Enhancing skull base tumor management: the combination of 3D printing technology and endoscopic surgical techniques by Xiao Li, Peng Gao, Angsi Liu, Fuxing Zuo, Ke Hu, Yang Wang, Haiyan Li, Jianxin Kong, Xueji Li

“…The mean (standard deviation, SD) 3D printing time is 16.3 (5.54) hours, and the mean (SD) printing cost is 4,500 (1132.88) RMB, demonstrating the efficiency of this approach. …”
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Integrated system for screening tumor-specific TCRs, epitopes, and HLA subtypes using single-cell sequencing data by Yi Li, Weiguo Zhang, Xuelian Song, Xianyao Wang, Yanshu Ding, Chenfei Yin, Tianyuan Ren

“…For each TCR, only two pairs of oligonucleotides corresponding to the CDR3 regions of TCR-α and β chains needed to be synthesized, enabling the construction of a TCR library quickly in a cost-effective manner. Additionally, we engineered HLA-knockout HEK-293T cells as antigen-presenting cells to express patient-specific HLA-I and neoantigens, and a Jurkat NFAT-GFP reporter cell line for screening antigen-reactive TCRs. …”
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Development of the face-to-face component and recruitment strategy of a primary care digital social intervention for patients with asthma: Qualitative focus groups and interviews w... by Georgios Dimitrios Karampatakis, Samuel Kimber, Helen E. Wood, Chris J. Griffiths, Stephanie J. C. Taylor, Xiancheng Li, Bill Day, Jonathan Mant, Clare Relton, Jane S. Watson, Viv Marsh, Neil S. Coulson, Anna De Simoni

“…Future research should evaluate feasibility, effectiveness, and cost-effectiveness of such support.…”
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Comparative outcomes of unilateral biportal endoscopic lumbar intervertebral discectomy with and without annulus fibrosus suture in lumbar disc herniation: a retrospective analysis by Wei Zhou, Mohamed Lamin Bangura, Mohamed Lamin Bangura, Qianlong Gong, Rong Zhang, Teng Zeng, Qi Fei, Tadiwa Chiedza Chirima, Sy-Trung Tran, Yutian Qiu, Huasong Luo

“…Different variables, including clinical outcomes and estimated cost, were evaluated using IBM SPSS 27.0.1 with a p-value < 0.05 considered statistically significant.ResultsThe study identified disparities in clinical outcomes, such as reoperation problems, surgery durations, and projected costs between the two groups. …”
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Barriers and facilitators to patient utilization of noncommunicable disease services in primary healthcare facilities in Nepal: a qualitative study by Sushmita Mali, Elizabeth C. Rhodes, Chandani Singh Nakarmi, Soniya Shrestha, Aarati Dhakal, Alina Bharati, Anupama Bishwokarma, Asmita Adhikari, Bikram Poudel, Binuka Kulung Rai, Sangita Manandhar, Surakshya KC, Dinesh Timalsena, Sashi Silwal, Meghnath Dhimal, Phanindra Prasad Baral, Felix Teufel, Sanju Bhattarai, Donna Spiegelman, Archana Shrestha

“…Results From the perspectives of patients, key facilitators of service utilization encompassed free medicines, low-cost services, geographical and financial accessibility, less waiting time, positive interactions with health service providers, experiencing improvements in their health conditions, and support from family and peers. …”
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What are desirable biosecurity trainings for veterinary practitioners and farmers? by Anna Maria Iatrou, Blerta Mehmedi Kastrati, Rreze M. Gecaj, Georgios Batikas, Jarkko K. Niemi, Claude Saegerman, Alberto Oscar Allepuz, Wiebke Jansen, Nancy De Briyne, Daniele De Meneghi, Murat Yılmaz, Evelien Biebaut, Ramazan Yildiz, Marco De Nardi, Carla Correia-Gomes, Tarmo Niine

“…Therefore, recommendations focus on developing species-specific, flexible modules that embed communication and cost-benefit elements, provide micro-learning units for time-constrained farmers, and operate within a tiered certification framework linked to continuing professional development. …”
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Mathematical modeling, drying kinetics, and economic analysis of a hybrid photovoltaic thermal solar dryer for henna leaves by Abdallah Elshawadfy Elwakeel, Awad Ali Tayoush Oraiath, Tarek Hussien M. Ghanem, Ahmed Elbeltagi, Ali Salem, Ahmed Z. Dewidar, Abdelaziz M. Okasha, Abadeer Habib, Tamer M. El-Messery, Moustapha Eid Moustapha, Khaled A. Metwally

“…On the other hand, the economic analysis revealed that the DDSD has the potential to generate substantial cost savings, amounting to 3,348 USD per year. Additionally, the payback period was calculated to be 0.077 years (less than one month), demonstrating the system’s rapid return on investment and economic viability.…”
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Methodology for generating chorioallantoic membrane patient-derived xenograft (CAM-PDX) models of pleural mesothelioma and performing preclinical imaging for the translation of can... by Judy M Coulson, Joseph J Sacco, Michael Shackcloth, Alexander Haragan, Doris M Rassl, Harish Poptani, Anne Herrmann, Liam Shaw, Sarah Barnett, Jan Schulze

“…Fertilized hens’ eggs provide a rapid and cost-effective alternative to murine models of pleural mesothelioma which are commonly used in preclinical studies, with chorioallantoic membrane (CAM) xenografts being a partial replacement for mouse flank xenografts. …”
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varVAMP: degenerate primer design for tiled full genome sequencing and qPCR by Jonas Fuchs, Johanna Kleine, Mathias Schemmerer, Julian Kreibich, Wolfgang Maier, Namuun Battur, Thomas Krannich, Somayyeh Sedaghatjoo, Lena Jaki, Anastasija Maks, Christina Boehm, Carina Wilhelm, Jessica Schulze, Christin Mache, Elischa Berger, Jessica Panajotov, Lisa Arnold, Björn Grüning, Markus Bauswein, Sindy Böttcher, Reimar Johne, Jürgen Wenzel, Martin Hölzer, Marcus Panning

“…Abstract Time- and cost-saving surveillance of viral pathogens is achieved by tiled sequencing in which a viral genome is amplified in overlapping PCR amplicons and qPCR. …”
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Precise Performance Analysis of Dual-Hop Mixed RF/Unified-FSO DF Relaying With Heterodyne Detection and Two IM-DD Channel Models by Omer Mahmoud Salih Al-Ebraheemy, Anas M. Salhab, Anas Chaaban, Salam A. Zummo, Mohamed-Slim Alouini

“…Moreover, this is the first time that not only the (IM-DD input-independent) but also the (IM-DD cost-dependent) additive white Gaussian noise (AWGN) channel is considered in such system analyses. …”
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Penerapan Metode Association Rule Mining untuk Asosiasi Ulasan Terhadap Aspek Tempat Wisata Jawa Timur Park 3 by Aisyatul Maulidah, Fitra A. Bachtiar

“…These aspects include road access, cost, cleanliness, satisfaction, hustle, service, security, and technology. …”
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Participation, knowledge, and attitudes toward cervical cancer screening among migrant Burmese women on China-Myanmar border: a cross-sectional study by Jiawei Hu, Honghao Wang, Shuang Zhao, Liuye Huang, Xiaoqing Chen, Xuelian Zhao, Yong Zhang, Fanghui Zhao

“…The most common barrier to therapy was unaffordable cost. Conclusions: Migrant Burmese women in Mangshi had suboptimal screening participation and inadequate cervical cancer knowledge. …”
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A prospective study of vaginal topical pretreatment of compound sea-buckthorn oil suppository in postmenopausal women prior to colposcopy by Yi Yu, Qing Li, Yuankui Cao, Hongwei Zhang, Yu Song, Qing Cong, Long Sui, Limei Chen

“…Compared to estrogen ointment, compound sea-buckthorn oil suppositories are most cost-effective and have fewer side effects and can be applied in clinical practice.…”
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The Development of a Phytopathogenic Fungi Control Trial: Aspergillus flavus and Aspergillus niger Infection in Jojoba Tissue Culture as a Model by Nawal Abd El-Baky, Raoufa Ahmed Abdel Rahman, Mona Mohammed Sharaf, Amro Abd Al Fattah Amara

“…Fungal pathogens that infect plants critically affect cost effectiveness, quality, and quantity of their production. …”
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Synthesis of Cu4O3 nanoparticles using pumpkin seed extract: Optimization, antimicrobial, and cytotoxicity studies by Khan Azhar U., Khan Azmat Ali, Malik Nazia, Her Jun, Gupta Mona, Panda Subhranshu, Imtiyaz Khalid, Alam Rizvi Mohammed Moshahid, Mushtaque Mohammed, Bansod Sudhakar M., Mohammad Masita, Kim Min, Pyo Kyungsoo, Alam Mahboob

“…Unlike conventional chemical methods, this eco-friendly route enables rapid, cost-effective NP production with minimal environmental impact. …”
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Clinical utility of the FilmArray® meningitis/encephalitis panel in children with suspected central nervous system infection in a low-resource setting – a prospective study in Sout... by Reza Rasti, Elias Kumbakumba, Deborah Nanjebe, Phuthumani Mlotshwa, Milly Nassejje, John Mzee, Stephen Businge, Gilbert Akankwasa, Dan Nyehangane, Jesper Gantelius, Yap Boum, Andreas Mårtensson, Juliet Mwanga-Amumpaire, Tobias Alfvén, Giulia Gaudenzi

“…More epidemiologically customized pathogen panels may increase FA-ME utility locally, although its use in similar settings would require major cost reductions. Trial registration The trial was registered with clinicaltrials.gov (NCT03900091) in March 2019, and its protocol was published in November 2020.…”
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High-value utilization of agricultural residues based on component characteristics: Potentiality and challenges by Rui Xu, Jingwen Chen, Nina Yan, Bingqian Xu, Zhichao Lou, Lei Xu

“…In addition, this review directly addresses current research challenges, such as technical limitations, cost-benefit analysis, and standardization of environmental impact assessment. …”
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Preferences for HIV pre‐exposure prophylaxis among men who have sex with men and trans women in 15 countries and territories in Asia and Australia: a discrete choice experiment by Warittha Tieosapjaroen, Benjamin R. Bavinton, Heather‐Marie A. Schmidt, Curtis Chan, Kim E. Green, Nittaya Phanuphak, Midnight Poonkasetwattana, Nicky S. Suwandi, Doug Fraser, Hua Boonyapisomparn, Michael Cassell, Lei Zhang, Weiming Tang, Jason J. Ong

“…Results Among 21,943 participants included in the MSM survey and 1522 in the TGW survey, the mean age was 31.7 (±9.5) years and 28.1 (±7.0) years, respectively. Cost emerged as the primary driver of PrEP use for MSM and TGW across countries, followed by the type of PrEP. …”
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A structured lifestyle intervention to reduce cardiometabolic risk factors in individuals with obsessive–compulsive disorder: feasibility trial by Anna Holmberg, Matthias Lidin, Dante Lenninger, Sofia Asplund, Catharina Lavebratt, Christian Rück, Lina Martinsson, David Mataix-Cols, Lorena Fernández de la Cruz

“…Fully powered randomised controlled trials are needed to evaluate its efficacy and cost-effectiveness. …”
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Interface engineered, high photo-response of self-powered photodetector and solar cell based on PEDOT:PSS-silicon hybrid heterojunction by Urvashi Punia, Pukhraj Prajapat, Ruchi K. Sharma, Jayant, Govind Gupta, Sanjay K. Srivastava

“…However, optoelectronic applications of organic-inorganic hybrid photodetectors have gained the significant attention of the scientific community in the recent years due to their higher performance and lower fabrication cost. Here, the hybrid heterojunction model based on silicon (Si) and a conjugate organic polymer, poly (3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) is explored as self-biased, broadband and high-speed photodetectors, which are least explored when compared to its solar cell counterparts. …”
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