A Non-Vacuum Coating Process That Fully Achieves Technical Goals of Bipolar Plates via Synergistic Control of Multiple Layer-by-Layer Strategy by Qiaoling Liu, Xiaole Chen, Menghan Wu, Weihao Wang, Yinru Lin, Zilong Chen, Shuhan Yang, Yuhui Zheng, Qianming Wang

“…However, the above sputtering and evaporation ways require a high-vacuum condition, complicated experimental setups, higher costs, and an elevated temperature. Therefore, herein the achievement for uniform coatings over a large surface area has been realized by using a cost-effective strategy through a complete wet chemical process. …”
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Assessing the impact of diet formulation and age on targeted bacterial establishment in laboratory and mass-reared Mediterranean fruit fly using full-length 16S rRNA sequencing by Charles J. Mason, Rosalie C. Nelson, Mikinley Weaver, Tyler J. Simmonds, Scott M. Geib, Ikkei Shikano

“…This is a notable finding, as it suggests that full-length 16S rRNA approaches can have marked improvements for some taxa compared to fewer hypervariable regions at approximately the same cost. Our results provide new avenues for exploring and interrogating medfly-microbiome interactions.…”
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Establishment and Maintenance of a Digital Therapeutic Alliance in People Living With Negative Symptoms of Schizophrenia: Two Exploratory Single-Arm Studies by Cassandra Snipes, Cornelia Dorner‑Ciossek, Brendan D Hare, Olya Besedina, Tim Campellone, Mariya Petrova, Shaheen E Lakhan, Abhishek Pratap

“… BackgroundEvidence-based digital therapeutics represent a new treatment modality in mental health, potentially providing cost-efficient, accessible means of augmenting existing treatments for chronic mental illnesses. …”
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Inflammation mediated brain damage and cytokine expression in a maternally derived murine model for preterm hypoxic-ischemic encephalopathy by Tyler C. Hillman, Tyler C. Hillman, Braeden Jacobson, Kiara Piaggio Hurtado De Medoza, Marlene Lopez, Nicholas Iwakoshi, Christopher G. Wilson, Christopher G. Wilson, Christopher G. Wilson

“…We characterized a murine model for pHIE, which includes hypoxia and maternal factors as a cost-effective alternative to large animal models of HIE.MethodsWe injected pregnant mouse dams with LPS to stimulate an inflammatory response on embryonic days 15–16 (E15–E16), and whole cage hypoxia exposures occurred from postnatal days 3 to 9. …”
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Problems of management of patient biological waste in radionuclide diagnostics by L. A. Chipiga, S. A. Ryzhov, A. V. Vodovatov, I. A. Zvonova, A. V. Petryakova, A. A. Stanzhevsky, K. D. Kiselev, I. V. Glotova

“…Establishment of the requirement may lead to an increase the cost of the radionuclide diagnostic examinations, and to a decrease the accessibility of radionuclide diagnostic. …”
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Enhancing treatment outcomes after gynaecological cancer (ACUMEN): a randomised controlled exercise trial protocol by Vivian Chiu, Alexander Boytar, Brent Cunningham, Tina Skinner, Jane Turner, Debra Anderson, Asaduzzaman Khan, Tom Bailey, Janine Porter-Steele, Leonie Young, Haitham Tuffaha, Lewis Perrin, Andrea Garrett, Jeffrey Goh, Grace Rose, Briana Clifford, Sjaan Gomersall, Darren Korbie, Nicolas Constantin, Jackie Li, Alexandra Leigh McCarthy

“…The findings will help determine if the intervention is effective and sustainable, with a simultaneous cost-effectiveness analysis conducted to assess its value for money. …”
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medAL-suite: A software solution for creating and deploying complex clinical decision support algorithms by Ludovico Gennaro Cobuccio, Vincent Faivre, Rainer Tan, Alan Vonlanthen, Fenella Beynon, Emmanuel Barchichat, Alain Fresco, Quentin Girard, Sinan Ucak, Sylvain Schaufelberger, Ibrahim Evans Mtebene, Peter Agrea, Emmanuel Kalisa, Gillian A. Levine, Martin Norris, Sabine Renggli, Alix Miauton, Lisa Cleveley, Kristina Keitel, Julien Thabard, Valérie D’Acremont, Alexandra V. Kulinkina

“…Discussion The medAL-suite focused on democratized development, process-centric design, point-of-care utility, touch-screen interface, low cost, and low power consumption to contribute to sustainable digital systems in low-resource settings. …”
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Clinical correlation of SARS-CoV-2 wastewater passive sampling in long-term care facilities and wastewater treatment plants by William Strike, Alexus Rockward, Blazan Mijatovic, Ann Noble, Cullen Olsson, Soroosh Torabi, Mohammad Dehghan Banadaki, Reuben Adatorwovor, James Keck, Scott Berry

“…Wastewater-based epidemiology (WBE) is a promising tool for improving health outcomes through early detection and cost-effective pathogen surveillance. Long-term care facilities (LTCFs) serve and employ vulnerable populations that may particularly benefit from the use of WBE, but financial and technical costs associated with standard sampling methods limit the feasibility of WBE in the LTCF setting. …”
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Reproducibility of genetic risk factors identified for long COVID using combinatorial analysis across US and UK patient cohorts with diverse ancestries by J. Sardell, M. Pearson, K. Chocian, S. Das, K. Taylor, M. Strivens, R. Gupta, A. Rochlin, S. Gardner

“…In spite of this overwhelming disease prevalence, staggering cost, severe impact on patients’ lives and intense global research efforts, study of the disease has proved challenging due to its complexity. …”
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Factors predicting conversion from colon capsule endoscopy to conventional optical endoscopy—findings from the CESCAIL study by Ian Io Lei, Ioanna Parisi, Anirudh Bhandare, Francisco Porras Perez, Thomas Lee, Chander Shehkar, Mary McStay, Simon Anderson, Angus Watson, Abby Conlin, Rawya Badreldin, Kamran Malik, John Jacob, Andrew Dixon, Jeffrey Butterworth, Nicholas Parsons, Anastasios Koulaouzidis, Ramesh P. Arasaradnam, CESCAIL study group

“…Our findings would benefit from validation in different populations to develop a robust CCE Conversion Scoring System (CECS) and ultimately improve the cost-effectiveness.…”
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SaGP: identifying plant saline-alkali tolerance genes based on machine learning techniques by Baixue Qiao, Baixue Qiao, Baixue Qiao, Wentao Gao, Xudong Zhang, Xudong Zhang, Min Du, Min Du, Shuda Wang, Shuda Wang, Xuanrui Liu, Xuanrui Liu, Shaozi Pang, Shaozi Pang, Chunxue Yang, Jiang Wang, Jiang Wang, Yuming Zhao, Linan Xie, Linan Xie

“…Machine learning, in contrast, can accelerate the gene discovery process by learning from accumulated data, making it more efficient and cost-effective. However, despite their potential, existing machine-learning tools to mine stress-resistant genes in plants are scarce. …”
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An interoperable and standardized protocol for reporting systematic conservation planning projects by Martin Jung, Vanessa M. Adams, Diogo Alagador, Jorge G. Álvarez‐Romero, Miguel B. Araujo, Anni Arponen, Maria Beger, Jutta Beher, Silvia B. Carvalho, Sylvaine Giakoumi, Jeffrey O. Hanson, Virgilio Hermoso, Kerstin Jantke, Heini Kujala, Jennifer McGowan, Anna Metaxas, Louise O'Connor, Jose Salgado‐Rojas, Richard Schuster, Bob Smith, Piero Visconti

“…For example, they can help identify cost‐effective opportunities for expanding areas under conservation management to achieve high‐level policy goals such as those of the Global Biodiversity Framework. …”
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Design, Manufacture, and Performance Testing of a Water Hammer Pump with Five Different Air Chambers by Marco Fidel Romero Zárate, Héctor Flores-Breceda, Juan Arredondo-Valdez, Urbano Luna-Maldonado, Wilgince Apollon, Alejandro Isabel Luna-Maldonado

“…This study focused on optimizing the design and performance of low-cost water hammer pumps, which are powered by river currents and require minimal maintenance. …”
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Assessment of Long-Read Sequencing-Based Congenital Adrenal Hyperplasia Genotyping Assay for Newborns in Fujian, China by Xudong Wang, Xingxiu Lu, Faming Zheng, Kun Lin, Minjuan Liao, Yi Dong, Tiantian Chen, Ying He, Mei Lu, Jing Chen, Yanfang Li, Yulin Zhou

“…Therefore, LRS can provide comprehensive genotypes in approximately 1.5 days at a cost of less than $20 USD per sample, and effectively improve screening efficiency, reduce anxiety of parents during newborn screening (NBS), and shorten the time to referral of CAH patients (approximately 10 days). …”
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Diagnostic accuracy of SARS-CoV-2 antigen test in the pediatric population: A systematic review and meta-analysis by Cheng-Chieh Chen, Shih-Yen Chen, Shiuh-Bin Fang, Shou-Cheng Lu, Chyi-Huey Bai, Yuan-Hung Wang

“…The advantages of antigen tests, such as their relatively low cost and short turnaround time, can contribute to the prompt identification of infectious individuals. …”
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Development and validation of a recombinant Rap1-based lateral flow immunoassay for rapid serodiagnosis of bovine babesiosis in Kazakhstan by Kanatbek Mukantayev, Zhansaya Adish, Darkhan Kanayev, Laura Tokhtarova, Bisultan Abirbekov, Yergali Abduraimov, Aralbek Rsaliyev, Kanat Tursunov

“…Despite slightly lower sensitivity than ELISA, its simplicity, cost-effectiveness, and specificity support its use in large-scale epidemiological surveillance. …”
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A first large study of whole-exome sequencing (WES) in 489 patients with suspected rare genetic disorders at a tertiary centre in Malaysia by Lip Hen Moey, Go Hun Seo, Boon Eu Cheah, Wee Teik Keng, Hane Lee, Gaik Siew Ch’ng

“…Whole exome sequencing (WES) is a comprehensive test that can detect not only many of the same large deletions and duplications as CMA, but also detect other genetic variants that are detected by gene panels. Therefore, WES is cost effective and fast becoming a routine clinical test worldwide for patients suspected to have rare genetic disorders. …”
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The Impact of Delivery Methods on the Delivery Outcomes of Women with a Prolonged Second Stage and a Fetus in the Occipital Posterior Position by Jun Zhou, Shengyan Mao, Zhaoping Zheng, Chunxia Lin, Jia Tang, Jie Lin, Jie Ling, Lixi Yang, Zijuan Jiang, Dandan Wu

“…Results: The time of fetal head delivery, postpartum hemorrhage rate, hospitalization time, average hospitalization cost, and number of cases of postpartum infection in the group with a fetus in the occipital posterior position and low forceps-assisted delivery were significantly lower than those in the cesarean section group (p < 0.05). …”
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Perceived effectiveness and recommendations from a childbirth quality assurance and improvement programme in India’s private sector: a qualitative evaluation using the RE-AIM frame... by Katherine Semrau, Meghna Desai, Lauren Spigel, Somesh Kumar, Megan Marx Delaney, Lauren Bobanski, Suranjeen Pallipamula, Natalie Henrich, Tapas Sadasivan Nair, Hema Divakar, Rajat Chabba, Shweta Jindal, Gulnoza Usmanova, Sukanya Dutta, Aarushi Gupta, Sucheta Kinjawadekar, Priti Kumar, Priyanka Kumari, Prerna Mukharya, Hrishikesh Pai, Ameya Purandare, Pompy Sridhar

“…Barriers to joining included cost, unclear value and little motivation to improve practice. …”
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Technology Criteria for the Manufacturing of Rebamipide Film-coated Tablets by G. V. Trusov, B. V. Brovchenko, Z. M. Kozlova, I. I. Krasnyuk

“…Direct compression technology is a modern and cost-effective technology for solid dosage form drug manufacturing. …”
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