Artificial intelligence-based epitope discovery of Mpox virus: Rational vaccine design by Adane Adugna, Desalegn Abebaw, Abebaw Admasu, Bantayehu Addis Tegegne, Zigale Hibstu Teffera, Tiruzer Hibstu, Gelagey Baye, Baye Ashenef, Enyew Fenta Mengistu, Mohammed Jemal

“…Traditional vaccine development methods can be both costly and time-consuming; however, advancements in genomic and proteomic data processing, particularly through artificial intelligence (AI), offer new avenues for rapid epitope discovery and vaccine design. …”
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A Parameter-Free Topological Disassembly-Guided Method for Hyperspectral Target Detection by Xiaotong Sun, Lina Zhuang, Lianru Gao, Hongmin Gao, Xu Sun, Bing Zhang

“…Traditional model-driven methods often underperform due to the mismatches between model assumptions and real data, while data-driven methods face challenges such as complex training processes, parameter tuning, and high computational costs. To address these challenges, this article adopts a model-free and parameter-free design philosophy. …”
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The complex influence of external and internal electricity networks on the magnetic field level in residential premises of buildings by V. Yu. Rozov, D. Ye. Pelevin, S. Yu. Reutskiy, K. D. Kundius, A. O. Vorushylo

“…The implementation of the proposed methodology will allow to reduce the calculated coefficient of normalization of the MF of individual electricity networks by 25–50 %, which, in turn, will contribute to the reduction of economic costs for engineering means of normalizing the summary MF in residential premises, caused by the influence of the group of electricity networks. …”
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Stapled Haemorrhoidopexy in Germany by Johannes Jongen, Jessica Schneider, Volker Kahlke, Tilman Laubert

“…In addition, a randomised controlled trial showed that the advantage of SH (less pain and shorter period off-work) compared to EH declined during follow up and the costs of SH were higher than that of EH. Today SH still has its place in surgery of haemorrhoidal disease (HD), but the indication for the procedure has been limited and should be critically discussed with the patient. …”
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Optimization of Anthocyanin Extraction from Purple Sweet Potato Peel (<i>Ipomea batata</i>) Using Sonotrode Ultrasound-Assisted Extraction by Raquel Lucas-González, Mirian Pateiro, Rubén Domínguez-Valencia, Celia Carrillo, José M. Lorenzo

“…Optimising their extraction can enhance yield and reduce costs. The current work aimed to optimize anthocyanin and antioxidant recovery from PSPP using a Box-Behnken design and sonotrode ultrasound-assisted extraction (sonotrode-UAE). …”
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Smart city rankings and startup ecosystems: An empirical analysis of inverse correlation across 77 smart cities by Aleksandra Kuzior, Viktoriia Marhasova, Viera Zozuľakova, Maria Kočnerova, Vitaliia Koibichuk, Lyudmila Ryabushka, Tetiana Vasylieva

“…One possible explanation is that smart cities, dominated by large tech players and rigid governance structures, may present entry barriers for emerging startups. High operational costs, regulatory constraints, and a focus on large-scale infrastructure projects may disincentivize startups from localizing their innovations within these environments. …”
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A New Approach for Estimation of Physical Properties of Irregular Shape Fruit by Hieu M. Tran, Kien T. Pham, Thanh M. Vo, Tat-Hien Le, Tri T. M. Huynh, Son Vu Truong Dao

“…Manual property measurements are time-consuming, costly, and labor-intensive due to traditional technologies while various devices need to be installed to adapt process requirements. …”
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Img2Side: A Transfer Learning Based Model for Predicting Drug Side Effects Using 2D Chemical Structural Images by Muhammad Asad Arshed, Muhammad Ibrahim, Shahzad Mumtaz, Tenvir Ali, Gyu Sang Choi

“…DSEs impact on public health and healthcare can prove costly. These DSEs can be an important factor in the failure/acceptance of drugs. …”
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Acute alcohol intoxication among adolescents in Italy, the Netherlands and Belgium: a cross-national hospital chart comparison study by Stijn Verhulst, Nico van der Lely, Andrea Orsi, Giancarlo Icardi, Guido Van Hal, Hanna van Roozendaal, Louise Pigeaud, Allegra Ferrari, Loes de Veld, Inge Glazemakers, Jozef De Dooy

“…Background Excessive drinking among adolescents in Western Europe is prevalent, posing significant health risks and societal costs. Comprehensive data on adolescent drinking patterns is crucial for developing effective prevention strategies. …”
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Novel Approach Methodologies in Modeling Complex Bioaerosol Exposure in Asthma and Allergic Rhinitis Under Climate Change by Esra Atalay-Sahar, Ece Yildiz-Ozturk, Su Ozgur, Arzu Aral, Emre Dayanc, Tuncay Goksel, Ralph Meuwissen, Ozlem Yesil-Celiktas, Ozlem Goksel

“…Additionally, NAMs improve preclinical study outcomes by offering higher throughput, reduced costs and greater reproducibility, enhancing the translation of data into clinical applications. …”
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Leveraging Synthetic Data to Develop a Machine Learning Model for Voiding Flow Rate Prediction From Audio Signals by Marcos Lazaro Alvarez, Alfonso Bahillo, Laura Arjona, Diogo Marcelo Nogueira, Elsa Ferreira Gomes, Alipio M. Jorge

“…Sound-based uroflowmetry (SU) is a non-invasive technique emerging as an alternative to traditional uroflowmetry (UF) to calculate the voiding flow rate based on the sound generated by the urine impacting the water in a toilet, enabling remote monitoring and reducing the patient burden and clinical costs. This study trains four different machine learning (ML) models (random forest, gradient boosting, support vector machine and convolutional neural network) using both regression and classification approaches to predict and categorize the voiding flow rate from sound events. …”
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A survey of the cytotoxicity of some medicinal plant extracts in Ghana against breast and prostate cancer cells by Kwadwo Fosu, Bridget Agbesi, Richard Gyan, Ebenezer Eduam Afful, Fussein Hussein, Daniel Takyi, Eric Frimpong, Ann Deborah Darko, Cosmos Nuer, Joshua Nsiah, Divine Yao Sapey, Foster Kyei

“…Current treatments are limited by high costs, resistance, and adverse effects hence prompting the exploration of alternative therapies. …”
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National temperature neutrality, agricultural methane and climate policy: reinforcing inequality in the global food system by Colm Duffy, Carl Doedens, Róisín Moriarty, Hannah Daly, David Styles, Malte Meinshausen

“…The study concludes that the TN approach is not a robust basis for fair and effective national climate policy, and risks a potentially costly underestimation of both long-term CH _4 mitigation and carbon dioxide removal in the context of national planning for an equitable, sustainable, food secure future.…”
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Transcriptome Sequencing-Based Analysis of Premature Fruiting in <i>Amomum villosum</i> Lour. by Yating Zhu, Shuang Li, Hongyou Zhao, Qianxia Li, Yanfang Wang, Chunyong Yang, Ge Li, Yanqian Wang, Lixia Zhang

“…., a perennial medicinal plant in the Zingiber genus, usually requires approximately 3–4 years of vegetative growth from seed germination to first fruiting, resulting in high initial investment costs and a prolonged revenue cycle, which pose significant challenges to the industry’s sustainable development. …”
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Accurate estimation of permeability reduction resulted from low salinity water flooding in clay-rich sandstones by Xiaojuan Zhang, Muntadher Abed Hussein, Tarak Vora, Anupam Yadav, Asha Rajiv, Aman Shankhyan, Sachin Jaidka, Mehul Manu, Farzona Alimova, Issa Mohammed Kadhim, Zainab Jamal Hamoodah, Fadhil Faez, Ahmad Khalid

“…Traditional methods often rely on costly experiments or simplified empirical correlations, which struggle to capture the complex, non-linear interactions governing this phenomenon. …”
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Application of Twisting Controller and Modified Pufferfish Optimization Algorithm for Power Management in a Solar PV System with Electric-Vehicle and Load-Demand Integration by Arunesh Kumar Singh, Rohit Kumar, D. K. Chaturvedi, Ibraheem, Gulshan Sharma, Pitshou N. Bokoro, Rajesh Kumar

“…The main drivers of the increase in solar photovoltaic (PV) system grid integrations in recent years have been lowering energy costs and pollution. Active and reactive powers are controlled by a proportional–integral controller, whereas energy storage batteries improve the quality of energy by storing both current and voltage, which have an impact on steady-state error. …”
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Reducing oral corticosteroids in severe asthma (ROSA Project): a nationwide Portuguese consensus by Claudia Chaves Loureiro, Manuel Branco Ferreira, Jorge Ferreira, Ricardo Lima, João Marques, Anna Sokolova, Fernanda S. Tonin, Filipa Duarte Ramos

“…Monitoring patients’ comorbidities was rated as imperative by all experts.Conclusions : These results can guide an update on asthma management in Portugal and should be supplemented by studies on therapy access, patients’ adherence, and costs.…”
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Temperature analysis and ampacity evaluation of HV cable joints based on thermal flow coupling and measurable data by Zhanlong Zhang, Hui Zhao, Yu Yang, Xueli Liu, Jiayi Xiao

“…However, owing to limitations in modelling techniques and measurement capabilities, the digital model of cable joints necessitates the use of parameters that are difficult to obtain, resulting in limited accuracy, high costs, and poor interpretability. Therefore, in this study, a digital model is constructed on the basis of thermal–flow coupling and measurable data, and an ampacity evaluation method is proposed. …”
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The Application of Extraperitoneal Ostomy Combined with Pelvic Peritoneal Reconstruction in Laparoscopic Abdominoperineal Resection for Rectal Cancer by Sen Wang, Qingyang Meng, Jun Gao, Yuqin Huang, Jie Wang, Yang Chong, Youquan Shi, Huaicheng Zhou, Wei Wang, Dong Tang, Daorong Wang

“…To prevent the complications and reduce surgical costs of LAPR, we performed some modifications for it. …”
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Nephrology Health Professionals’ Perspectives on Their Preferred Modality for Scientific Meetings, Balancing Affordability, Sustainability and Opportunities to Interact With Peers:... by Patrizia Natale, Massimo Torreggiani, Suetonia Palmer, Martin Howell, Allison Jaure, Dominique Tudor, Silvia Salaro, Elisa Longhitano, Cristina Adriana Popa, Giovanni Strippoli, Rosanna Coppo, Giorgina B. Piccoli

“…In-person meetings allow for discussions with international peers, although costs may be a barrier. The wiser use of resources and better management of large numbers of attendees were the main advantages of hybrid meetings (about 30% each); however, this modality potentially discriminates on the basis of financial resources and geographical area (31%). …”
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