Anion exchange chromatography-based purification of plant-derived nanovesicles from Brassica oleracea L.: molecular profiling and bioactivity in human cells by Clarissa Zanotti, Clarissa Zanotti, Simona Arena, Sabrina De Pascale, Valentina Ciaravolo, Rosalia Ferracane, Antonio Dario Troise, Chiara Pontecorvi, Francesca Pacello, Chiara Niespolo, Angelo Gismondi, Andrea Scaloni, Mauro Marra

“…However, challenges remain that limit applicative use, including poor knowledge of their interactions with mammalian host cells and primarily the lack of a cost-effective and scalable method to obtain highly purified plant-derived nanovesicles. …”
Get full text

Scoring System for Quantifying the Privacy in Re-Identification of Tabular Datasets by Jakob Folz, Manjitha D. Vidanalage, Robert Aufschlager, Amar Almaini, Michael Heigl, Dalibor Fiala, Martin Schramm

“…However, correlation-only and uniformity-only risk required significantly more processing time, while Markov Model risk incurred the highest computational cost. Despite this, all metrics remained unaffected by the number of quasi-identifiers, except t-closeness, which scaled linearly beyond a certain threshold. …”
Get full text

Comprehensive Metabolomic and Transcriptomic Analysis Revealed the Molecular Basis of the Effects of Different Refrigeration Durations on the Metabolism of <i>Agaricus bisporus</i>... by Zhixin Cai, Zhiheng Zeng, Wenzhi Chen, Zhongjie Guo, Huiqing Zheng, Yuanping Lu, Hui Zeng, Meiyuan Chen

“…<i>Agaricus bisporus</i> is popular worldwide because of its high nutritional value and low cost. Low-temperature storage is a common storage method used for the production and sales of <i>A. bisporus</i> cultivation spawn, but few studies have focused on the physiological and biochemical mechanisms associated with low-temperature storage of <i>A</i>. …”
Get full text

Influence of long-term use of mineral fertilizers on the yield and quality of winter rye grain by F. A. Popov, V. D. Abashev, E. N. Noskova, E. V. Svetlakova, I. V. Lyskova

“…If full fertilizer was applicated in the dose N30Р30К30, prime cost of 1 ton of grain was 3.663 rubles with a total profitability of 91.1 %. …”
Get full text

Action Observation for Children and Adolescents with Cerebral Palsy: Hope or Hype? A Systematic Review with Meta-Analysis by José Fierro-Marrero, Carlos Donato Cabrera-López, Borja Rodríguez de Rivera-Romero, Alejandro López-Mejías, Mirari Ochandorena-Acha, Sergio Lerma-Lara, Roy La Touche

“…Cerebral palsy generates an elevated burden on both patients and health-care systems. Cost-effective therapies such as action observation therapy (AOT), have been proposed to enhance motor performance in these patients. …”
Get full text

Attitudes and acceptance of mRNA-based vaccine for neglected tropical diseases: A multi-country study in Asia by Li Ping Wong, Hai Yen Lee, Haridah Alias, Di Khanh Nguyen, Abhishek Lachyan, Farhana Nishat Seheli, Jamil Ahmed, Zhijian Hu, Yulan Lin

“…Conversely, the belief in the advantages of mRNA-based approaches, such as rapid development, heightened potency, and reduced cost, positively correlates with willingness. High overall knowledge and attitudes scores were associated with a higher willingness to receive vaccines. …”
Get full text

Transforming transnasal endoscopy services: A multicentre service evaluation pilot project by Mohamed Hussein, Jason Dunn, Farhana Sultana-Miah, Sami Hoque, Ahmed Albusoda, Esra Asilmaz, Laura Marelli, Regina Raymond, Mohsen Eldragini, Michael Grimes, Shraddha Gulati, Juriese Saramosing, Mayur Kumar, Eleanor Knights, Vinay Sehgal, Paul Maxwell, Arun Rajendran, Shamima Padaruth, Sophie Stevens, Sergio Coda, Edward Despott, Saswata Banerjee

“…TNE services, particularly with an introduction into outpatients, will improve service capacity in endoscopy, patients will tolerate the procedures more, national 2-week wait and Faster Diagnosis Standard targets will improve, and it is potentially more cost efficient overall.…”
Get full text

Experimental Demonstration of the Distributed Feedback Semiconductor Laser With S-Bent Waveguide and Sampled Grating by Yunshan Zhang, Yuechun Shi, Lianyan Li, Zhengpeng Zou, Jun Lu, Yinchao Du, Wenxuan Wang, Yating Zhou, Xin Chen, Jilin Zheng, Xiangfei Chen

“…The s-bent waveguide and sampled grating can be fabricated simply by the common holography exposure and photolithograph technique resulting in a low cost. Besides, the wavelength accuracy and SLM yield can be improved significantly, which is very beneficial for the multiwavelength DFB laser array.…”
Get full text

Design, construction and efficiency analysis of bagasse-based charcoal packed horizontal lab-scale wetland for the removal of antibiotic-resistant bacteria by Misbah Batool Aslam, Talmeez U. R. Rehman, Amina Farrukh Alavi, Abdul Haleem, Abdul Haq, Safia Ahmed, Wasim Sajjad, Mohammed Bourhia, Ousman B. Mahamat, Khalid S. Almaary, Mahwish Ali

“…These findings emphasize the potential of constructed wetlands with biochar as a sustainable and cost-effective solution for addressing the dual challenges of environmental pollution and antibiotic resistance. …”
Get full text

Optimal PID controller with evolutionary optimization algorithms for rehabilitation robots by Kamran Joyo, Talha Ahmed Khan, Kushsairy Abdul Kadir, Mohd Nizam Bin Husen, Haidawati Mohamad Nasir, Munaza Azhar

“…This research study validates the mathematical models for finding optimizing parameters of the PID, including a comparative study comprising of four diverse cost functions. The objective functions include Integral Absolute Error (IAE) and Integral Squared Error (ISE). …”
Get full text

Epiphytic lichen as a bioindicator of air pollution across selected urban, suburban, and rural areas in Malaysia by Nur Syafiqah Abd Hakim, Asmida Ismail, Mohd Talib Latif, Faezah Pardi, Rosla Zamzuri, Sofia Khalid, Faeiza Buyong

“…Conclusions : This study provides evidence that epiphytic lichen communities respond clearly to varying levels of atmospheric pollution, supporting their use as low-cost, effective bioindicators in tropical regions. …”
Get full text

Study on the spatial and temporal differences and influencing factors of out-of-pocket payments as a share of total health expenditure in China by Xiaoyu Dong, Huaizhi Cheng, Ruotong Tian, Lingxiao Gao, Wenpei Lyu, Jiaqi Zhang, Doudou Huang, Bin Guo

“…SDM shows that the main factors affecting the inter-provincial differences in the OOP proportion in China include the elderly dependency ratio (direct effect − 0.181, indirect effect − 0.585), the child dependency ratio (direct effect 0.292, indirect effect 0.686), per capita GDP(direct effect 11.235), and the proportion of government health expenditure to fiscal expenditure (direct effect − 0.254, indirect effect − 0.994), the average number of medical visits per year (direct effect − 0.444), the expenditure of basic medical insurance (direct effect − 1.519, indirect effect − 3.940), and the average medical cost of outpatients (direct effect 3.142, indirect effect − 10.064). …”
Get full text

Transparent 3-Layered Bacterial Nanocellulose as a Multicompartment and Biomimetic Scaffold for Co-Culturing Cells by Karla Pollyanna Vieira de Oliveira, Michael Yilma Yitayew, Ana Paula Almeida Bastos, Stefanie Cristine Nied Mandrik, Luismar Marques Porto, Maryam Tabrizian

“…These models vary in complexity and cost, ranging from simple and inexpensive to highly sophisticated and costly systems. …”
Get full text

Effect of bundling auricular acupressure and fluid restriction program on salivary flow rate and fluid control adherence among children undergoing hemodialysis: a randomized contro... by Zohour Ibrahim Rashwan, Marwa Mohamed Mahmoud Abdellah, Ferial Moursi, Esraa Mohammed Abd El-Samie Ismail

“…Therefore, nurses working in HD units may adopt this intervention bundle as a cost-effective, safe, and complementary tool to promote sustainable patient adherence to fluid-restriction regimen. …”
Get full text

Comparative analysis of 3D-culture techniques for multicellular colorectal tumour spheroids and development of a novel SW48 3D-model by Carlos Mateos-Sánchez, Beatriz González, Gisela de Miguel-García, Aida Font-Cugat, Iris Marcote-Corral, Sergio Alonso

“…The treatment of regular multi-well plates with anti-adherence solution allows to generate CRC spheroids at significantly lower cost than using cell-repellent multi-well plates. …”
Get full text

Photometric Mapping of Carbonaceous/Siliceous Dust and Water Ice in the ISM with JWST: Applications to the Dense Sightlines by Burcu Günay, Karl D. Gordon, Joshua E. G. Peek, Marjorie Decleir, Dries Van De Putte, Kirill Tchernyshyov, Michael G. Burton

“…This method provides extensive statistical data of the grains across wide fields in the ISM at minimal observing cost. In this study, we present its application on observational data from the literature to validate the measured optical depths and simulations to assess the accuracy of the method under various conditions. …”
Get full text

Desarrollo y aplicación del diagnóstico y pronóstico técnico al mantenimiento de los sistemas centralizados de aire acondicionado // Develop and application of the diagnosis and te... by J. L. Sánchez Ávila, J. V. García Ruano

“…</p><p>____________________________________________________________________</p><p>Abstract:<br />In this paper is exposed the application of the maintenance by diagnosis and technical prediction to the centralized system<br />of air conditioned with heat recovery of the hotel Beautiful LTI Costa; as a solution to the serious problems that the<br />technical management services faces in the tourist facilities to carry out a maintenance with quality and whith smaller cost.<br />The development of an experimental plan, in the hotel facilities, allowed to obtain the curves that express the behavior of<br />the degradation of these systems in the time, as well as to determine the most opportune moment for the realization of the<br />maintenance.…”
Get full text

MODERN VIEWS ON PATHOGENETIC THERAPY OF RHEUMATOID ARTHRITIS by D. G. Rekalov, A. V. Kulynych, S. I. Svistun, E. V. Presnyakova

“…The most effective was induction of long-term response in RA by methotrexate (MTX), while there is a high adherence to treatment, long-term tolerability and low cost treatment. Safe of the DMARD treatment requires careful clinical monitoring of the side effects. …”
Get full text

Characterization of Intsia spp. from Indonesia using microsatellite markers by Purnamila Sulistyawati, Sapto Indrioko, Widiyatno, AYPBC Widyatmoko

“…Despite the potential application of microsatellite markers, their development process often requires high costs, energy, and time. To overcome the limitations, several studies have proposed the use of cross-species amplification, which has proven to be a cost and time-efficient method for obtaining species-specific DNA markers. …”
Get full text

More bang for your buck: potential gains through optimizing maize breeding schemes in sub-Saharan Africa by Davison Chaingeni, Ronica Mukaro, Clay Sneller, Jill E. Cairns, Lennin Musundire, Biswanath Das, Olivia Odiyo, Sammy Madahana, Purity Mazibuko, Washington Mubvereki, Boddupali M. Prasanna, Dumisani Kutywayo

“…The objective of this study was to demonstrate that an easy-to-use deterministic model and a breeding costing tool could identify key modifications to improve the efficiency of breeding within the Zimbabwean national maize breeding program. …”
Get full text