Drugs in Aviation - A Review by G.L. Muntingh

“…Aircrew, like all of us, are prone to illness, but those who take medicine on an inadequately informed basis or undertake self-medication, not only endanger their lives but also jeopardise the safety of passengers and costly aircraft. The Aviation Medicine Department of the South African Civil Aviation Authority, Aviation Medical Examiners, and the Institute for Aviation Medicine receive numerous inquiries regarding the use of medication in the aviation environment. …”
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Evaluating the impact of waste marble on the compressive strength of traditional concrete using machine learning by Kennedy C. Onyelowe, Viroon Kamchoom, Ahmed M. Ebid, Shadi Hanandeh, Susana Monserrat Zurita Polo, Rolando Fabián Zabala Vizuete, Rodney Orlando Santillán Murillo, Rolando Marcel Torres Castillo, Siva Avudaiappan

“…ML offers a powerful alternative to costly and time-consuming laboratory experiments, enabling faster and more sustainable exploration of the potential of waste marble in improving concrete’s compressive strength. …”
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Options to apply national developments in the assessment of sentinel lymph node involvement in breast cancer by M. V. Shomova, E. P. Kulikov, A. N. Demko, I. I. Vinogradov, A. D. Gerasimova, A. N. Budanov

“…In addition, it requires the introduction and improvement of domestic developments, including reducing financial costs.Aim. To study the use of indocyanine green of domestic production (LLC Firm “FERMENT”, Russia) and the IC-GOR detection system (LLC “MedKomplekt”, Russia) for SLN biopsy in patients with early breast cancer.Materials and methods. …”
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Optimasi Algoritma Naive Bayes dengan Diskritisasi K-Means pada Diagnosis Penyakit Jantung by Nafa Fajriati, Budi Prasetiyo

“…Diagnosing heart disease early can help reduce the risk of death and the high costs of treatment for heart disease. Diagnosis of the disease is an important process that must be carried out accurately to avoid misdiagnosis. …”
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High-grade non-muscle invasive urothelial carcinoma in dogs and humans share specific expression of integrin α5β1 by Roberta Lucianò, Maurizio Colecchia, Maurizio Colecchia, Francesca Sanvito, Irene Locatelli, Chiara Venegoni, Alessia Di Coste, Davide Danilo Zani, Angelica Stranieri, Chiara Giudice, Antonella Rigillo, Matteo Gambini, Francesco Montorsi, Francesco Montorsi, Andrea Salonia, Andrea Salonia, Marco Moschini, Massimo Alfano

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STATE BUDGET IN THE CONTEXT OF A WARTIME ECONOMY AND POST-WAR TRIGGERS FOR ITS RECOVERY by Serhii Petrukha, Dmytro Konovalenko, Nina Petrukha

“…It is determined that the key barriers are the lack of domestic financial resources, high level of external debt and significant debt service costs. The impact of international financial assistance on ensuring macroeconomic stability and prospects for improving the efficiency of its use for resource support for economic recovery are also investigated. …”
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Modulation of dopaminergic transmission and brain activity by frontotemporal tDCS: A multimodal PET-MR imaging study by Clara Fonteneau, Inés Merida, Jérome Redoute, Frédéric Haesebaert, Sophie Lancelot, Nicolas Costes, Marine Mondino, Jerome Brunelin

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Adsorption properties of tea polyphenols by hyperbranched poly (amine-ester) by Zhu Qing, Shi Yuanxu, Fan Dongmei, Yu Cuiping, Sun Zhiming, Wang Xiaochang

“…However, this technique involves of organic solvents and complex operational processes, which leads to an environmental pollution and increases the additional costs virtually. The demand for an environment-friendly and cheaper technique in TPs industry is growing rapidly while more people become to pay attention to ambient bio-environment, so seeking for some new methods or new materials is of great significance. …”
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No Long-Term Superiority of Cord-Derived PRP over Autologous PRP in Knee Osteoarthritis: A Prospective Cohort Study by Michele Coviello, Antonella Abate, Giuseppe Maccagnano, Alessandro Geronimo, Elio Caiaffa, Vittorio Nappi, Vincenzo Caiaffa, Giuseppe Solarino

“…Given the limited scientific evidence supporting C-PRP and its higher logistical costs, A-PRP should remain the preferred PRP therapy for knee OA. …”
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Multimodal Web-Based Telerehabilitation for Patients With Post–COVID-19 Condition: Protocol for a Randomized Controlled Trial by Aleksandar Tomaskovic, Vincent Weber, David T Ochmann, Elmo Wanja Neuberger, Ella Lachtermann, Alexandra Brahmer, Nils Haller, Barlo Hillen, Kira Enders, Viktoria Eggert, Peter Zeier, Klaus Lieb, Perikles Simon

“…There is emerging evidence suggesting that exercise and respiratory therapy–based telerehabilitation is safe and could potentially improve physical capacity while reducing health care costs. ObjectiveThis study aims to evaluate the superiority of a multimodal, symptom-titrated telerehabilitation program over standard care in patients with PCC who are severely affected, using the highest oxygen uptake rate (VO2peak [mL/min/kg]) achieved during the cardiopulmonary exercise test (CPET) and minute ventilation/carbon dioxide production slope (VE/VCO2 [full slope]) as primary outcomes. …”
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Influencing patterns of low-temperature nitrogen on the pore structure and oxidation characteristics of lignite by Shuliang XIE, Gang WANG, Qingdong QU, Hao LIU, Lulu SUN

“…Meanwhile, the preparation of liquid nitrogen is complicated and costly. Therefore, in the Wudong Coal Mine in Xinjiang, low-temperature gaseous nitrogen of −40 ℃ was prepared using nitrogen cooling devices and then injected into goaves to prevent the spontaneous combustion of residual coals. …”
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Aprendiendo sobre el Método de los Elementos Finitos. // Learning on the Method of the Finite Elements. by L. L. Otero Pereiro

“…If, this is in this way, then: Which is the reason for which the<br />engineers has a dependence so high of the professionals software, even when the costs of acquisition of these is very high<br />and the research centers or the universities don't dedicate time and efforts to the development of these?…”
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Impact of dietary forage proportion and crossbreeding on feed efficiency and methane emissions in lactating dairy cows by Sabrina Ormston, Tianhai Yan, Xianjiang Chen, Alan W. Gordon, Katerina Theodoridou, Sharon Huws, Sokratis Stergiadis

“…Increasing forage proportion (FP) in the diets of dairy cows would reduce competition for human edible foods and reduce feed costs, particularly in low-input systems. However, increasing FP reduces productivity and may increases methane (CH4) emission parameters. …”
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The potential health impact of restricting less-healthy food and beverage advertising on UK television between 05.30 and 21.00 hours: A modelling study. by Oliver T Mytton, Emma Boyland, Jean Adams, Brendan Collins, Martin O'Connell, Simon J Russell, Kate Smith, Rebekah Stroud, Russell M Viner, Linda J Cobiac

“…We used the following data to parameterise the model: children's exposure to HFSS advertising from AC Nielsen and Broadcasters' Audience Research Board (2015); effect of less-healthy food advertising on acute caloric intake in children from a published meta-analysis; population numbers and all-cause mortality rates from the Human Mortality Database for the UK (2015); body mass index distribution from the Health Survey for England (2016); disability weights for estimating disability-adjusted life years (DALYs) from the Global Burden of Disease Study; and healthcare costs from NHS England programme budgeting data. …”
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Characterization of Chlorine Fixation in Alkaline Metal-Modified Cu-Based Oxygen Carriers for Biomass Chemical Looping Combustion by Dezhe WANG, Yingjie MI, Haodong HUANG, Andong FU, Jinchen MA, Haibo ZHAO

“…Both Ca- and Ba-based oxygen carriers maintained 100% chlorine fixation efficiency, suggesting that lower oxygen-fuel ratios could be utilized in biomass dechlorination processes, thereby reducing carbon capture operating costs. Moreover, doping with Ca and Ba increased the specific surface area and pore volume of the oxygen carriers, increasing the contact area with biomass and thereby stabilizing their performance in CLC. …”
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Soil variation response is mediated by growth trajectories rather than functional traits in a widespread pioneer Neotropical tree by Levionnois, Sébastien, Tysklind, Niklas, Nicolini, Eric, Ferry, Bruno, Troispoux, Valérie, Le Moguedec, Gilles, Morel, Hélène, Stahl, Clément, Coste, Sabrina, Caron, Henri, Heuret, Patrick

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Identification of Plasmodium falciparum and host factors associated with cerebral malaria: description of the protocol for a prospective, case-control study in Benin (NeuroCM) by Valentin Joste, Laurine Maurice, Gwladys I Bertin, Agnès Aubouy, Farid Boumédiène, Sandrine Houzé, Daniel Ajzenberg, Nicolas Argy, Achille Massougbodji, Ida Dossou-Dagba, Maroufou Jules Alao, Michel Cot, Philippe Deloron, Jean-François Faucher, Dissou Affolabi, Hélène Authier, Linda Ayedadjou, Bibiane Biokou, Agnès Coste, Jean-Eudes Degbelo, Latifou Dramane, Sayeh Jafari-Guemouri, Claire Kamaliddin, Elisée Kinkpe, Anaïs Labrunie, Yélé Ladipo, Thomas Lathiere, Audrey Mowendabeka, Jade Papin, Bernard Pipy, Pierre-marie Preux, Marie Raymondeau, Jade Royo, Darius Sossou, Brigitte Techer, Bertin Vianou

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Highly multiplexed molecular inversion probe panel in Plasmodium falciparum targeting common SNPs approximates whole-genome sequencing assessments for selection and relatedness by Karamoko Niaré, Karamoko Niaré, Rebecca Crudale, Abebe A. Fola, Abebe A. Fola, Neeva Wernsman Young, Victor Asua, Victor Asua, Melissa D. Conrad, Pierre Gashema, Anita Ghansah, Stan Hangi, Deus S. Ishengoma, Deus S. Ishengoma, Jean-Baptiste Mazarati, Ayalew Jejaw Zeleke, Philip J. Rosenthal, Abdoulaye A. Djimdé, Abdoulaye A. Djimdé, Jonathan J. Juliano, Jonathan J. Juliano, Jonathan J. Juliano, Jeffrey A. Bailey, Jeffrey A. Bailey

“…While whole-genome sequencing (WGS) is optimal in terms of assessing the entire genome, it is costly for numerous samples. Targeted approaches selectively enriching for the sequence of interest are more affordable and have higher throughput but sometimes lack adequate information content for key analyses.MethodsWe have developed a highly multiplexed molecular inversion probe (MIP) panel (IBC2FULL) targeting 4,264 single-nucleotide polymorphisms (SNPs) with ≥5% minor allele frequency (MAF) in Sub-Saharan African regions from publicly available Plasmodium falciparum WGS (n = 3,693). …”
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Design and evaluation of novel triazole derivatives as potential anti-gout inhibitors: a comprehensive molecular modeling study by Mohammed Er-rajy, Mohammed Er-rajy, Mohamed El fadili, Sara Zarougui, Somdutt Mujwar, Mourad Aloui, Mohammed Zerrouk, Belkheir Hammouti, Larbi Rhazi, Rachid Sabbahi, Mohammed M. Alanazi, Khalil Azzaoui, Khalil Azzaoui, Rachid Salghi, Menana Elhallaoui

“…These computational approaches facilitate drug discovery while reducing research costs.MethodsOur work focuses on a series of synthesized anti-xanthine oxidase inhibitors, aiming to develop new inhibitors. …”
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<i>In vivo</i> evaluation of tropism and biodistribution of synthetic and natural adeno-associated viral vectors by next-generation sequencing by D. O. Maksimov, D. A. Naumova, E. A. Astakhova, V. V. Artemev, S. A. Biryukov, I. S. Abramov, A. A. Navoikova, N. V. Rudev, S. G. Feoktistova, O. V. Glazova, O. N. Mityaeva, P. Yu. Volchkov

“…The optimal solution to minimise the time and costs associated with gene therapy development lies in the improvement of methods aimed at assessing AAV vector biodistribution and transduction efficiency in vivo.AIM. …”
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