Clinical trials of broadly neutralizing monoclonal antibodies in people living with HIV – a review by Sharana Mahomed, Kayla Pillay, Razia Hassan-Moosa, Bruna P. G. V. Galvão, Wendy A. Burgers, Penny L. Moore, Melissa Rose-Abrahams, Carolyn Williamson, Nigel Garrett

“…While bNAbs show potential as an adjunct or alternative to ART, obstacles such as viral resistance, high production costs, and scalability must be addressed. Continued research is crucial to developing more potent, durable, and affordable bNAbs for sustainable HIV treatment and potential remission.…”
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Overview of antimicrobial resistance mitigation efforts in Benin 2024 by Alain K. Aissi, Tokpanou E.C. Koudjo, Filémon T. Tokponnon, Al Fattah Onifade, Akpeedje A.C. Wadagni, Géraud S.R. Padonou, Hervé A. Gbegnide, Léopold A. Azakpa, Adrien M. Hodonou, Roch C. Johnson, Francis M. Dossou

“…In Benin, high AMR rates to common antibiotics, including last-resort treatments, exacerbate infection outcomes and healthcare costs. Inappropriate antibiotic use worsens this challenge. …”
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Heat Treatment and Storage of Frass From Black Soldier Fly Larvae and Yellow Mealworm Production: Compliance With EU Regulation on Microbiological Quality and Safety by Ann De Volder, Jeroen De Smet, Lotte Frooninckx, David Deruytter, Johan Ceusters, Dries Vandeweyer

“…To ensure frass microbiological safety whilst preserving quality and reducing costs, tailored treatments seem appropriate. This may be no, milder, or more severe treatment, depending on the microbial load (counts and species type).…”
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Identification and Genetic Diversity Analysis of <i>Cucurbita</i> Varieties Based on SSR Markers by Jialong Zou, Xingting Wu, Xuejing Liu, Changcheng Peng, Yingxue Ma, Xiujie Zhang, Xuhong Yang, Shuailong Luo, Weigeng Xing, Hao Hong, Lang Li, Bin Tan, Ruonan Jing, Zhenjiang Xu

“…Our research results provide a new tool for population genetic analysis, variety identification, and protection in <i>Cucurbita</i> cultivars with high efficiency, accuracy, and lower costs compared to conventional methods.…”
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Implementation of the patient safety incident guideline in district health services, Western Cape by Robert J. Mash, Kaashiefah Adamson, Abdul Isaacs, Gavin Hendricks, Jani Fouche, Jennie Morgan, Klaus von Pressentin, Lawson Eksteen, Leigh Wagner, Liezel Rossouw, Luke Profitt, Marshall Lockett, Milton Groenewald, Mumtaz Abbas, Paddy Gloster, Paul Kapp, Stefanie Perold, Tracey-Leigh Abrahams, Werner Viljoen

“…Severity assessment code 1 were reported on time (median 24 h) and investigated promptly (median closure 4 days). Opportunity costs could be significant. While the system improved patient safety, it primarily focussed on behavioural interventions. …”
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Sustainability of Agropastoral Household Eco-Economic Systems: Integrated Assessment and Adaptive Management in Altay by Bo Nan, Zihan Yang, Chenchen Peng, Zhilong Wu, Ying Hou, Bo Li, Hongjie Wang

“…Cash crop cultivation with substitute grazing (CS) achieved the highest profitability but imposed severe environmental costs. Artificial forage cultivation with nonagricultural activities and substitute grazing (ANS) produced high unit productivity but inefficient resource utilization. …”
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Saffron (Crocus sativus L.): The golden spice — management, challenges, and opportunities for sustainable production in the United States by Bharat Sharma Acharya, Arash Ghalehgolabbehbahani, Said Hamido, Gladis Zinati, Arianna Bozzolo, Leigh Archer, Kristie Wendelberger, Saurav Das, Resham Thapa, Dinesh Panday

“…However, global saffron cultivation is challenged by climate change, rising labor costs, global supply chain disruptions, and product adulteration, emphasizing the need for multi-disciplinary research to understand and maximize the potential of saffron production. …”
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An examination of former prisoners’ mental health problems before death by suicide over a 21-year period (2001–2021) by Alison Baird, Lana Bojanić, Saied Ibrahim, Jessica Kenworthy, Pauline Turnbull, Navneet Kapur, Louis Appleby, Jenny Shaw, Daniel Pratt

“…The link with deprivation is striking at a time at which rising costs of living are resulting in more health inequalities. …”
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Biomarker for renal scarring screening in children with vesicoureteral reflux: a systematic review by Utari Mudhia Arisa Putri, Putu Angga Risky Raharja, Gerhard Reinaldi Situmorang, Irfan Wahyudi, Arry Rodjani, Henny Adriani Puspitasari, Abubakr Imam, Luis R. Saraiva, Luis R. Saraiva, Luis R. Saraiva, Santiago Vallasciani, Santiago Vallasciani, Tariq O. Abbas, Tariq O. Abbas, Tariq O. Abbas

“…Although traditional imaging techniques, such as dimercaptosuccinic acid (DMSA) scans, are regarded as the gold standard for identifying renal scarring, they come with risks of radiation exposure and high costs. This review investigates the diagnostic accuracy of blood and urine biomarkers as alternative methods for detecting renal scarring in VUR.MethodsThis systematic review adhered to the PRISMA 2020 guidelines. …”
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Programmatic mapping and size estimation of people who inject drugs to plan targeted HIV prevention and harm reduction programs in iran, a nationwide study by Nima Ghalekhani, Ahmad Hajebi, Ebrahim Ghodusi, Behnaz Beygi, Toktam Khojasteh Bojnordi, Mohammad Farooq Mashhour, Fatemeh Rezaei Sharif, Farzaneh Rajabzadeh, Hooriyeh Khoshdel, Hamid Reza Fathi, Hamid Sharifi

“…Conclusions This study provides conclusive evidence that the current spatial distribution of harm reduction services for PWID in Iran is inefficient, characterized by significant coverage gaps in high-risk areas alongside costly resource redundancy through service overlap. …”
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Influence of L-tryptophan use on the dynamics of cognitive functions in the complex therapy of delayed psycho-speech development in children by V. M. Polyakov, L. V. Rychkova, T. A. Belogorova, V. I. Mikhnovich, O. V. Bugun, O. N. Berdina, Zh. V. Prokhorova, T. A. Teterina, L. N. Lebedeva, L. I. Lebedeva

“…Two-week L-tryptophan intake in complex therapy of DPSD in children can significantly improve the cognitive activity, and greatly increase both the effectiveness and sustainability of treatment outcomes, which will significantly reduce the time and frequency of hospitalization and financial costs for the rehabilitation of this patients.…”
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Depth-Guided Monocular Object Pose Estimation for Warehouse Automation by Phan Xuan Tan, Dinh-Cuong Hoang, Anh-Nhat Nguyen, Eiji Kamioka, Ta Huu Anh Duong, Tuan-Minh Huynh, Duc-Manh Nguyen, Duc-Huy Ngo, Minh-Duc Cao, Thu-Uyen Nguyen, Van-Thiep Nguyen, Duc-Thanh Tran, Van-Hiep Duong, Anh-Truong Mai, Duc-Long Pham, Khanh-Toan Phan, Minh-Quang Do

“…However, RGBD-based methods require specialized depth sensors, which can be costly and may not function reliably in warehouse environments with reflective surfaces, varying lighting conditions, or sensor occlusions. …”
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Optimizing Milling Parameters and Halloysite Nanotube Concentration to Enhance Surface Quality and Reduce Energy Consumption by Laura Peña-Parás, Martha Rodríguez-Villalobos, Demófilo Maldonado-Cortés, Jaime A. González-García, Mónica Herrera-Maldonado, Gabriela Trousselle-Strozzi, Oscar E. Montemayor, Ángel G. Romero-Cantú, Daniel I. Quintanilla-Correa

“…This optimization provides significant benefits, including reduced production costs, improved part quality, and a lower carbon footprint in the manufacturing process.…”
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Knowledge of legal rights as a factor of refugee and asylum seekers’ health status: a qualitative study by Tara C Pilato, Faten Taki, Kaitlyn Sbrollini, Amanda Purington Drake, Brian Maley, Stephen Yale-Loehr, Jane L Powers, Natalya N Bazarova, Aparajita Bhandari, Gunisha Kaur

“…Several impediments to accessing healthcare and public benefits were identified, including pragmatic barriers (such as prohibitive costs or lack of insurance), knowledge gaps and mistrust of healthcare systems.Conclusions There is low health engagement by refugees and asylum seekers, as a result of multiple, complex factors impeding the ability of refugee and asylum seekers to access healthcare and other public benefits for which they are eligible—with resultant detrimental health effects. …”
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Comparative assessment of the signs of instability of atherosclerotic plaques in the carotid arteries in elderly patients with acute coronary syndrome with duplex scanning and comp... by E. V. Konstantinova, A. A. Sagatelyan, A. A. Bogdanova, E. S. Pershina, V. S. Shemenkova, A. V. Svet, A. A. Oganesyan, M. Yu. Gilyarov

“…It is possible to use DUS as a routine method for assessing carotid atherosclerosis in patients of this group, which can reduce the risk of complications during CT, shorten the examination time, and minimize economic costs.…”
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AI‐assisted warfarin dose optimisation with CURATE.AI for clinical impact: Retrospective data analysis by Tiffany Rui Xuan Gan, Lester W. J. Tan, Mathias Egermark, Anh T. L. Truong, Kirthika Kumar, Shi‐Bei Tan, Sarah Tang, Agata Blasiak, Boon Cher Goh, Kee Yuan Ngiam, Dean Ho

“…CURATE.AI may facilitate the effective use of affordable warfarin with a well‐established safety profile, without the need for costly, new oral anticoagulants. This can have significant impact both on the individual and public health.…”
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Transitioning apple farming towards sustainability: evidence from Himachal Pradesh, India by Divyanshu, Rohit Kumar Vashishat, Subhash Chander Verma, Rajeshwar Singh Chandel, Subhash Sharma, Sudhir Verma, Narender Bharat, Kuldeep Singh Thakur, Inder Dev, Sanjeev Chauhan, Prashant Sharma, Kamal Kishore, Ashu Chandel, Pramod Sharma

“…The Apple + Vegetables combination under NF resulted in a 31.29% increase in net returns and a 27.55% reduction in production costs, primarily due to the elimination of chemical inputs. …”
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Insurance Payor Status and Outcomes in Pediatric Sports-Related Injuries: A Rapid Review by Katherine M. Kutzer, Lulla V. Kiwinda, Daniel Yang, John Kyle Mitchell, Emily J. Luo, Emily J. Harman, Stephanie Hendren, Kendall E. Bradley, Brian C. Lau

“…<b>Introduction</b>: The rise in youth sports participation has led to an increase in pediatric sports-related injuries in the United States, contributing to growing healthcare costs and exacerbating socioeconomic disparities. …”
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Microbial contamination of unsterile vs sterilized 3M™ Micropore™ tape on full-thickness skin graft donor wound: Clinical trial and evaluation by Graciella Novian Triana Wahjoe Pramono, Betha E. Riestiano, Hardisiswo Soedjana, Leonardus Widyatmoko, Sandy Sopandi

“…Sterile tapes in developing countries are harder to find and more costly. Whether unsterile tape is safe to use on fresh wounds is an ongoing debate. …”
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Factors associated with secondary thoracotomy for hemostasis following lung surgery: a retrospective analysis by Junwei Xie, Junwei Xie, Junwei Xie, Hongliang Wang, Tianci Han, Wei Tong, Xiaoqi Guo, Min Zhang, Dongzhe Liu, Liang Zhang, Liang Zhang, Liang Zhang, Hongxu Liu, Hongxu Liu, Hongxu Liu

“…Although infrequent, secondary thoracotomy can lead to prolonged hospitalization, increased costs, and additional patient trauma. However, prior research has been limited to case reports or experience-based summaries, lacking a comprehensive analysis of this issueMethodsA retrospective analysis was conducted on 39 patients who underwent secondary thoracotomy for hemostasis between January 2015 and December 2022 at the Cancer Hospital of China Medical University. …”
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