The Financial, Economic and Political Risk of Trader Partners on the Import of Virtual Water of Oilseeds to Iran by F. Fathi, M. Behnam

“…In other words, the Iranian government should accept the risk of importing oilseeds from neighboring and regional markets that are closer, rather than necessarily from the production hub. This may reduce the cost of importing this product by choosing these countries. …”
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Multi-Objective Optimization of Machine Learning-Based Nonlinear Equalizers for Digital Coherent Optical Interconnects by Lucas C. Dantas, Hildo Guillardi Junior, Plinio Dester, Rafael A. Penchel, Jose Augusto de Oliveira, Marcelo L. F. Abbade, Leandra I. Abreu, Jinlong Wei, Ivan Aldaya

“…This work presents a multi-objective optimization approach for nonlinear equalization, balancing performance and computational cost. A sequentialized multilayer perceptron (MLP)-based nonlinear equalizer is applied to a 16-QAM digital coherent optical system over a 150 km uncompensated link at 112 Gbps. …”
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Study of bases influence on the biopharmaceutical characteristics of the pastes for onychomycosis therapy by V. V. Luc, V. V. Gladyshev, A.P. Lisyanskaya, A.D. Diudiun

“…Also wide application is limited to length of use (from 6 month to 1 year) and high therapy cost. According to above mentioned information, development of specific semisolid dosage form for onychomycosis therapy without removing the nail plate and allowing combination high efficacy of medical substances even in case of nail-bed affection, rational term of treatment and economical availability is rational. …”
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An amplicon-based approach for full-genome characterization of HPV16 by Isabelle Malet, Inès Draa, Valentin Leducq, Fanny Vuong, Pascale Bonnafous, Anne-Geneviève Marcelin, Vincent Calvez, Aude Jary

“…This approach shows good sensibility and specificity with limited cost, opening new perspectives in the field of whole-genome HPV sequencing.IMPORTANCEHPV16 is by far the most oncogenic genotype, so characterizing the genetic variability of its genome is important to better understand the link with its transforming role. …”
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A Radiomic-based model to predict the depth of myometrial invasion in endometrial cancer on ultrasound images by Francesca Arezzo, Annarita Fanizzi, Rosanna Mancari, Emiliano Cocco, Samantha Bove, Maria Colomba Comes, Mariangela Gianciotta, Giorgia Lanza, Salvatore Lopez, Gerardo Cazzato, Erica Silvestris, Elsa Vitale, Enrico Vizza, Gennaro Cormio, Raffaella Massafra, Vera Loizzi

“…They can represent a valid support tool for the clinicians for an accurate estimate of the deep myometrial infiltration already in the diagnosis phase with an easily accessible, low-cost examination that causes no discomfort for the patient such as ultrasound.…”
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Developing and validating machine learning models to predict next-day extubation by Samuel W. Fenske, Alec Peltekian, Mengjia Kang, Nikolay S. Markov, Mengou Zhu, Kevin Grudzinski, Melissa J. Bak, Anna Pawlowski, Vishu Gupta, Yuwei Mao, Stanislav Bratchikov, Thomas Stoeger, Luke V. Rasmussen, Alok N. Choudhary, Alexander V. Misharin, Benjamin D. Singer, G. R. Scott Budinger, Richard G. Wunderink, Ankit Agrawal, Catherine A. Gao, NU SCRIPT Study Investigators

“…However, any ML-based model should be compared with protocol-based practice in a prospective, randomized controlled trial to determine improvement in outcomes while maintaining safety as well as cost effectiveness.…”
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A Smart Semi‐Implantable Device Integrating Microchannel‐Enhanced Sampling and Multiplex Biochemical Testing for Deep Wound Monitoring and Pathogen Identification by Qilin Li, Chunyu Wei, Luming Xu, Jiao Zhang, Yuyu Li, Xiaohuan Lu, Rengui Xu, Honglian Guo, Peng Cao, Chenke Ouyang, Jiarong Xu, Wei Chen, Zheng Wang, Lin Wang

“…Coupled with the device's favorable biocompatibility and cost‐effectiveness, this intelligent system emerges as a promising tool for safe and effective management of complicated deep wounds.…”
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Leveling up engagement: gamification’s role in creating immersive online events by Samuel I. M. Horita, Beatriz M. S. Gonzaga, Renata M. F. Mélo, Aline B. M. Rodrigues, Aline T. Ferreira, Andreon S. M. Silva, Anne C. S. B. Marcos, Giovane F. S. Junior, Hugo A. S. Souza, João P. S. Oliveira-Correia, Lorrane A. Pereira, Mayara M. L. Carvalho, Norma C. C. Brandão, Raissa S. L. Rosa, Thiago M. Ribeiro, Yuli R. M. Souza, Mariana Alberti Gonçalves, Roberto R. Ferreira, Ingo Riederer, Andrea Henriques Pons, Luciana R. Garzoni, Tania C. Araujo-Jorge, Clélia C. Mello-Silva

“…Abstract Virtual conferences can be easily accessed, promotes audience diversity, and leads to cost reduction. However, motivation and social interaction need amelioration. …”
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Oxidative genomic damage in pediatric patients exposed to mercury released by dental amalgam by Guadalupe Nalleli Macías-Lamas, Yveth Marlene Ortiz-García, Blanca Patricia Lazalde-Ramos, Guillermo Moisés Zúñiga-González, Belinda Claudia Gómez-Meda, Cristina Hermila Martínez-Bugarín, Susana Vanessa Sánchez-De-La-Rosa, Saulo Oswaldo Sánchez-Rivera, Gabriela Morales-Velazquez, Celia Guerrero-Velázquez, Ana Lourdes Zamora-Perez

“…Abstract Background Mercury (Hg) is the major component of dental amalgam which has been utilized for decades because it is durable, inexpensive and easy to manipulate and position, as well as having a relatively low cost. Hg from dental amalgam fillings has been shown to be released into the buccal cavity due to processes such as abrasion and corrosion, and which could represent a continuous source of oxidative damage to mouth tissues. …”
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Outcomes of Implementing a Multidimensional Antimicrobial Stewardship Program in a Medical Ward in a Third-Level University Hospital in Northern Italy by Maria Mazzitelli, Daniele Mengato, Gianmaria Barbato, Sara Lo Menzo, Fabio Dalla Valle, Margherita Boschetto, Paola Stano, Cristina Contessa, Daniele Donà, Vincenzo Scaglione, Giacomo Berti, Elisabetta Mariavittoria Giunco, Tiziano Martello, Francesca Venturini, Ignazio Castagliuolo, Michele Tessarin, Paolo Simioni, Annamaria Cattelan

“…No significant changes in LOS or mortality were observed. Antimicrobial costs fell by 48.8% (with EUR 57,100 saved). <b>Conclusions</b>: ASP reduced antimicrobial consumption, improved prescription quality, and cut costs without compromising patient outcomes. …”
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卒中院前急救与血压管理的挑战与突破：从现状到未来（Challenges and Breakthroughs in Prehospital Emergency Care and Blood Pressure Management for Stroke: Current Status and Future Directions）... by 陈晨，刘飞凤，熊昕丽，汤跃宇，李刚（CHEN Chen, LIU Feifeng1, XIONG Xinli, TANG Yueyu, LI Gang）

“…Currently, there is a lack of low-cost and easily implementable methods for prehospital stroke subtype diagnosis. …”
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Highly efficient NIR-II photothermal therapy amplified ROS oxide breast tumor therapy by mesoporous gallium-enriched platinum nanomedicine by Yunfei Ying, Yonghui Su, Ao Wang, Tingting Li, Hongjun Zhuang, Siyaqi Li, Xiaolong Liu, Kecan Lin, Peiyuan Wang, Fuxing Zhang

“…Rational design and exploitation of nanomaterials with superior treatment properties for suitable indications is a way out to relieve cost constraint of therapy and solve the unsatisfactory efficacy for cancer patients. …”
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Clinical efficacy analysis of arthroscopically assisted orthcord suture fixation in the treatment of tibial intercondylar eminence fractures: a retrospective comparative cohort stu... by Rongfang Zhang, Yuqi Wang, Xinyue Jia, Yuanxin Qiao, HongBo Liu

“…At the same time, the cost of Orthcord suture surgery (1310.7 ± 0.29) $ was significantly lower than that of the other two groups (P<0.05). …”
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Immediate versus Delayed Sequential Bilateral Cataract Surgery: A Systematic Review and Meta-Analysis. by Monali S Malvankar-Mehta, Yufeng Nancy Chen, Sangita Patel, Angela Pui-Kei Leung, Man Mohan Merchea, William G Hodge

“…The hospital may benefit due to lower cost.<h4>Objective</h4>To perform a systematic review and meta-analysis to evaluate ISBCS and DSBCS.…”
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Glucocorticoids and immunoglobulin alone or in combination in the treatment of multisystemic inflammatory syndrome in children: a systematic review and network meta-analysis by Junjie Lin, Junjie Lin, Qiang Tong, Hui Huang, Jiahui Liu, Ye Kang, Siyuan Liu, Weiyi Wang, Tianshu Ren, Tianshu Ren, Yuan Yuan

“…However, given its high cost and limited availability in numerous countries, there is a pressing need for evidence to validate alternative therapeutic options.ObjectiveTo evaluate the efficacy of glucocorticoids (GCs), IVIG, and combination therapy for the treatment of Children with MIS-C.Data sourcesPubMed, Cochrane Library, EMBASE, Web of Science, and Medellín. …”
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Performance validation of deep-learning-based approach in stool examination by Kristal Dale Felimon Corpuz, Teera Kusolsuk, Benjamaporn Wongphan, Putza Chonsawat, Kaung Myat Naing, Siridech Boonsang, Veerayuth Kittichai, Chia-Kwung Fan, Santhad Chuwongin, Dorn Watthanakulpanich

“…Despite advancements in molecular methods with higher sensitivity and specificity, the Kato-Katz or formalin-ethyl acetate centrifugation technique (FECT) remains the gold standard and a routine diagnostic procedure suitable for its simplicity and cost-effectiveness. However, these techniques have limitations that must be addressed. …”
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To be climate-friendly, food-based dietary guidelines must include limits on total meat consumption – modeling from the case of France by Emmanuelle Kesse-Guyot, Julia Baudry, Justine Berlivet, Elie Perraud, Chantal Julia, Mathilde Touvier, Benjamin Allès, Denis Lairon, Serge Hercberg, Hélène Fouillet, Philippe Pointereau, François Mariotti

“…A similar shape was observed for CED, LO, and Health Risk Score, but costs were consistently higher than in the observed diet, and exhibited a U-shape. …”
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A novel methodology for the extraction, purification and characterization of immunoglobulin G (IgG) nanoparticles from bovine colostrum: implications for food and therapeutic indus... by Fawze Alnadari, Yusof A.Y.A. Mohammed, Mustapha Muhammad Nasiru, Amirah S. Alahmari, Mohammed A. Alqahtani, Osama Abdulaziz, Isaiah Henry Ibeogu, Rongchang Wang, Chao Chen, Salem Baldi, Ibrahim Khalifa, Mohamed Abdin, Ahmed M. Saad, Mohamed T. El-Saadony

“…These findings position IgG NPs as a groundbreaking alternative for biomedical and pharmaceutical applications, offering enhanced stability, biocompatibility, and cost-effectiveness. Future research could explore their use in targeted drug delivery, immunomodulation, and functional food formulations, paving the way for innovative solutions in healthcare and biotechnology.…”
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To ensure safe care, we must embrace modern technologies: Utilizing smart rooms in nursing care in the emergency department by Reza Abdollahi, Samereh Eghtedar

“…One of the most significant obstacles is the high cost associated with developing and maintaining these systems, which requires robust infrastructure and seamless integration with existing hospital frameworks. …”
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The Health Effects of Gender-Based Violence in Conflict by Shadab Shahali

“…The loss of productivity and the cost of healthcare for survivors place additional burdens on already strained resources (World Bank,2024). …”
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