Chloride-dependent plasma membrane hyperpolarization confers superior salinity tissue tolerance in wild rice Oryza coarctata by Ping Yun, Celymar Angela Solis, Babar Shahzad, Lana Shabala, Meixue Zhou, Gayatri Venkataraman, Zhong-Hua Chen, Sergey Shabala

“…It is concluded that O. coarctata possesses a strong ability to discriminate between Cl− and Na+ uptake (a trait lacking in cultivated rice) and use it to maintain negative membrane potential (MP) values without activating H+-ATPase, thus enabling more efficient K+ retention in mesophyll with low energy costs. The above traits should be considered as potential targets in the rice breeding program for salt tolerance enhancement.…”
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Pre- and Postoperative Risk Factors for Hirschsprung-Associated Enterocolitis in Vietnamese Children by Hoang Tran Viet, Tuan Huynh Minh, Nhan Vu Truong, Anh Huynh Thi Phuong, Bich-Uyen Nguyen, Hao Chung The, Cong Phi Dang, Linh Truong Nguyen Uy

“…<b>Background/Objective</b>: Hirschsprung-associated enterocolitis (HAEC) can occur before and after surgery, increasing the complication rates, hospital stay, and treatment costs. This study aims to determine the incidence of preoperative and postoperative Hirschsprung-associated enterocolitis HAEC and the related risk factors. …”
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Practical Quantum Circuit Implementation for Simulating Coupled Classical Oscillators by Natt Luangsirapornchai, Peeranat Sanglaor, Apimuk Sornsaeng, Stephane Bressan, Thiparat Chotibut, Kamonluk Suksen, Prabhas Chongstitvatana

“…Numerical simulations agree with classical solvers across all tested configurations, indicating that this circuit-based Hamiltonian simulation approach can substantially reduce computational costs and potentially enable larger-scale many-body studies on future quantum hardware.…”
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Dual targeting of BCMA and SLAMF7 with the CARtein system: chimeric antigen receptors with intein-mediated splicing elicit specific T cell activation against multiple myeloma by Noelia Moares, Noelia Moares, Pablo Gonzalez-Garcia, Pablo Gonzalez-Garcia, Wenjie Yi-He, Wenjie Yi-He, Juan P. Muñoz-Miranda, Juan P. Muñoz-Miranda, Antonio Gabucio, Antonio Gabucio, Rosa Luna-Espejo, Javier Ocaña-Cuesta, Ricardo Fernandez-Cisnal, Cecilia M. Fernandez-Ponce, Cecilia M. Fernandez-Ponce, Francisco Garcia-Cozar, Francisco Garcia-Cozar

“…However, several barriers continue to limit the overall effectiveness of this approach, such as high production costs, prolonged manufacturing timelines, safety issues, and the potential for tumor antigen escape due to selective therapeutic pressure. …”
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Usage of the mobile phone on agricultural farm enterprise development by women in rural Bangladesh by Md. Sadekur Rahman, Md. Enamul Haque, Md. Safiul Islam Afrad, Shaikh Shamim Hasan, Md. Abiar Rahman, Md. Rubayet Al Ferdous Noman

“…Factors such as reduced transportation costs, time-saving, easy contact with stakeholders, and frequent contact with fellow entrepreneurs were identified as significant influences on rural women’s mobile phone usage. …”
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Assessment of Winery By-Products as Ingredients as a Base of “3S” (Safe, Salubrious, and Sustainable) Fermented Beverages Rich in Bioactive Anthocyanins by Berta María Cánovas, Irene Pérez-Novas, Cristina García-Viguera, Raúl Domínguez-Perles, Sonia Medina

“…The lack of proper valorisation alternatives entails high disposal costs and resource inefficiency that jeopardise the sustainability and competitiveness of the industry. …”
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Patient preferences and shared decision making for the traditional Chinese medicine treatment of lung cancer: A discrete choice experiment study by Yue Teng, Yan Wei, Yingyao Chen, Juntao Yan, Shimeng Liu, Fuming Li, Shiyi Bao, Yanfeng Ren, Liu Liu, Yi Yang

“…Patients showed strong preferences for increasing disease control rate, relieving nausea and vomiting, reducing the risk of side effects, and were concerned about monthly out-of-pocket costs. Subgroup analysis indicated that patients with a lower SDM-Q-9 score and those who were satisfied with medical services emphasized more importance of higher disease control rate. …”
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Diagnostic performance and clinical utility of metagenomic next-generation sequencing in suspected central nervous system infections: a prospective comparative study by Xiao-guang Cao, Xiong-feng Zhu, Zha Yu, Chun-yan Wang, Min Shao, Hua-dong Meng, Chong-jian Huang

“…Compared to the non-infection group, patients with CNS infections had significantly higher ICU admission(ICUA) rates, prolonged hospital stays, increased healthcare costs, and elevated rates of antibiotic adjustment and mNGS positivity (P&lt;0.05). …”
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Exploring the evolution of hollow fiber membrane applications in wastewater treatment by Fulufhelo H. Mudau, Zebron Phiri, Machawe M. Motsa, Lueta-Ann de Kock

“…Despite these advances, challenges such as membrane fouling, high operational costs, and limited scalability persist. Furthermore, integrating HFMs with pretreatment technologies and developing novel materials are pivotal for minimizing fouling and enhancing operational performance across various wastewater types. …”
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Drivers and consequences of nest ectoparasite pressure in tit nestlings by Sofía I. Arce, Jorge Garrido-Bautista, Catarina G. Cascão, Inês S.C. Vilhena, José Manuel Arjona, Ana Rita Cabral, Fábio Marengo, Joana Girão, Gregorio Moreno-Rueda, Jaime A. Ramos, Ana Cláudia Norte

“…Ectoparasites impose significant costs to their hosts and modulate their life-history traits. …”
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Reducing Postoperative Neurological Complications in Uniportal Full-Endoscopic Lumbar Interbody Fusion: Efficacy of the GUARD Technique Combined With Delayed Ligamentum Flavectomy by Hao-Chun Chuang, Yu-Chia Hsu, Yuan-Fu Liu, Chao-Jui Chang, Yu-Meng Hsiao, Yi-Hung Huang, Keng-Chang Liu, Chien-Min Chen, Hyeun Sung Kim, Cheng-Li Lin

“…Conclusion The GUARD technique and delayed ligamentum flavectomy significantly enhance patient safety by reducing postoperative radicular pain and neurapraxia without incurring additional costs. These techniques are easy to learn and integrate into existing surgical workflows, offering a valuable improvement for surgeons performing FE-TLIF procedures.…”
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Stem Cell Therapy for the Treatment of Amyotrophic Lateral Sclerosis: Comparison of the Efficacy of Mesenchymal Stem Cells, Neural Stem Cells, and Induced Pluripotent Stem Cells by Lauren Frawley, Noam Tomer Taylor, Olivia Sivills, Ella McPhillamy, Timothy Duy To, Yibo Wu, Beek Yoke Chin, Chiew Yen Wong

“…NSCs, isolated from the fetal spinal cord or brain, demonstrate promise in animal models but face functional integration and ethical challenges. iPSCs, created by reprogramming patient-specific somatic cells, offer a novel approach by potentially replacing or supporting neurons. iPSC therapy addresses ethical issues related to embryonic stem cells but encounters challenges regarding genotoxicity and epigenetic irregularities, somatic cell sources, privacy concerns, the need for extensive clinical trials, and high reprogramming costs. Conclusions: This research is significant for advancing ALS treatment beyond symptomatic relief and modest survival extensions to actively modifying disease progression and improving patient outcomes. …”
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Flight-Safe Inference: SVD-Compressed LSTM Acceleration for Real-Time UAV Engine Monitoring Using Custom FPGA Hardware Architecture by Sreevalliputhuru Siri Priya, Penneru Shaswathi Sanjana, Rama Muni Reddy Yanamala, Rayappa David Amar Raj, Archana Pallakonda, Christian Napoli, Cristian Randieri

“…Predictive maintenance (PdM) is a proactive strategy that enhances safety, minimizes unplanned downtime, and optimizes operational costs by forecasting equipment failures before they occur. …”
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An Artificial Intelligence Solution for Automated Dental Inspection and Charting by M.A. Moufti, M. Abu Talib, S. Al Mokdad, A. Alhouria, M. Alsaffarini, N. Almahmeed, S. Eldessouky, W. Kharoufah, Q. Nasir

“…This research presents a novel approach to automate dental inspection and charting, offering the potential to reduce clinical time and costs, improve patient experience and outcomes, and enhance patient access to dental care.…”
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Digital technologies commercially available in Germany in the context of nature conservation and ecosystem service provisioning in agriculture by Tsvetelina Krachunova, Tsvetelina Krachunova, Frauke Geppert, Frauke Geppert, Nahleen Lemke, Sonoko D. Bellingrath-Kimura, Sonoko D. Bellingrath-Kimura

“…The potentials for nature conservation and ecosystem service provisioning are still strongly supressed by non-sustainable barriers, e.g., high acquisition costs, practical maturity, mode of operation and infrastructure. …”
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Socio-economic burden of Rift Valley fever outbreak in a pastoralist community in Marsabit County, Kenya, 2018 by Mathew Munyamaara Mutiiria, Peter Gatongi, Elvis Oyugis, Mathew Muturi, Athman Mwatondo, Bernard Chege, Juster Mungiiria

“…Data was collected from 384 households. Direct and indirect costs were estimated using the economic model as described in Velthuis et al. (2008). …”
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Rapid and actionable nasal-swab screening supports antimicrobial stewardship in patients with pneumonia: a prospective study by Siyao Chen, Yuanyuan Xiao, Caixia Tan, Juan Zhou, Ting Liu, Sisi Zhang, Yiran Hu, Yang Liu, Ming Zheng, Letao Chen, Xinghui Gao, Yi-Wei Tang, Fred C. Tenover, Anhua Wu, Chunhui Li

“…Fewer renal injuries (1.33% vs. 8%; P = 0.015), and lower costs of antimicrobial agents ($621.78 vs. $881.70; P = 0.013) were observed in NG patients compared to those in the CG. …”
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Preliminary results of colostrum quality and passive immunity transfer in calves under tropical conditions by A. E. Guerrero-Pincay, S. A. Guamán-Rivera, C. D. Guilcapi-Carrillo, A. D. Feijoo-Leon, L. A. Moreira-García, J. Llivi-Marcatoma, C. O. Guerra Flores, A. F. Inca Falconí, B. R. Vaca Barahona, V. F. Noboa Silva

“…Abstract Inadequate management of livestock practices causes low colostrum quality and failure in passive transfer of immunity in calves, which increases mortality and production costs for farmers. Therefore, a study has been conducted in order to determine the effectiveness of passive transfer of immunity in the province of Orellana, Amazonian Ecuador. …”
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Reducing transmission expansion by co-optimizing sizing of wind, solar, storage and grid connection capacity by Aneesha Manocha, Gabriel Mantegna, Neha Patankar, Jesse D Jenkins

“…Co-locating storage with VREs also results in a 9%–13% increase in wind capacity, as wind sites tend to require longer and more costly interconnection. Finally, co-located storage exhibits higher value than standalone storage in our model setup (up to ∼43%–45%). …”
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A visualized machine learning model using noninvasive parameters to differentiate men with and without prostatic carcinoma before biopsy by Wenting Zhou, Linhui Wang, Xue Zhang, Xiaohong Zou, Xuemei Du, Liru Luo, Xiaolan Ye, Shujing Li, Hong Lv, Yuanfu Liu, Xiaoyang Huang

“…This model could aid in the precise selection of high-risk PCA patients for biopsy, potentially minimizing unnecessary procedures and their associated costs.…”
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