The use of “Acellbia” – a biosimilar of rituximab in systemic sclerosis by L. P. Ananyeva, L. A. Garzanova, O. V. Desinova, R. U. Shayakhmetova, M. N. Starovoytova, O. A. Koneva, O. B. Ovsyannikova, S. I. Glukhova, E. L. Nasonov

“…The “biosimilar” versions of RTX might reduce the cost of therapy and increase patients accessibility to this treatment option. …”
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Effectiveness of Kushal Maa, a group-based mhealth interactive education and social support intervention for maternal and neonatal health outcomes: study protocol for a multisite r... by Praveen Kumar, Lakshmi Gopalakrishnan, Nadia Diamond-Smith, Azaz Khan, Abhishek Singh, Rashmi Bagga, Alison M El Ayadi, Anant Bhan, Alka Ahuja, Pushpendra Singh, Mona Duggal, Jasmeet Kaur, Deepak Tugnawat, Tracy Lin, Sujata Saunik, Garima Singh Verma, Shailendrakumar Gujarathi, Dinesh Chandke, Shashi Kant Dhir, Supriya Dhakne-Palwe, Mrunal Patil, Sonam Kumar, Nitin Vasaikar, Laura Weil

“…The current study seeks to estimate the effectiveness of the Kushal Maa intervention compared with standard care on maternal and neonatal health-related behaviours and health, characterise the mechanisms of intervention impact and evaluate the cost-effectiveness of the Kushal Maa intervention in improving postpartum maternal and neonatal health compared with the standard of care.Methods and analysis We will conduct a prospective, parallel block-randomised controlled trial with a 1:1 allocation ratio among 2100 pregnant women across three geographically diverse Indian states. …”
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Effectiveness of Chemical Management for Broadleaf Weeds in Autumn-Sown Chickpea (Cicer arietinum L.) by Mozhgan Veisi, Mehdi Minbashi Moeini, Sepideh Hatami, Mohammad Saleh Mansouri

“…Farmers in Iran prefer to manage weeds, by hand weeding or using cultivator between rows, due to potential risk of herbicide damages, high cost involved in herbicide applications, and limited herbicide options for selective weed control. …”
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Optimizing fertilizer application and straw return to fields to minimize nitrogen and phosphorus runoff losses in double-rice cropping systems by Ying Zhang, Jian Zhu, Changjun Li, Hua Peng, Ji Liu, Yue Luo, Min Song, Yanjiao Dai, Kai Deng, Xionghui Ji

“…This study emphasizes that P loss in the winter fallow season should not be overlooked, and that combining optimized fertilization with straw return is an eco-friendly, cost-effective measure that lowers N and P losses without crop yields reduction and soil fertility degradation. …”
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A Model For Optimization of Knowledge Management Outsourcing Decision Using Genetic Algorithm by Ameneh Khadivar, Fatemeh Abbasi, Sheyda Akbarian

“…The research also matches findings by Gabi et al. (2004) and Chen and Wang (2009) regarding components such as price, cost, quality, delivery time, and technological capabilities.The genetic algorithm, used as an intelligent tool in this study, allowed for the analysis and optimization of multiple criteria, including managerial capabilities, skilled staff, IT facilities, number of completed projects, technology readiness, and project completion time. …”
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A lethal DENV-2 wild-type mouse model for mutagenesis investigations by Zhiran Qin, Xiaoting Xie, Hua Ye, Hao Wu, Zhuoyun Li, Jingshu Li, Xiaoen He, Zuxin Liang, Xuling Liu, Li Zhu, Qinghua Wu, Weiwei Xiao, Kefeng Wu, Chengsong Wan, Bao Zhang, Zhaohui Sun, Jianhai Yu, Chenguang Shen, Linzhong Yu, Wei Zhao

“…Abstract Background Effective mouse models for testing antiviral medications should be both cost-effective and require minimal labor. Immunodeficient mouse models, such as AG129, are commonly used in dengue virus (DENV) research; however, their high import and maintenance costs make them relatively expensive. …”
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Homologous recombination deficiency (HRD) tests for ovarian cancer: a multicenter French phase II study (HERO) by Raphaël Leman, François Cherifi, Marianne Leheurteur, Pierrick Theret, Camille Pasquesoone, Mathilde Saint-Ghislain, Lucie Bresson, Christophe Denoyelle, Nicolas Vigneron, Laurent Poulain, Raphaël Delepee, Benoit Berby, Julie Dremaux, Aurélie Dumont, Cécile Blanc-Fournier, Corinne Jeanne, Mélanie Briand, Nathalie Rousseau, Louis-Ferdinand Pepin, Elodie Deruche, Fabienne Dumont, Alexandra Leconte, Justine Lequesne, Bénédicte Clarisse, Florence Joly, Laurent Castera, Roman Rouzier

“…Developing new assays is part of the missions of the molecular genetics platforms to improve accessibility and reduce cost compared to non-academic assays. Trial registration IDRCB 2023A0158540, ClinicalTrials.gov NCT06152731 (November 22, 2023). …”
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A generalizable framework for urban wetland training samples generation and migration: A case study of global Ramsar Wetland Cities by Zhe Yang, Weiguo Jiang, Xiaogan Yin, Ziyan Ling, Xiaoya Wang, Miaolong Lin, Shuhui Lai, Xiao Li, Qiaozhen Guo, Zhijie Xiao, Ze Zhang, Qiuling Li, Peiyu Yang, Shihui Huang, Xiang Long, Keyi Yang, Kaifeng Peng, Yongbiao Yu, Xuan Liu, Yaheng Sheng, Xiaorui Ren, Xiangdong Yang, Haicheng Tian

“…Accurate urban wetland mapping requires reliable training samples, yet the cost reduction and efficiency enhancement of sample production in complex urban backgrounds remains challenging. …”
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Li-rich oxide micro-bricks with exposed {010} planes to construct ultrahigh-compaction hierarchical cathodes for Li-ion batteries by Yongjian Li, Tong Sun, Chenxing Yang, Yuefeng Su, Cai Liu, Xinyu Zhu, Yihong Wang, Siyuan Ma, Xinyu Wang, Yizhi Zhai, Wenlong Kang, Lai Chen, Meng Wang, Liang Zhang, Bin Wang, Qing Huang, Yibiao Guan, Feng Wu, Ning Li

“…Although lithium-rich manganese-based (LRM) cathode materials have high capacity (> ​250 ​mAh ​g−1) due to their multi-electron redox mechanisms and offer cost advantages due to their high Mn content, challenges remain before they can achieve commercialization as replacements for lithium cobalt oxides which have high volumetric energy density. …”
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Consumption of elephant and mammoth ivory increases in southern China by Lucy Vigne, Esmond Martin

“…Similar privately owned ivory in 2010 cost USD 750/kg, according to various sources. High quality Siberian mammoth tusks were approximately USD 400/kg (wholesale) in 2010 in China. …”
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Research progress and cultivation strategies for ratoon rice under mechanical harvesting conditions(机械收割条件下再生稻研究进展及栽培策略) by 林文芳(LIN Wenfang), 郭春林(GUO Chunlin), 兰超杰(LAN Chaojie), 谢粤斌(XIE Yuebin), 秦彬(QIN Bin), 詹国明(ZHAN Guoming), 王顺(WANG Shun), 汪嘉瑶(WANG Jiayao), 林文雄(LIN Wenxiong)

“…This approach offers significant cost savings in terms of seed, fertilizer, labor, and time, while it also ensures exceptional rice quality and promotes environmental sustainability. …”
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Health and associated economic benefits of reduced air pollution and increased physical activity from climate change policies in the UK by Heather Walton, David Dajnak, Mike Holland, Dimitris Evangelopoulos, Dylan Wood, Christian Brand, Nosha Assareh, Gregor Stewart, Andrew Beddows, Shawn YC Lee, Daniela Fecht, Yunzhe Liu, Bethan Davies, Anna Goodman, Tuan Vu, Sean Beevers

“…Total yearly monetised benefits for BNZP vs BAU summed to 2154 (air pollution/active travel) were £153 (122 to 184) billion (core); 278 (228 to 334) billion (+outcomes with weaker evidence).Adding the effects of air pollution reductions on disease incidence, with effects of air pollution and physical activity on mortality, increases the monetised benefits that may justify Net Zero policies in cost-benefit analysis.…”
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Shared health challenges, political divides: can South Asia heal itself? by Akhtar Sherin

“…The SEAR-EMRO divide further weakened the region’s COVID-19 response; while India’s vaccine production supported SEAR countries, Pakistan and Afghanistan (EMRO) faced high-cost import dependency and limited access. Disrupted supply chains and lack of cross-border coordination led to delays and deepened disparities.20,21 A unified, regionally grounded approach could strengthen health cooperation, policy integration, and public health outcomes across South Asia. …”
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Appropriate time interval to update ambiguous genetic diagnosis in inherited arrhythmogenic syndromes by Estefanía Martínez-Barrios, Andrea Greco, Sergi Cesar, Carles Díez-López, José Cruzalegui, Nuria Díez-Escuté, Patricia Cerralbo, Fredy Chipa, Irene Zschaeck, Simone Grassi, Antonio Oliva, Norma Balderrábano, Rocío Toro, Georgia Sarquella-Brugada, Oscar Campuzano

“…There are still questions to be resolved regarding the legal responsibility or who should assume the economic cost of updating a genetic diagnosis.…”
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Construction of a novel online calculator for prediction of osteoporosis risk in Chinese type 2 diabetes patients by Xing Yu, Wenchi Liu, Xiaojun Chen, Yicheng Wang, Huibin Tang, Yunyun Su, Liangdi Xie, Li Luo

“…The screening model provides an accurate, user-friendly, and low-cost tool for the early diagnosis of osteoporosis in people with T2D from China.…”
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Wide-Bandgap All-Inorganic CsPbIBr₂ Top Cells With MoO_x/Ag/TeO₂ Composite Transparent Anode Towards Efficient Four-Terminal Perovskit... by Fengqin He, Wuxiong Fei, Yilin Wang, Chenbo Liu, Qirui Guo, Wensheng Lan, Gang Fan, Gang Lu, Dazheng Chen, Weidong Zhu, He Xi, Chunfu Zhang

“…Therefore, the tandem of Si cell and CsPbIBr₂ cell with optimized MoO_x(20 nm)/Ag(8 nm)/TeO₂(50 nm) transparent electrode could be the promising cost-effective photovoltaic in the future. This work is instructive to the fabrication of pervoskite/Si tandem solar cells.…”
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Examining the feasibility of a crisis-focused Cognitive Behaviour Therapy (CBT)–informed psychological intervention for inpatients experiencing psychosis (the CRISIS study): result... by Lisa Wood, Anthony P. Morrison, Mary Birken, Ceri Dare, Ella Guerin, Patrick Nyikavaranda, Nira Malde-Shah, Karen Persaud, Panarai Ford, Cyntheia Nebo, Caroline S. Clarke, Brynmor Lloyd-Evans, Kathryn Greenwood, Glyn Lewis, Barbara Lay, Graeme MacLennan, Nicola Morant, Fiona Nolan, Vanessa Pinfold, Colette Christiansen, Claire Williams, Sonia Johnson

“…A further large-scale fully powered trial is required to evaluate its effectiveness and cost-effectiveness, including modified strategies for follow-up data collection. …”
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The clinical impact of 16S ribosomal RNA PCR and sequencing in the identification of bacterial infections: a 7-year report from a Lebanese tertiary care center by Nour Youssef, Nour Youssef, Celina F. Boutros, Fatima Dakroub, Fata Akl, Lina Reslan, Marc Finianos, Mohammad Bahij M. Moumneh, Tarek Bou Dargham, Zeinab El Zein, Zeinab El Zein, Zeinab El Zein, Amani Haddara, Rawan Korman, Sarah Khafaja, Sarah Khafaja, Sarah Khafaja, Ghassan Matar, Ghassan Matar, George F. Araj, George F. Araj, Ghassan S. Dbaibo, Ghassan S. Dbaibo, Ghassan S. Dbaibo

“…Shorter turnaround time, improved patient management, and cost-effectiveness are key factors to consider when advocating for the broader adoption of 16S testing.…”
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Effect of the time factor on the hydraulic activity of mechanically activated saponin-containing powder by Marina V. Morozova, Maria A. Frolova

“…The article examines the problem of the development of transport infrastructure in the Solovetsky archipelago and proposes a solution to reduce the cost of manufacturing reinforced concrete slabs for the road surface. …”
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The Effect of Landscape Pattern on Urban Temperature Changes in Hamadan by Marziye Shojaei, Kamran Shayesteh, Behnaz Attaeian

“…The metrics are used as quantitative indicators for measuring and describing landscape patterns. 2-Materials and Methods For land surface temperature analysis, the advantage of satellite temperature data is advantageous due to the limited number of synoptic stations in the city and the high cost of collecting terrestrial data. It is possible to identify urban microclimate details with the help of satellite images obtained from surface heating patterns. …”
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