Antioxidant and Anti-Inflammatory Effects of Traditional Medicinal Plants for Urolithiasis: A Scoping Review by Brenda Pacheco-Hernández, Teresa Ayora-Talavera, Julia Cano-Sosa, Lilia G. Noriega, Neith Aracely Pacheco-López, Juan M. Vargas-Morales, Isabel Medina-Vera, Martha Guevara-Cruz, Rodolfo Chim-Aké, Ana Ligia Gutiérrez-Solis, Roberto Lugo, Azalia Avila-Nava

“…Thus, strategies have been sought to reduce it and one of them is the use of medicinal plants due to their accessibility, low cost, and cultural traditions. Studies on traditional medicinal plants in UL mainly documented results of litholytic and urinary parameters. …”
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Extraction of natural antioxidants from Moroccan saffron (Crocus sativus L.) using ultrasound-assisted extraction: An optimization approach with box-behnken design by Chaimae Slimani, Mouhcine Fadil, Chaimae Rais, Laila El-hanafi, Meryem Benjelloun, Hyeong-Moo Shin, John P. Giesy, Abderrahim Lazraq, Mahmoud M.A. Abulmeaty, Khalid M. Almutairi, Mourad A.M. Aboul-Soud

“…Exploring large-scale UAE systems, evaluating cost-effectiveness, and identifying potential adaptations for commercial production would be highly beneficial.…”
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Study design and procedures for a hybrid effectiveness-implementation incomplete stepped-wedge cluster-randomized trial to evaluate a differentiated point-of-care HIV diagnosis and... by Michael E. Herce, Caitlin Cassidy, Alexandra Munson, Jessie K. Edwards, Sarah E. Rutstein, Mitch Matoga, Chimwemwe Kumwenda, Katherine R. Simon, Joep J. van Oosterhout, Carrie M. Cox, Funny Kamanga, Wiza Kumwenda, Sam Phiri, Ethel Rambiki, Agness Thawani, Jacqueline Huwa, Bridget Malewezi, Tisu Mvalo, Agatha Bula, Lameck Chinula, Irving Hoffman, Madeleine A. Squibb, Rose K. Nyirenda, Friday Saidi, Mina C. Hosseinipour, Maganizo B. Chagomerana

“…Implementation outcomes of acceptability, adoption, fidelity, implementation, sustainability, cost, and scalability will be assessed using convergent mixed methods. …”
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Analysis of Management Factors Affecting Irrigated Wheat (Triticum aestivum L.) Yield Gap in Different Regions of Lorestan Province using the Comparative Performance Analysis (CPA)... by Alinazar Nazari, Afshin Soltani, Ebrahim Zeinali, Alireza Nehbandani

“…Since variables such as crop rotation, use of appropriate cultivars, number of irrigations, number of plowings, and planting date have a greater impact on the yield gap, optimizing these factors can significantly boost irrigated wheat yields. Considering the cost–income ratio, such optimizations would also be more profitable for farmers in the studied counties.…”
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Optimizing irrigation and nitrogen levels to achieve sustainable rice productivity and profitability by Mohd Salim Mir, Waseem Raja, Raihana Habib Kanth, Eajaz Ahmad Dar, Zahoor Ahmad Shah, Mohammad Anwar Bhat, Aamir Hassan Mir, Fehim Jeelani Wani, Tauseef A. Bhat, Javid Ahmad Bhat, Baby Summuna, Umer Fayaz, Suhail Fayaz, Bilal Ahmad Bhat, Nadhir Al‑Ansari, Mohamed A. Mattar, Ali Salem

“…Applying nitrogen at 125% RDN (Recommended dose of nitrogen) and irrigation water at field capacity produced the highest benefit–cost ratio (1.64), which was closely followed by the same irrigation regime and 100% RDN application (1.60 BC ratio). …”
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A Multicenter Study on the Challenges and Real-World Utilization of Immune Checkpoint Inhibitors in Resource-Constrained Settings: Insights and Implications from India by Ashwin Oommen Philips, Sunu Cyriac, P. Unnikrishnan, Anil T. Jose, Krishnakumar Rathnam, S.V. Saju, Smita Kayal, Soumya Surath Panda, Lalatendu Moharana, Sindhu Kilaru, Amit Sehrawat, Deepak Sundriyal, Puneet Dhamija, Deepak Jain, Pamela Alice K., Jaineet Sachdeva, Nishant Batta, Raman Arora, Yogesh Arora, Harpreet Singh, Mridul Anand, Ishu Sharma, Prasanth Ganesan

“…However, in the absence of biosimilars, cost remains a significant barrier. Solutions to increase access include using lower doses, which may be as effective.…”
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Development of a double-antigen sandwich ELISA for rapid and accurate detection of antibodies against Capripoxvirus by Wanying Wang, Zhengwang Shi, Juncong Luo, Huancheng Liao, Lu Feng, Yuqian Zhu, Yongyu Lin, Xintai Shi, Fan Zhang, Tao Xi, Jie Chen, Hong Tian, Haixue Zheng

“…This method features high sensitivity and specificity, is cost-effective, simple, reproducible, and suitable for extensive testing. …”
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CAP-m7G: A capsule network-based framework for specific RNA N7-methylguanosine site identification using image encoding and reconstruction layers by Peilin Xie, Jiahui Guan, Xuxin He, Zhihao Zhao, Yilin Guo, Zhenglong Sun, Lantian Yao, Tzong-Yi Lee, Ying-Chih Chiang

“…Accurate identification of m7G sites is thus essential for elucidating these mechanisms. Due to the high cost of experimentally validating m7G sites, several artificial intelligence models have been developed to predict these sites. …”
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Diversity of Bioactive Compounds in Microalgae: Key Classes and Functional Applications by Maslin Osathanunkul, Suebsuya Thanaporn, Lefkothea Karapetsi, Georgia Maria Nteve, Emmanouil Pratsinakis, Eleni Stefanidou, Giorgos Lagiotis, Eleni Avramidou, Lydia Zorxzobokou, Georgia Tsintzou, Artemis Athanasiou, Sofia Mpelai, Constantinos Constandinidis, Panagiota Pantiora, Marián Merino, José Luis Mullor, Luka Dobrovic, Leonardo Cerasino, Tomohisa Ogawa, Meropi Tsaousi, Alexandre M. C. Rodrigues, Helena Cardoso, Rita Pires, Daniel Figueiredo, Inês F. Costa, Catarina Anjos, Nikolaos E. Labrou, Panagiotis Madesis

“…The GRAS status of several species facilitates market integration, but challenges in scaling and cost reduction remain. Advances in biotechnology and metabolic engineering will optimize production, driving growth in the global microalgae industry. …”
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Enhancing drought tolerance in Pisum sativum and Vicia faba through interspecific interactions with a mixed inoculum of Rhizobium laguerreae and non-host beneficial rhizobacteria by Asma Hami, Imane El Attar, Imane El Attar, Najoua Mghazli, Najoua Mghazli, Salah Ennajeh, El Houcine Ait-Ouakrim, Meryeme Bennis, Meryeme Bennis, Said Oulghazi, Bouabid Badaoui, Bouabid Badaoui, Jamal Aurag, Laila Sbabou, Kaoutar Taha

“…IntroductionHarnessing plant growth-promoting rhizobia presents a sustainable and cost-effective method to enhance crop performance, particularly under drought stress. …”
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Beyond BMI: a comprehensive approach to pediatric obesity assessment by Norma Cipatli Ayuzo Del Valle, Norma Cipatli Ayuzo Del Valle, Perla Pérez-Treviño, Ana Carla Cepeda Lopez, Ana Carla Cepeda Lopez, Regina M. Murillo-Torres, Elena Cristina Castillo, Diego Gutierrez-Cantu, Oscar Tamez-Rivera, Oscar Tamez-Rivera, Mayela Paez Flores, Isabella Flores-Ayuzo, Luis Alberto Luévano-Martinez, Sergio Javier Fernandez Ortiz, Sergio Javier Fernandez Ortiz, Noemí García, Leonardo Mancillas-Adame

“…Although bioelectrical impedance analysis was selected due to its practicality, cost-effectiveness, and non-invasiveness, it has inherent measurement variability compared to dual-energy x-ray absorptiometry. …”
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Evaluating the Fiscal Impact of Antiretroviral Therapy for the Management of HIV in the United States 1987–2023 by Paquete AT, Mordi U, Jarrett J, Thaliffdeen R, Chaudhari P, Connolly MP, Kotsopoulos N, Sullivan PS

“…The reduction of healthcare costs for HIV care financed by the government was also considered. …”
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Digital education and exercise therapy versus minimal intervention for young people at high risk of early onset knee osteoarthritis after ACL reconstruction: a study protocol for t... by Jackie L. Whittaker, Amanda Cammalleri, Candice Archibald, Alexandra Brooks-Hill, Patrick Chin, Sarah Clark, Jennifer C. Davis, Alison M. Hoens, Michael A. Hunt, Karin Kausky, Angelina Ko, Lise Leveille, Linda C. Li, Parth Lodhia, Justin M. Losciale, Maxi Miciak, Amber D. Mosewich, Adnan Sheikh, Trish Silvester-Lee, Linda K. Truong, Dominic Wade, David R. Wilson, Hui Xie, Xian He Yan, Ewa M. Roos

“…We will also assess secondary implementation (perceived barriers and facilitators of SOAR delivery), secondary efficiency (incremental cost-utility ratio), and exploratory outcomes. Missing data will be imputed and blinded intention-to-treat analyses performed. …”
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Quantifying sedimentary ’blue carbon’ in relation to canopy cover in the seagrass meadows of Turneffe Atoll, Belize by Stacey L. Felgate, Stacey L. Felgate, Stacey L. Felgate, Richard Sanders, Richard Sanders, Valdemar Andrade, Christopher D. G. Barry, Hannah Brittain, Stephen Carpenter, Stephen Carpenter, Abel Carrias, Eliceo Cobb, Chris D. Evans, James Hunt, Anna Lichtschlag, Daniel J. Mayor, Kate Peel, David M. Price, Freya Radford, Arlene Young, Claire Evans

“…Substantial Corg stocks extending >1m depth were observed across all sites, and so these inventories are considered conservative.DiscussionA preliminary ‘cost of loss’ for sedimentary Corg in the top 30 cm of Turneffe Atoll’s seagrass meadows, based on a carbon trading value of €60 tCO2 (eq), is estimated at €42 million for the outer atoll, increasing to €136 million when the mangrove-derived sediments of the central atoll are considered and €260 million when turbid areas are assumed to contain seagrass.…”
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Advanced strategy for cancer detection based on volatile organic compounds in breath by Ziqi Jia, Yiwen Jiang, Tongxuan Shang, Heng Cao, Jiayi Li, Lin Cong, Pengming Pu, Hengyi Xu, Yuchen Liu, Yansong Huang, Dongxu Ma, Jiang Wu, Ruijie Zhou, Xiang Wang, Chang bao Han, Jiaqi Liu

“…Abstract The analysis of volatile organic compounds (VOCs) in exhaled breath has emerged as a promising non-invasive approach for cancer diagnosis, offering advantages in speed, safety, cost-effectiveness, and real-time monitoring. Two primary methodologies are employed for VOCs detection: mass spectrometry (MS)-based techniques, which provide high-precision identification and quantification of individual compounds, and sensor-based pattern recognition methods, which detect disease-specific VOC signatures. …”
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Potential of digital applications for self-management and other outcomes in inflammatory rheumatic diseases: a systematic literature review by Alina Volkmar, Cay-Benedict von der Decken, Cay-Benedict von der Decken, Cay-Benedict von der Decken, Cay-Benedict von der Decken, Stefan Kleinert, Stefan Kleinert, Kirsten Karberg, Kirsten Karberg, Georg Gauler, Georg Gauler, Michael Klennert, Jana Klennert, Peer Malte Aries, Peer Malte Aries, Sonja Froschauer, Sarah Wildenhain, Theresia Muth, Susanna Späthling-Mestekemper, Susanna Späthling-Mestekemper, Christoph Kuhn, Christoph Kuhn, Wolfgang Vorbrüggen, Wolfgang Vorbrüggen, Martin Welcker, Martin Welcker, Peter Bartz-Bazzanella, Peter Bartz-Bazzanella, Matthias Englbrecht

“…Variability in study design, sample size, and intervention duration posed challenges for drawing definitive conclusions about the effectiveness of digital interventions.DiscussionDigital health applications show promise as cost-effective and scalable solutions to complement standard IRD care by empowering patients in their disease management. …”
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Clinical characteristic of isolated thrombocytopenia in patients with bone marrow failure-related germline variants: a retrospective study from a single centre by Nanxi Dong, Jingjie Dong, Chuanao Xin, Peicheng Wang, Yaonan Hong, Rudan Zheng, Zexing Sun, Qi Liu, Yingying Shen, Xiawan Yang, Yiping Shen, Jianping Shen, Baodong Ye, Yuhong Zhou, Dijiong Wu

“…While whole-exome sequencing (WES) detects these variants, its cost limits routine use. This study compares prognosis and clinical features of isolated thrombocytopenia in patients with ITGV-BMFsand those with classic ITP.Methods The clinical data of patients diagnosed with ITGV-BMFs were retrospectively analyzed and compared with those of patients with classic ITP from August 2018 to February 2024. …”
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Method for compensating multi-time measurement data of distribution network based on alternating minimization matrix completion combined with VMD-ARIMA-LSTM by Xiaodan Yu, Ruijia Jiang, Xiaolong Jin, Hongjie Jia, Yunfei Mu, Wei Wei, Wanxin Tang

“…However, the increasing complexity of network structure and the high installation cost of measurement equipment introduce operational challenges including state variability and measurement data incompleteness. …”
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Effect of four tillage methods on the physical properties and loss of soil in the potato–grass rotation in hillside areas of a high Andean region in Colombia Efecto de cuatro mét... by Ramírez Luís, Chaparro Anaya Oscar, Bernal Napoleón, Ipaz Sandro, Montealegre Guillermo

“…ATT generated the bigger cost–reducing and environmental retribution, because his production (13 tha<sup>–1</sup>) was major than the average obtained in the treatments (12.4 tha<sup>–1</sup>) and the lost one belonging to ground was minor than the generated for MT and CMT.…”
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Health Beliefs and Obesity Bias as Determinants of Attitudes Toward the Rising Tides of GLP-1 Medications: Mounjaro and Ozempic by Al-Mahzoum K, Abdelaziz DH, Alenezi F, Almutairi J, Alsubaiei MK, Alharbi AB, Al-Rawi S, Al-Rawi S, Bousheheri FF, Alhajri AH, Alajmi SN, Sallam M, Mansour NO, Alnazly EK, Sallam M

“…The negative attitudes observed likely reflect concerns about side effects, cost, and accessibility of these medications. The findings highlighted the need for targeted education in Arab countries to address obesity bias and encourage a balanced evaluation of the benefits and risks of GLP-1 drugs for weight management.Keywords: obesity BIAs, GLP-1 medications, mounjaro, ozempic, health beliefs, weight management, pharmacological interventions…”
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