The human microbiome-derived antimicrobial lugdunin self-regulates its biosynthesis by a feed-forward mechanism by Leonie Reetz, Lukas Schulze, Thales Kronenberger, Khaled A. Selim, Timm Schaefle, Taulant Dema, Alexander Zipperer, Jens Mößner, Antti Poso, Stephanie Grond, Andreas Peschel, Bernhard Krismer

“…ABSTRACT Many human microbiome members inhibit bacterial competitors by production of antimicrobial compounds whose expression needs to be tightly controlled to balance the costs and benefits of compound biosynthesis. The nasal commensal Staphylococcus lugdunensis outcompetes Staphylococcus aureus using the antimicrobial lugdunin. …”
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Machine Learning-Based Detection of Archeological Sites Using Satellite and Meteorological Data: A Case Study of Funnel Beaker Culture Tombs in Poland by Krystian Kozioł, Natalia Borowiec, Urszula Marmol, Mateusz Rzeszutek, Celso Augusto Guimarães Santos, Jerzy Czerniec

“…The proposed approach not only improves site detection but also reduces operational costs by concentrating resources on optimal survey conditions. …”
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Optimization of Fermentation Parameters for Enhanced Bioethanol Production by Multistress-Tolerant <i>Saccharomycodes ludwigii</i> APRE2 Using Undetoxified Sugarcane Bagasse Hydrol... by Preekamol Klanrit, Sudarat Thanonkeo, Warayutt Pilap, Jirawan Apiraksakorn, Khanittha Fiala, Ratanaporn Leesing, Mamoru Yamada, Pornthap Thanonkeo

“…This approach critically eliminates the need for the costly detoxification pretreatments often required in industrial processes. …”
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Voluntary information and price sharing database – a scoping review of the pricing and procurement landscape across eight Commonwealth Member States by Bridget Kebirungi, Phyllis Ocran, Nduta Kamere, Lynette Keneilwe Mabote, Ngozi Osi, Meghna Joshi-von Heyden, Emily Gilmour, Janneth Mghamba, Layne Robinson, Zaheer-Ud-Din Babar, Helena Rosado, Victoria Rutter

“…This led to the establishment of the Voluntary Information and Price Sharing Database (VIPSD) in 2021, aimed at enhancing procurement transparency, reducing costs, and sharing information on health products amongst member states. …”
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Funding the future: safeguarding pediatric health equity through CMS and CHIP by Carlie N. Myers, Meera Rao, Rishiraj Bandi, Sebastian Densley, Daniella Diaz, Michelle Knecht, Lea Sacca

“…Strengthening CMS-supported programs is essential not only for improving child health outcomes but also for reducing long-term healthcare costs and advancing pediatric health equity.…”
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The effect of antimicrobial stewardship interventions upon antimicrobial consumption and appropriateness in Vietnamese district hospitals: a cluster randomised trialResearch in con... by Jaslyn Doshi, Yen Pham Ngoc, Thu Thuy Ma, Linh Thuy Duong, Van Thi Thuy Pham, Van Giap Vu, Rodney James, Qingbin Li, Quy Trinh Van, Tu Son Nguyen, Thi Thu Trang Tran, Pham Minh Thu Vo, Van An Ngo, Huu Phuc Phan, Ngoc Canh Hoang, Justin Beardsley, Thu Anh Nguyen, Greg J. Fox

“…Secondary outcomes included antimicrobial costs and all-cause mortality. After the intervention period, control sites also received the AMS program. …”
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Effectiveness of an educational asthma management program (CuidAR): the protocol for a cluster-randomized trial in the Brazilian primary healthcare setting by Ana Paula Tussi Leite, Géssica Luana Antunes, Amanda Paz Santos, Ingrid Rodrigues Fernandes, Lauren Sezerá Costa, Tássia Rolim Camargo, Camila Bonalume Dall’ Aqua, Fernando Rovedder Boita, Alessandra da Silva Mota, Mariana Motta Dias da Silva, Mariah Prata Soldi Passos Taube, Bruna Silveira da Rosa, Marcus Herbert Jones, Álvaro A. Cruz, Frederico Friedrich, Paulo M. Pitrez

“…Therefore, an effective educational intervention focused on asthma management in primary health care (PHC) is expected to reduce hospitalization rates, emergency visits, and direct public health costs, improving the quality of life of patients. …”
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PO39 | Bleeding events in Von Willebrand disease type 1 yearly treatable with desmopressin

“…Thus, it can reduce in-hospital admissions and inherent costs, favor adherence and the prompt control of bleeding. …”
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The social care bottleneck: a strategic analysis of A&E wait time reduction by Kieran Kejiou

“…This results in monetary savings by eliminating transaction costs, improving interfaces and co-locating resources. …”
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Two-Year Post-Market Surveillance of iStent inject&amp;reg; W Combined with Phacoemulsification in Japanese Open-Angle Glaucoma Eyes by Inatani M, Kohama I, Chu A

“…At M24, the average monthly glaucoma medication costs decreased by 49.7%.Conclusion: Japanese OAG eyes treated with iStent inject W combined with phacoemulsification experienced reduced IOP and medication burden with minimal adverse events and high success rates over postoperative 2 years.Keywords: minimally invasive glaucoma surgery, trabecular micro-bypass, Japan…”
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Protocol: A mixed-methods study to evaluate implementation and outcomes of U.S. state telemental health policy expansion during the COVID-19 pandemic. by Lucinda B Leung, Jasmeen J Santos, José J Escarce, Susan L Ettner, Claudia Der-Martirosian, Pushpa Raja, Alexander D McCourt, John Fortney, Emma E McGinty

“…<h4>Background</h4>Until the COVID-19 pandemic, it had not been possible to examine the effect of rapid policy changes surrounding telemental health on patient-reported mental health care access, costs, symptoms, and functioning. Sizable variation in telemental health use by patient race-ethnicity, age, and rurality, and in its adoption across healthcare settings, underscores the need to study equitable dissemination and implementation of high-quality telemental health services in the real world. …”
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Effectiveness of a hospital-based work support intervention for female cancer patients - a multi-centre randomised controlled trial. by Sietske J Tamminga, Jos H A M Verbeek, Monique M E M Bos, Guus Fons, Jos J E M Kitzen, Peter W Plaisier, Monique H W Frings-Dresen, Angela G E M de Boer

“…Quality of life and work ability improved statistically over time but did not differ statistically between groups. Work functioning and costs did not differ statistically between groups.…”
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Comparison of the perioperative complications of high intensity focused ultrasound vs. laparoscopic surgery for uterine fibroids: a retrospective study by Li Hu, Chunling Fang, Nenghuan Tang, Fan Xu

“…Secondary outcomes included the Numerical Rating Scale (NRS) for pain assessment, duration of hospital stay, hospitalization costs, and the incidence of short-term postoperative complications within 1 month. …”
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Next-Generation Water Management and Crop Modeling of Sustainable Energy in PLC Based on Agrivoltaics Systems With IoT by Sami Abduljabbar Rashid, Abdalrahman Fatikhan Ataalla, Yousif Al Mashhadany, Sameer Algburi, Norhana Arsad

“…Tackling these issues is essential for improved resource utilization, lowering costs, and promoting sustainable agriculture. This paper proposes an IoT-driven framework for optimizing water management and dynamic crop modelling, ensuring efficient resource utilization in agrivoltaics environments. …”
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Monte Carlo simulation applied to order economic analysis Simulação de Monte Carlo aplicada à análise econômica de pedido by Abraão Freires Saraiva Júnior, Cristiane de Mesquita Tabosa, Reinaldo Pacheco da Costa

“…Finally, it is concluded that the Monte Carlo simulation is effective for treating variable direct costs per unit variability and that the proposed method is useful to support decision-making related to order acceptance.…”
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Prevalence and Antimicrobial Susceptibility of Multi-Drug Resistant Uropathogens in a Tertiary Hospital in Nepal: A One-Year Audit by Manish Man Pradhan, Sangita Sharma, Sujeet Poudyal, Diwas Gnyawali, Suman Adhikari, Suman Chapagain, Bhojraj Luitel, Hari Prasad Kattel, Pawan Raj Chalise

“…It complicates the treatment of infections like urinary tract infections, leading to treatment failure, extended hospital stays, and increased healthcare costs. Empirical antibiotic therapy, guided by local resistance patterns, is crucial for patient outcomes and infection prevention. …”
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Carbon Neutrality of Ukraine as a Determinant of Green Development by Liliia Khomenko, Olena Chygryn, Cetin Bektas, Andriy Iskakov

“…The share of expenditures on the protection of biodiversity and habitat increased to 3.2%, and costs on atmospheric air protection and climate change problems to 19.3%. …”
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Enhanced Blade Fault Diagnosis Using Hybrid Deep Learning: A Comparative Analysis of Traditional Machine Learning and 1D Convolutional Transformer Architecture by Syed Asad Imam, Meng Hee Lim, Ahmed Mohammed Abdelrhman, Iftikhar Ahmad, Mohd Salman Leong

“…Early fault detection and diagnosis are vital and significant concerns for preventing these incidents and are particularly crucial in gas turbines and compressors to avoid costly downtime and maintain optimal plant performance. …”
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Modernization of operating chicory factories using continuous pulsating extractors by D. P. Iovlev, M. I. Farakhov, R. R. Akberov, I. R. Stekolshchikov, A. V. Akhmerov

“…Low capital and operating costs determine the prospects for using CPE for the modernization of existing chicory factories or the creation of new energy-efficient factories.…”
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Medical and social aspects of health security in the formation of public health by O. Sh. Oynotkinova, V. N. Larina

“…To assess the economic costs associated with unhealthy diet and low physical activity, a general approach was used based on the analysis of individual diseases, in particular, type 2 diabetes mellitus, using population attributive fractions, regression method.Results. …”
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