Utilizing X-ray radiography for non-destructive assessment of paddy rice grain quality traits by Murugesan Tharanya, Debarati Chakraborty, Anand Pandravada, Raman Babu, Mahantesh Gangashetti, Swapna Paidi, Sunita Choudhary, Kaliamoorthy Sivasakthi, Krithika Anbazhagan, Bhavani Vaditandra, Michael Waininger, Mareike Weule, Eva Hufnagel, Joelle Claußen, Jiří Vaněk, Thomas Wittenberg, Jana Kholova, Stefan Gerth

“…Such a non-destructive rice grain trait inference is expected to improve the robustness of paddy rice evaluation, as well as to reduce time and possibly costs for rice grain trait analysis. Furthermore, the described approach can also be transferred and adapted to other grain crops.…”
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Evidence based QUality Improvement for Prescribing Stewardship in ICU (EQUIPS-ICU): protocol for type III hybrid implementation-effectiveness study by Duncan Wagstaff, John Amuasi, Sumaiya Arfin, Diptesh Aryal, Mohd Basri Mat Nor, Joseph Bonney, Arjen Dondorp, David Dongelmans, Layoni Dullawe, Fathima Fazla, Aniruddha Ghose, Eva Hanciles, Rashan Haniffa, Madiha Hashmi, Adam Hewitt Smith, Bharath Kumar, Yen Lam Minh, Ramani Moonesinghe, Luigi Pisani, Cornelius Sendagire, Mohd Shahnaz Hasan, Maryam Shamal Ghalib, Moses Siaw Frimpong, Otavio Ranzani, Menbeu Sultan, David Thomson, Swagata Tripathy, Louise Thwaites, Rabiul Alam Md. Erfan Uddin, Mohd Zulfakar Mazlan, Wangari Waweru-Siika, Abigail Beane

“…Inappropriate prescribing is costly, exposes patients to unnecessary side-effects and drives population-level antimicrobial resistance, the prevalence and consequences of which are greatest in low- and middle-income countries. …”
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Impact evaluation of an interdisciplinary approach to patients with chronic non-cancer pain in Chilean primary care by Paula Zamorano, Teresita Varela, Isidora Salvatierra, Alvaro Tellez, Manuel Espinoza, Gustavo Torres, Victoria Rodríguez, María José Figueroa, Alejandro Rodríguez, Denisse Figueroa, Leonardo Silva, Sheila Salazar, Víctor Lucero, Francisco Suarez

“…In Chile, its prevalence is estimated at 34%, surpassing the prevalence of diabetes mellitus and hypertension. Its high costs reveal that clinical treatment causes the greatest economic impact, followed by days of work absenteeism. …”
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CRISPR-based assays for the detection of BK virus and JC virus infections post-kidney transplantation by Yu Liu, Jing-Song Xu, Li Cao, Shuang Yang, Tian-Ming Li, Hai-Qian Huang, Jun-Heng Zhang, Xue Zhao, Qian Liu, Shun Li, Min Li, Hua Wang

“…Conclusions These platforms incorporate molecular testing into the transplantation treatment model, thereby reducing costs, prolonging the survival time of the graft, improving the clinical outcomes of postoperative management in kidney transplantation, and enhancing the patients’ quality of life.…”
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Double diapering facilitates hip maturation in newborns by Wei Chun Lee, Hsuan Kai Kao, Mei Chun Chen, Wen E Yang, Shih Ming Chu, Chia Hsieh Chang

“…Conclusion: Double diapering enhances hip maturation and reduces clinical costs in newborns with physiological immature hips, but the therapeutic role for hip dysplasia requires further study.…”
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Air Quality and Healthy Ageing: Predictive Modeling of Pollutants Using CNN Quantum-LSTM by Fareena Naz, Muhammad Fahim, Adnan Ahmad Cheema, Bradley D. E. Mcniven, Tuan-Vu Cao, Ruth Hunter, Trung Q. Duong

“…The concept of healthy ageing is emerging and becoming a norm to achieve a high quality of life, reducing healthcare costs and promoting longevity. Rapid growth in global population and urbanisation requires substantial efforts to ensure healthy and supportive environments to improve the quality of life, closely aligned with the principles of healthy ageing. …”
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Barriers and opportunities related to access to oncology care in Benin: a qualitative study on breast cancer by Clémence Schantz, Freddy Houéhanou Rodrigue Gnangnon, Moufalilou Aboubakar, Anthelme Kouessi Agbodande, Paloma Puig, Justin Lewis Denakpo, Angéline Tonato Bagnan, Marie Bottin, Komi Mena Agbodjavou, Hélène Robin Sacca, Luis Teixeira, Valéry Ridde, the SENOVIE group

“…The current lack of radiotherapy requires patients in need to travel abroad for treatment. High costs of biomedical tests and treatments often lead to care abandonment, worsening health inequalities. …”
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Urinary 5-HIAA as a Potential Diagnostic Marker in Acute Appendicitis: A Preliminary Report of Its Promising Role in Early Detection by Murat Demir, Alper Gumus, Huseyin Kilavuz, Feyyaz Gungor, Sibel Yaman, Baki Ekci, Idris Kurtulus

“…Over the past few decades, diagnostic imaging has become a cornerstone in the identification of acute appendicitis, significantly contributing to the reduction in unnecessary laparotomies and associated healthcare costs. This study aimed to investigate the influence of serum and spot urine 5-hydroxyindoleacetic acid (5-HIAA) levels, as well as other established clinical and biochemical parameters on the diagnosis of acute appendicitis. …”
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Comparative Evaluation of Recombinant <i>Chlamydia abortus</i> and <i>Chlamydia trachomatis</i> Major Outer Membrane Proteins for Diagnosing Human Chlamydial Infection by Fernando M. Guerra-Infante, María J. de Haro-Cruz, Marcela López-Hurtado, Miguel A. De la Rosa-Ramos, Efrén Díaz-Aparicio, Beatriz Arellano-Reynoso

“…The recombinant MOMP ELISA could help identify women who had contact with <i data-eusoft-scrollable-element="1">C. trachomatis</i> or <i data-eusoft-scrollable-element="1">C. abortus</i> and could be a tool to lower the costs of performing molecular testing on all patients attending an infertility clinic.…”
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Mechanisms and Optimization of Foam Flooding in Heterogeneous Thick Oil Reservoirs: Insights from Large-Scale 2D Sandpack Experiments by Qingchun Meng, Hongmei Wang, Weiyou Yao, Yuyang Han, Xianqiu Chao, Tairan Liang, Yongxian Fang, Wenzhao Sun, Huabin Li

“…By innovatively integrating electrical resistivity tomography with HSV color mapping, this work achieves the first visualization of foam migration pathways in meter-scale heterogeneous reservoirs at a spatial resolution of ≤0.5 cm, reducing monitoring costs by approximately 30% compared to conventional CT techniques. …”
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Particularities in the “Oldie but Goldie” Tc-99m DMSA Renography: A Retrospective Reference Centre Overview of 931 Children by Irena Cristina Grierosu, Iuliana Magdalena Starcea, Wael Jalloul, Maria Adriana Mocanu, Roxana Alexandra Bogos, Tudor Ilie Lazaruc, Madalina Andreea Beldie, Ruxandra Tibu, Teodor Marian Ionescu, Cati Raluca Stolniceanu, Brindusa Casiana Acsinte, Cipriana Stefanescu, Alexandra Saviuc, Vlad Ghizdovat

“…A more accurate diagnosis allows for quicker treatment and prevention of potential complications, ultimately improving the quality of life and decreasing hospital costs of paediatric patients becoming adults.…”
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Unraveling the future productivity burden of cardiovascular disease in Qatar: Investigating the modifiable risk factors control in type 2 diabetes by Dina Abushanab, Daoud Al-Badriyeh, Danny Liew, Zanfina Ademi

“…The base-case model estimated the productivity burden of CVD, and interventional scenarios were simulated to assess potential gains resulting from improved control of modifiable risk factors, including reduced incidence of T2D, lower systolic blood pressure (SBP), decreased number of smokers, and reduced total cholesterol. All costs and outcomes were discounted at an annual rate of 3 %. …”
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Hospitalized with HIV in Zambia: individual and system factors driving the high burden of admissions and post-discharge mortality in the era of HIV epidemic control by Chiti Bwalya, Kirsten Stoebenau, Godfrey Muchanga, Mwangala Mwale, Choolwe Maambo, Swamie Banda, Palicha Halwiindi, Linah K. Mwango, Caitlin Baumhart, Nyuma Mbewe, Mundia Mwitumwa, Priscilla Mulenga, Manhattan Charurat, Wilbroad Mutale, Michael J. Vinikoor, Cassidy W. Claassen

“…Social-economic factors included economic shocks of hospitalization and post-discharge recovery, which compounded pre-existing poverty and high transportation and food costs. Conversely, disclosure of HIV status, better social support, a financially stable household, and hospital follow-up appointment reminders facilitated better post-discharge care. …”
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Community‐Level Compact City Design, Health Care Provision, and Outcomes of Patients With Stroke by Yukihiro Imaoka, Nice Ren, Soshiro Ogata, Shogo Watanabe, Tomoya Itatani, Eri Kiyoshige, Hirotoshi Imamura, Kunihiro Nishimura, Syoji Kobashi, Yasuyuki Kaku, Koichi Arimura, Hitoshi Fukuda, Masafumi Ihara, Tsuyoshi Ohta, Yuji Matsumaru, Nobuyuki Sakai, Takanari Kitazono, Shigeru Fujimoto, Kuniaki Ogasawara, Koji Yoshimoto, Akitake Mukasa, Koji Iihara

“…The association between WI and in‐hospital mortality, functional independence at discharge, and medical costs was assessed using multivariable mixed‐effects logistic regression model. …”
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Use of Injection of Hemostatic Gelfoam Mixture During Percutaneous Core Biopsy for Renal Tumors: A Comparative Retrospective Study of Outcomes Regarding Bleeding Complications, Hos... by Antonios Michailidis, Georgia Mingou, Eleni Tsakirmpaloglou, Panagiotis Kosmoliaptsis, Danae Makri, Ioannis Papadimitriou, George Dimou, Christos Giankoulof, Evangelos Petsatodis

“…These differences led to a notable reduction in total hospitalization days (43 vs. 167) and decreased overall costs. Diagnostic yield was similarly high in both groups (98.5% vs. 97.8%, <i>p</i> = 0.72). …”
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Analyzing foot care practices and diabetes management: a cross-sectional KAP study in a tertiary care hospital by Asma Malawi Alshahrani, Rajalakshimi Vasudevan, Afaf Aldahish, Yahia Alghazwani, Eman Shorog, N. Manusri, Rajeshri Dhurke, Puvvada Ranadheer Chowdary, Praveen Devanandan

“…IntroductionDiabetic foot complications, including foot ulcers and amputations, are significant contributors to morbidity and healthcare costs worldwide. Effective prevention requires comprehensive knowledge, positive attitudes, and consistent practices regarding foot care among diabetes patients. …”
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Livestock–cropland re-coupling and intensive farming: strategies for enhancing greenhouse gas mitigation and eco-efficiency in wheat–maize production in North China Plain by Beibei Wang, Peifang Wang, Hongxing He, Conrad Zorn, Wenzhou Guo, Jiarui Wu, Chaoqing Yu, Xiao Huang

“…However, in the North China Plain (NCP)—a key food hub in China—the disconnect between livestock farms and croplands limits manure recycling, obscuring its potential environmental benefits and economic costs. This study employs a life cycle assessment method to quantify GHG and ammonia emissions, SOC sequestration, economic performance, and the eco-efficiency of wheat–maize production in the NCP across six livestock–cropland coupling scenarios: farmers’ practice (FP), traditional household farming (HF), modern intensive decoupled systems with low (L), medium (M), and high (H) manure returning rates, and an intensive coupled system with optimum manure returning rate (IC). …”
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Cutoff levels for newborn screening of 21-OH deficiency in a Brazilian metropolitan area by Kallianna Paula Duarte Gameleira, Juliana de Vasconcellos Thomas, Vitor Guilherme Brito de Araújo, Cláudia Vicari Bolognani, Sérgio Eduardo Soares Fernandes, Fábio Ferreira Amorim

“…Conclusion: The proposed 17OHP cutoff strategy effectively reduced false positives, improving specificity, LR+, PPV, and accuracy Thus, it optimized CAHNBS programs while minimizing unnecessary costs and parental distress.…”
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Self-assembled and intestine-targeting florfenicol nano-micelles effectively inhibit drug-resistant Salmonella typhimurium, eradicate biofilm, and maintain intestinal homeostasis by Runan Zuo, Linran Fu, Wanjun Pang, Lingqing Kong, Liangyun Weng, Zeyuan Sun, Ruichao Li, Shaoqi Qu, Lin Li

“…The preparation process for the mixed micelles is simple and convenient compared with other existing nanodrug delivery systems, which can further decrease production costs. The optimized FTPPM demonstrated outstanding stability and sustained release. …”
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Development of a machine learning-based prediction model for serious bacterial infections in febrile young infants by Jina Lee, Jong Seung Lee, Seak Hee Oh, Jun Sung Park, Reenar Yoo, Soo-young Lim, Dahyun Kim, Min Kyo Chun, Jeeho Han, Jeong-Yong Lee, Seung Jun Choi

“…Urinalysis, C-reactive protein and procalcitonin were identified as top-tier features in the XGB model.Conclusions The ML-based prediction model demonstrated robust performance, with superior specificity and perfect sensitivity, which may enhance the accuracy of SBI detection and reduce the costs associated with false positives.…”
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