consuming and costly. A human‐robot collaboration‐based approach that allows a human user and a robot to assist each other in scanning uncertain surfaces with uniform properties, such as scanning human skin in ultrasound examination is proposed. …”
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25752
ҚАЗАҚСТАН РЕСПУБЛИКАСЫНДАҒЫ ТАМАҚ ӨНЕРКӘСІБІ КӘСІПОРЫНДАРЫНЫҢ ИННОВАЦИЯЛЫҚ ДАМУЫ: ПРОБЛЕМАЛАРЫ МЕН ПЕРСПЕКТИВАЛАРЫ...
Published 2019-03-01“…Introducing new products helps firms protect their margins, while investing in process innovation helps firms lower their costs.In this article, the authors identified the importance of innovation in ensuring the competitiveness of the country and economic development, as well as their special role in the food industry. …”
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25753
Learning Approach for Angle Estimation Based on Characteristics of Phase Drift
Published 2025-03-01“…Despite advancements, challenges such as signal fluctuations, multipath effects, and high infrastructure costs limit the accuracy and adoption of these systems. …”
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25754
Investigate the Effect of Strength and Endurance Training on the Severity of Depression and Patients' Working Memory Capacity
Published 2025-03-01“…It seems that resistance and aerobic training have a significant positive effect on improving the working memory capacity of depressed patients. which are universally applicable in the community and do not require huge costs, is effective in changing and improving the psychological problems of patients with depression. …”
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25755
Providing the spatial rigidity of a multi-story wood-based frame building
Published 2021-01-01“…With its help, it is possible to avoid an excess of spatial rigidity of the building and reduce the time and labor costs for selecting the location of rigid elements.…”
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25756
POSSIBILITIES OF INTEGRATED CONTROL OF ENERGY AND ENVIRONMENTAL CHARACTERISTICS OF BUILDING STRUCTURES AT THE RESEARCH BENCH
Published 2019-07-01“…It has been suggested and proved that the experience of joint use of the laws of nonequilibrium and phenomenological thermodynamics for research and modeling of nonequilibrium thermodynamic processes occurring in systems of various kinds, allows you to control their ecological state and increases the accuracy of forecasting costs and rational use of energy resources.…”
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25757
Entering new markets: nuclear industry challenges
Published 2021-07-01“…Such markets pay more for energy because of organization and transport costs and use of small machines, which are less efficient than grid generators. …”
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25758
Modeling growth, yield, irrigation water use and soil moisture dynamics of OPSIS-irrigated sugarcane
Published 2025-06-01“…Utilizing crop models to assess OPSIS could reduce the need for time-consuming and costly field trials. This study aimed to enhance the modeling capabilities of the Agricultural Production Systems Simulator (APSIM) to simulate the growth, yield, water use, and soil moisture dynamics of OPSIS-irrigated sugarcane (Saccharum officinarum L.). …”
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25759
Algorithm development for recognizing human emotions using a convolutional neural network based on audio data
Published 2022-12-01“…The proposed algorithm has a high accuracy of operation and does not require large computational costs.…”
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25760
Bitcoin and Main Altcoins: Causality and Trading Strategies
Published 2025-08-01“…The best Bitcoin trading strategy is based on the model which incorporates the information on all cryptocurrencies, exhibiting a cumulative return of 331% and an annualized Sharpe ratio of 94.59%, considering an enter/exit threshold of 0.25% and after 0.5% round-trip transaction costs. These results are statistically significant when compared with the buy-and-hold strategy, which renders a cumulative return of 121% and a Sharpe ratio of 64.74%. …”
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