Diagnostic value of CD138 and GATA3 in benign prostatic hyperplasia and prostate cancer by Yang Hu, Luo Dan, Yang Shikun, Lian Junbo, Huo Shuangjie, Dong Liru

“…Results In BPH samples, nuclear expression of GATA3 and p63 showed identical positive rates (92.21%, 95%CI: 89.3–94.8%), while CD138 (antibody concentration 1:200) and CK34βE12 (antibody concentration 1:100) demonstrated cytoplasmic/membranous positivity in 96.10% (93.4–98.1%) and 93.51% (90.2–95.9%) of cases respectively. …”
Get full text

Low dietary calcium intake leads to a higher colorectal cancer burden in countries with low social development: findings from the Global Burden of Disease Study 2021 by Junhong Wu, Ziyi Zhang, Jiong Chen, Shiya Yu, Donglin Liu, Junhui Jiang, Tingting Liu, Hu Zhao, Hu Zhao, Yu Wang, Yu Wang

“…Joinpoint regression analysis was conducted to assess temporal patterns in disease burden. Estimated annual percentage changes (EAPCs) were calculated to quantify the rate of change in relevant indicators. …”
Get full text

Factors affecting detection probability: Insights from banding data in a long-term continent-wide monitoring program by Morgane Gicquel, Juan C. Alonso, Lovisa Nilsson, Matthew Low, Javier A. Alonso, Dmitrijs Boiko, Damon Bridge, Patrick Dulau, Thomas Heinicke, Anne Kettner, Yosef Kiat, Petras Kurlavičius, Sigvard Lundgren, Michael Modrow, Günter Nowald, Ivar Ojaste, Alain Salvi, Jostein Sandvik, Markéta Ticháčková, Antonio Torrijo, Jari Valkama, Zsolt Végvári, Johan Månsson

“…In this study we investigate factors influencing detection rates of colour-banded Eurasian cranes (Grus grus), from a monitoring program spanning 35 years, involving 5049 marked individuals using four different types of bands (ELSA, ‘Finnish’, ‘Spanish’ and alphanumeric) with 172,725 resightings along migratory flyways. …”
Get full text

Controlled-release fertilizer affects leaf nitrogen allocation and photosynthesis to improve nitrogen use efficiency and yield in the sunflower field by Wenhao Ren, Xianyue Li, Xianyue Li, Xianyue Li, Tingxi Liu, Tingxi Liu, Ning Chen, Maoxin Xin, Qian Qi, Bin Liu

“…IntroductionNitrogen (N) can significantly affect the photosynthetic rate (Pn) of plants. Under traditional nitrogen fertilization (TNF) or inappropriate nitrogen application, leaf N is often redistributed to support the seed protein accumulation rather than the photosynthesis in the later stages of crop growth. …”
Get full text

Gastric Cancer Mortality in Ceará in Brazil’s Northeastern, 2000-2022: Spatio- Temporal Study by Lucia Libanez Bessa Campelo Braga, Helio De Almeida Nobre Junior, Jorg Heukelbach, Anderson Fuentes Ferreira, Ana Suzete Lopes, Edson Luiz de Oliveira, Vitor de Sousa Tomé, Taynara Lais Silva, Daniele Calheiros Campelo Maia, Alberto Novaes Ramos Júnior

“…The highest mortality rates were found in the southern parts of the state and around a northern major urban center. …”
Get full text

Genomic data suggest parallel dental vestigialization within the xenarthran radiation by Emerling, Christopher A, Gibb, Gillian C, Tilak, Marie-Ka, Hughes, Jonathan J, Kuch, Melanie, Duggan, Ana T, Poinar, Hendrik N, Nachman, Michael W, Delsuc, Frédéric

“…These genomic data provide evidence for multiple pathways and rates of anatomical regression, and underscore the utility of using pseudogenes to reconstruct evolutionary history when fossils are sparse. …”
Get full text

Development of prediction models for screening depression and anxiety using smartphone and wearable-based digital phenotyping: protocol for the Smartphone and Wearable Assessment f... by Sujin Kim, Ah Young Kim, Yu-Bin Shin, Seonmin Kim, Min-Sup Shin, Jinhwa Choi, Kyung Lyun Lee, Jisu Lee, Sangwon Byun, Heon-Jeong Lee, Chul-Hyun Cho

“…However, their detection and diagnosis rates remain low owing to the limitations of the current screening methods. …”
Get full text

Characteristics and Outcomes of People With COPD Who Experience Exacerbations While on Inhaled Triple Therapy: Results of the SIRIUS I Cohort Study in the US (2015–2019) by Nordon C, Carstens D, Fagerås M, Müllerová H, Veeranki PS, Alves JA, Germack HD, Barnes TL, McCormack MC

“…Baseline characteristics and treatment patterns, crude incidence rates (IRs) for exacerbations and mortality (per 100 person-years [PYs]; variable follow-up), and HCRU and costs (12-month follow-up) were summarized descriptively.Results: Of 4,920 patients in the TT cohort, mean (SD) age was 62.3 (9.7) years, 60.9% were female, and 68.0% were white; 46.5% of TT cohort patients with a history of smoking were current smokers. …”
Get full text

The impact of COVID-19 pandemic on mortality among adults receiving care for chronic health conditions in rural South Africa: findings from Agincourt health and socio-demographic s... by Daniel Ohene-Kwofie, Cyril Chironda, Jean Bashingwa, Tshegofatso Seabi, Audry Dube, Beth Tippett-Barr, Francesc Xavier Gómez-Olivé, Kathleen Kahn, Stephen Tollman, Chodziwadziwa W. Kabudula

“…Mortality rate among persons with HIV, and diabetes or hypertension increased by up to 26% and 70%, respectively during the COVID-19 pandemic period, particularly among women. …”
Get full text

The resurgence of Lassa fever in Nigeria: economic impact, challenges, and strategic public health interventions by Stanley Chinedu Eneh, Stanley Chinedu Eneh, Stanley Chinedu Eneh, Chidera Gabriel Obi, Chidera Gabriel Obi, Udokang Ephraim Ikpongifono, Udokang Ephraim Ikpongifono, Zakariya’u Dauda, Zakariya’u Dauda, Samson Adiaetok Udoewah, Samson Adiaetok Udoewah, Collins Chibueze Anokwuru, Collins Chibueze Anokwuru, Francisca Ogochukwu Onukansi, Francisca Ogochukwu Onukansi, Ogechi Vinaprisca Ikhuoria, Ogechi Vinaprisca Ikhuoria, Temitope Olumuyiwa Ojo, Chukwuocha Uchechukwu Madukaku, Ibuchukwu Nkeonyenasoya Orabueze, Ibuchukwu Nkeonyenasoya Orabueze, Amara Frances Chizoba

“…Recent data from the Nigeria Centre for Disease Control and Prevention (NCDC) indicates 1,171 suspected cases, 290 confirmed cases, and 53 deaths between January 6 to 26, 2025, with a case fatality rate of 18.3%. Lassa fever transmission is highly seasonal, peaking during the dry months when food scarcity drives rodent-human interactions. …”
Get full text

Mannheim Peritoneal Index in the Prediction of Postoperative Complications in Patients with Peritonitis by N. N. Aksenova, F. R. Akhmerov, M. V. Maleyev

“…In patients with local postoperative complications being developed, the MPI values were higher (p<0.05) than in those without them. The mortality rates that have been predicted by means of MPI (16.3%) and actual (15.2%) are actually in agreement. …”
Get full text

Amazon Rainforest Exchange of Carbon and Subcanopy Air Flow: Manaus LBA Site—A Complex Terrain Condition by Julio Tóta, David Roy Fitzjarrald, Maria A. F. da Silva Dias

“…We tested the hypothesis that horizontal drainage flow over this study area is significant and can affect the interpretation of the high carbon uptake rates reported by previous works at this site. A similar experimental design as the one by Tóta et al. (2008) was used with a network of wind, air temperature, and CO2 sensors above and below the forest canopy. …”
Get full text

TS-InSAR assessment of groundwater overexploitation-land subsidence linkage: Hengshui case study by Yan An, Qiang Shen, C.K. Shum, Fan Gao, Xu Zhang, Liming Jiang, Hansheng Wang

“…New hydrological insights for the region: Results show subsidence dominates in Hengshui City, with rates up to 141 mm/year (2017–2024), mainly due to falling confined aquifer heads and delayed aquitard drainage. …”
Get full text

Effect of nonpharmaceutical interventions on the epidemic trends of scarlet fever in China: a population-based surveillance and modelling study by Xiaojuan Zhang, Yuanhai You, Jie Liu, Lu Sun, Haijian Zhou, Xingxing Zhang, Bike Zhang

“…Findings: During 2005-2024, 876,680 cases were reported (crude annual incidence: 3.22/100 000). The annual morbidity rates for three periods were 3.56, 1.58, and 3.25/100 000. …”
Get full text

High-risk HPV distribution and importance of continuing cervical cancer screening of women aged 65 years and older: a study based on 2 152 766 women in China by Bo Wu, Yu Jiang, Jiahui Wang, Xiaotian Li, He Wang, Fanghui Zhao, Zichen Ye, Yingyu Zhong, Shuyan Jin, Xuelian Zhao, Yueyun Wang

“…The hr-HPV prevalence in women aged≥65 was 13.67%, with a CIN2+ detection rate of 3.33‰ and a cancer rate of 0.92‰, compared with 8.08%, 1.55‰ and 0.1‰, respectively, in women aged<65 (all p<0.001). …”
Get full text

Thermo-hydro-mechanical coupling mechanisms and sensitivity analysis of abandoned mine thermal energy storage systems by Liyuan LIU, Yaohui LI, Tao WANG, Tongbin ZHAO, Qiang KOU, Zerui MI, Le ZHANG

“…A three-dimensional thermo-hydro-mechanical (THM) coupled numerical model is developed to calculate the coupled effects over a decade of system operation and analyze heat transfer processes along with stress variation patterns in the roadway’s surrounding rock. Results indicate that the MTES system effectively utilizes geothermal environments for high-efficiency storage of waste heat, achieving a residual temperature of 35.5 ℃ (44.4% retention rate) during the first year following the injection of 80 ℃ water, with winter extraction temperatures progressively increasing annually. …”
Get full text

Optimizing Effects of Organic Farming and Moderately Low Nitrogen Levels on Soil Carbon and Nitrogen Pools by Guanghua Wang, Yu Yang, Yuqi Chen, Shilong Yu, Xiaomin Huang, Min Jiang, Zujian Zhang, Lifen Huang

“…Therefore, a field trial was conducted to elucidate the impacts of different cultivation patterns and nitrogen application rates on soil carbon and nitrogen pools, especially on how these factors affect the components of soil organic carbon. …”
Get full text

Role of TRP channels and HSPs in thermal stress response in the aphid parasitoid Aphelinus asychis (Hymenoptera: Aphelinidae) by Xiang LIU, Zhi-wei KANG, Xing-lin YU, Fan LI, Tong-xian LIU, Qiang LI

“…The results showed that the maximum temperature that allowed A. asychis survival was approximately 41°C; females had higher survival rates than that of the males at 40 and 41°C. Short-term heat-shock resulted in increased expression of Aasyshsp in males, and Aasyhsp40, Aasyhsp68, Aasyhsp70-4, Aasyhsp70-5 and Aasyhsp90 were upregulated and then downregulated, whereas Aasyhsp70-3 was upregulated at 41°C. …”
Get full text

A Permutation Entropy Method for Sleep Disorder Screening by Cristina D. Duarte, Marcos M. Meo, Francisco R. Iaconis, Alejandro Wainselboim, Gustavo Gasaneo, Claudio Delrieux

“…<b>Conclusions:</b> The advantages of this approach, including compatibility with single-channel EEG (enabling potential wearable applications), independence from sleep-stage annotations, and generalizability across recording montages and sampling rates, stablish a framework for non-specific sleep pathology detection. …”
Get full text

Laboratory based antimicrobial resistance surveillance for Pseudomonas aeruginosa blood isolates from South Africa by Ashika Singh-Moodley, Adriano Duse, Preneshni Naicker, Ranmini Kularatne, Trusha Nana, Ruth Lekalakala, Nontombi Mbelle, Halima Dawood, Khine Swe Swe Han, Praksha Ramjathan, Prathna Bhola, Andrew Whitelaw, Olga Perovic

“…Pseudomonas aeruginosa is an opportunistic healthcare-associated pathogen with high rates of morbidity and mortality and an extensive range of resistance mechanisms. …”
Get full text