Chronic disease medications accessibility among Sudanese patients during war by Thoraya Salah Murtada Sidahmed, Al-Romaysa M. Osman Khalafalla El-Haj, Hiba Salah Abdelgadir, Afra K. Ahmed, Asjad Elias Sidieg Mohammed, Abdelfatah Abdelelah El Zain Hassan, Ebaa Ismat Mahmoud Ahmed, Hiba Algaali Altayeb Babikir, Khalid Mukhtar Awad Hamza, Alaa Hamid Yousif Ahmed, Mojtaba Majdy Elfakey Omer, Shahad Yahya Awadelkarim Elbadawi, Logaine Tarig Abdelwahab Mohammed, Rawan Ali Ahmed Mohamed Ahmed, Hind Elmukashfi ShamsEldin Elobied, Hind Salah Abdelgadir, Ruba Ahmed Osman Mohamed, Hala Hashim Salim Hamza, Omnia Yousif Abdalmalik Alfaki, Arwa Yagoub Elmadani Ibrahim, Rawan Izzeldin Babiker Farah, Abeer Hussien Musa Mohamed, Amaal Izzeldin Ahmed Altamar, Lana Awad Jahallah Hassab Alrasoul, Ali Mohamedahmed Ali Mohamed, Mohamedelamin Abdelgayoum Khalifa, Tarig Siddig Abdelgader Mohieldin, Soujod Emad Elden Mohamed Elamen

“…Reported barriers to accessing medications included high costs (34.0%), low income (26.7%), insecurity (42.5%), and displacement-related challenges (29.9%). …”
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Maximising Embedded Pharmacists in AGed CAre Medication Advisory Committees (MEGA-MAC): protocol for implementing Australia’s new guiding principles for medication management in re... by Amanda J. Cross, Brooke Blakeley, Kate Laver, Terry P. Haines, Sarah N. Hilmer, Atish Manek, Alexandra Bennett, Angelita Martini, Lyntara Quirke, Mary Ann Kulh, Sara L. Whittaker, Dayna R. Cenin, Anthony Hobbs, Joanne Money, Karina Rieniets, Kris Salisbury, Alene Sze Jing Yong, J. Simon Bell

“…A net benefit analysis will be conducted to examine the relative costs and benefits of implementing the intervention. …”
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Prevalence of chronic wounds in hospitalised patients in Catalonia, Spain: a multicentre cross-sectional descriptive observational study by Jordi Adamuz, Maribel González-Samartino, Marta Tapia-Pérez, Trinidad Castro-Navarro, Maria-Eulàlia Juvé-Udina, Marta Romero-García, María Magdalena López-Jiménez, Carmen Berbis-Morelló, Mònica Pons-Prats, Esperanza Zuriguel Pérez

“…Understanding these characteristics within the inpatient setting can support improved follow-up, inform care strategies, enhance quality and safety and reduce associated healthcare costs. This study aimed to determine the prevalence and the sociodemographic profile of adult inpatients with chronic wounds admitted to the eight hospitals of the Catalan Institute of Health between 2016 and 2020.Methods A descriptive, observational, cross-sectional and retrospective multicentre study was conducted using routinely collected clinical data from 1 January 2016 to 31 December 2020. …”
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DeintensiF: Standard versus individualized deintensified follow-up after curative treatment in head and neck cancer: protocol of a randomized pilot study by M. Mueller, M. Visini, S. A. Mueller, T. Stadler, G. P. Rajan, G. B. Morand, S.-L. Hool, D. H. Schanne, P. Balermpas, A. Limacher, S. Chan, S. Trelle, O. Elicin, R. Giger

“…However, routine follow-up involves social and financial burdens, including frequent imaging associated with radiation exposure and costs. Currently, there is no consensus on the follow-up strategy after HNC treatment, and no conclusive evidence shows a survival advantage for routine follow-up over symptom-driven self-referrals. …”
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Low-activity [18F]-somatostatin receptor (SSTR) imaging using [18F]SiTATE on a long axial field-of-view PET/CT scanner by Nils F. Trautwein, Eduardo Calderón, Pia M. Linder, Gerald Reischl, Philippe Driessen, Wenhong Lan, Andreas S. Brendlin, Thorben Groß, Helmut Dittmann, Martina Hinterleitner, Christian la Fougère, Fabian P. Schmidt, Lena S. Kiefer

“…Abstract Purpose 18F-labelled somatostatin receptor tracers have recently gained popularity due to their better spatial resolution, longer half-life and lower costs compared to 68Ga-labeled tracers. The aim of this study was to evaluate the impact and limitations of reduced administered activities of [18F]SiTATE on image quality, lesion detectability and quantitative PET parameters in a long axial field-of-view (LAFOV) PET/CT scanner. …”
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Clinical effect analysis of unilateral percutaneous vertebral cement distribution in the repair of osteoporotic thoracolumbar vertebral compression fractures by Liu Yuntao, Abuduwupuer Haibier, Aiben Kayierhan, Ma Liang, Yimuran Abudukelimu, Alimujiang Aximu, Tuerhongjiang Abudurexiti, Meng Xiangyu

“…The basic information of patients, surgery-related indicators including operation time, total hospitalization costs, postoperative hospitalization time, cement injection volume, visual analog scale (VAS) for back pain, Oswestry Disability Index (ODI) for back pain, vertebral height restoration rate, local kyphotic angle of the vertebra, and incidence of re-fracture of injured and adjacent vertebrae were compared between the two groups, and the follow-up results of all patients were recorded. …”
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Total neoadjuvant therapy based on short-course radiotherapy versus standard long-course chemoradiotherapy for locally advanced rectal cancer: a systematic review and meta-analysis... by Wenji Pu, Wenji Pu, Wenji Pu, Wenqi Chen, Haiman Jing, Jishi Li, Yong Jiang, Shasha Li, Weijie Wen, Zhiyuan Xu, Jing Jin

“…Moreover, survival outcomes, distant recurrence rate, and surgical indicators were comparable between the two groups.ConclusionFor LARC patients, the SCRT/CCT regimen not only has a higher pCR rate, equivalent OS, and comparable additional indicators versus standard LCCRT but also shortens the treatment time, costs less, and improves patients’ adherence to the innovative anti-tumor therapy; hence, with the concept of acute toxicity control, it could be further widely and safely utilized, especially in resource-limited settings.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/, identifier CRD42024600180.…”
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A case study of the co-creation of the PrEP-SIC: a roadmap to support introduction of pre-exposure prophylaxis into new settings by Kathrine Meyers, Benjamin Lane, Jason Zucker, Yumeng Wu, Caroline Carnevale, Helen Burnside, Sarah Rowan, Eric Mayes, Gilianne Narcisse-Cempini, Melanie A. Gold, Lisa Saldana, Sarit A. Golub

“…Results Five themes emerged about the accuracy of the PrEP-SIC to capture real world implementation processes: (1) Some PrEP-SIC activities, such as generating a costing plan, are not reflected in real-world implementation; (2) Sites do not define sustainment as achieving a set of quantitative program goals, but rather as being able to continue a program through staffing turnovers and shortages; (3) Written protocols and reviewing clinic data for program improvement were identified as two key factors that differentiate sites that reached sustainment from sites that did not; (4) The PrEP-SIC is assessed as somewhat useful to guide introduction of PrEP, but pairing the tool with technical assistance or coaching would optimize its utility; (5) Implementation is cyclical and recursive and pre-implementation activities may need to be revisited over time to ensure sustainment. …”
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Quantifying economic risks to dairy farms from volcanic hazards in Taranaki, Aotearoa / New Zealand by N. J. McDonald, L. Dowling, E. P. Harvey, A. M. Weir, A. M. Weir, M. S. Bebbington, N. Bui, C. Magill, H. M. Craig, G. W. McDonald, J. J. Monge, S. J. Cronin, T. M. Wilson, D. Walker

“…To do this, we developed a dynamic, multi-event farm system model of response and recovery, which takes in hazard intensity metrics from a series of volcanic events and generates the resulting annualised revenues, expenditures, and recovery costs through time. The model is formulated in a generalised way such that it can be used for various other hazard types and agricultural land uses. …”
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Epidemiology and risk factors of healthcare-associated urinary tract infections: a prospective study in a Tunisian tertiary hospital by Hela Ghali, Omar Khalil Ben Saad, Sana Bhiri, Salma Balhi, Farah Azouzi, Amani Maatouk, Sameh Boughattas, Saoussen Layouni, Jihed Anoun, Sofien Benzarti, Emna Trabelsi, Zeineb Mrizak, Maha Brahim, Arwa Nafetti, Aroua Kamel, Fatima E. Khouya, Sofien Aidani, Yosr Boussoukaya, Mohamed Ben Rejeb, AbdelHalim Trabelsi, Houyem S. Latiri, Asma Ben Cheikh

“…Abstract Healthcare-associated urinary tract infections (HAUTIs) represent a significant challenge to healthcare systems worldwide, contributing to patient morbidity, mortality, and increased healthcare costs. Understanding the epidemiology and risk factors associated with HAUTIs is crucial for implementing targeted prevention strategies and optimizing patient care. …”
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Socio-economic contextual determinants and behavioral changes during pregnancy: evidence from the "MAMI-MED" cohort by Francesca Bitonti, Angelo Mazza, Martina Barchitta, Andrea Maugeri, Roberta Magnano San Lio, Giuliana Favara, Claudia La Mastra, Maria Clara La Rosa, Fabiola Galvani, Elisa Pappalardo, Carla Ettore, Giuseppe Ettore, Federico Mertoli, Carmela Elita Schillaci, Antonella Agodi

“…Geocoding techniques were employed to link individual-level data to selected contextual variables related to education, income, unemployment, and housing costs in the participants' residential areas. Mann–Whitney test, Kruskal–Wallis tests, logistic regressions and mixtures of regressions models with concomitant variables are implemented 1) to investigate the associations between contextual covariates and individual responses, 2) to assess the presence of latent sub-groups of the population reacting differently to the same contextual factors. …”
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Urban Tree Canopy Mapping and Analysis Using Iterative Annotation Method and Deep Learning: A Case Study in Beijing by Yulong Ding, Ximin Cui, Zhengchao Chen, Zeqing Wang, Debao Yuan, Xiang Meng, Xuan Yang, Yue Xu, Xiangyu Tian

“…Deep learning models typically require large amounts of labeled data for training, but manually annotating pixel-level labels is time-consuming and costly. To address this, we propose an iterative method based on intersection over union (IoU), integrating multiscale segmentation and nearest-neighbor classification algorithms. …”
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Age and sex specific thresholds for risk stratification of cardiovascular disease and clinical decision making: prospective open cohort study by Matthew Sperrin, Angela M Wood, Lois Kim, Zhe Xu, Emanuele Di Angelantonio, Stephen Kaptoge, Juliet Usher-Smith, Matthew Arnold, Lisa Pennells, Ryan Chung

“…Such gains should be weighed against the costs of treating more younger people with statins for longer.…”
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Integrating anamnestic and lifestyle data with sphingolipid levels for risk-based prostate cancer screening by Caterina Peraldo-Neia, Paola Ostano, Melissa Savioli, Maurizia Mello-Grand, Ilaria Gregnanin, Francesca Guana, Francesca Crivelli, Francesco Montagnani, Michele Dei-Cas, Rita Paroni, Antonella Sinopoli, Francesco Ferranti, Nicolò Testino, Marco Oderda, Andrea Zitella, Chiara Fiameni, Amedeo Gagliardi, Alessio Naccarati, Luca Clivio, Paolo Gontero, Stefano Zaramella, Giovanna Chiorino

“…Conclusions Circulating sphingolipids are promising biomarkers that, when combined with PSA, anamnestic, and lifestyle data, may enhance PCa screening precision and reduce the need for invasive, costly examinations.…”
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Comparative clinical characteristics among different age group of adult COVID‐19 patients: A multicenter study by Wei Cheng †, Yating Peng †, Aiyuan Zhou, Ling Lin, Xin Liao, Dingding Deng, Peng Huang, Wenlong Liu, Mingyan Jiang, Xudong Xiang, Qingcui Shuang, Shan Cai, Ping Chen, Xucai Liao

“…Abstract Background Coronavirus disease (COVID‐19) is a global infectious disease with a large burden of illness and high health care costs. This study aimed to compare clinical features among adult COVID‐19 patients in different age groups. …”
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A new gridded offshore wind profile product for US coasts using machine learning and satellite observations by J. Frech, J. Frech, K. Saha, K. Saha, P. D. Lavin, P. D. Lavin, H.-M. Zhang, J. Reagan, B. Fung

“…In situ wind profiles have sparse geospatial coverage and are costly to obtain en masse, whereas satellite-derived 10 m wind speeds have vast coverage at high resolution. …”
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Systematic bias between blinded independent central review and local assessment: literature review and analyses of 76 phase III randomised controlled trials in 45 688 patients with... by Jianrong Zhang, Yu Huang, Hengrui Liang, Wenhua Liang, Jianxing He, Yiyin Zhang, Jiaxi He, Jieyu Wu, Long Jiang, Shiyan Tang, Qihua He, Lindsey Tristine Hamblin, Zhiheng Xu, Yaoqi Chen, Difei Chen, Xinyu Wang, Kexin Deng, Shuhan Jiang, Jiaqing Zhou, Jiaxuan Xu, Xuanzuo Chen

“…Blinded independent central review is usually used as a supplemental or monitor to local assessment but is costly. The aim of this study is to investigate whether systematic bias existed in RCTs by comparing the treatment effects of efficacy endpoints between central and local assessments.Design Literature review, pooling analysis and correlation analysis.Data sources PubMed, from 1 January 2010 to 30 June 2017.Eligibility criteria for selecting studies Eligible articles are phase III RCTs comparing anticancer agents for advanced solid tumours. …”
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Awareness, attendance, and attitudes toward cervical cancer screening among HIV-positive Chinese women in Yunnan province: a cross-sectional study by Jiawei Hu, Rufei Duan, Hongyun Zhang, Xuelian Zhao, Aihui Wu, Le Li, Fanghui Zhao, Yong Zhang

“…The main facilitators to attending cervical cancer screening were health promotion activity and well-organized programs, while the main barriers were high costs of the service and inadequate awareness. Conclusions Although most HIV-positive women attending a large ART clinic in Yunnan were aware of cervical cancer screening, the up-to-date attendance was low. …”
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Antimicrobial-Resistance and Virulence-Associated Genes of <i>Pasteurella multocida</i> and <i>Mannheimia haemolytica</i> Isolated from Polish Dairy Calves with Symptoms of Bovine... by Agnieszka Lachowicz-Wolak, Aleksandra Chmielina, Iwona Przychodniak, Magdalena Karwańska, Magdalena Siedlecka, Małgorzata Klimowicz-Bodys, Kamil Dyba, Krzysztof Rypuła

“…Bovine respiratory disease causes significant economic losses in cattle farming due to mortality, treatment costs, and reduced productivity. It involves viral and bacterial infections, with <i>Pasteurella multocida</i> and <i>Mannheimia haemolytica</i> key bacterial pathogens. …”
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Acceptability of intermittent preventive treatment of malaria in pregnancy with sulfadoxine-pyrimethamine plus dihydroartemisinin-piperaquine in Papua New Guinea: a qualitative stu... by Elvin Lufele, Sophie Pascoe, Alice Mengi, Alma Auwun, Nalisa Neuendorf, John W. Bolnga, Moses Laman, Stephen J. Rogerson, Kamala Thriemer, Holger W. Unger

“…Transcripts were analysed using inductive and deductive thematic analysis applying a framework assessing: affective attitude, burden, ethicality, intervention coherence, opportunity costs, perceived effectiveness, and self-efficacy. …”
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