Genetics Navigator: protocol for a mixed methods randomized controlled trial evaluating a digital platform to deliver genomic services in Canadian pediatric and adult populations by Trevor Jamieson, Kevin Thorpe, Francois Bernier, Melyssa Aronson, Marc Clausen, Rita Kodida, Emma Reble, June C Carroll, Jordan Lerner-Ellis, Yvonne Bombard, Matthew Osmond, Muhammad Mamdani, Ronald Cohn, Emily Seto, Hanna Faghfoury, Josh Silver, Maureen Smith, Lauren Chad, Jan M Friedman, Robin Z Hayeems, Michael Brudno, Gregory Costain, Quynh Pham, Anne-Marie Laberge, Christian Marshall, Cheryl Shuman, Rebekah Jobling, Irfan Dhalla, Serena Shastri-Estrada, Daniel Assamad, Stephanie Luca, Stacy Hewson, Eriskay Liston, Frank Rudzicz, Wendy Ungar, Guylaine D'Amours

“…A subset of participants will be interviewed to explore user experience; data will be analysed using interpretive description. A cost-effectiveness analysis will examine the incremental cost of the Navigator compared with usual care per unit reduction in distress or unit improvement in quality of life from public payer and societal perspectives.Ethics and dissemination This study was approved by Clinical Trials Ontario. …”
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Development and Validation of a Critical Thinking Questionnaire: A Case Study of the Lived Experience of Students from the University of Isfahan and Isfahan University of Medical S... by Esmaeil Kashef, Maghsod Farasatkhah, Vahid Ghasemi, Mozhgan Mohammadi Naeni

“…Additionally, mandatory and prescriptive curricula significantly limited the capacity for critical thinking. The factor of "cost-reward duality" illustrated the challenges and contradictions students encountered when exercising critical thinking. …”
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Integrative Approach to Teaching of the Circuit Design of Analog Electron Devices in the NI ELVIS Platform by Oleg V. Stukach, Arman B. Mirmanov

“…However, the shortage of laboratory equipment and assistants for maintenance and assistance in work, its high cost reduce the quality of laboratory work. On the other hand, modern education is increasingly using a network resource. …”
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Effects of Nutritional Status During Sexual Maturation and Resource Availability on the Resource Allocation of Females in Burying Beetles by Wenxia Wang, Guojun Zhou, Wei Zhang, Kai Tian, Lunguang Yao

“…Finally, our findings suggest that poor‐fed females did not suffer a future cost in offspring performance. Meanwhile, a large carcass allowed females to produce more and heavier offspring. …”
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Cellulosic-based microneedles for sensing heavy metals in fish samples by Houman Kholafazad, Mahdiyeh Pazhuhi, Mohammad Hasanzadeh, Nicolas H. Voelcker, Nasrin Shadju, Azadeh Nilghaz

“…However, some MN manufacturing methods involve complex procedures, costly equipment, and non-biocompatible materials. …”
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Swedish regional population-based organised prostate cancer testing: why, what and how? by Ola Bratt, Salma Tunå Butt, Charlotte Carlsson, Lisa Jelf-Eneqvist, Olof Gunnarsson, Alma Ihre, Thomas Jiborn, Anna Lantz, Heide Larsson, Helena Strömqvist, Johan Styrke, Nils-Erik Svedberg, Rebecka Arnsrud Godtman

“…Despite this, regional OPT was considered motivated to (1) improve cost-effectiveness compared with unorganised testing, (2) improve equity by giving every man in the target population a chance to make an informed choice, and (3) gain diagnostic and organisational knowledge. …”
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Comparative analysis of digital mammography and contrast-enhanced mammography in diagnosing suspicious breast calcifications: implications for surgical decision-making by Marwa Mohamed Taher Mohamed ElSayad, Maha Hussein Mohamed Helal, Omar Hussein Omar, Ahmed Gamal Eldeen Othman, Marwa Elsayed Abdelrahman Ibrahim

“…Contrast-Enhanced Mammography (CEM) incorporates pathological contrast-enhancement, leading to a more confident diagnosis, and offering a faster and more cost-effective tool than breast magnetic resonance imaging. …”
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Food Fortification and Nutrition Enhancement Strategies in the Agri-food Sector in Support of the Farm-To-Fork Initiative of the European Union by Mihaela MIHAI, Călina CIONT, Cristina MARCHIȘ, Ligia OLAR-POP, Oana Lelia POP

“…Interventions were assessed using criteria such as effectiveness, feasibility, sustainability, and cost-efficiency. Stakeholder engagement in these studies included consultations with farmers, food processors, policymakers, and consumer representatives motivated by results that reveal the combination of traditional and innovative techniques reduces nutrient loss by up to 30%, while improving micronutrient delivery efficiency by 25–40%. …”
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Fabrication of hydrogel mini-capsules as carrier systems [version 3; peer review: 1 approved, 4 approved with reservations] by Gaia Petrucci, Stefano Palagi, Elisa Roberti, Francesco Bianciardi

“…In this study, we present a cost-effective method for fabricating core-shell structures without the use of organic solvents, surfactants, or extreme pH conditions. …”
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Marker pen writing of perovskite solar modules by Yuhao Song, Miaosen Yao, Chen Dong, Sergey Dayneko, Gaogeng Wang, Dongyang Zhang, Yingying Deng, Junjie Tong, Qichao Wang, Gentian Yue, Yueyue Gao, Weifeng Zhang, Makhsud I. Saidaminov, Furui Tan

“…Abstract Solution-processed perovskite photovoltaics promise low-cost, lightweight, and wearable power sources. Processing techniques play a crucial role in this field. …”
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A Complete System for Automated Semantic–Geometric Mapping of Corrosion in Industrial Environments by Rui Pimentel de Figueiredo, Stefan Nordborg Eriksen, Ignacio Rodriguez, Simon Bøgh

“…., electrochemical testing) or based on costly equipment (e.g., ultrasonic sensors), our designed multi-modal vision-based system is low cost, portable, and semi-autonomous and allows the collection of large datasets by untrained personnel. …”
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Biochemical, Hematological and Clinical Profile of Dengue Patients in a Tertiary Care Centre by Ramsha Waseem, Hania Tariq, Abdul Rafey, Zain Nasir, Momina Hayat, Javed Iqbal

“…The platelet count proved to be a reliable, low-cost marker for early severity grading, complemented by the consistent presence of leukopenia. …”
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Minimally Invasive Alveolar Ridge Preservation Utilizing an In Situ Hardening β-Tricalcium Phosphate Bone Substitute: A Multicenter Case Series by Minas D. Leventis, Peter Fairbairn, Ashish Kakar, Angelos D. Leventis, Vasileios Margaritis, Walter Lückerath, Robert A. Horowitz, Bappanadu H. Rao, Annette Lindner, Heiner Nagursky

“…Ridge preservation measures, which include the filling of extraction sockets with bone substitutes, have been shown to reduce ridge resorption, while methods that do not require primary soft tissue closure minimize patient morbidity and decrease surgical time and cost. In a case series of 10 patients requiring single extraction, in situ hardening beta-tricalcium phosphate (β-TCP) granules coated with poly(lactic-co-glycolic acid) (PLGA) were utilized as a grafting material that does not necessitate primary wound closure. …”
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Plant-Derived Nanovesicles from Soaked Rice Water: A Novel and Sustainable Platform for the Delivery of Natural Anti-Oxidant γ-Oryzanol by Jahnavi Ravilla, Soundaram Rajendran, Vidya M. Basavaraj, Greeshma Satheeshan, Janakiraman Narayanan, Thejaswini Venkatesh, Gopinath M. Sundaram

“…Herein, for the first time, we isolated PDNVs from SRW by the cost-effective Polyethylene glycol 6000(PEG) precipitation method and demonstrated the presence of GO in PDNVs. …”
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Acute administration of lovastatin had no pronounced effect on motor abilities, motor coordination, gait nor simple cognition in a mouse model of Angelman syndrome by Timothy A. Fenton, Stela P. Petkova, Anna Adhikari, Jill L. Silverman

“…Therefore, despite its attractive low toxicity, immediate availability, and low cost of the drug, further investigation for clinical study is unwarranted given the results presented herein.…”
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Survival analysis of length of life and length of productive life in Landlly sows by CHHAYA RANI, ANUJ CHAUHAN, INDRASEN CHAUHAN, SNEHASMITA PANDA, BHARAT BHUSHAN, GYANENDRA KUMAR GAUR, TRIVENI DUTT

“… Survival traits are of major importance in pig breeding as replacing a sow cost more than maintaining a sow in the herd for additional parity. …”
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Unravelling Artemisia species genetic variation via DNA barcoding, ISSR and RAPD with the development of eco-specific SCAR markers by Yasmin A. Mahgoub, Hebaalla A. Mahmoud, Nadia A. El-Sebakhy, Ingy I. Abdallah

“…This provides a reproducible, cost-effective strategy for large-scale authentication of medicinal plants.…”
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Influence of Paratuberculosis Vaccination on the Local Immune Response in Experimentally Infected Calves: An Immunohistochemical Analysis by David Zapico, José Espinosa, María Muñoz, Luis Ernesto Reyes, Julio Benavides, Juan Francisco García Marín, Miguel Fernández

“…Vaccination remains the most cost-effective way to control clinical paratuberculosis in dairy herds, but its effect on the immune response at the intestine have been poorly characterized. …”
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Iron-manganese modified corncob biochar for fluoride removal from groundwater: Insights into adsorption mechanisms by Juan-juan Liu, Si-yuan Ma, Xin-wen Yang, Wang-ying Chen, Abdur Rashid

“…These findings demonstrate that Fe–Mn modified biochar is a highly efficient and cost-effective material for F‒ remediation and holds significant potential for application in contaminated groundwater and soil systems.…”
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Transforming Feather Meal Into a High‐Performance Feed for Broilers by Mandana Salehizadeh, Maryam Tajabadi Ebrahimi, Seyed Naser Mousavi, Abbas Akhavan Sepahi, Reza Orooji

“…ABSTRACT Background The poultry industry faces challenges with the high cost and environmental impact of Soybean meal. Feather meal, a byproduct with low digestibility due to its keratin content, is a potential alternative. …”
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