Exploring social impairment in those with opioid use disorder: linking impulsivity, childhood trauma, and the prefrontal cortex by Thais Costa Macedo de Arruda, Laura Sinko, Paul Regier, Altona Tufanoglu, Adrian Curtin, Anne M. Teitelman, Hasan Ayaz, Peter F. Cronholm, Anna Rose Childress

“…Functional near infrared spectroscopy (fNIRS), a modern, portable, wearable and low-cost neuroimaging technology, was used to measure prefrontal cortex activity during a behavioral inhibition task (Go/No-Go task). …”
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Core-Shell Magnetic Nanocarriers: Fe3O4-Hydroxyapatite/Polysuccinimide Hybrids for Enhanced Oral Bioavailability of Fluorouracil by Zhang W, Wang Q, Zhai F, Fan X, Meng F, Shen G, Zhu Y, Cao J, Yu F

“…The system offers uniform particle size, a simple preparation process, and a cost-effective method for targeted drug delivery. …”
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Exemplar Hospital Initiation Trial to Enhance Treatment Engagement (EXHIT ENTRE): protocol for CTN-0098 an open-label randomized comparative effectiveness trial of extended-release... by Gavin Bart, Kelly S. Barth, Paulette Baukol, Eva Enns, Udi E. Ghitza, Jacklyn Harris, Eve Jelstrom, Jane M. Liebschutz, Kara M. Magane, Delia Voronca, Zoe M. Weinstein, P. Todd Korthuis

“…Safety, secondary, and exploratory outcomes include: adverse events, MOUD engagement on days 90 and 180, opioid positive urine drug tests, self-reported drug use, hospital readmissions and emergency department visits, use of non-opioid drugs, fatal and non-fatal opioid overdose, all-cause mortality, quality of life, and cost-effectiveness. Data are analyzed by intention-to-treat, with pre-planned per-protocol and other secondary analyses that examine gender as an effect modifier, differences between groups, and impact of missingness. …”
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Applying the major system change framework to evaluate implementation of rapid healthcare system change: a case study of COVID-19 remote home monitoring services by Holly Walton, Nadia Crellin, Ian Litchfield, Chris Sherlaw-Johnson, Theo Georghiou, Efthalia Massou, Manbinder Sidhu, Sonila M. Tomini, Lauren Herlitz, Jo Ellins, Pei Li Ng, Naomi J. Fulop

“…Service providers completed cost surveys. Aggregated and patient-level national datasets were used to explore enrolment, service use and clinical outcomes. …”
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Diseño óptimo de redes hidráulicas bajo criterios múltiples. // Optimal design of water supply nets by means of multiple criteria optimization. by J. R. Hechavarría Hernández, J. Arzola Ruiz, A. Cordovés García, A. M. Lastre Aleaga

“…The designing<br />process must take into account two of the most important problems of the world: energy and cost.<br />Universal literature does not provide with methodological solutions to determine sufficiently rational solutions to the<br />problem of designing closed hydraulic networks, at least at the level of considering the generally accepted criteria as<br />important to decide on the network's design, including the determination of the most rational trajectory of the network and<br />the subjective aspects.…”
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Efficacy of Chinese traditional quadruple single pill combination versus valsartan/hydrochlorothiazide for the treatment of hypertension (COSPQ-BP): study protocol for randomised c... by Kai Liu, Yu Yan, Xin Zhang, Yanan Li, Yuanyuan Yao, Lu Liu, Runyu Ye, Si Wang, Xiangyu Yang, Xiaoping Chen, Shanshan Jia, Qingtao Meng, Xianghao Zuo

“…It is widely employed in primary medical institutions and has favourable efficacy, tolerability and cost-effectiveness.Methods and analysis The COSPQ-BP trial is a 12-week prospective randomised controlled trial to enrol 1332 patients with primary mild-to-moderate hypertension. …”
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Implementation of a primary-tertiary shared care model to improve the detection of familial hypercholesterolaemia (FH): a mixed methods pre-post implementation study protocol by David Sullivan, Charlotte Mary Hespe, Mitchell N Sarkies, Andrew Partington, Elizabeth Robertson, Gabrielle Fleming, Stephen Li, Karen Birkenhead, Claire Trumble, Catherine Spinks, Shubha Srinivasan, Luke Elias, Madeline Calder, Ronald Trent

“…Implementation of the shared care model will be evaluated using a modification of the implementation outcome taxonomy and will focus on the acceptability, evidence of delivery, appropriateness, feasibility, fidelity, implementation cost and timely initiation of the intervention. Quantitative pre-post and qualitative semistructured interview data will be collected. …”
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Effect of a pay-it-forward strategy on reducing HPV vaccine delay and increasing uptake among 15- to 18-year-old girls in China: A randomized controlled trial. by Jing Li, Yifan Li, Chuanyu Qin, Yu He, Haidong Lu, Yewei Xie, Jason J Ong, Yajiao Lu, Ying Yang, Fan Yang, Heng Du, Wenfeng Gong, Fei Zou, Heidi J Larson, Mark Jit, Leesa Lin, Jennifer S Smith, Elvin H Geng, Dong Xu, Weiming Tang, Shenglan Tang, Joseph D Tucker, Dan Wu

“…Among 55 girls in the pay-it-forward arm who received the vaccination, 37 (67.3%) wrote a postcard message, and 39 (70.9%) of their caregivers donated to support future girls. The financial cost per person vaccinated was $294 in the control arm and $230 in the pay-it-forward arm. …”
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Impact of mineral nutrition and biopriming on crop performance, energetics, and the carbon footprint in rainfed castor bean (Ricinus communis L.) by Revappa Mohan Kumar, Yamanura Madival, Mahantesh Basangouda Nagangoudar, Nagesha Narayanappa, Gopalaswamy Ranganath, Sugganahalli Channappa Ranganatha, Venkatesh Paramesh, Dinesh Jinger

“…The highest gross returns (₹ 80,412 ha-1), net returns (₹ 50,511 ha-1) and benefit-cost ratios (2.68) were also found higher with RRF. …”
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Neuromuscular Electrical Stimulation to Maximize Hip Abductor Strength and Reduce Fall Risk in Older Veterans: Protocol for a Randomized Controlled Trial by Ben Friedman, Brock A Beamer, Jeffrey Beans, Vicki Gray, Gad Alon, Alice Ryan, Leslie I Katzel, John D Sorkin, Odessa Addison

“…If successful, NMES combined with hip abductor strengthening and balance training could provide a low-cost, scalable solution to reduce falls, improve balance and mobility, and decrease health care costs related to falls in older adults. …”
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Short-term outcomes of faricimab and aflibercept 8 mg in diabetic macular edema by Carlo Maccauro, Yanny Jimenez Perez, Piergiorgio Neri, Ibraheem El Ghrably, Haytham I Salti, Francesco Pichi

“…These findings highlight the importance of individualized treatment considerations, such as cost, accessibility, and patient preference. Further prospective studies are needed to validate these results and assess long-term treatment durability across different regimens.…”
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Filling knowledge gaps: A methodological approach for the rapid investigation of species with restricted populations by André Cesar Furlaneto Sampaio, Pablo Melo Hoffmann, Elivelton Marcos Gurski, Ollyver Rech Bizarro, Santiago José Elías Velazco, Marcos Bergmann Carlucci, Marília Borgo, Mayara Monteiro Ferreira, Alessandro Camargo Angelo, Christopher Thomas Blum

“…To address this issue, we developed the Multi-Scale Habitat and Population Rapid Assessment (MHPR) methodology, integrating widely tested, low-cost, and rapid-application technologies to assess distribution, demography, and population decline risks in species with restricted populations. …”
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Coating technology on mortar surface for extending service life of on-site building construction by Jumrus Nidchamon, Thapinta Monwipa, Chaiwong Patcharaporn, Pantawan Arisara, Kumpika Tewasin, Thongpan Winai, Jhuntama Niwat, Kantarak Ekkapong, Sroila Wattikon, Rianyoi Rattiyakorn, Singjai Pisith, Thongsuwan Wiradej

“…Thus, the fabrication of superhydrophobic mortar surface offers a novel, alternative approach that is simple, efficient, cost-effective and provides multifunction protection surface to increase the service life of on-site building construction with enhanced mechanical durability and anti-corrosion properties.…”
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Deep Learning Python-Based Time-Series Model for Oil Palm Yield Prediction by Yuhao Ang, Helmi Zulhaidi Mohd Shafri, Yang Ping Lee, Shahrul Azman Bakar, Haryati Abidin, Mohd Umar Ubaydah Mohd Junaidi, Hwee San Lim, Rosni Abdullah, Yusri Yusup, Syahidah Akmal Muhammad, Teh Sin Yin

“…The time-series predictive models developed in this study can assist plantation management in making informed decisions concerning yield forecasting, which is crucial for effective management of inputs, ultimately leading to cost optimization and enhanced sustainability in oil palm cultivation.…”
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Performance Enhancement of Lead-Free CsSnI₃ Perovskite Solar Cell: Design and Simulation With Different Electron Transport Layers by Md. Ferdous Wahid, Md. Shahriar Rahman, Nowshad Ahmed, Abdullah Al Mamun, Md. Nuralam Howlader, Tarpan Paul, Md. Motiur Rahman Tareq, Md. Sazedur Rahman, Md. Mizanur Rahman

“…CsSnI3 is a promising lead-free material that shows potential as a substitute for lead-based material in the development of ecologically benign perovskite solar cells (PSCs) due to its low cost, high efficiency, and excellent thermal stability. …”
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CONCEPTUAL FEATURES OF OCCLUSAL BALANCE IN THE DEVELOPMENT AND PATHOLOGY OF LOCALIZED AND GENERALIZED DISEASES OF PARODONTAL TISSUES IN PATIENTS WITH PARTIAL TOOTH LOSS DURING ORTH... by Yu.O. Kinash, L.V. Kinash

“…Unfortunately, modern technologies are not available to all patients and medical institutions of health care of Ukraine due to their high cost. Consequently, a significant number of orthopedic restorations are manufactured in commercial technical laboratories or manually by dental technicians in municipal health care facilities. …”
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Enhancing yield and quality: research and practice of agro-forest waste for Lentinus edodes (shiitake mushroom) cultivation by Hongyan Xu, Hongyan Xu, Guocai Han, Yanyan Li, Qing Meng, Qing Meng, Yang Zhang, Yayi Wang, Songling Li

“…Consequently, the utilization of agroforestry waste serves as an effective strategy not only for environmental protection and cost reduction during mushroom production but also for enhancing the nutritional value of shiitake mushrooms. …”
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Development of Real-Time and Lateral Flow Dipstick Recombinase Polymerase Amplification Assays for the Rapid Field Diagnosis of MGF-505R Gene-Deleted Mutants of African Swine Fever... by Jizhou Lv, Junhua Deng, Yu Lin, Dongjie Chen, Xiangfen Yuan, Fang Wei, Caixia Wang, Xiaolin Xu, Shaoqiang Wu

“…These assays offer a simple, cost-effective, rapid, and sensitive method for on-site identification of ASFV MGF-505R gene-deleted mutants. …”
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Impact of a mobile health intervention on health management among children with phenylketonuria based on a multi-theory model of the behavior change wheel theory and family health... by Jie Wang, Sihan Yang, Jing Wang, Bo Zhu, Yan Wang, Lirong Zhao, Wenli Wang, Ge Li, Fei Wang, Fei Wang, Xiaohua Wang

“…Mobile health (mHealth) interventions, as an emerging health management approach, offer personalized, low-cost, and highly accessible solutions. This study aims to develop and evaluate an mHealth intervention model based on the Behavior Change Wheel (BCW) theory and family health theory to improve health management for children with PKU.MethodsThis single-center, single-blind randomized controlled trial will be conducted at the Inner Mongolia Maternity and Child Health Care Hospital in China from March to September 2025. …”
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Ni3S2@MoO3@Co3O4@AMO/NF core–shell heterostructure for high performance alkaline overall water splitting by Jiabang Liang, Yu Liu, Zegao Wang, Yifan Jia, Zhao Ding, Liangjuan Gao

“…Abstract The urgent need for bi-functional high-performance non-noble metal-based catalysts for water splitting requires the integration of both oxygen evolution reaction (OER) and hydrogen evolution reaction (HER) together, which not only increases the energy efficiency but also reduces fabrication cost. However, most non-noble metal-based catalysts for OER are not stable under alkaline conditions, while HER shows poor kinetic performance under alkaline conditions, which prevents the water splitting from scale-up applications. …”
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